Implications of Medical Low Dose Radiation Exposure

Resultado final

Report on optimisation of multi-modality imaging

Report on optimisation of multimodality imaging

Midterm recruitment report. Recruitment applies only to the nested case control study
Report on estimated doses for the case-control study subjects
Report on status of posting results in the study registry(s) for WP5

Report on status of posting results in the study registrys for WP5

Report on the current use of multi-modality systems in nuclear medicine
Update of administered activity-to-organ-dose conversion factors for two commonly used radiopharmaceuticals

Update of administered activitytoorgandose conversion factors for two commonly used radiopharmaceuticals

Report on results of the analysis miRNA and lncRNA
MEDIRAD Second Recommendations
Guidelines and recommendations for quantitative I-131 imaging and dosimetry
Midterm recruitment report for radiopharmaceutical dosimetry study
MEDIRAD Third Recommendations
Comprehensive Reporting Templates and Pilot system for SR-Reporting
Report on a) the organ dose data representation and b) collected organ doses
Report on results of dose-response analyses from case-control study

Report on results of doseresponse analyses from casecontrol study

Report on status of posting results in the study registry(s) for WP3

Report on status of posting results in the study registrys for WP3

MEDIRAD First Reommendations

MEDIRAD First Recommendations

Correlation analysis between objective and subjective image quality in chest CT patient parameter and indication dependent
Second Stakeholder Board annual report
Report on the organization and findings of the two seminars organized within Task 6.4

Report on the organization and findings of the two seminars organized within Task 64

Report on the Stakeholder Forum: composition, content of the web-consultation, guidelines for the use of the stakeholder infrastructure
Report on the use of the DNA damage assay to determine radiosensitivity in patients
Third Stakeholder Board annual report
Report on status of posting results in the study registry(s) for WP2
Report on system integration and publication of the basic user guidelines
Imaging and data collection study protocols
Report on results of the analyses of factors – environmental, genetic and epigenetic – that can modify risk of cancer following low doses of radiation from CT scanning in childhood and adolescence

Report on results of the analyses of factors environmental genetic and epigenetic that can modify risk of cancer following low doses of radiation from CT scanning in childhood and adolescence

European DRLs for specific applications of CT in multi-modality systems
Organ dose conversion coefficients for the estimation of patient doses from CT for attenuation correction and anatomic localization in multi-modality imaging
Report on results of the analysis of exomes and methylation
Report on validation of centres for imaging network
Protocol for a large scale epidemiological study
Report on effectiveness of protective devices for staff in interventional procedures
Report on results of extended follow-up of cohorts

Report on results of extended followup of cohorts

MEDIRAD Fourth Recommendations
Midterm recruitment report for WP3
Project website and visual identity

Project website and visual identity established and completed

First Stakeholder Board annual report

Dosimetry protocol and software
Implementation of the prototype of the central DICOM repository
Implementation and testing of the RDF repository
Biokinetic model for treatment planning
Accelerated Monte Carlo code for an on-line patient monitoring system in interventional cardiology procedures
Software tool (CT-IQURAD) module on image quality
Software tool (CT-IQURAD) module on radiation dose
Catalogue with Codes relevant for MEDIRAD project
Six segmented thorax phantoms

Publicaciones

Efficacy of MAVIG X-Ray Protective Drapes in Reducing CTO Operator Radiation

Autores: Keir McCutcheon, Maarten Vanhaverbeke, Jérémie Dabin, Ruben Pauwels, Werner Schoonjans, Walter Desmet, Johan Bennett
Publicado en: Journal of Interventional Cardiology, Edición 2021, 2021, ISSN 0896-4327
Editor: Blackwell Publishing Inc.
DOI: 10.1155/2021/3146104

Validation of organ dose calculations with PyMCGPU-IR in realistic interventional set-ups

Autores: David Fernández-Bosman, Ariel von Barnekow, Jérémie Dabin, Françoise Malchair, Filip Vanhavere, Maria Amor Duch, Mercè Ginjaume
Publicado en: Physica Medica, Edición 93, 2021, Página(s) 29-37, ISSN 1120-1797
Editor: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.12.004

