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Liver Spatial Omics

Publicaciones

Space-time logic of liver gene expression at sub-lobular scale

Autores: Colas Droin, Jakob El Kholtei, Keren Bahar Halpern, Clémence Hurni, Milena Rozenberg, Sapir Muvkadi, Shalev Itzkovitz, Felix Naef
Publicado en: Nature Metabolism, Issue 3/1, 2021, Page(s) 43-58, ISSN 2522-5812
Editor: Nature Metabolism
DOI: 10.1038/s42255-020-00323-1

Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Autores: Rita Manco The Weizmann Institute of Science, Department of Molecular Cell Biology Inna Averbukh The Weizmann Institute of Science, Department of Molecular Cell Biology Ziv Porat The Weizmann Institute of Science, Life Sciences Core Facilities Keren Bahar Halpern The Weizmann Institute of Science, Department of Molecular Cell Biology Ido Amit The Weizmann Institute of Science, Department of Sy
Publicado en: Nature communications, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-23245-2

Distal fecal wash host transcriptomics identifies inflammation throughout the colon and terminal ileum

Autores: Stav Dan The Weizmann Institute of Science, Department of Molecular Cell Biology Bella Ungar Tel Aviv University Shani Ben-Moshe The Weizmann Institute of Science, Department of Molecular Cell Biology Keren Bahar Halpern The Weizmann Institute of Science, Department of Molecular Cell Biology Miri Yavzori Tel Aviv University Ella Fudim Tel Aviv University Orit Picard Tel Aviv University Chay
Publicado en: Cellular and molecular gastroenterology and hepatology, 2023, ISSN 2352-345X
Editor: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2023.02.002

Zonation of Pancreatic Acinar Cells in Diabetic Mice

Autores: Adi Egozi, Keren Bahar Halpern, Lydia Farack, Hagar Rotem, Shalev Itzkovitz
Publicado en: Cell Reports, Issue 32/7, 2020, Page(s) 108043, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2020.108043

The spatiotemporal program of zonal liver regeneration following acute injury

Autores: Shani Ben-Moshe, Tamar Veg, Rita Manco, Stav Dan, Delfina Papinutti, Aviezer Lifshitz, Aleksandra A Kolodziejczyk, Keren Bahar Halpern, Eran Elinav and Shalev Itzkovitz
Publicado en: Cell stem cell, 2022, ISSN 1934-5909
Editor: Cell Press
DOI: 10.1016/j.stem.2022.04.008

Spatial discordances between mRNAs and proteins in the intestinal epithelium

Autores: Yotam Harnik, Lisa Buchauer, Shani Ben-Moshe, Inna Averbukh, Yishai Levin, Alon Savidor, Raya Eilam, Andreas E Moor and Shalev Itzkovitz
Publicado en: Nature metabolism, 2021, ISSN 2522-5812
Editor: Nature Research
DOI: 10.1038/s42255-021-00504-6

Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

Autores: Keren Bahar Halpern, Rom Shenhav, Hassan Massalha, Beata Toth, Adi Egozi, Efi E Massasa, Chiara Medgalia, Eyal David, Amir Giladi, Andreas E Moor, Ziv Porat, Ido Amit, Shalev Itzkovitz
Publicado en: Nature Biotechnology, Issue 36/10, 2018, Page(s) 962-970, ISSN 1087-0156
Editor: Nature Publishing Group
DOI: 10.1038/nbt.4231

Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis

Autores: Andreas E. Moor, Yotam Harnik, Shani Ben-Moshe, Efi E. Massasa, Milena Rozenberg, Raya Eilam, Keren Bahar Halpern, Shalev Itzkovitz
Publicado en: Cell, Issue 175/4, 2018, Page(s) 1156-1167.e15, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2018.08.063

Spatial sorting enables comprehensive characterization of liver zonation

Autores: Shani Ben-Moshe, Yonatan Shapira, Andreas E. Moor, Rita Manco, Tamar Veg, Keren Bahar Halpern, Shalev Itzkovitz
Publicado en: Nature Metabolism, Issue 1/9, 2019, Page(s) 899-911, ISSN 2522-5812
Editor: Nature Metabolism
DOI: 10.1038/s42255-019-0109-9

Lgr5+ telocytes are a signaling source at the intestinal villus tip

Autores: Keren Bahar Halpern, Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo-Azofeifa, Milena Rozenberg, Lydia Farack, Adi Egozi, Dan R. Miller, Inna Averbukh, Yotam Harnik, Noa Weinberg-Corem, Frederic J. de Sauvage, Ido Amit, Ophir D. Klein, Michal Shoshkes-Carmel, Shalev Itzkovitz
Publicado en: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-15714-x

Insulin is expressed by enteroendocrine cells during human fetal development

Autores: Adi Egozi, Dhana Llivichuzhca-Loja, Blake T McCourt, Keren Bahar Halpern, Lydia Farack, Xiaojing An, Fujing Wang, Kong Chen, Liza Konnikova and Shalev Itzkovitz
Publicado en: Nature medicine, 2021, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-021-01586-1

Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs.

Autores: Noam Cohen; Noam Cohen; Hassan Massalha; Hassan Massalha; Shani Ben-Moshe; Adi Egozi; Milena Rozenberg; Keren Bahar Halpern; Shalev Itzkovitz
Publicado en: PLoS Biology, Vol 19, Iss 10, p e3001214 (2021), Issue 2, 2021, ISSN 1544-9173
Editor: Public Library of Science
DOI: 10.1371/journal.pbio.3001214

Protocol for Single-Molecule Fluorescence In Situ Hybridization for Intact Pancreatic Tissue

Autores: Lydia Farack - The Weizmann Institute of Science, Department of Molecular Cell Biology Shalev Itzkovitz - The Weizmann Institute of Science, Department of Molecular Cell Biology
Publicado en: STAR protocols, 2020, ISSN 2666-1667
Editor: Elsevier
DOI: 10.1016/j.xpro.2019.100007

A single cell atlas of the human liver tumor microenvironment

Autores: Hassan Massalha, Keren Bahar Halpern, Samir Abu‐Gazala, Tamar Jana, Efi E Massasa, Andreas E Moor, Lisa Buchauer, Milena Rozenberg, Eli Pikarsky, Ido Amit, Gideon Zamir, Shalev Itzkovitz
Publicado en: Molecular Systems Biology, Issue 16/12, 2020, ISSN 1744-4292
Editor: Nature Publishing Group
DOI: 10.15252/msb.20209682

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