Liver Investigation: Testing Marker Utility in Steatohepatitis

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Risk assessment procedure

Procedure for assessing risks and monitoring mitigation actions

Revised LITMUS Data Management Plan

Mid-term update of D2.2.

Final LITMUS Data Management Plan

Final version of DMP.

Detailed dissemination plan

Plans will be drawn up to regularly highlight the project developments at relevant conferences, in peer-reviewed journals and at dedicated workshops organised by the consortium. All journal publications will be open access. The dissemination plans, which will be continuously reviewed and updated, will identify key project related publications, which will be earmarked for “gold” open access. Dissemination will also be assured through the establishment and maintenance of a project website from the start of the project, with links to the participating researchers, clinicians and institutions.

Imaging manual to standardise image acquisition across all participating sites

LITMUS Imaging Manuals will be produced in parallel to the scanning protocol. One covering the MRI technical aspects and a second covering the ultrasound-based elastography technologies (using manufacturer protocols for VCTE, SSI, ARFI). These will be distributed to the participating sites to ensure standardised operating practices are followed across all participating sites.

Project Handbook

Quick reference guide for all LITMUS project participants

Mid-term report summarising recruitment into the LITMUS Registry and catalogue of available samples
SOPs for collection, processing and storage of whole blood, EDTA plasma, SST serum, urine, stool, frozen liver biopsies

Pre-analytical SOPs will be written covering, e.g. sample collection and analysis of the stability/quality of the metabolomics profile of serum/plasma samples.

Report describing minimally acceptable performance criteria for diagnostic testing

We will use Web-based surveys (SurveyMonkey) with all LITMUS participants to identify minimally acceptable performance criteria, using a modified Delphi approach over at least two rounds of surveys.

An optimised histological staging system for NAFLD-associated fibrosis

Development and validation of an optimised histological staging system for NAFLD-associated fibrosis with correlation to fibrosis severity measured by CPA.

Detailed plan for submission of biomarkers to the regulatory authorities (EMA and FDA) for qualification

Agreed project plan for LITMUS to secure an official description of the validation process from the agencies that studies engaging in biomarkers will need to follow and fulfil for biomarker qualification.

LITMUS Data Management Plan

This initial version of the DMP will describe the organisational and technical details about data collection, storage, retention, destruction, privacy and confidentiality. The Plan will also include details of the procedures for the transfer of data and will be accompanied by confirmation of compliance with national and EU law on the protection of individuals with regard to the processing of personal data.

Publications

Diagnostic accuracy of acoustic radiation force impulse elastography for the staging of hepatic fibrosis in non-alcoholic fatty liver disease: a systematic review and meta-analysis

Auteurs: E. Selvaraj, M. Zafarmand, F. Mozes, A. Jayaswal, C. Levick, N. Palaniyappan, C. Liu, S. Neubauer, S. Harrison, P. Bossuyt, Q. Anstee, M. Pavlides
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

High-throughput detection of novel circulating miRNA biomarkers of non-alcoholic fatty liver disease

Auteurs: Katherine Johnson, Peter J Leary, Matthew J Barter, Sarah H Charlton, Olivier Govaere, Simon J Cockell, Mattias Ekstedt, Karine Clément, Jörn M Schattenberg, Vlad Ratziu, Elisabetta Bugianesi, Ann K Daly, Quentin M Anstee
Publié dans: Hepatology, Numéro 70(S1), 2019
Éditeur: John Wiley & Sons, Inc.

Histological and biopsychosocial predictors of quality of life in Spanish and UK cohorts of patients with Non-Alcoholic Fatty Liver Disease

Auteurs: Jesús Funuyet-Salas, Agustín Martín-Rodríguez, María Angeles Pérez-San-Gregorio, Luke Vale, Tomos Robinson, Quentin M. Anstee, Manuel Romero Gomez, on behalf of the LITMUS consortium Investigators
Publié dans: Journal of Hepatology, Numéro 78(S1), 2023
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(23)01969-4

Interplay between metabolic derangement, biomarkers of collagen remodeling and macrophage activation in non-diabetic patients with non-alcoholic fatty liver disease

Auteurs: C. Rosso, R. Younes, D. Leeming, R. Surabattula, G.P. Caviglia, M. Gaggini, A. Armandi, A. Olivero, M.L. Abate, A. Gastaldelli, D. Schuppan, E. Bugianesi
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

Diagnostic accuracy of non-invasive tests for cirrhotic NASH – An individual participant data meta-analysis

Auteurs: F. E. Mózes, J. A. Lee, Y. Vali, E. A. Selvaraj, A. N. A.Jayaswal, J. Boursier, E. Bugianesi, R. Younes, M. Lupșor-Platon, S. Petta, T. Shima, T. Okanoue, S. Mahadeva, W-K. Chan, G. M. Hirschfield, P. J. Eddowes, P. N. Newsome, V. W.-S. Wong, V. de Lédinghen, J. F. Cobbold, Y. Sumida, A. Okajima, J. M. Schattenberg, C. Labenz, W. Kim, M. S. Lee, G. P. Aithal, N. Palaniyappan, C. Cassinotto, S.
Publié dans: Journal of Hepatology, Numéro 77(S1), 2022
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(22)01231-4

Determinants of liver stiffness measurements in patients with NAFLD – an individual patient data meta-analysis