MEDIRAD formulation of science-based recommendations for medical radiation protection: a stakeholder forum survey

Autores: M. Benderitter, E. Herrera Reyes, M.A. Benadjaoud, F. Vanhavere, N. Impens, U. Mayerhofer-Sebera, M. Hierath, J.R. Jourdain, G. Frija, J. Repussard
Publicado en: Radioprotection, Edición 56 / 4, 2021, Página(s) 275 - 285, ISSN 0033-8451
Editor: EDP Sciences
DOI: 10.1051/radiopro/2021030

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

Autores: Magy Sallam, Mohammed Abderrafi Benotmane, Sarah Baatout, Pieter-Jan Guns, An Aerts
Publicado en: Epigenetics, Edición 17 / 1, 2021, Página(s) 59-80, ISSN 1559-2308
Editor: Taylor & Francis
DOI: 10.1080/15592294.2021.1873628

Penalized estimation of the Gaussian graphical model from data with replicates

Autores: Wessel N. van Wieringen,Yao Chen
Publicado en: Statistics in Medicine, Edición 40 / 19, 2021, Página(s) 4279-4293, ISSN 1097-0258
Editor: John Wiley & Sons Ltd
DOI: 10.1002/sim.9028

Evaluation of a suspended radiation protection system to reduce operator exposure in cardiology interventional procedures

Autores: Federica Zanca PhD, Jérémie Dabin IR, Celine Collard DNP, Nicolas Alexandre IR, Alicia De Groote IR, Jean Paul Salembier MD, Michel Henry MD, Emmanuel Rombaut MD, Sonia Sghaier MD, Pierre-Emmanuel Massart MD
Publicado en: Catheterization and Cardiovascular Interventions, Edición 98 / 5, 2021, Página(s) E687-E694, ISSN 1522-726X
Editor: John Wiley & Sons, Ltd.
DOI: 10.1002/ccd.29894

The effect of lead free cap on the doses of ionizing radiation to the head of interventional cardiologists working in haemodynamic room

Autores: Włodzimierz Grabowicz, Konrad Masiarek, Tomasz Górnik, Tomasz Grycewicz, Marcin Brodecki, Jérémie Dabin, Christelle Huet, Filip Vanhavere, Joanna K. Domienik-Andrzejewska
Publicado en: International Journal of occupational medicine and environmental health, Edición 2022, 2022, ISSN 1232-1087
Editor: Instytut Medycyny Pracy im. Jerzego Nofera/Nofer Institute of Occupational Medicine
DOI: 10.13075/ijomeh.1896.01958

VIEWDEX 3.0 - recent development of a software application facilitating assessment of image quality and observer performance

Autores: Angelica Svalkvist, Sune Svensson, Tommy Hagberg, Magnus Båth
Publicado en: Radiation Protection Dosimetry, Edición 195 / 3-4, 2021, Página(s) 372–377, ISSN 1742-3406
Editor: Oxford University Press
DOI: 10.1093/rpd/ncab014

Simulating the dynamics of atherosclerosis to the incidence of myocardial infarction, applied to the KORA population

Autores: Cristoforo Simonetto, Susanne Rospleszcz, Margit Heier, Christa Meisinger, Annette Peters, Jan Christian Kaiser
Publicado en: Statistics in Medicine, Edición 40 / 14, 2021, Página(s) 3299-3312, ISSN 1097-0258
Editor: John Wiley & Sons Ltd
DOI: 10.1002/sim.8951

Does deep inspiration breath-hold prolong life? Individual risk estimates of ischaemic heart disease after breast cancer radiotherapy

