Implications of Medical Low Dose Radiation Exposure

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Report on optimisation of multi-modality imaging

Report on optimisation of multimodality imaging

Midterm recruitment report. Recruitment applies only to the nested case control study
Report on estimated doses for the case-control study subjects
Report on status of posting results in the study registry(s) for WP5

Report on status of posting results in the study registrys for WP5

Report on the current use of multi-modality systems in nuclear medicine
Update of administered activity-to-organ-dose conversion factors for two commonly used radiopharmaceuticals

Update of administered activitytoorgandose conversion factors for two commonly used radiopharmaceuticals

Report on results of the analysis miRNA and lncRNA
MEDIRAD Second Recommendations
Guidelines and recommendations for quantitative I-131 imaging and dosimetry
Midterm recruitment report for radiopharmaceutical dosimetry study
MEDIRAD Third Recommendations
Comprehensive Reporting Templates and Pilot system for SR-Reporting
Report on a) the organ dose data representation and b) collected organ doses
Report on results of dose-response analyses from case-control study

Report on results of doseresponse analyses from casecontrol study

Report on status of posting results in the study registry(s) for WP3

Report on status of posting results in the study registrys for WP3

MEDIRAD First Reommendations

MEDIRAD First Recommendations

Correlation analysis between objective and subjective image quality in chest CT patient parameter and indication dependent
Second Stakeholder Board annual report
Report on the organization and findings of the two seminars organized within Task 6.4

Report on the organization and findings of the two seminars organized within Task 64

Report on the Stakeholder Forum: composition, content of the web-consultation, guidelines for the use of the stakeholder infrastructure
Report on the use of the DNA damage assay to determine radiosensitivity in patients
Third Stakeholder Board annual report
Report on status of posting results in the study registry(s) for WP2
Report on system integration and publication of the basic user guidelines
Imaging and data collection study protocols
Report on results of the analyses of factors – environmental, genetic and epigenetic – that can modify risk of cancer following low doses of radiation from CT scanning in childhood and adolescence

Report on results of the analyses of factors environmental genetic and epigenetic that can modify risk of cancer following low doses of radiation from CT scanning in childhood and adolescence

European DRLs for specific applications of CT in multi-modality systems
Organ dose conversion coefficients for the estimation of patient doses from CT for attenuation correction and anatomic localization in multi-modality imaging
Report on results of the analysis of exomes and methylation
Report on validation of centres for imaging network
Protocol for a large scale epidemiological study
Report on effectiveness of protective devices for staff in interventional procedures
Report on results of extended follow-up of cohorts

Report on results of extended followup of cohorts

MEDIRAD Fourth Recommendations
Midterm recruitment report for WP3
Project website and visual identity

Project website and visual identity established and completed

First Stakeholder Board annual report

Dosimetry protocol and software
Implementation of the prototype of the central DICOM repository
Implementation and testing of the RDF repository
Biokinetic model for treatment planning
Accelerated Monte Carlo code for an on-line patient monitoring system in interventional cardiology procedures
Software tool (CT-IQURAD) module on image quality
Software tool (CT-IQURAD) module on radiation dose
Catalogue with Codes relevant for MEDIRAD project
Six segmented thorax phantoms

Publications

Efficacy of MAVIG X-Ray Protective Drapes in Reducing CTO Operator Radiation

Author(s): Keir McCutcheon, Maarten Vanhaverbeke, Jérémie Dabin, Ruben Pauwels, Werner Schoonjans, Walter Desmet, Johan Bennett
Published in: Journal of Interventional Cardiology, Issue 2021, 2021, ISSN 0896-4327
Publisher: Blackwell Publishing Inc.
DOI: 10.1155/2021/3146104

Validation of organ dose calculations with PyMCGPU-IR in realistic interventional set-ups