Auteurs: F. E. Mózes, E. A. Selvaraj, A. N. A. Jayaswal, J. Boursier, C. Fournier, E. Bugianesi, R. Younes, S. Petta, S. Mahadeva, W.-K. Chan, P. J. Eddowes, P. N. Newsome, G. Hirschfield, V. W.-S. Wong, V. de Lédinghen, J. F. Cobbold, W. Kim, M. S. Lee, C. Cassinotto, G. Ooi, A. Nakajima, M. Yoneda, M.-H. Zheng, A. Geier, T. Tuthill, M. J. Brosnan, Q. M. Anstee, S. A. Harrison, P. M. Bossuyt, Michael Pa
Publié dans: Journal of Hepatology, Numéro 77(S1), 2022
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(22)01187-4

Diagnostic accuracy of magnetic resonance elastography for the staging of fibrosis and diagnosis of steatohepatitis in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis

Auteurs: F. Mozes, M. Zafarmand, A. Jayaswal, E. Selvaraj, C. Levick, N. Palaniyappan, C. Liu, S. Neubauer, Q. Anstee, S. Harrison, P. Bossuyt, M. Pavlides
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

Evaluating the patient-perceived impact of non-alcoholic steatohepatitis with compensated cirrhosis

Auteurs: M. Breckons, L.C. Doward, L. McSweeney, M-M. Balp, J. Twiss, Y. Oluboyede, L. Vale, L. Ternent, C.A. Brass, A.J. Sanyal, Q.M. Anstee
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

Patient-Reported Symptoms and Impact in Nonalcoholic Steatohepatitis: An Evaluation of the NASH-CHECK, a Novel PROM in NASH

Auteurs: D. Whalley, J. Twiss, L.C. Doward, M-M. Balp, C.A. Brass, J. Loeffler, P. Lopez, J. Cai, D. Cryer, Q.M. Anstee, A.J. Sanyal
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

In non obese NAFLD increased plasma saturated fatty acids and insulin resistance are metabolic signatures of severity of liver disease

Auteurs: F. Carli, M. Gaggini, C. Rosso, C. Saponaro, C. Barbieri, V.D. Latta, E. Buzzigoli, D. Ciociaro, M.L. Abate, M. Marietti, R. Younes, E. Bugianesi, A. Gastaldelli
Publié dans: Journal of Hepatology, Numéro 68, 2018, Page(s) S566, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/s0168-8278(18)31389-8

Predisposition to diabetes is related to insulin resistance in NAFLD patients and to decreased insulin secretion in HCV patients

Auteurs: G. Svegliati-Baroni, I. Pierantonelli, R. Younes, C. Rosso, C. Rychlicki, E. Bugianesi, A. Gastaldelli
Publié dans: Journal of Hepatology, Numéro 68, 2018, Page(s) S835, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/s0168-8278(18)31945-7

Selenoprotein P levels discriminate the degree of hepatic steatosis and are related to the NAS score in patients with non-alcoholic fatty liver disease

Auteurs: C. Rosso, R. Younes, E. Morello, M. Gaggini, G.P. Caviglia, C. Marinoni, M.J. Garcia Blanco, A. Olivero, G.M. Saracco, A. Gastaldelli, A. Smedile, E. Bugianesi
Publié dans: Digestive and Liver Disease, Numéro 51, 2019, Page(s) e26, ISSN 1590-8658
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.dld.2018.11.082

Accuracy of cytokeratin-18 (M30 and M65) in detecting NASH and fibrosis: a systematic review and meta-analysis

Auteurs: J. Lee, Y. Vali, Q. Anstee, K. Duffin, P. Bossuyt, M. Zafarmand
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

Insulin secretion is an independent predictor of hepatic ballooning in non-diabetic subjects with non-alcoholic fatty liver disease

Auteurs: R. YOUNES, C. ROSSO, G.P. CAVIGLIA, A. ARMANDI, A. OLIVERO, M.L. ABATE, E. BUGIANESI
Publié dans: Journal of Hepatology, Numéro 73(S1), 2020, Page(s) S401-S652
Éditeur: Elsevier B.V.

Establishing the Cut-offs and Confounding factors of Magnetic Resonance Elastography for staging NAFLD-fibrosis: an IPD meta-analysis

Auteurs: J. Liang, J. Ampuero, K. Imajo, M. Noureddin, J. Behari, D. H. Lee, R. L. Ehman, F. Rorsman, J. Vessby, J. R. Lacalle, F. Mozes, M. Pavlides, Q. M. Anstee, S. A. Harrison, J. Castell, R. Loomba, M. Romero Gómez
Publié dans: journal of Hepatology, Numéro 77(S1), 2022
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(22)01224-7

Diagnostic accuracy of non-invasive tests for fibrotic NASH – An individual participant data meta-analysis

Auteurs: F. E. Mózes, J. A. Lee, Y. Vali, E. A. Selvaraj, A. N. A. Jayaswal, J. Boursier, E. Bugianesi, R. Younes, M. Lupșor-Platon, S. Petta, T. Shima, T. Okanoue, S. Mahadeva, W-K. Chan, G. M. Hirschfield, P. J. Eddowes, P. N. Newsome, V. W.-S. Wong, V. de Lédinghen, J. F. Cobbold, Y. Sumida, A. Okajima, J. M. Schattenberg, C. Labenz, W. Kim, M. S. Lee, G. P. Aithal, N. Palaniyappan, C. Cassinotto, S.
Publié dans: Journal of Hepatology, Numéro 77(S1), 2022
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(22)01237-5

Signature of circulating hepatic proteins detects fibrosing steatohepatitis in progressive Non-alcoholic Fatty Liver Disease

Auteurs: Olivier Govaere, Megan Hasoon, Leigh Alexander, Simon Cockell, Dina Tiniakos, Jerome Boursier, Elisabetta Bugianesi, Vlad Ratziu, Ann Daly, Quentin M. Anstee
Publié dans: Journal of Hepatology, Numéro 77(S1), 2022
Éditeur: Elsevier Inc.
DOI: 10.1016/s0168-8278(22)01210-7

