Descrizione del progetto
Una formazione scientifica sfaccettata per combattere patologie complesse come la sindrome cardiorenale
La sindrome cardiorenale (SCR) è una patologia che colpisco il cuore, i vasi sanguigni e i reni, e che include casi di malattie cardiovascolari (MCV) nei pazienti affetti da malattie renali croniche (MRC). Il progetto CaReSyAn, finanziato dal programma di azioni Marie Skłodowska-Curie, si prefigge di migliorare la comprensione, la diagnostica e la terapia della SCR attraverso la formazione di specialisti, affinché apprendano come utilizzare nella propria ricerca le tecnologie omiche, la bioinformatica e le analisi integrative. CaReSyAn completerà altri programmi europei dedicati alla ricerca sulle MCV o sulle MRC, e si avvarrà delle coorti di pazienti disponibili, delle tecnologie avanzate e dei modelli di cooperazione consolidati. Ci si attende che, favorendo la crescita professionale di scienziati con una formazione ampia, in grado di colmare il divario tra ricerca clinica e di base, si apporterà un contributo significativo alla lotta contro malattie complesse come la SCR.
Obiettivo
Successfully combatting a complex disease requires multi-disciplinary and methodically well-trained scientists. CaReSyAn strives to accomplish exactly this: we will train scientists to successfully integrate proteomics, clinical, experimental and bioinformatical analyses to enhance the understanding, diagnosis and therapy of the cardiorenal syndrome (CRS). CRS comprises disorders of the heart, vessels and kidneys, including the increased development of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). With ~45% of all deaths in CKD patients caused by CVD, the socio-economic burden of CRS is extremely high.
CaReSyAn will train scientists in a close cooperation between academia, SME and industry partners. Key objectives are to provide: 1) Excellent scientific training on CRS pathology, integrating clinical/mechanistic knowledge with technological skills (animals and in vitro, molecular and functional studies, proteomics and bioinformatics) to generate innovative insights triggering the understanding, diagnosis and treatment of the CRS; 2) Excellent complementary skills in personal and career development as well as business training required to extend beyond scientific research; and 3) Exposure to both academic and non-academic environments, required to build bridges between researchers and entrepreneurs and support the future translation of research findings in innovative products and services.
CaReSyAn builds on already available patient cohorts, advanced technologies and established cooperations. CaReSyAn is complementary to ongoing European programs focusing solely on CKD or CVD and strives to synergistically improve structural training on European level. CaReSyAn will nurture the development of young, broadly-trained scientists able to successfully bridge clinical with basic research as well as academia and industry. This is a cornerstone in effectively combatting complex diseases as CRS, a major killer of this century.
Campo scientifico
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomics
- social scienceseconomics and businessbusiness and managemententrepreneurship
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- medical and health sciencesbasic medicinepathology
- medical and health sciencesclinical medicinenephrologykidney diseases
Programma(i)
Argomento(i)
Meccanismo di finanziamento
MSCA-ITN-ETN - European Training NetworksCoordinatore
52074 Aachen
Germania