Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease

Project Information

DOUBLE EXPRESS

Grant agreement ID: 771419

DOI 10.3030/771419

EC signature date 15 May 2018

Start date 1 January 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 824 793,75

EU contribution € 1 824 793,75

Coordinated by

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Publications

Peer reviewed articles (5)

Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes

Author(s): Zoe Vance, Lukasz Niezabitowski, Laurence D Hurst, Aoife McLysaght
Published in: Genome Biology and Evolution, Issue 1, 2022, ISSN 1759-6653
Publisher: Oxford University Press
DOI: 10.1093/gbe/evac003

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

Author(s): Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24573-z

Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes

Author(s): Nikolaos Vakirlis, Anne-Ruxandra Carvunis, Aoife McLysaght
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.53500

Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding

Author(s): Anthony K. Redmond, Aoife McLysaght
Published in: Nature Communications, Issue 12/1, 2021, Page(s) 1-14, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22074-7

De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

Author(s): Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14500-z