Clinicians’ Perspectives on Barriers and Facilitators for the Adoption of Non-Invasive Liver Tests for NAFLD: A Mixed-Method Study

Auteurs: Yasaman Vali, Roel Eijk, Timothy Hicks, William S. Jones Jana Suklan, Adriaan G. Holleboom, Vlad Ratziu, Miranda W. Langendam, Quentin M. Anstee, and Patrick M. M. Bossuyt, on behalf of the LITMUS Investigators
Publié dans: Journal of Clinical Medicine, Numéro 11(10), 2022, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11102707

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Auteurs: Ferenc E Mózes, Jenny A Lee, Yasaman Vali, Osama Alzoubi, Katharina Staufer, Michael Trauner, Rafael Paternostro, Rudolf E Stauber, Adriaan G Holleboom, Anne-Marieke van Dijk, Anne Linde Mak, Jérôme Boursier, Marc de Saint Loup, Toshihide Shima, Elisabetta Bugianesi, Silvia Gaia, Angelo Armandi, Shalimar, Monica Lupșor-Platon, Vincent Wai-Sun Wong, Guanlin Li, Grace Lai-Hung Wong, Jeremy Cobbo
Publié dans: Lancet Gastroenterology & Hepatology, Numéro 8(8), 2023, ISSN 2468-1253
Éditeur: Elsevier Ltd
DOI: 10.1016/s2468-1253(23)00141-3

Noninvasive assessment of liver disease severity in patients with nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes

Auteurs: Pennisi, Grazia; Enea, Marco; Falco, Vincenzo; Aithal, Guruprasad P.; Palaniyappan, Naaventhan; Yilmaz, Yusuf; Boursier, Jerome; Cassinotto, Christophe; de Lédinghen, Victor; Chan, Wah Kheong; Mahadeva, Sanjiv; Eddowes, Peter; Newsome, Philip; Karlas, Thomas; Wiegand, Johannes; Wong, Vincent Wai-Sun; Schattenberg, Jörn M.; Labenz, Christian; Kim, Won; Lee, Myoung Seok; Lupsor-Platon, Monica; Cob
Publié dans: Hepatology, Numéro 78(1), 2023, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
DOI: 10.1097/hep.0000000000000351

Insulin Resistance across the Spectrum of Nonalcoholic Fatty Liver Disease

Auteurs: Angelo Armandi; Chiara Rosso; Gian Paolo Caviglia; Elisabetta Bugianesi
Publié dans: Metabolites, Numéro 3, 2021, ISSN 2218-1989
Éditeur: MDPI
DOI: 10.3390/metabo11030155

FibroTest for Evaluating Fibrosis in Non-Alcoholic Fatty Liver Disease Patients: A Systematic Review and Meta-Analysis

Auteurs: Vali, Y., Lee, J., Boursier, J., Spijker, R., Verheij, J., Brosnan, M. J., Anstee, Q. M., Bossuyt, P. M., Zafarmand, M. H. and On Behalf Of The Litmus Systematic Review, Team
Publié dans: J Clin Med, Numéro 10(11), 2021, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10112415

Pathology and natural history of organ fibrosis

Auteurs: Joaquim Majo, Barbara Mara Klinkhammer, Peter Boor, Dina Tiniakos
Publié dans: Current Opinion in Pharmacology, Numéro 49, 2019, Page(s) 82-89, ISSN 1471-4892
Éditeur: Elsevier BV
DOI: 10.1016/j.coph.2019.09.009

Application of weighting methods for presenting risk-of-bias assessments in systematic reviews of diagnostic test accuracy studies

Auteurs: Yasaman Vali, Mariska M. G. Leeflang, Patrick M. M. Bossuyt
Publié dans: Systematic Reviews, Numéro 10, 2024, ISSN 2046-4053
Éditeur: BioMed Central
DOI: 10.1186/s13643-021-01744-z

From the origin of NASH to the future of metabolic fatty liver disease

Auteurs: Andreas Geier, Dina Tiniakos, Helmut Denk, Michael Trauner
Publié dans: Gut, Numéro 70(8), 2021, ISSN 0017-5749
Éditeur: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-323202

Metabolic signatures across the full spectrum of non-alcoholicfatty liver disease

Auteurs: Aidan J. McGlinchey, Olivier Govaere, Dawei Geng, Vlad Ratziu, Michael Allison, Jerome Boursier, Salvatore Petta, Claudia de Oliviera, Elisabetta Bugianesi, Jörn M. Schattenberg, Ann K. Daly, Tuulia Hyötyläinen, Quentin M. Anstee, Matej Oresic
Publié dans: JHEP Reports, Numéro 4(5), 2022, ISSN 2589-5559
Éditeur: Elsevier B.V.
DOI: 10.1016/j.jhepr.2022.100477

Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients

Auteurs: Antonio Gil-Gómez; Ángela Rojas; María R. García-Lozano; Rocío Muñoz-Hernández; Rocío Gallego-Durán; Douglas Maya-Miles; Rocío Montero-Vallejo; Sheila Gato; Javier Gallego; Rubén Francés; Germán Soriano; Javier Ampuero; Manuel Romero-Gómez
Publié dans: International Journal of Molecular Sciences, Numéro 23(19), 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911840

Accuracy of cytokeratin 18 (M30 and M65) in detecting non-alcoholic steatohepatitis and fibrosis: A systematic review and meta-analysis

