The PIDDosome in Centrosome and Ploidy-Surveillance

Publicaciones

Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26

Autores: Matteo Burigotto, Alessia Mattivi, Daniele Migliorati, Giovanni Magnani, Chiara Valentini, Michela Roccuzzo, Martin Offterdinger, Massimo Pizzato, Alexander Schmidt, Andreas Villunger, Stefano Maffini, Luca L Fava
Publicado en: The EMBO Journal, Edición 40/4, 2021, ISSN 0261-4189
Editor: Nature Publishing Group
DOI: 10.15252/embj.2020104844

PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis

Autores: Valentina C Sladky, Katja Knapp, Tamas G Szabo, Vincent Z Braun, Laura Bongiovanni, Hilda Bos, Diana CJ Spierings, Bart Westendorp, Ana Curinha, Tatjana Stojakovic, Hubert Scharnagl, Gerald Timelthaler, Kaoru Tsuchia, Matthias Pinter, Georg Semmler, Floris Foijer, Alain Bruin, Thomas Reiberger, Nataliya Rohr‐Udilova, Andreas Villunger
Publicado en: EMBO reports, Edición 21/12, 2020, ISSN 1469-221X
Editor: Nature Publishing Group
DOI: 10.15252/embr.202050893

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

Autores: Valentina C. Sladky, Katja Knapp, Claudia Soratroi, Julia Heppke, Felix Eichin, Lourdes Rocamora-Reverte, Tamas G. Szabo, Laura Bongiovanni, Bart Westendorp, Eva Moreno, Elsbeth A. van Liere, Bjorn Bakker, Diana C.J. Spierings, René Wardenaar, David Pereyra, Patrick Starlinger, Simon Schultze, Michael Trauner, Tatjana Stojakovic, Hubert Scharnagl, Luca L. Fava, Floris Foijer, Alain de Bruin, Andr
Publicado en: Developmental Cell, Edición 52/3, 2020, Página(s) 335-349.e7, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2019.12.016

Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

Autores: Valentina C. Sladky, Andreas Villunger
Publicado en: Cell Death & Differentiation, Edición 12/12, 2020, ISSN 1350-9047
Editor: Nature Publishing Group
DOI: 10.1038/s41418-020-0556-6

Cell-Cycle Cross Talk with Caspases and Their Substrates

Autores: Patrick Connolly, Irmina Garcia-Carpio, Andreas Villunger
Publicado en: Cold Spring Harbor Perspectives in Biology, Edición 12/6, 2020, Página(s) a036475, ISSN 1943-0264
Editor: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a036475

Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability

Autores: Taimoor I. Sheikh, Nasim Vasli, Stephen Pastore, Kimia Kharizi, Ricardo Harripaul, Zohreh Fattahi, Shruti Pande, Farooq Naeem, Abrar Hussain, Asif Mir, Omar Islam, Katta Mohan Girisha, Muhammad Irfan, Muhammad Ayub, Christoph Schwarzer, Hossein Najmabadi, Anju Shukla, Valentina C. Sladky, Vincent Zoran Braun, Irmina Garcia-Carpio, Andreas Villunger, John B. Vincent
Publicado en: Translational Psychiatry, Edición 11/1, 2021, ISSN 2158-3188
Editor: Nature Publishing Group
DOI: 10.1038/s41398-020-01158-w

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