Author(s): David Fernández-Bosman, Ariel von Barnekow, Jérémie Dabin, Françoise Malchair, Filip Vanhavere, Maria Amor Duch, Mercè Ginjaume
Published in: Physica Medica, Issue 93, 2021, Page(s) 29-37, ISSN 1120-1797
Publisher: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.12.004

MEDIRAD formulation of science-based recommendations for medical radiation protection: a stakeholder forum survey

Author(s): M. Benderitter, E. Herrera Reyes, M.A. Benadjaoud, F. Vanhavere, N. Impens, U. Mayerhofer-Sebera, M. Hierath, J.R. Jourdain, G. Frija, J. Repussard
Published in: Radioprotection, Issue 56 / 4, 2021, Page(s) 275 - 285, ISSN 0033-8451
Publisher: EDP Sciences
DOI: 10.1051/radiopro/2021030

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

Author(s): Magy Sallam, Mohammed Abderrafi Benotmane, Sarah Baatout, Pieter-Jan Guns, An Aerts
Published in: Epigenetics, Issue 17 / 1, 2021, Page(s) 59-80, ISSN 1559-2308
Publisher: Taylor & Francis
DOI: 10.1080/15592294.2021.1873628

Penalized estimation of the Gaussian graphical model from data with replicates

Author(s): Wessel N. van Wieringen,Yao Chen
Published in: Statistics in Medicine, Issue 40 / 19, 2021, Page(s) 4279-4293, ISSN 1097-0258
Publisher: John Wiley & Sons Ltd
DOI: 10.1002/sim.9028

Evaluation of a suspended radiation protection system to reduce operator exposure in cardiology interventional procedures

Author(s): Federica Zanca PhD, Jérémie Dabin IR, Celine Collard DNP, Nicolas Alexandre IR, Alicia De Groote IR, Jean Paul Salembier MD, Michel Henry MD, Emmanuel Rombaut MD, Sonia Sghaier MD, Pierre-Emmanuel Massart MD
Published in: Catheterization and Cardiovascular Interventions, Issue 98 / 5, 2021, Page(s) E687-E694, ISSN 1522-726X
Publisher: John Wiley & Sons, Ltd.
DOI: 10.1002/ccd.29894

The effect of lead free cap on the doses of ionizing radiation to the head of interventional cardiologists working in haemodynamic room

Author(s): Włodzimierz Grabowicz, Konrad Masiarek, Tomasz Górnik, Tomasz Grycewicz, Marcin Brodecki, Jérémie Dabin, Christelle Huet, Filip Vanhavere, Joanna K. Domienik-Andrzejewska
Published in: International Journal of occupational medicine and environmental health, Issue 2022, 2022, ISSN 1232-1087
Publisher: Instytut Medycyny Pracy im. Jerzego Nofera/Nofer Institute of Occupational Medicine
DOI: 10.13075/ijomeh.1896.01958

VIEWDEX 3.0 - recent development of a software application facilitating assessment of image quality and observer performance

Author(s): Angelica Svalkvist, Sune Svensson, Tommy Hagberg, Magnus Båth
Published in: Radiation Protection Dosimetry, Issue 195 / 3-4, 2021, Page(s) 372–377, ISSN 1742-3406
Publisher: Oxford University Press
DOI: 10.1093/rpd/ncab014

Simulating the dynamics of atherosclerosis to the incidence of myocardial infarction, applied to the KORA population

Author(s): Cristoforo Simonetto, Susanne Rospleszcz, Margit Heier, Christa Meisinger, Annette Peters, Jan Christian Kaiser
Published in: Statistics in Medicine, Issue 40 / 14, 2021, Page(s) 3299-3312, ISSN 1097-0258
Publisher: John Wiley & Sons Ltd
DOI: 10.1002/sim.8951

Does deep inspiration breath-hold prolong life? Individual risk estimates of ischaemic heart disease after breast cancer radiotherapy