Auteurs: Jenny Lee, Yasaman Vali, Jérôme Boursier, Kevin Duffin, Joanne Verheij, M. Julia Brosnan, Koos Zwinderman, Quentin M. Anstee, Patrick M. Bossuyt, Mohammad Hadi Zafarmand
Publié dans: PLOS ONE, Numéro 15/9, 2020, Page(s) e0238717, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0238717

Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

Auteurs: Judith Aron-Wisnewsky, Moritz V. Warmbrunn, Max Nieuwdorp, Karine Clément
Publié dans: Gastroenterology, Numéro 158/7, 2020, Page(s) 1881-1898, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.01.049

Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance

Auteurs: Katherine Johnson, Peter J. Leary, Olivier Govaere, Matthew J. Barter, Sarah H. Charlton, Simon J. Cockell, Dina Tiniakos, Michalina Zatorska, Pierre Bedossa, M. Julia Brosnan, Jeremy F. Cobbold, Mattias Ekstedt, Guruprasad P. Aithal, Karine Clément, Jörn M. Schattenberg, Jerome Boursier, Vlad Ratziu, Elisabetta Bugianesi, Quentin M. Anstee, Ann K. Daly
Publié dans: JHEP Reports, Numéro 4(2), 2022, ISSN 2589-5559
Éditeur: Elsevier B.V.
DOI: 10.1016/j.jhepr.2021.100409

Transcriptomic profiling across the Non-Alcoholic Fatty Liver Disease spectrum reveals gene signatures for steatohepatitis and fibrosis

Auteurs: Olivier Govaere, Simon Cockell, Dina Tiniakos, Rachel Queen, Ramy Younes, Michele Vacca, Leigh Alexander, Federico Ravaioli, Jeremy Palmer, Salvatore Petta, Jerome Boursier, Chiara Rosso, Katherine Johnson, Kristy Wonders, Christopher P. Day, Mattias Ekstedt, Matej Orešič, Rebecca Darlay, Heather J. Cordell, Fabio Marra, Antonio Vidal-Puig, Pierre Bedossa, Jörn M. Schattenberg, Karine Clément,
Publié dans: Science Translational Medicine, Numéro 12(572), 2020, ISSN 1946-6242
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aba4448

Prognostic accuracy of FIB‐4, NAFLD fibrosis score, and APRI for NAFLD‐related events: A systematic review

Auteurs: Jenny Lee, Yasaman Vali, Jerome Boursier, Rene Spijker, Quentin M. Anstee, Patrick M. Bossuyt, Mohammad H. Zafarmand
Publié dans: Liver International, Numéro 41(2), 2020, ISSN 1478-3231
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1111/liv.14669

Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period

Auteurs: Henning Hvid, Sara T. Hjuler, Pierre Bedossa, Dina G. Tiniakos, Ioannis Kamzolas, Lea M. Harder, Yaxin Xue, James W. Perfield, Rikke K. Kirk, Markus Latta, Lars F. Mikkelsen, Henrik D. Pedersen, null null
Publié dans: American Journal of Physiology-Gastrointestinal and Liver Physiology, Numéro 327, 2024, Page(s) G571-G585, ISSN 0193-1857
Éditeur: American Physiological Society
DOI: 10.1152/ajpgi.00120.2024

Systematic Review with Meta-Analysis: Diagnostic Accuracy of Pro-C3 for Hepatic Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease

Auteurs: Mak AL, Lee J, van Dijk A-M, Vali Y, Aithal GP, Schattenberg JM, Anstee QM, Brosnan MJ, Zafarmand MH, Ramsoekh D, Harrison SA, Nieuwdorp M, Bossuyt PM, Holleboom AG
Publié dans: Biomedicines, Numéro 9(12), 2021, Page(s) 1920, ISSN 2227-9059
Éditeur: MBPI
DOI: 10.3390/biomedicines9121920

Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD

Auteurs: Elizabeth M. Brunt, Andrew D. Clouston, Zachary Goodman, Cynthia Guy, David E. Kleiner, Carolin Lackner, Dina G. Tiniakos, Aileen Wee, Matthew Yeh, Wei Qiang Leow, Elaine Chng, Yayun Ren, George Goh Boon Bee, Elizabeth E. Powell, Mary Rinella, Arun J. Sanyal, Brent Neuschwander-Tetri, Zobair Younossi, Michael Charlton, Vlad Ratziu, Stephen A. Harrison, Dean Tai, Quentin M. Anstee
Publié dans: Journal of Hepatology, Numéro 76(5), 2022, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2022.01.011

Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease

Auteurs: Partho Sen Olivier Govaere, Tim Sinioja, Aidan McGlinchey, Dawei Geng, Vlad Ratziu, Elisabetta Bugianesi, Jörn M. Schattenberg, Antonio Vidal-Puig, Michael Allison, Simon Cockell, Ann K. Daly, Tuulia Hyötyläinen, Quentin M. Anstee, Matej Orešič
Publié dans: iScience, Numéro 25(9), 2022, ISSN 2589-0042
Éditeur: Elsevier B.V.
DOI: 10.1016/j.isci.2022.104949

Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank

Auteurs: Antonio De Vincentis, Federica Tavaglione, Rocco Spagnuolo, Roberta Pujia, Dario Tuccinardi, Gianluca Mascianà, Antonio Picardi, Raffaele Antonelli Incalzi, Luca Valenti, Stefano Romeo, Umberto Vespasiani-Gentilucci
Publié dans: International Journal of Obesity, Numéro 46, 2022, Page(s) 486-493, ISSN 0307-0565
Éditeur: Nature Publishing Group
DOI: 10.1038/s41366-021-01015-w

Machine learning algorithm improves detection of NASH (NAS-based) and at-risk NASH, a development and validation study