Autores: Cristoforo Simonetto, Markus Eidemüller, Aurélie Gaasch, Montserrat Pazos, Stephan Schönecker, Daniel Reitz, Stefan Kääb, Michael Braun, Nadia Harbeck, Maximilian Niyazi, Claus Belka, Stefanie Corradini
Publicado en: Radiotherapy and Oncology, Edición 7 Aug 2018 (on-line publication), 2018, Página(s) Print not yet available, ISSN 0167-8140
Editor: Elsevier BV
DOI: 10.1016/j.radonc.2018.07.024

Automatic Tube Current Modulation and Tube Voltage Selection in Pediatric Computed Tomography

Autores: Antonios E. Papadakis, John Damilakis
Publicado en: Investigative Radiology, Edición December 17, 2018 - Volume Publish Ahead of Print - Edición - p, 2019, Página(s) 1, ISSN 0020-9996
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rli.0000000000000537

Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer: Protocol for a European Multicenter Prospective Cohort Study (MEDIRAD EARLY HEART Study)

Autores: Valentin Walker, Anne Crijns, Johannes Langendijk, Daan Spoor, Rozemarijn Vliegenthart, Stephanie E Combs, Michael Mayinger, Arantxa Eraso, Ferran Guedea, Manuela Fiuza, Susana Constantino, Radia Tamarat, Dominique Laurier, Jean Ferrières, Elie Mousseaux, Elisabeth Cardis, Sophie Jacob
Publicado en: JMIR Research Protocols, Edición 7/10, 2018, Página(s) e178, ISSN 1929-0748
Editor: Journal of Medical Internet Research (JMIR) Publications
DOI: 10.2196/resprot.9906

Conference Program

Autores: J. Damilakis
Publicado en: Medical Physics, Edición 45/6, 2018, Página(s) 2691-2794, ISSN 0094-2405
Editor: American Association of Physicists in Medicine
DOI: 10.1002/mp.12968

Clinical Trials in Radiology

Autores: M.-O. Bernier, S. Jacob, A.P.G. Crijns, J.A. Langendijk, R. Vliegenhart, S.E. Combs, M. Mayinger, A. Eraso, F. Guedea, M. Fiuza, S. Constantino Rosa Santos, E. Mousseaux, E. Cardis, G. Frija
Publicado en: Insights into Imaging, Edición 9/S1, 2018, Página(s) 643-649, ISSN 1869-4101
Editor: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/s13244-018-0625-2

342. “MEDIRAD – Implications of Medical Low Dose Radiation Exposure”: A European-funded project aims to enhance the protection of patients and health professionals from exposure to low dose medical radiation

Autores: A. Palma, E. Cisbani, C. De Angelis, S. Della Monaca, V. Dini, S. Grande, A. Rosi
Publicado en: Physica Medica, Edición 56, 2018, Página(s) 268-269, ISSN 1120-1797
Editor: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2018.04.351

Risk for cardiovascular events responds nonlinearly to carotid intima-media thickness in the KORA F4 study

Autores: Cristoforo Simonetto, Margit Heier, Susanne Rospleszcz, Christa Meisinger, Cornelia Then, Jochen Seißler, Annette Peters, Jan Christian Kaiser
Publicado en: Atherosclerosis, Edición 296, 2020, Página(s) 32-39, ISSN 0021-9150
Editor: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2020.01.013

OpenDose: open access resources for nuclear medicine dosimetry

Autores: Maxime Chauvin, Damian Borys, Francesca Botta, Pawel Bzowski, Jérémie Dabin, Ana M Denis-Bacelar, Aurélie Desbrée, Nadia Falzone, Boon Quand Lee, Andrea Mairiani, Alessandra Malaroda, Gilles Mathieu, Erin McKay, Erick Mora-Ramirez, Andrew P Robinson, David Sarrut, Lara Struelens, Alex Vergara Gil, Manuel Bardiès
Publicado en: Journal of Nuclear Medicine, 2020, Página(s) jnumed.119.240366, ISSN 0161-5505
Editor: Kexue Chubaneshe/Science Press
DOI: 10.2967/jnumed.119.240366

Radio-biologically motivated modeling of radiation risks of mortality from ischemic heart diseases in the Canadian fluoroscopy cohort study

