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Advancing knowledge to improve outcome in Paget’s disease of bone

Deliverables

Publications

Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status.

Author(s): Ilhame Diboun; Sachin Wani; Stuart H. Ralston; Omar M. E. Albagha; Omar M. E. Albagha
Published in: eLife, Issue 10/e65715, 2021, Page(s) 1-19, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65715

Bisphosphonates in the management of Paget's disease

Author(s): Ralston, SH
Published in: Bone, Issue 138, 2020, Page(s) 1-11, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2020.115465

Rare Inherited forms of Paget’s Disease and Related Syndromes

Author(s): Stuart H. Ralston, J. Paul Taylor
Published in: Calcified Tissue International, Issue 104/5, 2019, Page(s) 501-516, ISSN 0171-967X
Publisher: Springer Verlag
DOI: 10.1007/s00223-019-00520-5

Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort

Author(s): Owen Cronin, Deepak Subedi, Laura Forsyth, Kirsteen Goodman, Steff C Lewis, Catriona Keerie, Allan Walker, Mary Porteous, Roseanne Cetnarskyj, Lakshminarayan R Ranganath, Peter L Selby, Geeta Hampson, Rama Chandra, Shu Ho, Jon H Tobias, Steven A Young‐Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan Tang, Luigi Gennari, Rannuccio Nuti, Maria‐Luisa Brandi, Javier Pino‐Mont
Published in: Journal of Bone and Mineral Research, Issue 35/7, 2020, Page(s) 1246-1252, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4007

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget's Disease of Bone

Author(s): Diboun I, Wani S, Ralston SH, Albagha OME
Published in: Frontiers in Cell and Developmental Biology, 2022, Page(s) 903612, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2022.903612

Genetic Determinants of Paget’s Disease of Bone

Author(s): Navnit Makaram; Stuart H. Ralston
Published in: Makaram , N & Ralston , S H 2021 , ' Genetic determinants of Paget’s Disease of Bone ' , Current osteoporosis reports . https://doi.org/10.1007/s11914-021-00676-w, Issue 19, 2021, Page(s) 327-332, ISSN 1544-2241
Publisher: Springer-Nature
DOI: 10.1007/s11914-021-00676-w

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Author(s): Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Luigi Gennari, Núria Guañabens, M Kassim Javaid, Robert Layfield, Terence W O'Neill, R Graham G Russell, Michael D Stone, Keith Simpson, Diana Wilkinson, Ruth Wills, M Carola Zillikens, Stephen P Tuck
Published in: Journal of Bone and Mineral Research, Issue 34/4, 2019, Page(s) e3657, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3657

Paget’s disease of bone: when and why to refer to specialist care

Author(s): Catherine Nairn, Stuart H Ralston
Published in: British Journal of General Practice, Issue 70/700, 2020, Page(s) 561-562, ISSN 0960-1643
Publisher: Royal College of General Practitioners
DOI: 10.3399/bjgp20x713369

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Author(s): Wani S, Daroszewska A, Salter DM, van 't Hof RJ, Ralston SH, Albagha OME
Published in: Disease Models and Mechanisms, 2022, Page(s) 049318, ISSN 1754-8411
Publisher: Company of Biologists
DOI: 10.1242/dmm.049318

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation

Author(s): Mahéva Vallet, Antonia Sophocleous, Anna E. Törnqvist, Asim Azfer, Rob van’t Hof, Omar ME Albagha, Stuart H. Ralston
Published in: Calcified Tissue International, 2021, ISSN 0171-967X
Publisher: Springer Verlag
DOI: 10.1007/s00223-021-00827-2

Insertion mutation in Tnfrsf11a causes a Paget's disease‐like phenotype in heterozygous mice and osteopetrosis in homozygous mice

Author(s): Nerea Alonso, Sachin Wani, Lorraine Rose, Rob J van't Hof, Stuart H Ralston, Omar M E Albagha
Published in: Journal of Bone and Mineral Research, 2021, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4288

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