Auteurs: Lee, Jenny; Westphal, Max; Vali, Yasaman; Boursier, Jerome; Petta, Salvatorre; Ostroff, Rachel; Alexander, Leigh; Chen, Yu; Fournier, Celine; Geier, Andreas; Francque, Sven; Wonders, Kristy; Tiniakos, Dina; Bedossa, Pierre; Allison, Mike; Papatheodoridis, Georgios; Cortez-Pinto, Helena; Pais, Raluca; Dufour, Jean-Francois; Leeming, Diana Julie; Harrison, Stephen; Cobbold, Jeremy; Holleboom, Adriaa
Publié dans: Hepatology, Numéro 78(1), 2023, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
DOI: 10.1097/hep.0000000000000364

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue

Auteurs: Sami Qadri, Susanna Lallukka-Brück, Panu K. Luukkonen, You Zhou, Amalia Gastaldelli, Marju Orho-Melander, Henna Sammalkorpi, Anne Juuti, Anne K. Penttilä, Julia Perttilä, Antti Hakkarainen, Tiina E. Lehtimäki, Matej Orešič, Tuulia Hyötyläinen, Leanne Hodson, Vesa M. Olkkonen, Hannele Yki-Järvinen
Publié dans: Liver international, Numéro 40(9), 2020, ISSN 1478-3231
Éditeur: John Wiley & Sons, Inc
DOI: 10.1111/liv.14507

Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

Auteurs: Masoodi, M., Gastaldelli, A., Hyotylainen, T., Arretxe, E., Alonso, C., Gaggini, M., Brosnan, J., Anstee, Q. M., Millet, O., Ortiz, P., Mato, J. M., Dufour, J. F. and Oresic, M.
Publié dans: Nat Rev Gastroenterol Hepatol, 2021, ISSN 1759-5045
Éditeur: Nature Publishing Group
DOI: 10.1038/s41575-021-00502-9

Machine learning approaches to enhance diagnosis and staging of patients with MASLD using routinely available clinical information

Auteurs: Matthew McTeer, Douglas Applegate, Peter Mesenbrink, Vlad Ratziu, Jörn M. Schattenberg, Elisabetta Bugianesi, Andreas Geier, Manuel Romero Gomez, Jean-Francois Dufour, Mattias Ekstedt, Sven Francque, Hannele Yki-Jarvinen, Michael Allison, Luca Valenti, Luca Miele, Michael Pavlides, Jeremy Cobbold, Georgios Papatheodoridis, Adriaan G. Holleboom, Dina Tiniakos, Clifford Brass, Quentin M. Anstee, Pa
Publié dans: PLOS ONE, Numéro 19, 2024, Page(s) e0299487, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0299487

A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

Auteurs: Olivier Govaere, Megan Hasoon, Leigh Alexander, Simon Cockell, Dina Tiniakos, Mattias Ekstedt, Jörn M. Schattenberg, Jerome Boursier, Elisabetta Bugianesi, Vlad Ratziu, LITMUS Investigators, Ann K. Daly and Quentin M. Anstee
Publié dans: Nature Metabolism, Numéro 5, 2023, ISSN 2522-5812
Éditeur: Springer Nature Ltd
DOI: 10.1038/s42255-023-00775-1

Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

Auteurs: Govaere O, Petersen SK, Martinez-Lopez N, Wouters J, VanHaele M, Mancina RM, Jamialahmadi O, Bilkei-Gorzo O, Lassen PB, Darlay R, Peltier J, Palmer JM, Younes R, Tiniakos D, Aithal GP, Allison M, Vacca M, Göransson M, Berlinguer-Palmini R, Clark J, Drinnan MJ, Yki-Järvinen H, Dufour JF, Ekstedt M, Francque S, Petta S, Bugianesi E, Schattenberg JM, Day CP, Cordell HJ, Topal B, Clément K, Romeo S
Publié dans: Journal of Hepatology, 2021, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2021.12.012

Validation of NASH-CHECK: a novel patient-reported outcome measure for nonalcoholic steatohepatitis

Auteurs: James Twiss, Diane Whalley, Lynda Doward, Maria-Magdalena Balp, Clifford A. Brass, Donna Cryer, Arun Sanyal & Quentin M. Anstee
Publié dans: Journal of Patient-Reported Outcomes, Numéro 7, 2023, ISSN 2509-8020
Éditeur: Springer Nature
DOI: 10.1186/s41687-023-00589-5

Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study

Auteurs: Yasaman Vali, Jenny Lee, Jerome Boursier, Salvatore Petta, Kristy Wonders, Dina Tiniakos, Pierre Bedossa, Andreas Geier, Sven Francque, Mike Allison, Georgios Papatheodoridis, Helena Cortez-Pinto, Raluca Pais, Jean-Francois Dufour, Diana Julie Leeming, Stephen A Harrison, Yu Chen, Jeremy F Cobbold, Michael Pavlides, Adriaan G Holleboom, Hannele Yki-Jarvinen, Javier Crespo, Morten Karsdal, Rachel O
Publié dans: Lancet Gastroenterology & Hepatology, Numéro 8(8), 2023, ISSN 2468-1253
Éditeur: Elsevier Ltd
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Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17-beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms

Auteurs: Christian A. Hudert, Leon A. Adams, Anna Alisi, Quentin M. Anstee, Annalisa Crudele, Laura G. Draijer, EU-PNAFLD investigators, Samuel Furse, Jan G. Hengstler, Benjamin Jenkins, Kylie Karnebeek, Deirdre A. Kelly, Bart G. Koot, Albert Koulman, David Meierhofer, Phillip E. Melton, Trevor A. Mori, Stuart G. Snowden, Indra van Mourik, Anita Vreugdenhil, Susanna Wiegand, Jake P. Mann
Publié dans: Hepatology Communications, Numéro 6(8), 2022, ISSN 2471-254X
Éditeur: John Wiley & Sons Inc.
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Serum markers of type III and IV procollagen processing predict recurrence of fibrosis in liver transplanted patients

