Advancing knowledge to improve outcome in Paget’s disease of bone

Informazioni relative al progetto

Paget-Advance

ID dell’accordo di sovvenzione: 787270

DOI

10.3030/787270

Progetto chiuso

Data della firma CE 19 Giugno 2018

Data di avvio 1 Agosto 2018

Data di completamento 31 Luglio 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 422 623,00

Contributo UE

€ 2 422 623,00

Coordinato da

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (1)

Data management plan

Data management

Pubblicazioni

Peer reviewed articles (13)

Epigenetic analysis of Paget's disease of bone identifies differentially methylated loci that predict disease status.

Autori: Ilhame Diboun; Sachin Wani; Stuart H. Ralston; Omar M. E. Albagha; Omar M. E. Albagha
Pubblicato in: eLife, Numero 10/e65715, 2021, Pagina/e 1-19, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.65715

Bisphosphonates in the management of Paget's disease

Autori: Ralston, SH
Pubblicato in: Bone, Numero 138, 2020, Pagina/e 1-11, ISSN 8756-3282
Editore: Elsevier BV
DOI: 10.1016/j.bone.2020.115465

Rare Inherited forms of Paget’s Disease and Related Syndromes

Autori: Stuart H. Ralston, J. Paul Taylor
Pubblicato in: Calcified Tissue International, Numero 104/5, 2019, Pagina/e 501-516, ISSN 0171-967X
Editore: Springer Verlag
DOI: 10.1007/s00223-019-00520-5

Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort

Autori: Owen Cronin, Deepak Subedi, Laura Forsyth, Kirsteen Goodman, Steff C Lewis, Catriona Keerie, Allan Walker, Mary Porteous, Roseanne Cetnarskyj, Lakshminarayan R Ranganath, Peter L Selby, Geeta Hampson, Rama Chandra, Shu Ho, Jon H Tobias, Steven A Young‐Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan Tang, Luigi Gennari, Rannuccio Nuti, Maria‐Luisa Brandi, Javier Pino‐Mont
Pubblicato in: Journal of Bone and Mineral Research, Numero 35/7, 2020, Pagina/e 1246-1252, ISSN 0884-0431
Editore: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4007

Causes of Musculoskeletal Pain in Paget’s Disease of Bone

Autori: Kathryn Berg, Dervil Dockrell, Lesley Colvin, William D Fraser, Jonathan CY Tang, Terry Aspray, Elaine Dennison, Hrushikesh Divyateja, Nazim Ghouri, Esther Hanison, Richard Keen, Eugene McCloskey, Terence W O’Neill, Faizanur Rahman, Mashood Siddiqi, Stephen Tuck, Jane Turton, Stuart H Ralston
Pubblicato in: Calcified Tissue International, 2024, ISSN 1432-0827
Editore: Springer Nature
DOI: 10.1007/s00223-024-01279-0

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget's Disease of Bone

Autori: Diboun I, Wani S, Ralston SH, Albagha OME
Pubblicato in: Frontiers in Cell and Developmental Biology, 2022, Pagina/e 903612, ISSN 2296-634X
Editore: Frontiers
DOI: 10.3389/fcell.2022.903612

Genetic Determinants of Paget’s Disease of Bone

Autori: Navnit Makaram; Stuart H. Ralston
Pubblicato in: Makaram , N & Ralston , S H 2021 , ' Genetic determinants of Paget’s Disease of Bone ' , Current osteoporosis reports . https://doi.org/10.1007/s11914-021-00676-w, Numero 19, 2021, Pagina/e 327-332, ISSN 1544-2241
Editore: Springer-Nature
DOI: 10.1007/s11914-021-00676-w

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Autori: Stuart H Ralston, Luis Corral-Gudino, Cyrus Cooper, Roger M Francis, William D Fraser, Luigi Gennari, Núria Guañabens, M Kassim Javaid, Robert Layfield, Terence W O'Neill, R Graham G Russell, Michael D Stone, Keith Simpson, Diana Wilkinson, Ruth Wills, M Carola Zillikens, Stephen P Tuck
Pubblicato in: Journal of Bone and Mineral Research, Numero 34/4, 2019, Pagina/e e3657, ISSN 0884-0431
Editore: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3657

Paget’s disease of bone: when and why to refer to specialist care

Autori: Catherine Nairn, Stuart H Ralston
Pubblicato in: British Journal of General Practice, Numero 70/700, 2020, Pagina/e 561-562, ISSN 0960-1643
Editore: Royal College of General Practitioners
DOI: 10.3399/bjgp20x713369

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Autori: Wani S, Daroszewska A, Salter DM, van 't Hof RJ, Ralston SH, Albagha OME
Pubblicato in: Disease Models and Mechanisms, 2022, Pagina/e 049318, ISSN 1754-8411
Editore: Company of Biologists
DOI: 10.1242/dmm.049318

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation

Autori: Mahéva Vallet, Antonia Sophocleous, Anna E. Törnqvist, Asim Azfer, Rob van’t Hof, Omar ME Albagha, Stuart H. Ralston
Pubblicato in: Calcified Tissue International, 2021, ISSN 0171-967X
Editore: Springer Verlag
DOI: 10.1007/s00223-021-00827-2

Insertion mutation in Tnfrsf11a causes a Paget's disease‐like phenotype in heterozygous mice and osteopetrosis in homozygous mice

Autori: Nerea Alonso, Sachin Wani, Lorraine Rose, Rob J van't Hof, Stuart H Ralston, Omar M E Albagha
Pubblicato in: Journal of Bone and Mineral Research, 2021, ISSN 0884-0431
Editore: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4288

Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget’s disease of bone

Autori: Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Owen Cronin, Mary Porteous, David Moore, Roseanne Cetnarskyj, Lakshminarayan Ranganath, Peter L Selby, Tolga Turgut, Geeta Hampson, Rama Chandra, Shu Ho, Jon Tobias, Steven Young-Min, Malachi J McKenna, Rachel K Crowley, William D Fraser, Jonathan C Y Tang, Luigi Gennari, Rannuccio Nuti, Maria Luisa Brandi, Javier Del Pino-Montes, J
Pubblicato in: Annals of the Rheumatic Diseases, Numero 83, 2024, Pagina/e 529-536, ISSN 0003-4967
Editore: BMJ Publishing Group
DOI: 10.1136/ard-2023-224990