Advancing knowledge to improve outcome in Paget’s disease of bone

Project Information

Paget-Advance

Grant agreement ID: 787270

DOI

10.3030/787270

Project closed

EC signature date 19 June 2018

Start date 1 August 2018

End date 31 July 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 422 623,00

EU contribution

€ 2 422 623,00

Coordinated by

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data management plan

Data management

Publications

Peer reviewed articles (13)

Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status.

Author(s): Ilhame Diboun; Sachin Wani; Stuart H. Ralston; Omar M. E. Albagha; Omar M. E. Albagha
Published in: eLife, Issue 10/e65715, 2021, Page(s) 1-19, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65715

Bisphosphonates in the management of Paget's disease

Author(s): Ralston, SH
Published in: Bone, Issue 138, 2020, Page(s) 1-11, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2020.115465

Rare Inherited forms of Paget’s Disease and Related Syndromes

Author(s): Stuart H. Ralston, J. Paul Taylor
Published in: Calcified Tissue International, Issue 104/5, 2019, Page(s) 501-516, ISSN 0171-967X
Publisher: Springer Verlag
DOI: 10.1007/s00223-019-00520-5

Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort

Author(s): Owen Cronin, Deepak Subedi, Laura Forsyth, Kirsteen Goodman, Steff C Lewis, Catriona Keerie, Allan Walker, Mary Porteous, Roseanne Cetnarskyj, Lakshminarayan R Ranganath, Peter L Selby, Geeta Hampson, Rama Chandra, Shu Ho, Jon H Tobias, Steven A Young‐Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan Tang, Luigi Gennari, Rannuccio Nuti, Maria‐Luisa Brandi, Javier Pino‐Mont
Published in: Journal of Bone and Mineral Research, Issue 35/7, 2020, Page(s) 1246-1252, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4007

Causes of Musculoskeletal Pain in Paget’s Disease of Bone

Author(s): Kathryn Berg, Dervil Dockrell, Lesley Colvin, William D Fraser, Jonathan CY Tang, Terry Aspray, Elaine Dennison, Hrushikesh Divyateja, Nazim Ghouri, Esther Hanison, Richard Keen, Eugene McCloskey, Terence W O’Neill, Faizanur Rahman, Mashood Siddiqi, Stephen Tuck, Jane Turton, Stuart H Ralston
Published in: Calcified Tissue International, 2024, ISSN 1432-0827
Publisher: Springer Nature
DOI: 10.1007/s00223-024-01279-0

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget's Disease of Bone

Author(s): Diboun I, Wani S, Ralston SH, Albagha OME
Published in: Frontiers in Cell and Developmental Biology, 2022, Page(s) 903612, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2022.903612

Genetic Determinants of Paget’s Disease of Bone

Author(s): Navnit Makaram; Stuart H. Ralston
Published in: Makaram , N & Ralston , S H 2021 , ' Genetic determinants of Paget’s Disease of Bone ' , Current osteoporosis reports . https://doi.org/10.1007/s11914-021-00676-w, Issue 19, 2021, Page(s) 327-332, ISSN 1544-2241
Publisher: Springer-Nature
DOI: 10.1007/s11914-021-00676-w

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Author(s): Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Luigi Gennari, Núria Guañabens, M Kassim Javaid, Robert Layfield, Terence W O'Neill, R Graham G Russell, Michael D Stone, Keith Simpson, Diana Wilkinson, Ruth Wills, M Carola Zillikens, Stephen P Tuck
Published in: Journal of Bone and Mineral Research, Issue 34/4, 2019, Page(s) e3657, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3657

Paget’s disease of bone: when and why to refer to specialist care

Author(s): Catherine Nairn, Stuart H Ralston
Published in: British Journal of General Practice, Issue 70/700, 2020, Page(s) 561-562, ISSN 0960-1643
Publisher: Royal College of General Practitioners
DOI: 10.3399/bjgp20x713369

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Author(s): Wani S, Daroszewska A, Salter DM, van 't Hof RJ, Ralston SH, Albagha OME
Published in: Disease Models and Mechanisms, 2022, Page(s) 049318, ISSN 1754-8411
Publisher: Company of Biologists
DOI: 10.1242/dmm.049318

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation

Author(s): Mahéva Vallet, Antonia Sophocleous, Anna E. Törnqvist, Asim Azfer, Rob van’t Hof, Omar ME Albagha, Stuart H. Ralston
Published in: Calcified Tissue International, 2021, ISSN 0171-967X
Publisher: Springer Verlag
DOI: 10.1007/s00223-021-00827-2

Insertion mutation in Tnfrsf11a causes a Paget's disease‐like phenotype in heterozygous mice and osteopetrosis in homozygous mice

Author(s): Nerea Alonso, Sachin Wani, Lorraine Rose, Rob J van't Hof, Stuart H Ralston, Omar M E Albagha
Published in: Journal of Bone and Mineral Research, 2021, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4288

Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget’s disease of bone

Author(s): Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Owen Cronin, Mary Porteous, David Moore, Roseanne Cetnarskyj, Lakshminarayan Ranganath, Peter L Selby, Tolga Turgut, Geeta Hampson, Rama Chandra, Shu Ho, Jon Tobias, Steven Young-Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan C Y Tang, Luigi Gennari, Rannuccio Nuti, Maria Luisa Brandi, Javier Del Pino-Montes, J
Published in: Annals of the Rheumatic Diseases, Issue 83, 2024, Page(s) 529-536, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/ard-2023-224990