Auteurs: Mette Juul Nielsen, Ida Falk Villesen, Natasja Stæhr Gudmann, Diana Julie Leeming, Aleksander Krag, Morten Asser Karsdal, Tim Zimmermann, Detlef Schuppan
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-51394-4

Reporting of test comparisons in diagnostic accuracy studies: A literature review

Auteurs: Yasaman Vali, Bada Yang, Maria Olsen, Mariska M. G. Leeflang, Patrick M. Bossuyt
Publié dans: Research Synthesis Methods, Numéro 12(3), 2021, ISSN 1759-2887
Éditeur: John Wiley & Sons Ltd
DOI: 10.1002/jrsm.1469

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

Auteurs: Judith Aron-Wisnewsky, Chloé Vigliotti, Julia Witjes, Phuong Le, Adriaan G. Holleboom, Joanne Verheij, Max Nieuwdorp, Karine Clément
Publié dans: Nature Reviews Gastroenterology & Hepatology, Numéro 17/5, 2020, Page(s) 279-297, ISSN 1759-5045
Éditeur: Nature Publishing Group
DOI: 10.1038/s41575-020-0269-9

Is the Total Amount as Important as Localization and Type of Collagen in Liver Fibrosis Attributable to Steatohepatitis?

Auteurs: Morten A. Karsdal, Sönke Detlefsen, Samuel J. Daniels, Mette J. Nielsen, Aleksander Krag, Detlef Schuppan
Publié dans: Hepatology, Numéro 71/1, 2020, Page(s) 346-351, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/hep.30969

Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

Auteurs: Panu K. Luukkonen, Taru Tukiainen, Anne Juuti, Henna Sammalkorpi, P.A. Nidhina Haridas, Onni Niemelä, Johanna Arola, Marju Orho-Melander, Antti Hakkarainen, Petri T. Kovanen, Om Dwivedi, Leif Groop, Leanne Hodson, Amalia Gastaldelli, Tuulia Hyötyläinen, Matej Orešič, Hannele Yki-Järvinen
Publié dans: JCI Insight, Numéro 5/5, 2020, ISSN 2379-3708
Éditeur: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.132158

NASH in Lean Individuals

Auteurs: Ramy Younes, Elisabetta Bugianesi
Publié dans: Seminars in Liver Disease, Numéro 39/01, 2019, Page(s) 086-095, ISSN 0272-8087
Éditeur: Thieme Medical Publishers
DOI: 10.1055/s-0038-1677517

Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis

Auteurs: Geoff Farrell, Jörn M. Schattenberg, Isabelle Leclercq, Matthew M. Yeh, Robert Goldin, Narci Teoh, Detlef Schuppan
Publié dans: Hepatology, Numéro 69/5, 2019, Page(s) 2241-2257, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
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Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

Auteurs: Panu K. Luukkonen, Auli Nick, Maarit Hölttä-Vuori, Christoph Thiele, Elina Isokuortti, Susanna Lallukka-Brück, You Zhou, Antti Hakkarainen, Nina Lundbom, Markku Peltonen, Marju Orho-Melander, Matej Orešič, Tuulia Hyötyläinen, Leanne Hodson, Elina Ikonen, Hannele Yki-Järvinen
Publié dans: JCI Insight, Numéro 4/16, 2019, ISSN 2379-3708
Éditeur: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.127902

Auteurs: Lorraine McSweeney, Matthew Breckons, Gulnar Fattakhova, Yemi Oluboyede, Luke Vale, Laura Ternent, Maria-Magdalena Balp, Lynda Doward, Clifford A. Brass, Fiona Beyer, Arun Sanyal, Quentin M. Anstee
Publié dans: JHEP Reports, 2020, Page(s) 100099, ISSN 2589-5559
Éditeur: Elsevier Inc.
DOI: 10.1016/j.jhepr.2020.100099

PSD3 downregulation confers protection against fatty liver disease

Auteurs: Rosellina M. Mancina, Kavitha Sasidharan, Anna Lindblom, Ying Wei, Ester Ciociola, Oveis Jamialahmadi, Piero Pingitore, Anne-Christine Andréasson, Giovanni Pellegrini, Guido Baselli, Ville Männistö, Jussi Pihlajamäki, Vesa Kärjä, Stefania Grimaudo, Ilaria Marini, Marco Maggioni, Barbara Becattini, Federica Tavaglione, Carly Dix, Marie Castaldo, Stephanie Klein, Mark Perelis, Francois Pattou,
Publié dans: Nature Metabolism, Numéro 4, 2022, Page(s) 60-75, ISSN 2522-5812
Éditeur: Springer Nature Limited
DOI: 10.1038/s42255-021-00518-0

Systematic Review with Meta-Analyses: Diagnostic Accuracy of FibroMeter Tests in Patients with Non-Alcoholic Fatty Liver Disease

Auteurs: Van Dijk, A. M., Vali, Y., Mak, A. L., Lee, J., Tushuizen, M. E., Zafarmand, M. H., Anstee, Q. M., Brosnan, M. J., Nieuwdorp, M., Bossuyt, P. M. and Holleboom, A. G.
Publié dans: Journal of Clinical Medicine, 2021, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10132910

