Objective Reliable, real-time detection systems for in-vivo, continuous monitoring of biological and chemical processes consist a crucial aspect in personalised healthcare. Nevertheless, even nowadays, the medical practice still lacks of systems providing a rapid, reliable and ultra-sensitive sensing in a continuous way. Meanwhile, inflammatory markers consist a pivotal tool in clinical practice since they may be indicators of specific diseases, along with signalising the response of a patient to a specific medical treatment. Nanotechnology-based devices exhibiting memristive electrical properties show great potential for delivering highly scalable, resilient, power efficient and reconfigurable electronic systems. In addition, when those particular nanodevices are subjected to appropriate surface treatments and implemented in the role of bio-inspired sensors, they can bring solutions and introduce novelty to the bio-sensing field regarding highly sensitive and robust detection of biomarkers, while expanding and broadening the research field and applications involving memristive phenomena. In the framework of this fellowship, a flexible, low-cost miniaturised minimally invasive sensing platform will be developed, implementing memristive nanoscale devices as intelligent bio-interfaces, allowing reliable, continuous and real-time monitoring of inflammatory markers. This scheme will be accomplished by the fabrication of a memristor-based sensing platform conjugated with a sensing membrane and an accordingly designed binding assay. Validation of the sensing platform for continuous monitoring will be followed by the integration on flexible substrates for in vivo measurements and integration with readout circuitry enabling the sensing data readout and the wireless transmission to a tablet or smartphone. Finally, the sensing platform will be applied for in-vivo, real-time monitoring, for the detection of inflammatory markers and for indicating the response to an applied treatment. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationsmobile phones Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2017 - Individual Fellowships Call for proposal H2020-MSCA-IF-2017 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator UNIVERSITY OF SOUTHAMPTON Net EU contribution € 183 454,80 Address Highfield SO17 1BJ Southampton United Kingdom See on map Region South East (England) Hampshire and Isle of Wight Southampton Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 183 454,80