Autores: Helmut Schöllnberger, Jan Christian Kaiser, Markus Eidemüller, Lydia B. Zablotska
Publicado en: Radiation and Environmental Biophysics, Edición 59/1, 2020, Página(s) 63-78, ISSN 0301-634X
Editor: Springer Verlag
DOI: 10.1007/s00411-019-00819-9

Standardised quantitative radioiodine SPECT/CT Imaging for multicentre dosimetry trials in molecular radiotherapy

Autores: Rebecca A Gregory, Iain Murray, Jonathan Gear, Francesca Leek, Sarah Chittenden, Andrew Fenwick, Jill Wevrett, James Scuffham, Jill Tipping, Brian Murby, Steve Jeans, Martha Stuffins, Sofia Michopoulou, Matthew Guy, Darren Morgan, Aida Hallam, David Hall, Heather Polydor, Colin Brown, Gerry Gillen, Nathan Dickinson, Sarah Brown, Jonathan Wadsley, Glenn Flux
Publicado en: Physics in Medicine & Biology, Edición 64/24, 2019, Página(s) 245013, ISSN 1361-6560
Editor: IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine
DOI: 10.1088/1361-6560/ab5b6c

A multicentric IT platform for storage and sharing of imaging-based radiation dosimetric data

Autores: Joël Spaltenstein, Nicolas van Dooren, Gérôme Pasquier, Nicolas Roduit, Marine Brenet, Guillaume Pasquier, Bernard Gibaud, Peter Mildenberger, Osman Ratib
Publicado en: International Journal of Computer Assisted Radiology and Surgery, 2020, ISSN 1861-6410
Editor: Springer Verlag
DOI: 10.1007/s11548-020-02179-y

A Hybrid Reporting Platform for Extended RadLex Coding Combining Structured Reporting Templates and Natural Language Processing

Autores: Florian Jungmann, G. Arnhold, B. Kämpgen, T. Jorg, C. Düber, P. Mildenberger, R. Kloeckner
Publicado en: Journal of Digital Imaging, 2020, ISSN 0897-1889
Editor: Springer Verlag
DOI: 10.1007/s10278-020-00342-0

When Stiffness Matters: Mechanosensing in Heart Development and Disease

Autores: Roberto Gaetani, Eric Adriano Zizzi, Marco Agostino Deriu, Umberto Morbiducci, Maurizio Pesce, Elisa Messina
Publicado en: Frontiers in Cell and Developmental Biology, Edición 8, 2020, Página(s) Article 334, ISSN 2296-634X
Editor: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.00334

Evaluation of an organ-based tube current modulation tool in pediatric CT examinations

Autores: Antonios E. Papadakis, John Damilakis
Publicado en: European Radiology, 2020, ISSN 0938-7994
Editor: Springer Verlag
DOI: 10.1007/s00330-020-06888-5

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma

Autores: Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundrát, Steffi Pigorsch, Jan Christian Kaiser, Stephanie E. Combs
Publicado en: Radiation Oncology, Edición 15/1, 2020, ISSN 1748-717X
Editor: BioMed Central
DOI: 10.1186/s13014-020-01541-3

Compartmental Model for 223Ra-Dichloride in Patients With Metastatic Bone Disease From Castration-Resistant Prostate Cancer

Autores: Jan Taprogge, Iain Murray, Jonathan Gear, Sarah J. Chittenden, Christopher C. Parker, Glenn D. Flux
Publicado en: International Journal of Radiation Oncology*Biology*Physics, Edición 105/4, 2019, Página(s) 884-892, ISSN 0360-3016
Editor: Elsevier BV
DOI: 10.1016/j.ijrobp.2019.07.022

DNA damage and repair in peripheral blood mononuclear cells after internal ex vivo irradiation of patient blood with 131I