Author(s): Cristoforo Simonetto, Markus Eidemüller, Aurélie Gaasch, Montserrat Pazos, Stephan Schönecker, Daniel Reitz, Stefan Kääb, Michael Braun, Nadia Harbeck, Maximilian Niyazi, Claus Belka, Stefanie Corradini
Published in: Radiotherapy and Oncology, Issue 7 Aug 2018 (on-line publication), 2018, Page(s) Print not yet available, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2018.07.024

Automatic Tube Current Modulation and Tube Voltage Selection in Pediatric Computed Tomography

Author(s): Antonios E. Papadakis, John Damilakis
Published in: Investigative Radiology, Issue December 17, 2018 - Volume Publish Ahead of Print - Issue - p, 2019, Page(s) 1, ISSN 0020-9996
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rli.0000000000000537

Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer: Protocol for a European Multicenter Prospective Cohort Study (MEDIRAD EARLY HEART Study)

Author(s): Valentin Walker, Anne Crijns, Johannes Langendijk, Daan Spoor, Rozemarijn Vliegenthart, Stephanie E Combs, Michael Mayinger, Arantxa Eraso, Ferran Guedea, Manuela Fiuza, Susana Constantino, Radia Tamarat, Dominique Laurier, Jean Ferrières, Elie Mousseaux, Elisabeth Cardis, Sophie Jacob
Published in: JMIR Research Protocols, Issue 7/10, 2018, Page(s) e178, ISSN 1929-0748
Publisher: Journal of Medical Internet Research (JMIR) Publications
DOI: 10.2196/resprot.9906

Conference Program

Author(s): J. Damilakis
Published in: Medical Physics, Issue 45/6, 2018, Page(s) 2691-2794, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.12968

Clinical Trials in Radiology

Author(s): M.-O. Bernier, S. Jacob, A.P.G. Crijns, J.A. Langendijk, R. Vliegenhart, S.E. Combs, M. Mayinger, A. Eraso, F. Guedea, M. Fiuza, S. Constantino Rosa Santos, E. Mousseaux, E. Cardis, G. Frija
Published in: Insights into Imaging, Issue 9/S1, 2018, Page(s) 643-649, ISSN 1869-4101
Publisher: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/s13244-018-0625-2

342. “MEDIRAD – Implications of Medical Low Dose Radiation Exposure”: A European-funded project aims to enhance the protection of patients and health professionals from exposure to low dose medical radiation

Author(s): A. Palma, E. Cisbani, C. De Angelis, S. Della Monaca, V. Dini, S. Grande, A. Rosi
Published in: Physica Medica, Issue 56, 2018, Page(s) 268-269, ISSN 1120-1797
Publisher: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2018.04.351

Risk for cardiovascular events responds nonlinearly to carotid intima-media thickness in the KORA F4 study

Author(s): Cristoforo Simonetto, Margit Heier, Susanne Rospleszcz, Christa Meisinger, Cornelia Then, Jochen Seißler, Annette Peters, Jan Christian Kaiser
Published in: Atherosclerosis, Issue 296, 2020, Page(s) 32-39, ISSN 0021-9150
Publisher: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2020.01.013

OpenDose: open access resources for nuclear medicine dosimetry

Author(s): Maxime Chauvin, Damian Borys, Francesca Botta, Pawel Bzowski, Jérémie Dabin, Ana M Denis-Bacelar, Aurélie Desbrée, Nadia Falzone, Boon Quand Lee, Andrea Mairiani, Alessandra Malaroda, Gilles Mathieu, Erin McKay, Erick Mora-Ramirez, Andrew P Robinson, David Sarrut, Lara Struelens, Alex Vergara Gil, Manuel Bardiès
Published in: Journal of Nuclear Medicine, 2020, Page(s) jnumed.119.240366, ISSN 0161-5505
Publisher: Kexue Chubaneshe/Science Press
DOI: 10.2967/jnumed.119.240366

Radio-biologically motivated modeling of radiation risks of mortality from ischemic heart diseases in the Canadian fluoroscopy cohort study

