The PIDDosome in Centrosome and Ploidy-Surveillance

Pubblicazioni

Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26

Autori: Matteo Burigotto, Alessia Mattivi, Daniele Migliorati, Giovanni Magnani, Chiara Valentini, Michela Roccuzzo, Martin Offterdinger, Massimo Pizzato, Alexander Schmidt, Andreas Villunger, Stefano Maffini, Luca L Fava
Pubblicato in: The EMBO Journal, Numero 40/4, 2021, ISSN 0261-4189
Editore: Nature Publishing Group
DOI: 10.15252/embj.2020104844

PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis

Autori: Valentina C Sladky, Katja Knapp, Tamas G Szabo, Vincent Z Braun, Laura Bongiovanni, Hilda Bos, Diana CJ Spierings, Bart Westendorp, Ana Curinha, Tatjana Stojakovic, Hubert Scharnagl, Gerald Timelthaler, Kaoru Tsuchia, Matthias Pinter, Georg Semmler, Floris Foijer, Alain Bruin, Thomas Reiberger, Nataliya Rohr‐Udilova, Andreas Villunger
Pubblicato in: EMBO reports, Numero 21/12, 2020, ISSN 1469-221X
Editore: Nature Publishing Group
DOI: 10.15252/embr.202050893

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

Autori: Valentina C. Sladky, Katja Knapp, Claudia Soratroi, Julia Heppke, Felix Eichin, Lourdes Rocamora-Reverte, Tamas G. Szabo, Laura Bongiovanni, Bart Westendorp, Eva Moreno, Elsbeth A. van Liere, Bjorn Bakker, Diana C.J. Spierings, René Wardenaar, David Pereyra, Patrick Starlinger, Simon Schultze, Michael Trauner, Tatjana Stojakovic, Hubert Scharnagl, Luca L. Fava, Floris Foijer, Alain de Bruin, Andr
Pubblicato in: Developmental Cell, Numero 52/3, 2020, Pagina/e 335-349.e7, ISSN 1534-5807
Editore: Cell Press
DOI: 10.1016/j.devcel.2019.12.016

Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

Autori: Valentina C. Sladky, Andreas Villunger
Pubblicato in: Cell Death & Differentiation, Numero 12/12, 2020, ISSN 1350-9047
Editore: Nature Publishing Group
DOI: 10.1038/s41418-020-0556-6

Cell-Cycle Cross Talk with Caspases and Their Substrates

Autori: Patrick Connolly, Irmina Garcia-Carpio, Andreas Villunger
Pubblicato in: Cold Spring Harbor Perspectives in Biology, Numero 12/6, 2020, Pagina/e a036475, ISSN 1943-0264
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a036475

Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability

Autori: Taimoor I. Sheikh, Nasim Vasli, Stephen Pastore, Kimia Kharizi, Ricardo Harripaul, Zohreh Fattahi, Shruti Pande, Farooq Naeem, Abrar Hussain, Asif Mir, Omar Islam, Katta Mohan Girisha, Muhammad Irfan, Muhammad Ayub, Christoph Schwarzer, Hossein Najmabadi, Anju Shukla, Valentina C. Sladky, Vincent Zoran Braun, Irmina Garcia-Carpio, Andreas Villunger, John B. Vincent
Pubblicato in: Translational Psychiatry, Numero 11/1, 2021, ISSN 2158-3188
Editore: Nature Publishing Group
DOI: 10.1038/s41398-020-01158-w

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