The PIDDosome in Centrosome and Ploidy-Surveillance

Publications

Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26

Auteurs: Matteo Burigotto, Alessia Mattivi, Daniele Migliorati, Giovanni Magnani, Chiara Valentini, Michela Roccuzzo, Martin Offterdinger, Massimo Pizzato, Alexander Schmidt, Andreas Villunger, Stefano Maffini, Luca L Fava
Publié dans: The EMBO Journal, Numéro 40/4, 2021, ISSN 0261-4189
Éditeur: Nature Publishing Group
DOI: 10.15252/embj.2020104844

PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis

Auteurs: Valentina C Sladky, Katja Knapp, Tamas G Szabo, Vincent Z Braun, Laura Bongiovanni, Hilda Bos, Diana CJ Spierings, Bart Westendorp, Ana Curinha, Tatjana Stojakovic, Hubert Scharnagl, Gerald Timelthaler, Kaoru Tsuchia, Matthias Pinter, Georg Semmler, Floris Foijer, Alain Bruin, Thomas Reiberger, Nataliya Rohr‐Udilova, Andreas Villunger
Publié dans: EMBO reports, Numéro 21/12, 2020, ISSN 1469-221X
Éditeur: Nature Publishing Group
DOI: 10.15252/embr.202050893

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

Auteurs: Valentina C. Sladky, Katja Knapp, Claudia Soratroi, Julia Heppke, Felix Eichin, Lourdes Rocamora-Reverte, Tamas G. Szabo, Laura Bongiovanni, Bart Westendorp, Eva Moreno, Elsbeth A. van Liere, Bjorn Bakker, Diana C.J. Spierings, René Wardenaar, David Pereyra, Patrick Starlinger, Simon Schultze, Michael Trauner, Tatjana Stojakovic, Hubert Scharnagl, Luca L. Fava, Floris Foijer, Alain de Bruin, Andr
Publié dans: Developmental Cell, Numéro 52/3, 2020, Page(s) 335-349.e7, ISSN 1534-5807
Éditeur: Cell Press
DOI: 10.1016/j.devcel.2019.12.016

Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

Auteurs: Valentina C. Sladky, Andreas Villunger
Publié dans: Cell Death & Differentiation, Numéro 12/12, 2020, ISSN 1350-9047
Éditeur: Nature Publishing Group
DOI: 10.1038/s41418-020-0556-6

Cell-Cycle Cross Talk with Caspases and Their Substrates

Auteurs: Patrick Connolly, Irmina Garcia-Carpio, Andreas Villunger
Publié dans: Cold Spring Harbor Perspectives in Biology, Numéro 12/6, 2020, Page(s) a036475, ISSN 1943-0264
Éditeur: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a036475

Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability

Auteurs: Taimoor I. Sheikh, Nasim Vasli, Stephen Pastore, Kimia Kharizi, Ricardo Harripaul, Zohreh Fattahi, Shruti Pande, Farooq Naeem, Abrar Hussain, Asif Mir, Omar Islam, Katta Mohan Girisha, Muhammad Irfan, Muhammad Ayub, Christoph Schwarzer, Hossein Najmabadi, Anju Shukla, Valentina C. Sladky, Vincent Zoran Braun, Irmina Garcia-Carpio, Andreas Villunger, John B. Vincent
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-020-01158-w

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