Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease

Informations projet

DOUBLE EXPRESS

N° de convention de subvention: 771419

DOI 10.3030/771419

Date de signature de la CE 15 Mai 2018

Date de début 1 Janvier 2019

Date de fin 31 Decembre 2024

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total € 1 824 793,75

Contribution de l’UE € 1 824 793,75

Coordonné par

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Publications

Peer reviewed articles (5)

Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes

Auteurs: Zoe Vance, Lukasz Niezabitowski, Laurence D Hurst, Aoife McLysaght
Publié dans: Genome Biology and Evolution, Numéro 1, 2022, ISSN 1759-6653
Éditeur: Oxford University Press
DOI: 10.1093/gbe/evac003

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

Auteurs: Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh
Publié dans: Nature Communications, Numéro 12/1, 2021, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-24573-z

Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes

Auteurs: Nikolaos Vakirlis, Anne-Ruxandra Carvunis, Aoife McLysaght
Publié dans: eLife, Numéro 9, 2020, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.53500

Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding

Auteurs: Anthony K. Redmond, Aoife McLysaght
Publié dans: Nature Communications, Numéro 12/1, 2021, Page(s) 1-14, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-22074-7

De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

Auteurs: Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Publié dans: Nature Communications, Numéro 11/1, 2020, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-020-14500-z