Computationally Active DNA Nanostructures

Projektinformationen

Active-DNA

ID Finanzhilfevereinbarung: 772766

DOI 10.3030/772766

EK-Unterschriftsdatum 2 Oktober 2018

Startdatum 1 November 2018

Enddatum 31 Oktober 2024

Finanziert unter

• EXCELLENT SCIENCE - European Research Council (ERC)

Gesamtkosten € 2 349 603,00

EU-Beitrag € 2 349 603,00

Koordiniert durch

NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
Ireland

Ziel

During the 20th century computer technology evolved from bulky, slow, special purpose mechanical engines to the now ubiquitous silicon chips and software that are one of the pinnacles of human ingenuity. The goal of the field of molecular programming is to take the next leap and build a new generation of matter-based computers using DNA, RNA and proteins. This will be accomplished by computer scientists, physicists and chemists designing molecules to execute ``wet'' nanoscale programs in test tubes. The workflow includes proposing theoretical models, mathematically proving their computational properties, physical modelling and implementation in the wet-lab.

The past decade has seen remarkable progress at building static 2D and 3D DNA nanostructures. However, unlike biological macromolecules and complexes that are built via specified self-assembly pathways, that execute robotic-like movements, and that undergo evolution, the activity of human-engineered nanostructures is severely limited. We will need sophisticated algorithmic ideas to build structures that rival active living systems. Active-DNA, aims to address this challenge by achieving a number of objectives on computation, DNA-based self-assembly and molecular robotics. Active-DNA research work will range from defining models and proving theorems that characterise the computational and expressive capabilities of such active programmable materials to experimental work implementing active DNA nanostructures in the wet-lab.

Wissenschaftliches Gebiet

• natural sciences › computer and information sciences › software
• natural sciences › biological sciences › genetics › DNA
• natural sciences › biological sciences › biochemistry › biomolecules › proteins
• natural sciences › biological sciences › genetics › RNA
• natural sciences › chemical sciences › inorganic chemistry › metalloids

Schlüsselbegriffe

• Molecular programming
• DNA computation
• DNA nanotechnology

Programm/Programme

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Thema/Themen

• ERC-2017-COG - ERC Consolidator Grant

Aufforderung zur Vorschlagseinreichung

ERC-2017-COG

Finanzierungsplan

ERC-COG - Consolidator Grant

Gastgebende Einrichtung

NATIONAL UNIVERSITY OF IRELAND MAYNOOTH

• Netto-EU-Beitrag: € 2 349 603,00
• Adresse: CO KILDARE ; W23 Maynooth ; Irland
• Region: Ireland › Eastern and Midland › Mid-East
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 2 349 603,00

Begünstigte (1)

NATIONAL UNIVERSITY OF IRELAND MAYNOOTH

Irland

• Netto-EU-Beitrag: € 2 349 603,00
• Adresse: CO KILDARE ; W23 Maynooth
• Region: Ireland › Eastern and Midland › Mid-East
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: € 2 349 603,00