The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease

Auteurs: Timothy Hardy; Kristy Wonders; Ramy Younes; Guruprasad P. Aithal; Rocío Aller; Michael Allison; P. Bedossa; Fay Betsou; Jérôme Boursier; M. Julia Brosnan; Alastair Burt; Jeremy F.L. Cobbold; Helena Cortez-Pinto; Christopher Day; Jean-François Dufour; Mattias Ekstedt; Sven Francque; Seamus Conor Harrison; Luca Miele; Patrik Nasr; George V. Papatheodoridis; Salvatore Petta; Dina Tiniakos; Richar
Publié dans: Contemporary clinical trials, 98:106175, Numéro 9, 2020, ISSN 1551-7144
Éditeur: Elsevier BV
DOI: 10.1016/j.cct.2020.106175

An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography

Auteurs: Jia-xu Liang, Javier Ampuero, Hao Niu, Kento Imajo, Mazen Noureddin, Jaideep Behari, Dae Ho Lee, Richard L. Ehman, Fredrik Rorsman, Johan Vessby, Juan R. Lacalle, Ferenc E. Mózes, Michael Pavlides, Quentin M. Anstee, Stephen A. Harrison, Javier Castell, Rohit Loomba, Manuel Romero-Gómez on behalf of the LITMUS Consortium Investigators
Publié dans: Journal of Hepatology, Numéro 79(3), 2023, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2023.04.025

Protoporphyrin IX Binds to Iron(II)-Loaded and to Zinc-Loaded Human Frataxin

Auteurs: Ganeko Bernardo-Seisdedos, Andreas Schedlbauer, Tania Pereira-Ortuzar, José M. Mato and Oscar Millet
Publié dans: Life, Numéro 13(1), 2023, ISSN 2075-1729
Éditeur: MDPI
DOI: 10.3390/life13010222

Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic target

Auteurs: Cristiana Bianco, Elia Casirati, Francesco Malvestiti, Luca Valenti
Publié dans: JHEP Reports, Numéro 3(3), 2021, ISSN 2589-5559
Éditeur: Elsevier Inc.
DOI: 10.1016/j.jhepr.2021.100284

Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease

Auteurs: Nobuharu Tamaki, Noora Ahlholm, Panu K. Luukkonen, Kimmo Porthan, Suzanne R. Sharpton, Veeral Ajmera, Yuko Kono, Shravan Dave, Aijaz Ahmed, Vinay Sundaram, Michael J. Wilkinson, Heather Patton, Hersh Gupta, Vanessa Cervantes, Christie Hernandez, Scarlett J. Lopez, Ria Loomba, Amanda Baumgartner, Lisa Richards, Perttu E.T. Arkkila, Katriina Nemes, Helena Isoniemi, Hannele Yki-Järvinen and Rohit Lo
Publié dans: Journal of Clinical Investigation, Numéro 132(21), 2022, ISSN 0021-9738
Éditeur: American Society for Clinical Investigation
DOI: 10.1172/jci162513

Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk score

Auteurs: Cristiana Bianco, Oveis Jamialahmadi, Serena Pelusi, Guido Baselli,Paola Dongiovanni, Irene Zanoni, Luigi Santoro, Silvia Maier, Antonio Liguori, Marica Meroni, Vittorio Borroni, Roberta D’Ambrosio, Rocco Spagnuolo, Anna Alisi, Alessandro Federico, Elisabetta Bugianesi, Salvatore Petta, Luca Miele, Umberto Vespasiani-Gentilucci, Quentin M. Anstee, Felix Stickel, Jochen Hampe, Janett Fischer, Tho
Publié dans: Journal of Hepatology, Numéro 74(4), 2021, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2020.11.024

Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & validation of imaging modality performance across the NAFLD spectrum in a prospectively recruited cohort study (the LITMUS imaging study): Study protocol

Auteurs: Michael Pavlides, Ferenc E. Mozes, Salma Akhtar, Kristy Wonders, Jeremy Cobbold, Elizabeth M. Tunnicliffe, Michael Allison, Edmund M. Godfrey, Guruprasad P. Aithal, Susan Francis, Manuel Romero-Gomez, Javier Castell, Isabel Fernandez-Lizaranzu, Rocio Aller, Rebeca Sigüenza Gonzalez, Salvador Agustin, Juan M. Peric, Jerome Boursier, Christophe Aube, Vlad Ratziu, Mathilde Wagner, Salvatore Petta, M
Publié dans: Contemporary Clinical Trials, Numéro 134, 2023, ISSN 1551-7144
Éditeur: Elsevier BV
DOI: 10.1016/j.cct.2023.107352

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Auteurs: Elena Kotsiliti, Valentina Leone, Svenja Schuehle, Olivier Govaere, Hai Li, Monika J. Wolf, Helena Horvatic, Sandra Bierwirth, Jana Hundertmark, Donato Inverso, Laimdota Zizmare, Avital Sarusi-Portuguez, Revant Gupta, Tracy O’Connor, Anastasios D. Giannou, Ahmad Mustafa Shiri, Yehuda Schlesinger, Maria Garcia Beccaria, Charlotte Rennert, Dominik Pfister, Rupert Öllinger, Iana Gadjalova, Pierlui
Publié dans: Journal of Hepatology, Numéro 79, 2023, Page(s) 296-313, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2023.04.037

Lack of genetic evidence that fatty liver disease predisposes to COVID-19

Auteurs: Luca Valenti, Oveis Jamialahmadi, Stefano Romeo
Publié dans: Journal of Hepatology, Numéro 73/3, 2020, Page(s) 709-711, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2020.05.015

Derivation and validation of the nonalcoholic fatty liver disease cirrhosis score (NCS) to distinguish bridging fibrosis from cirrhosis

