Objetivo Reliable, real-time detection systems for in-vivo, continuous monitoring of biological and chemical processes consist a crucial aspect in personalised healthcare. Nevertheless, even nowadays, the medical practice still lacks of systems providing a rapid, reliable and ultra-sensitive sensing in a continuous way. Meanwhile, inflammatory markers consist a pivotal tool in clinical practice since they may be indicators of specific diseases, along with signalising the response of a patient to a specific medical treatment. Nanotechnology-based devices exhibiting memristive electrical properties show great potential for delivering highly scalable, resilient, power efficient and reconfigurable electronic systems. In addition, when those particular nanodevices are subjected to appropriate surface treatments and implemented in the role of bio-inspired sensors, they can bring solutions and introduce novelty to the bio-sensing field regarding highly sensitive and robust detection of biomarkers, while expanding and broadening the research field and applications involving memristive phenomena. In the framework of this fellowship, a flexible, low-cost miniaturised minimally invasive sensing platform will be developed, implementing memristive nanoscale devices as intelligent bio-interfaces, allowing reliable, continuous and real-time monitoring of inflammatory markers. This scheme will be accomplished by the fabrication of a memristor-based sensing platform conjugated with a sensing membrane and an accordingly designed binding assay. Validation of the sensing platform for continuous monitoring will be followed by the integration on flexible substrates for in vivo measurements and integration with readout circuitry enabling the sensing data readout and the wireless transmission to a tablet or smartphone. Finally, the sensing platform will be applied for in-vivo, real-time monitoring, for the detection of inflammatory markers and for indicating the response to an applied treatment. Ámbito científico engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationsmobile phones Programa(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Tema(s) MSCA-IF-2017 - Individual Fellowships Convocatoria de propuestas H2020-MSCA-IF-2017 Consulte otros proyectos de esta convocatoria Régimen de financiación MSCA-IF-EF-ST - Standard EF Coordinador UNIVERSITY OF SOUTHAMPTON Aportación neta de la UEn € 183 454,80 Dirección Highfield SO17 1BJ Southampton Reino Unido Ver en el mapa Región South East (England) Hampshire and Isle of Wight Southampton Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 183 454,80