Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
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Autori:
ANDREW C. HUNT, JAMES BRETT CASE, YOUNG-JUN PARK, LONGXING CAO, KEJIA WU, ALEXANDRA C. WALLS, ZHUOMING LIU, JOHN E. BOWEN, HSIEN-WEI YEH, SHALLY SAINI, LOUISA HELMS, YAN TING ZHAO, TIEN-YING HSIANG, T
Pubblicato in:
SCIENCE TRANSLATIONAL MEDICINE, 2022, ISSN 1946-6234
Editore:
American Association for the Advancement of Science
DOI:
10.1126/scitranslmed.abn1252
Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks
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Autori:
Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeli
Pubblicato in:
Nature Communications, 2021, ISSN 2041-1723
Editore:
Nature Publishing Group
DOI:
10.1038/s41467-021-27222-7
Interpreting neural networks for biological sequences by learning stochastic masks
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Autori:
Johannes Linder, Alyssa La Fleur, Zibo Chen, Ajasja Ljubetič, David Baker, Sreeram Kannan & Georg Seelig
Pubblicato in:
nature machine intelligence, 2021, ISSN 2522-5839
Editore:
Nature Group Publishing
DOI:
10.1038/s42256-021-00428-6