Personalised maxillofacial bone regeneration

Informazioni relative al progetto

MAXIBONE

ID dell’accordo di sovvenzione: 779322

DOI

10.3030/779322

Progetto chiuso

Data della firma CE 27 Novembre 2017

Data di avvio 1 Gennaio 2018

Data di completamento 30 Giugno 2022

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 5 975 915,00

Contributo UE

€ 5 949 665,00

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (3)

Peer reviewed publication of the study in a high impact factor journal. Small animal study subcutis.

Title is selfdescribing additional details may be provided at request

Peer reviewed publication of the study in a high impact factor journal. Large animal study mandible

Title is self-describing, additional details may be provided at request

Peer reviewed publication of the study in a high impact factor journal. Small animal study mandibular critical size defect

Title is self-describing, additional details may be provided at request

Websites, patent fillings, videos etc. (1)

Website management : creation and update throughout the project

Please, refer to the WP4 description

Documents, reports (7)

Scientific Advisory Board reports

Four reports will be generated during the project the first one at M12 and then at M24 M36 and M54 due date indicated above

Completed recruitment and treatment delivery

Title is selfdescribing additional details may be provided at request

Develop a common clinical protocol for ethical committees and Medicine Agency submission

Includes investigator brochure, patient’s information sheets and consent forms in all languages from the participating centres.

Educational program for patients

A report will be generated twice during the project at M24 and at M48 due date indicated above

Outcomes of the recruitment by the different centres one year after the start of patient 1

To reassess the recruitment strategy in case of deviations from planning

Dissemination Committee reports

Four reports will be generated during the project the first one at M12 and then at M24 M36 and M54 due date indicated above

Educational programs associated with universities

Report on educational programs will be delivered at M24 for the first time and then repeated at M36 and M48 the due date indicated above

Other (1)

License for custom made medical device manufacturing

Title is selfdescribing additional details may be provided at request

Pubblicazioni

Peer reviewed articles (4)

Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells

Autori: Suliman S, Ali HRW, Karlsen TA, Amiaud J, Mohamed-Ahmed S, Layrolle P, Costea DE, Brinchmann JE, Mustafa K
Pubblicato in: Scientific Reports, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-52442-9

Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization

Autori: Rana N, Suliman S, Al-Sharabi N, Mustafa K
Pubblicato in: Cells, 2022, ISSN 2073-4409
Editore: MDP
DOI: 10.3390/cells11030470

Influence of Bone Substitutes on Mesenchymal Stromal Cells in an Inflammatory Microenvironment

Autori: Shanbhag S, Rana N, Suliman S, Idris SB, Mustafa K, Stavropoulos A.
Pubblicato in: Int J Mol Sci., 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24010438

A Comparative In Vitro and In Vivo Study of Osteogenicity by Using Two Biomaterials and Two Human Mesenchymal Stem Cell Subtypes

Autori: Fievet L, Serratrice N, Brulin B, Giraudo L, Véran J, Degardin N, Sabatier F, Féron F, Layrolle P.
Pubblicato in: Front. Cell Dev. Biol, 2022, ISSN 2296-634X
Editore: Frontiers
DOI: 10.3389/fcell.2022.913539