Autores: S. Schumann, H. Scherthan, K. Pfestroff, S. Schoof, A. Pfestroff, P. Hartrampf, N. Hasenauer, A. K. Buck, M. Luster, M. Port, M. Lassmann & U. Eberlein
Publicado en: European Journal of Nuclear Medicine and Molecular Imaging, Edición 49, 2022, Página(s) 1447-1455, ISSN 1619-7070
Editor: Springer Verlag
DOI: 10.1007/s00259-021-05605-8

Occupational exposure to physicians working with a Zero-Gravity™ protection system in haemodynamic and electrophysiology labs and the assessment of its performance against a standard ceiling suspended shield

Autores: Joanna Domienik-Andrzejewska, Mateusz Mirowski, Marek Jastrzębski, Tomasz Górnik, Konrad Masiarek, Izabela Warchoł & Włodzimierz Grabowicz
Publicado en: Radiation and Environmental Biophysics, Edición 61, 2022, Página(s) 293-300, ISSN 0301-634X
Editor: Springer Verlag
DOI: 10.1007/s00411-022-00968-4

Setting up a quantitative SPECT imaging network for a European multi-centre dosimetry study of radioiodine treatment for thyroid cancer as part of the MEDIRAD project

Autores: Jan Taprogge, Francesca Leek, Tino Schurrat, Johannes Tran-Gia, Delphine Vallot, Manuel Bardiès, Uta Eberlein, Michael Lassmann, Susanne Schlögl, Alex Vergara Gil, the MEDIRAD WP3 Investigator Team & Glenn D. Flux
Publicado en: EJNMMI Physics, Edición 7 / 61, 2020, ISSN 2197-7364
Editor: Springer
DOI: 10.1186/s40658-020-00332-9

From atherosclerosis to myocardial infarction – a process-oriented model investigating the role of risk factors

Autores: Cristoforo Simonetto, Margit Heier, Annette Peters, Jan Christian Kaiser, Susanne Rospleszcz Author Notes
Publicado en: American Journal of Epidemiology, Edición 2022, 2022, ISSN 0002-9262
Editor: Oxford University Press
DOI: 10.1093/aje/kwac038

Generation of clinical 177Lu SPECT/CT images based on Monte Carlo simulation with GATE

Autores: Gunjan Kayal, Maxime Chauvin, Alex Vergara-Gil, Naomi Clayton, Ludovic Ferrer, Tumelo Moalosi, Peter Knoll, Lara Struelens, Manuel Bardiès
Publicado en: Physica Medica, Edición 85, 2021, Página(s) 24-31, ISSN 1120-1797
Editor: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.04.002

Modelling SPECT auto-contouring acquisitions for 177Lu & 131I molecular radiotherapy using new developments in Geant4/GATE

Autores: Gunjan Kayal, Maxime Chauvin, Erick Mora-Ramirez, Naomi Clayton, Alex Vergara-Gil, Johannes Tran-Gia, Michael Lassmann, Nicholas Calvert, Jill Tipping, Lara Struelens, Manuel Bardiès
Publicado en: Physica Medica, Edición 96, 2022, Página(s) 101-113, ISSN 1120-1797
Editor: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2022.03.003

Adjustment of the iodine ICRP population pharmacokinetic model for the use in thyroid cancer patients after thyroidectomy

Autores: Jan Taprogge, Lily Carnegie-Peake, Iain Murray, Jonathan I Gear, Glenn D Flux
Publicado en: Journal of Radiological Protection, Edición 41 / 4, 2021, ISSN 0952-4746
Editor: Institute of Physics Publishing
DOI: 10.1088/1361-6498/ac149a

Building an Artificial Cardiac Microenvironment: A Focus on the Extracellular Matrix.

