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Coincidence detection of proteins and lipids in regulation of cellular membrane dynamics

Ziel

Specific recruitment of different proteins to distinct intracellular membranes is fundamental in the biology of eukaryotic cells, but the molecular basis for specificity is incompletely understood. This proposal investigates the hypothesis that coincidence detection of proteins and lipids constitutes a major mechanism for specific recruitment of proteins to intracellular membranes in order to control cellular membrane dynamics. CODE will establish and validate mathematical models for coincidence detection, identify and functionally characterise novel coincidence detectors, and engineer artificial coincidence detectors as novel tools in cell biology and biotechnology.

Finanzierungsplan

ERC-ADG - Advanced Grant

Gastgebende Einrichtung

UNIVERSITETET I OSLO
Netto-EU-Beitrag
€ 1 905 625,00
Adresse
PROBLEMVEIEN 5-7
0313 Oslo
Norwegen

Auf der Karte ansehen

Region
Norge Oslo og Viken Oslo
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 2 500 000,00

Begünstigte (2)