Author(s): Helmut Schöllnberger, Jan Christian Kaiser, Markus Eidemüller, Lydia B. Zablotska
Published in: Radiation and Environmental Biophysics, Issue 59/1, 2020, Page(s) 63-78, ISSN 0301-634X
Publisher: Springer Verlag
DOI: 10.1007/s00411-019-00819-9

Standardised quantitative radioiodine SPECT/CT Imaging for multicentre dosimetry trials in molecular radiotherapy

Author(s): Rebecca A Gregory, Iain Murray, Jonathan Gear, Francesca Leek, Sarah Chittenden, Andrew Fenwick, Jill Wevrett, James Scuffham, Jill Tipping, Brian Murby, Steve Jeans, Martha Stuffins, Sofia Michopoulou, Matthew Guy, Darren Morgan, Aida Hallam, David Hall, Heather Polydor, Colin Brown, Gerry Gillen, Nathan Dickinson, Sarah Brown, Jonathan Wadsley, Glenn Flux
Published in: Physics in Medicine & Biology, Issue 64/24, 2019, Page(s) 245013, ISSN 1361-6560
Publisher: IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine
DOI: 10.1088/1361-6560/ab5b6c

A multicentric IT platform for storage and sharing of imaging-based radiation dosimetric data

Author(s): Joël Spaltenstein, Nicolas van Dooren, Gérôme Pasquier, Nicolas Roduit, Marine Brenet, Guillaume Pasquier, Bernard Gibaud, Peter Mildenberger, Osman Ratib
Published in: International Journal of Computer Assisted Radiology and Surgery, 2020, ISSN 1861-6410
Publisher: Springer Verlag
DOI: 10.1007/s11548-020-02179-y

A Hybrid Reporting Platform for Extended RadLex Coding Combining Structured Reporting Templates and Natural Language Processing

Author(s): Florian Jungmann, G. Arnhold, B. Kämpgen, T. Jorg, C. Düber, P. Mildenberger, R. Kloeckner
Published in: Journal of Digital Imaging, 2020, ISSN 0897-1889
Publisher: Springer Verlag
DOI: 10.1007/s10278-020-00342-0

When Stiffness Matters: Mechanosensing in Heart Development and Disease

Author(s): Roberto Gaetani, Eric Adriano Zizzi, Marco Agostino Deriu, Umberto Morbiducci, Maurizio Pesce, Elisa Messina
Published in: Frontiers in Cell and Developmental Biology, Issue 8, 2020, Page(s) Article 334, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.00334

Evaluation of an organ-based tube current modulation tool in pediatric CT examinations

Author(s): Antonios E. Papadakis, John Damilakis
Published in: European Radiology, 2020, ISSN 0938-7994
Publisher: Springer Verlag
DOI: 10.1007/s00330-020-06888-5

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma

Author(s): Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundrát, Steffi Pigorsch, Jan Christian Kaiser, Stephanie E. Combs
Published in: Radiation Oncology, Issue 15/1, 2020, ISSN 1748-717X
Publisher: BioMed Central
DOI: 10.1186/s13014-020-01541-3

Compartmental Model for 223Ra-Dichloride in Patients With Metastatic Bone Disease From Castration-Resistant Prostate Cancer

Author(s): Jan Taprogge, Iain Murray, Jonathan Gear, Sarah J. Chittenden, Christopher C. Parker, Glenn D. Flux
Published in: International Journal of Radiation Oncology*Biology*Physics, Issue 105/4, 2019, Page(s) 884-892, ISSN 0360-3016
Publisher: Elsevier BV
DOI: 10.1016/j.ijrobp.2019.07.022

DNA damage and repair in peripheral blood mononuclear cells after internal ex vivo irradiation of patient blood with 131I

