DiseasE-FreE social life without Antibiotics resisTance

Informazioni relative al progetto

DEFEAT

ID dell’accordo di sovvenzione: 771349

DOI

10.3030/771349

Progetto chiuso

Data della firma CE 24 Gennaio 2018

Data di avvio 1 Giugno 2018

Data di completamento 30 Novembre 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 998 809,00

Contributo UE

€ 1 998 809,00

Coordinato da

KOBENHAVNS UNIVERSITET
Denmark

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (28)

Isolation, characterisation and genome assembly of Barnettozyma botsteinii sp. nov. and novel strains of Kurtzmaniella quercitrusa isolated from the intestinal tract of the termite Macrotermes bellicosus.

Autori: Gerard Arrey; Guangshuo Li; Robert Murphy; Leandro Guimaraes; Sefa Alizadeh; Michael Poulsen; Birgitte Regenberg
Pubblicato in: G3: Genes, Genomes, Genetics, Numero Vol 11, Iss 12, 2021, Pagina/e jkab342, ISSN 2160-1836
Editore: Genetics Society of America
DOI: 10.1093/g3journal/jkab342

Disentangling the Relative Roles of Vertical Transmission, Subsequent Colonizations, and Diet on Cockroach Microbiome Assembly

Autori: Justinn Renelies-Hamilton, Kristjan Germer, David Sillam-Dussès, Kasun H. Bodawatta, Michael Poulsen
Pubblicato in: mSphere, Numero 6/1, 2021, Pagina/e e01023-20, ISSN 2379-5042
Editore: American Society for Microbiology Journals
DOI: 10.1128/msphere.01023-20

Adaptations of <i>Pseudoxylaria</i> towards a comb-associated lifestyle in fungus-farming termite colonies

Autori: Janis Fricke; Felix Schalk; Nina B Kreuzenbeck; Elena Seibel; Judith Hoffmann; Georg Dittmann; Benjamin H Conlon; Huijuan Guo; Z Wilhelm de Beer; Daniel Giddings Vassão; Gerd Gleixner; Michael Poulsen; Christine Beemelmanns
Pubblicato in: The ISME Journal, Numero 17, 2022, Pagina/e 733–747, ISSN 1751-7370
Editore: Nature Publishing Group
DOI: 10.1038/s41396-023-01374-4

The Termite Fungal Cultivar Termitomyces Combines Diverse Enzymes and Oxidative Reactions for Plant Biomass Conversion

Autori: Felix Schalk, Cene Gostinčar, Nina B. Kreuzenbeck, Benjamin H. Conlon, Elisabeth Sommerwerk, Patrick Rabe, Immo Burkhardt, Thomas Krüger, Olaf Kniemeyer, Axel A. Brakhage, Nina Gunde-Cimerman, Z. Wilhelm de Beer, Jeroen S. Dickschat, Michael Poulsen, Christine Beemelmanns
Pubblicato in: mBio, Numero 12/3, 2021, ISSN 2150-7511
Editore: ASM
DOI: 10.1128/mbio.03551-20

Comparative genomics unravels a rich set of biosynthetic gene clusters with distinct evolutionary trajectories across fungal species farmed by termites

Autori: Suzanne Schmidt, Robert Murphy, Joel Vizueta, Signe Schierbech, Benjamin Conlon, Nina Kreuzenbeck, Sabine Vreeburg, Lennart van de Peppel, Duur Aanen, Silue Kolotchèlèma, N'golo Kone, Christine Beemelmanns, Tilmann Weber, Michael Poulsen
Pubblicato in: Communications Biology, Numero 7, 2024, Pagina/e 1269, ISSN 2399-3642
Editore: Springer Nature
DOI: 10.21203/rs.3.rs-3921413/v1

