Advancing knowledge to improve outcome in Paget’s disease of bone

Información del proyecto

Paget-Advance

Identificador del acuerdo de subvención: 787270

DOI

10.3030/787270

Proyecto cerrado

Fecha de la firma de la CE 19 Junio 2018

Fecha de inicio 1 Agosto 2018

Fecha de finalización 31 Julio 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 422 623,00

Aportación de la UE

€ 2 422 623,00

Coordinado por

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data management plan

Data management

Publicaciones

Peer reviewed articles (13)

Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status.

Autores: Ilhame Diboun; Sachin Wani; Stuart H. Ralston; Omar M. E. Albagha; Omar M. E. Albagha
Publicado en: eLife, Edición 10/e65715, 2021, Página(s) 1-19, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.65715

Bisphosphonates in the management of Paget's disease

Autores: Ralston, SH
Publicado en: Bone, Edición 138, 2020, Página(s) 1-11, ISSN 8756-3282
Editor: Elsevier BV
DOI: 10.1016/j.bone.2020.115465

Rare Inherited forms of Paget’s Disease and Related Syndromes

Autores: Stuart H. Ralston, J. Paul Taylor
Publicado en: Calcified Tissue International, Edición 104/5, 2019, Página(s) 501-516, ISSN 0171-967X
Editor: Springer Verlag
DOI: 10.1007/s00223-019-00520-5

Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort

Autores: Owen Cronin, Deepak Subedi, Laura Forsyth, Kirsteen Goodman, Steff C Lewis, Catriona Keerie, Allan Walker, Mary Porteous, Roseanne Cetnarskyj, Lakshminarayan R Ranganath, Peter L Selby, Geeta Hampson, Rama Chandra, Shu Ho, Jon H Tobias, Steven A Young‐Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan Tang, Luigi Gennari, Rannuccio Nuti, Maria‐Luisa Brandi, Javier Pino‐Mont
Publicado en: Journal of Bone and Mineral Research, Edición 35/7, 2020, Página(s) 1246-1252, ISSN 0884-0431
Editor: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4007

Causes of Musculoskeletal Pain in Paget’s Disease of Bone

Autores: Kathryn Berg, Dervil Dockrell, Lesley Colvin, William D Fraser, Jonathan CY Tang, Terry Aspray, Elaine Dennison, Hrushikesh Divyateja, Nazim Ghouri, Esther Hanison, Richard Keen, Eugene McCloskey, Terence W O’Neill, Faizanur Rahman, Mashood Siddiqi, Stephen Tuck, Jane Turton, Stuart H Ralston
Publicado en: Calcified Tissue International, 2024, ISSN 1432-0827
Editor: Springer Nature
DOI: 10.1007/s00223-024-01279-0

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget's Disease of Bone

Autores: Diboun I, Wani S, Ralston SH, Albagha OME
Publicado en: Frontiers in Cell and Developmental Biology, 2022, Página(s) 903612, ISSN 2296-634X
Editor: Frontiers
DOI: 10.3389/fcell.2022.903612

Genetic Determinants of Paget’s Disease of Bone

Autores: Navnit Makaram; Stuart H. Ralston
Publicado en: Makaram , N & Ralston , S H 2021 , ' Genetic determinants of Paget’s Disease of Bone ' , Current osteoporosis reports . https://doi.org/10.1007/s11914-021-00676-w, Edición 19, 2021, Página(s) 327-332, ISSN 1544-2241
Editor: Springer-Nature
DOI: 10.1007/s11914-021-00676-w

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Autores: Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Luigi Gennari, Núria Guañabens, M Kassim Javaid, Robert Layfield, Terence W O'Neill, R Graham G Russell, Michael D Stone, Keith Simpson, Diana Wilkinson, Ruth Wills, M Carola Zillikens, Stephen P Tuck
Publicado en: Journal of Bone and Mineral Research, Edición 34/4, 2019, Página(s) e3657, ISSN 0884-0431
Editor: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3657

Paget’s disease of bone: when and why to refer to specialist care

Autores: Catherine Nairn, Stuart H Ralston
Publicado en: British Journal of General Practice, Edición 70/700, 2020, Página(s) 561-562, ISSN 0960-1643
Editor: Royal College of General Practitioners
DOI: 10.3399/bjgp20x713369

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Autores: Wani S, Daroszewska A, Salter DM, van 't Hof RJ, Ralston SH, Albagha OME
Publicado en: Disease Models and Mechanisms, 2022, Página(s) 049318, ISSN 1754-8411
Editor: Company of Biologists
DOI: 10.1242/dmm.049318

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation

Autores: Mahéva Vallet, Antonia Sophocleous, Anna E. Törnqvist, Asim Azfer, Rob van’t Hof, Omar ME Albagha, Stuart H. Ralston
Publicado en: Calcified Tissue International, 2021, ISSN 0171-967X
Editor: Springer Verlag
DOI: 10.1007/s00223-021-00827-2

Insertion mutation in Tnfrsf11a causes a Paget's disease‐like phenotype in heterozygous mice and osteopetrosis in homozygous mice

Autores: Nerea Alonso, Sachin Wani, Lorraine Rose, Rob J van't Hof, Stuart H Ralston, Omar M E Albagha
Publicado en: Journal of Bone and Mineral Research, 2021, ISSN 0884-0431
Editor: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4288

Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget’s disease of bone

Autores: Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Owen Cronin, Mary Porteous, David Moore, Roseanne Cetnarskyj, Lakshminarayan Ranganath, Peter L Selby, Tolga Turgut, Geeta Hampson, Rama Chandra, Shu Ho, Jon Tobias, Steven Young-Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan C Y Tang, Luigi Gennari, Rannuccio Nuti, Maria Luisa Brandi, Javier Del Pino-Montes, J
Publicado en: Annals of the Rheumatic Diseases, Edición 83, 2024, Página(s) 529-536, ISSN 0003-4967
Editor: BMJ Publishing Group
DOI: 10.1136/ard-2023-224990