Author(s): S. Schumann, H. Scherthan, K. Pfestroff, S. Schoof, A. Pfestroff, P. Hartrampf, N. Hasenauer, A. K. Buck, M. Luster, M. Port, M. Lassmann & U. Eberlein
Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue 49, 2022, Page(s) 1447-1455, ISSN 1619-7070
Publisher: Springer Verlag
DOI: 10.1007/s00259-021-05605-8

Occupational exposure to physicians working with a Zero-Gravity™ protection system in haemodynamic and electrophysiology labs and the assessment of its performance against a standard ceiling suspended shield

Author(s): Joanna Domienik-Andrzejewska, Mateusz Mirowski, Marek Jastrzębski, Tomasz Górnik, Konrad Masiarek, Izabela Warchoł & Włodzimierz Grabowicz
Published in: Radiation and Environmental Biophysics, Issue 61, 2022, Page(s) 293-300, ISSN 0301-634X
Publisher: Springer Verlag
DOI: 10.1007/s00411-022-00968-4

Setting up a quantitative SPECT imaging network for a European multi-centre dosimetry study of radioiodine treatment for thyroid cancer as part of the MEDIRAD project

Author(s): Jan Taprogge, Francesca Leek, Tino Schurrat, Johannes Tran-Gia, Delphine Vallot, Manuel Bardiès, Uta Eberlein, Michael Lassmann, Susanne Schlögl, Alex Vergara Gil, the MEDIRAD WP3 Investigator Team & Glenn D. Flux
Published in: EJNMMI Physics, Issue 7 / 61, 2020, ISSN 2197-7364
Publisher: Springer
DOI: 10.1186/s40658-020-00332-9

From atherosclerosis to myocardial infarction – a process-oriented model investigating the role of risk factors

Author(s): Cristoforo Simonetto, Margit Heier, Annette Peters, Jan Christian Kaiser, Susanne Rospleszcz Author Notes
Published in: American Journal of Epidemiology, Issue 2022, 2022, ISSN 0002-9262
Publisher: Oxford University Press
DOI: 10.1093/aje/kwac038

Generation of clinical 177Lu SPECT/CT images based on Monte Carlo simulation with GATE

Author(s): Gunjan Kayal, Maxime Chauvin, Alex Vergara-Gil, Naomi Clayton, Ludovic Ferrer, Tumelo Moalosi, Peter Knoll, Lara Struelens, Manuel Bardiès
Published in: Physica Medica, Issue 85, 2021, Page(s) 24-31, ISSN 1120-1797
Publisher: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.04.002

Modelling SPECT auto-contouring acquisitions for 177Lu & 131I molecular radiotherapy using new developments in Geant4/GATE

Author(s): Gunjan Kayal, Maxime Chauvin, Erick Mora-Ramirez, Naomi Clayton, Alex Vergara-Gil, Johannes Tran-Gia, Michael Lassmann, Nicholas Calvert, Jill Tipping, Lara Struelens, Manuel Bardiès
Published in: Physica Medica, Issue 96, 2022, Page(s) 101-113, ISSN 1120-1797
Publisher: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2022.03.003

Adjustment of the iodine ICRP population pharmacokinetic model for the use in thyroid cancer patients after thyroidectomy

Author(s): Jan Taprogge, Lily Carnegie-Peake, Iain Murray, Jonathan I Gear, Glenn D Flux
Published in: Journal of Radiological Protection, Issue 41 / 4, 2021, ISSN 0952-4746
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6498/ac149a

Building an Artificial Cardiac Microenvironment: A Focus on the Extracellular Matrix.