Species- and Caste-Specific Gut Metabolomes in Fungus-Farming Termites

Autori: Kasun Bodawatta; Michael Poulsen; Suzanne Schmidt; Nanna Hjort Vidkjær; Christine Beemelmanns; Haofu Hu
Pubblicato in: Metabolites, Numero Volume 11; Numero 12, 2022, Pagina/e 839, ISSN 2218-1989
Editore: MDPI
DOI: 10.3390/metabo11120839

Female‐biased sex allocation and lack of inbreeding avoidance in Cubitermes termites

Autori: Veronica M. Sinotte, Benjamin H. Conlon, Elena Seibel, Jan W. Schwitalla, Z. Wilhelm de Beer, Michael Poulsen, Nick Bos
Pubblicato in: Ecology and Evolution, Numero 11/10, 2021, Pagina/e 5598-5605, ISSN 2045-7758
Editore: John Wiley and Sons Ltd
DOI: 10.1002/ece3.7462

Comparative Genomic and Metabolomic Analysis of <i>Termitomyces</i> Species Provides Insights into the Terpenome of the Fungal Cultivar and the Characteristic Odor of the Fungus Garden of <i>Macrotermes natalensis</i> Termites

Autori: Nina B. Kreuzenbeck; Elena Seibel; Jan W. Schwitalla; Janis Fricke; Benjamin H. Conlon; Suzanne Schmidt; Almuth Hammerbacher; Tobias G. Köllner; Michael Poulsen; Dirk Hoffmeister; Christine Beemelmanns
Pubblicato in: mSystems, Numero 7, 2022, Pagina/e e0121421, ISSN 2379-5077
Editore: ASM
DOI: 10.1128/msystems.01214-21

GNPS-guided discovery of xylacremolide C and D, evaluation of their putative biosynthetic origin and bioactivity studies of xylacremolide A and B

Autori: Felix Schalk, Janis Fricke, Soohyun Um, Benjamin H. Conlon, Hannah Maus, Nils Jäger, Thorsten Heinzel, Tanja Schirmeister, Michael Poulsen, Christine Beemelmanns
Pubblicato in: RSC Advances, Numero 11/31, 2021, Pagina/e 18748-18756, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/d1ra00997d

Disentangling the relative roles of vertical transmission, subsequent colonizations and diet on cockroach microbiome assembly

Autori: Justinn Renelies-Hamilton; Kristjan Germer; David Sillam-Dussès; Kasun H. Bodawatta; Michael Poulsen
Pubblicato in: mSphere, Numero 6, 2021, ISSN 2379-5042
Editore: American Society for Microbiology
DOI: 10.5281/zenodo.4074900

Disease-free monoculture farming by fungus-growing termites.

Autori: Saria Otani; Saria Otani; Victoria L. Challinor; Nina B. Kreuzenbeck; Sara Kildgaard; Søren Krath Christensen; Louise Lee Munk Larsen; Louise Lee Munk Larsen; Duur K. Aanen; Silas Anselm Rasmussen; Christine Beemelmanns; Michael Poulsen
Pubblicato in: Scientific Reports, Numero 9, 2019, Pagina/e 8819, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-45364-z

Make the environment protect you from disease: elevated CO2 inhibits antagonists of the fungus-farming termite symbiosis

Autori: Suzanne Schmidt; Nick Bos; Robert Murphy; N’Golo A. Koné; N’Golo A. Koné; Kolotchelema S. Silué; Kolotchelema S. Silué; Nicolai V. Meyling; Michael Poulsen
Pubblicato in: Frontiers in Ecology and Evolution, Numero 11, 2023, Pagina/e 1134492, ISSN 2296-701X
Editore: Frontiers
DOI: 10.3389/fevo.2023.1134492

Morphometrics, Distribution, and DNA Barcoding: An Integrative Identification Approach to the Genus Odontotermes (Termitidae: Blattodea) of Khyber Pakhtunkhwa, Pakistan

Autori: Maid Zaman; Imtiaz Ali Khan; Suzanne Schmidt; Robert Murphy; Michael Poulsen
Pubblicato in: MDPI Forests, Numero 13, 2022, Pagina/e 674, ISSN 1999-4907
Editore: MDPI Open Access Publishing
DOI: 10.3390/f13050674

