Periodic Reporting for period 1 - ET-PHOTOX (Functionalization of ethereal C-O Bonds Enabled by Metallaphotoredox Catalysis)
Periodo di rendicontazione: 2018-07-01 al 2020-06-30
ET-PHOTOX aims at establishing a general platform that combines visible light photocatalysis with nickel catalysis for tackling the challenge of the functionalization of ubiquitous ethereal aryl C-OMe bonds via CT complexes. The successful accomplishment of this project will be of significant value for the synthetic community, as ethereal C–O bonds are commonly present in biomass-derived feedstocks such as Lignin, the second most abundant biopolymer on the earth. ET-PHOTOX has provided the fellow with new knowledge and skills to broaden his future career as an independent researcher at the European Community.
The main objective of ET-PHOTOX was to develop an efficient paradigm for forging C–C bonds via the functionalization of ethereal aryl C–OMe bonds by the merger of nickel catalysis and photocatalysis. The specific objectives were the following:
1. To synthesize a variety of π-acceptor catalysts that will form a CT complex with aryl ethers
2. To implement dual photochemical C–C bond-forming reactions of anisole derivatives with carbon-based nucleophiles
3. To develop a photocarboxylation technology of aryl ethers with CO2 en route to benzoic acids