Author(s): Olivia Pagliarosi; Vittorio Picchio; Isotta Chimenti; Isotta Chimenti; Elisa Messina; Roberto Gaetani; Roberto Gaetani
Published in: Frontiers in Cell and Development Biology, Issue 12, 2020, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.559032

Efficacy of MAVIG X-Ray Protective Drapes in Reducing Operator Radiation Dose in the Cardiac Catheterization Laboratory

Author(s): Keir McCutcheon, Maarten Vanhaverbeke, Ruben Pauwels, Jérémie Dabin, Werner Schoonjans, Johan Bennett, Tom Adriaenssens, Christophe Dubois, Peter Sinnaeve and Walter Desmet
Published in: Circulation: Cardiovascular Interventions, Issue 13 / 11, 2020, ISSN 1941-7632
Publisher: American Heart Association
DOI: 10.1161/circinterventions.120.009627

Implications of Medical Low Dose Radiation Exposure (MEDIRAD)

Author(s): E. Cardis, G. Frija, EIBIR
Published in: European Congress of Radiology 2018 (EuroSafe Imaging poster exhibition), 2018
Publisher: European Society of Radiology
DOI: 10.1594/esi2018/esi-0080

MEDIRAD project “implications of medical low dose radiation exposure”: Enhancing the protection of patients and health professionals from exposure to low dose medical radiation

Author(s): S. Grande, A.Palma, E. Cisbani, C. De Angelis, S. Della Monaca, V. Dini, A. Rosi, on behalf of the MEDIRAD Consortium
Published in: "Il Nuovo Cimento (proceedings of ""XVIII Convegno Nazionale della Società Italiana per le Ricerche sulle Radiazioni"")", Issue IL NUOVO CIMENTO41 C(2018) 214, 2019
Publisher: Società Italiana di Fisica
DOI: 10.1393/ncc/i2018-18214-5

Image quality assessment of real patient thorax CT images using modulation transfer function and noise power spectrum

Author(s): Zahra Passand, Christoph Hoeschen
Published in: Medical Imaging 2020: Physics of Medical Imaging, 2020, Page(s) 94, ISBN 9781-510633926
Publisher: SPIE
DOI: 10.1117/12.2550073

Radiotherapy-induced cardiotoxicity in breast cancer patients: New approaches of early detection and prediction based on cardiac imaging and circulating biomarkers (European MEDIRAD EARLY-HEART study)

Author(s): V. Walker, S. Jacob, A. Crijns, J. Langendijk, D. Spoor, R. Vliegenthart, S. Combs, M. Mayinger, K. Borm, A. Eraso, F. Guedea, M. Fiuza, S. Constantino Rosa Santos, R. Tamarat, D. Laurier, J. Ferrières, E. Cardis, E. Mousseaux
Published in: Archives of Cardiovascular Diseases Supplements, Issue 11/1, 2019, Page(s) 124-125, ISSN 1878-6480
Publisher: Elsevier Masson
DOI: 10.1016/j.acvdsp.2018.10.275

Annual Congress of the European Association of Nuclear Medicine October 12 – 16, 2019 Barcelona, Spain

Author(s): F Leek, J Taprogge R Gregory, K Newbold, F Verburg, M Luster, T Schurrat, J Trans-Gia, U Eberlein, C Lapa, AK Buck, M Lassmann, E Mora-Ramirez, A Vergara-Gil, M Bardies, D Vallot, F Courbon, L Vija, G Flux
Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue 46/S1, 2019, Page(s) 1-952, ISSN 1619-7070
Publisher: Springer Verlag
DOI: 10.1007/s00259-019-04486-2

British Nuclear Medicine Society 47th Annual Spring Meeting, Oxford 1st–3rd April 2019

Author(s): J Taprogge et al: A population pharmacokinetic model for 131I-NaI therapy after thyroidectomy in thyroid cancer patients F Leek et al: The MEDIRAD multinational I-131 dosimetry study for thyroid ablation and adjuvant therapy
Published in: Nuclear Medicine Communications, Issue 40/4, 2019, Page(s) 393-453, ISSN 0143-3636
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mnm.0000000000000998

Biological effects of thoracic irradiation with low to moderate daily doses on rat lung

Author(s): Rocha, Filipe Nunes
Published in: Issue 2, 2019
Publisher: Universidade de Lisboa

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