Project description
Complex scientific training to fight complex pathologies like cardiorenal syndrome
Cardiorenal syndrome (CRS) are disorders of the heart, blood vessels, and kidneys, including cases of cardiovascular disease (CVD) in chronic kidney disease (CKD) patients. Funded by the Marie Skłodowska-Curie Actions programme, the CaReSyAn project aims to enhance the understanding, diagnostics, and therapy of CRS by training specialists to make them capable of using omics technologies, bioinformatics, and integrative analyses in their research. CaReSyAn will complement other European programs dedicated to CKD or CVD research and will leverage available patient cohorts, advanced technologies, and established cooperation. Fostering the development of broadly-trained scientists capable of bridging the gap between clinical and basic research is expected to significantly contribute to the fight against complex diseases such as CRS.
Objective
Successfully combatting a complex disease requires multi-disciplinary and methodically well-trained scientists. CaReSyAn strives to accomplish exactly this: we will train scientists to successfully integrate proteomics, clinical, experimental and bioinformatical analyses to enhance the understanding, diagnosis and therapy of the cardiorenal syndrome (CRS). CRS comprises disorders of the heart, vessels and kidneys, including the increased development of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). With ~45% of all deaths in CKD patients caused by CVD, the socio-economic burden of CRS is extremely high.
CaReSyAn will train scientists in a close cooperation between academia, SME and industry partners. Key objectives are to provide: 1) Excellent scientific training on CRS pathology, integrating clinical/mechanistic knowledge with technological skills (animals and in vitro, molecular and functional studies, proteomics and bioinformatics) to generate innovative insights triggering the understanding, diagnosis and treatment of the CRS; 2) Excellent complementary skills in personal and career development as well as business training required to extend beyond scientific research; and 3) Exposure to both academic and non-academic environments, required to build bridges between researchers and entrepreneurs and support the future translation of research findings in innovative products and services.
CaReSyAn builds on already available patient cohorts, advanced technologies and established cooperations. CaReSyAn is complementary to ongoing European programs focusing solely on CKD or CVD and strives to synergistically improve structural training on European level. CaReSyAn will nurture the development of young, broadly-trained scientists able to successfully bridge clinical with basic research as well as academia and industry. This is a cornerstone in effectively combatting complex diseases as CRS, a major killer of this century.
Fields of science
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomics
- social scienceseconomics and businessbusiness and managemententrepreneurship
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- medical and health sciencesbasic medicinepathology
- medical and health sciencesclinical medicinenephrologykidney diseases
Programme(s)
Funding Scheme
MSCA-ITN-ETN - European Training NetworksCoordinator
52074 Aachen
Germany