Isolation, (bio)synthetic studies and evaluation of antimicrobial properties of drimenol-type sesquiterpenes of Termitomyces fungi

Autori: Nina B. Kreuzenbeck; Seema Dhiman; Dávid Roman; Immo Burkhardt; Benjamin H. Conlon; Janis Fricke; Huijuan Guo; Janis Blume; Helmar Görls; Michael Poulsen; Jeroen S. Dickschat; Tobias G. Köllner; Hans-Dieter Arndt; Christine Beemelmanns
Pubblicato in: Communications Chemistry, Numero 10, 2023, Pagina/e 79, ISSN 2399-3669
Editore: Nature
DOI: 10.1038/s42004-023-00871-z

Extensive inheritance of gut microbial communities in a superorganismal termite

Autori: Veronica Sinotte; Justinn Renelies-Hamilton; Sergio Andreu-Sánchez; Mireille Vasseur-Cognet; Michael Poulsen
Pubblicato in: Proceedings of the Royal Society of London B, Numero 290, 2023, Pagina/e 20231559, ISSN 1471-2954
Editore: Royal Society
DOI: 10.1098/rspb.2023.1559

Resistance and Vulnerability of Honeybee (Apis mellifera) Gut Bacteria to Commonly Used Pesticides

Autori: Ana Cuesta-Maté, Justinn Renelies-Hamilton, Per Kryger, Annette Bruun Jensen, Veronica M. Sinotte, Michael Poulsen
Pubblicato in: Frontiers in Microbiology, Numero 12, 2021, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2021.717990

Orthogonal protocols for DNA extraction from filamentous fungi

Autori: Jonathan Zvi Shik; Michael Poulsen; Suzanne Schmidt; Benjamin Conlon
Pubblicato in: STAR Protocols, Numero vol. 3 , no. 1, 2022, Pagina/e 101126, ISSN 2666-1667
Editore: Elsevier
DOI: 10.1016/j.xpro.2022.101126

Tripartite Symbiotic Digestion of Lignocellulose in the Digestive System of a Fungus-Growing Termite

Autori: Farhan Ahmad; Guiying Yang; Yaning Zhu; Michael Poulsen; Wuhan Li; Ting Yu; Jianchu Mo
Pubblicato in: mSpectrum, Numero Vol. 10, No. 6, 2022, Pagina/e 01234-22, ISSN 2165-0497
Editore: ASM
DOI: 10.1128/spectrum.01234-22

Foraging Macrotermes natalensis Fungus-Growing Termites Avoid a Mycopathogen but Not an Entomopathogen

Autori: Kasun Bodawatta, Michael Poulsen, Nick Bos
Pubblicato in: Insects, Numero 10/7, 2019, Pagina/e 185, ISSN 2075-4450
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/insects10070185

Synergies Between Division of Labor and Gut Microbiomes of Social Insects

Autori: Veronica M. Sinotte, Justinn Renelies-Hamilton, Benjamin A. Taylor, Kirsten M. Ellegaard, Panagiotis Sapountzis, Mireille Vasseur-Cognet, Michael Poulsen
Pubblicato in: Frontiers in Ecology and Evolution, Numero 7, 2020, ISSN 2296-701X
Editore: Frontiers
DOI: 10.3389/fevo.2019.00503

Comparative Genomic and Metabolic Analysis of Streptomyces sp. RB110 Morphotypes Illuminates Genomic Rearrangements and Formation of a New 46-Membered Antimicrobial Macrolide.

