Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease

Informazioni relative al progetto

DOUBLE EXPRESS

ID dell’accordo di sovvenzione: 771419

DOI 10.3030/771419

Data della firma CE 15 Maggio 2018

Data di avvio 1 Gennaio 2019

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 824 793,75

Contributo UE € 1 824 793,75

Coordinato da

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Pubblicazioni

Peer reviewed articles (5)

Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes

Autori: Zoe Vance, Lukasz Niezabitowski, Laurence D Hurst, Aoife McLysaght
Pubblicato in: Genome Biology and Evolution, Numero 1, 2022, ISSN 1759-6653
Editore: Oxford University Press
DOI: 10.1093/gbe/evac003

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

Autori: Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24573-z

Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes

Autori: Nikolaos Vakirlis, Anne-Ruxandra Carvunis, Aoife McLysaght
Pubblicato in: eLife, Numero 9, 2020, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.53500

Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding

Autori: Anthony K. Redmond, Aoife McLysaght
Pubblicato in: Nature Communications, Numero 12/1, 2021, Pagina/e 1-14, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-22074-7

De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

Autori: Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-14500-z