Auteurs: Christian Labenz, Gerrit Toenges, Ming-Hua Zheng, Dora Ding, Robert P. Myers, Peter R. Galle, Angelo Armandi, Javier Ampuero, Manuel Romero Gómez, Elisabetta Bugianesi, Quentin M. Anstee, Jörn M. Schattenberg
Publié dans: European Journal of Internal Medicine, Numéro 98, 2022, ISSN 0953-6205
Éditeur: Elsevier BV
DOI: 10.1016/j.ejim.2021.12.011

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

Auteurs: Ibon Martínez‐Arranz; Chiara Bruzzone; Mazen Noureddin; Ruben Gil‐Redondo; Itziar Mincholé; Maider Bizkarguenaga; Enara Arretxe; Marta Iruarrizaga‐Lejarreta; David Fernández‐Ramos; Fernando Lopitz‐Otsoa; Rebeca Mayo; Nieves Embade; Elizabeth Newberry; Bettina Mittendorf; Laura Izquierdo‐Sánchez; Vaclav Smid; Jorge Arnold; Paula Iruzubieta; Ylenia Pérez Castaño; Marcin Krawczyk; U
Publié dans: Hepatology, Numéro 76(4), 2022, ISSN 1527-3350
Éditeur: John Wiley & Sons, Inc.
DOI: 10.1002/hep.32427

Enhanced liver fibrosis test for the non-invasive diagnosis of fibrosis in patients with NAFLD: A systematic review and meta-analysis

Auteurs: Yasaman Vali, Jenny Lee, Jérôme Boursier, René Spijker, Jürgen Löffler, Joanne Verheij, M. Julia Brosnan, Zsolt Böcskei, Quentin M. Anstee, Patrick M. Bossuyt, Mohammad Hadi Zafarmand, Michael Pavlides, Christina Levick, Kevin Duffin, Craig Hyde, Tim Bauer, Pierre Bedossa, Diana Leeming, Ann Daly, Remy Hanf, Pablo Ortiz, Matej Oresic, Detlef Schuppan, Guido Hanauer, Yu Chen, Elizabeth Shumba
Publié dans: Journal of Hepatology, Numéro 73/2, 2020, Page(s) 252-262, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2020.03.036

Reply to: “Ceruloplasmin variants might have different effects in different iron overload disorders”

Auteurs: Elena Corradini; Luca Valenti
Publié dans: Crossref, Numéro 7, 2021, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2021.07.007

Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis

Auteurs: Mozes, F. E.; Lee, J. A.; Selvaraj, E. A.; Jayaswal, A. N. A.; Trauner, M.; Boursier, J.; Fournier, C.; Staufer, K.; Stauber, R. E.; Bugianesi, E.; Younes, R.; Gaia, S.; Lupsor-Platon, M.; Petta, S.; Shima, T.; Okanoue, T.; Mahadeva, S.; Chan, W. -K.; Eddowes, P. J.; Newsome, P. N.; Wong, V. W. -S.; de Ledinghen, V.; Fan, J.; Shen, F.; Cobbold, J. F.; Sumida, Y.; Okajima, A.; Schattenberg, J. M.;
Publié dans: "Gut, BMJ Publishing Group, 2021, pp.gutjnl-2021-324243. ⟨10.1136/gutjnl-2021-324243⟩", Numéro 2, 2021, ISSN 0017-5749
Éditeur: BMJ Publishing Group
DOI: 10.48350/160159

Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

Auteurs: Selvaraj, E. A., Mozes, F. E., Jayaswal, A. N. A., Zafarmand, M. H., Vali, Y., Lee, J. A., Levick, C. K., Young, L. A. J., Palaniyappan, N., Liu, C. H., Aithal, G. P., Romero-Gomez, M., Brosnan, M. J., Tuthill, T. A., Anstee, Q. M., Neubauer, S., Harrison, S. A., Bossuyt, P. M., Pavlides, M. and Investigators, Litmus
Publié dans: J Hepatol, Numéro 75(4), 2021, Page(s) 770-785, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/j.jhep.2021.04.044

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes

Auteurs: Marica Meroni, Paola Dongiovanni, Miriam Longo, Fabrizia Carli, Guido Baselli, Raffaela Rametta, Serena Pelusi, Sara Badiali, Marco Maggioni, Melania Gaggini, Anna Ludovica Fracanzani, Stefano Romeo, Stefano Gatti, Nicholas O. Davidson, Amalia Gastaldelli, Luca Valenti
Publié dans: EBioMedicine, Numéro 52, 2020, Page(s) 102658, ISSN 2352-3964
Éditeur: Elsevier BV
DOI: 10.1016/j.ebiom.2020.102658

Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?

Auteurs: Michael Pavlides, Ferenc E. Mózes, Stephen A. Harrison
Publié dans: Gut, Numéro 71, 2023, Page(s) 1453-1454, ISSN 0017-5749
Éditeur: BMJ Publishing Group
DOI: 10.1136/gutjnl-2021-326313

Differences between T1 and corrected T1 cannot be attributed to iron-correction only

Auteurs: Ferenc E. Mózes, Elizabeth M. Tunnicliffe
Publié dans: Pediatric Radiology, Numéro 51, 2021, Page(s) 499-500, ISSN 0301-0449
Éditeur: Springer Verlag
DOI: 10.1007/s00247-020-04956-y

MAFLD vs NAFLD: Let the contest begin!

Auteurs: Cristiana Bianco, Stefano Romeo, Salvatore Petta, Michelle T. Long, Luca Valenti
Publié dans: Liver International, Numéro 40/9, 2020, Page(s) 2079-2081, ISSN 1478-3223
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/liv.14620

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