Autori: Soohyun Um; Huijuan Guo; Sirinthra Thiengmag; René Benndorf; Robert Murphy; Maja Rischer; Daniel F.O. Braga; Michael Poulsen; Z. Wilhelm de Beer; Gerald Lackner; Christine Beemelmanns
Pubblicato in: ACS chemical biology, Numero vol. 16 , no. 8, 2021, Pagina/e 1482-1492, ISSN 1554-8929
Editore: American Chemical Society
DOI: 10.1021/acschembio.1c00357

Avian gut microbiomes taking flight

Autori: Kasun H. Bodawatta; Sarah M. Hird; Kirsten Grond; Michael Poulsen; Knud A. Jønsson
Pubblicato in: Trends in Microbiology, Numero 30(3), 2022, Pagina/e 268-280, ISSN 0966-842X
Editore: Elsevier BV
DOI: 10.1016/j.tim.2021.07.003

You don’t have the guts: a diverse set of fungi survive passage through Macrotermes bellicosus termite guts

Autori: Nick Bos, Leandro Guimaraes, Romen Palenzuela, Justinn Renelies-Hamilton, Lorrie Maccario, Simon Kolotchèlèma Silue, N.’golo Abdoulaye Koné, Michael Poulsen
Pubblicato in: BMC Evolutionary Biology, Numero 20/1, 2020, ISSN 1471-2148
Editore: BioMed Central
DOI: 10.1186/s12862-020-01727-z

The chemical ecology of the fungus-farming termite symbiosis

Autori: Suzanne Schmidt, Sara Kildgaard, Huijuan Guo, Christine Beemelmanns, Michael Poulsen
Pubblicato in: Natural Product Reports, 2021, ISSN 0265-0568
Editore: Royal Society of Chemistry
DOI: 10.1039/d1np00022e

Comparative Genomics Reveals Prophylactic and Catabolic Capabilities of Actinobacteria within the Fungus-Farming Termite Symbiosis

Autori: Robert Murphy, René Benndorf, Z. Wilhelm de Beer, John Vollmers, Anne-Kristin Kaster, Christine Beemelmanns, Michael Poulsen
Pubblicato in: mSphere, Numero 6/2, 2021, ISSN 2379-5042
Editore: American Society for Microbiology
DOI: 10.1128/msphere.01233-20

RibDif2: expanding amplicon analysis to full genomes

Autori: Robert Murphy; Mikael Lenz Strube
Pubblicato in: Bioinformatics Advances, Numero 3, 2024, Pagina/e vbad111, ISSN 2635-0041
Editore: Oxford University Press
DOI: 10.1093/bioadv/vbad111

Shaping the tripartite symbiosis: are termite microbiome functions directed by the environmentally acquired fungal cultivar?

Autori: Robert Murphy, Veronica Sinotte, Ana Cuesta-Maté, Justinn Hamilton-Renelies, Mikael Lenz Strube, Michael Poulsen
Pubblicato in: Animal Microbiome, Numero 6, 2024, Pagina/e 44, ISSN 2524-4671
Editore: Springer Nature
DOI: 10.21203/rs.3.rs-3977060/v1

Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A

Autori: Elena Seibel, Soohyun Um, Marie Dayras, Kasun H. Bodawatta, Martinus de Kruijff, Knud A. Jønsson, Michael Poulsen, Ki Hyun Kim, Christine Beemelmanns
Pubblicato in: Communications Chemistry, Numero 6, 2023, ISSN 2399-3669
Editore: Springer Nature
DOI: 10.1038/s42004-023-01034-w

Other (1)

Learning from Nature: understanding sustainable antibiotic use

Autori: Michael Poulsen, Nick Bos, Sara Kildgaard
Pubblicato in: Health Europa, Numero 7, 2018, Pagina/e 176-179
Editore: Health Europa

Book chapters (1)

Impact of microbial symbionts on fungus-farming termites and their derived ecosystem functions

Autori: Robert Murphy, Veronica M. Sinotte, Suzanne Schmidt, Guangshuo Li, Justinn Renelies- Hamilton, N’Golo A. Koné and Michael Poulsen
Pubblicato in: Assessing the Microbiological Health of Ecosystems, 2022, Pagina/e 185-210, ISBN 9781119678328
Editore: Wiley
DOI: 10.1002/9781119678304.ch8