Autores: Olivia Pagliarosi; Vittorio Picchio; Isotta Chimenti; Isotta Chimenti; Elisa Messina; Roberto Gaetani; Roberto Gaetani
Publicado en: Frontiers in Cell and Development Biology, Edición 12, 2020, ISSN 2296-634X
Editor: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.559032

Efficacy of MAVIG X-Ray Protective Drapes in Reducing Operator Radiation Dose in the Cardiac Catheterization Laboratory

Autores: Keir McCutcheon, Maarten Vanhaverbeke, Ruben Pauwels, Jérémie Dabin, Werner Schoonjans, Johan Bennett, Tom Adriaenssens, Christophe Dubois, Peter Sinnaeve and Walter Desmet
Publicado en: Circulation: Cardiovascular Interventions, Edición 13 / 11, 2020, ISSN 1941-7632
Editor: American Heart Association
DOI: 10.1161/circinterventions.120.009627

Implications of Medical Low Dose Radiation Exposure (MEDIRAD)

Autores: E. Cardis, G. Frija, EIBIR
Publicado en: European Congress of Radiology 2018 (EuroSafe Imaging poster exhibition), 2018
Editor: European Society of Radiology
DOI: 10.1594/esi2018/esi-0080

MEDIRAD project “implications of medical low dose radiation exposure”: Enhancing the protection of patients and health professionals from exposure to low dose medical radiation

Autores: S. Grande, A.Palma, E. Cisbani, C. De Angelis, S. Della Monaca, V. Dini, A. Rosi, on behalf of the MEDIRAD Consortium
Publicado en: "Il Nuovo Cimento (proceedings of ""XVIII Convegno Nazionale della Società Italiana per le Ricerche sulle Radiazioni"")", Edición IL NUOVO CIMENTO41 C(2018) 214, 2019
Editor: Società Italiana di Fisica
DOI: 10.1393/ncc/i2018-18214-5

Image quality assessment of real patient thorax CT images using modulation transfer function and noise power spectrum

Autores: Zahra Passand, Christoph Hoeschen
Publicado en: Medical Imaging 2020: Physics of Medical Imaging, 2020, Página(s) 94, ISBN 9781-510633926
Editor: SPIE
DOI: 10.1117/12.2550073

Radiotherapy-induced cardiotoxicity in breast cancer patients: New approaches of early detection and prediction based on cardiac imaging and circulating biomarkers (European MEDIRAD EARLY-HEART study)

Autores: V. Walker, S. Jacob, A. Crijns, J. Langendijk, D. Spoor, R. Vliegenthart, S. Combs, M. Mayinger, K. Borm, A. Eraso, F. Guedea, M. Fiuza, S. Constantino Rosa Santos, R. Tamarat, D. Laurier, J. Ferrières, E. Cardis, E. Mousseaux
Publicado en: Archives of Cardiovascular Diseases Supplements, Edición 11/1, 2019, Página(s) 124-125, ISSN 1878-6480
Editor: Elsevier Masson
DOI: 10.1016/j.acvdsp.2018.10.275

Annual Congress of the European Association of Nuclear Medicine October 12 – 16, 2019 Barcelona, Spain

Autores: F Leek, J Taprogge R Gregory, K Newbold, F Verburg, M Luster, T Schurrat, J Trans-Gia, U Eberlein, C Lapa, AK Buck, M Lassmann, E Mora-Ramirez, A Vergara-Gil, M Bardies, D Vallot, F Courbon, L Vija, G Flux
Publicado en: European Journal of Nuclear Medicine and Molecular Imaging, Edición 46/S1, 2019, Página(s) 1-952, ISSN 1619-7070
Editor: Springer Verlag
DOI: 10.1007/s00259-019-04486-2

British Nuclear Medicine Society 47th Annual Spring Meeting, Oxford 1st–3rd April 2019

Autores: J Taprogge et al: A population pharmacokinetic model for 131I-NaI therapy after thyroidectomy in thyroid cancer patients F Leek et al: The MEDIRAD multinational I-131 dosimetry study for thyroid ablation and adjuvant therapy
Publicado en: Nuclear Medicine Communications, Edición 40/4, 2019, Página(s) 393-453, ISSN 0143-3636
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mnm.0000000000000998

Biological effects of thoracic irradiation with low to moderate daily doses on rat lung

Autores: Rocha, Filipe Nunes
Publicado en: Edición 2, 2019
Editor: Universidade de Lisboa

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