Project description
Neuro-immune crosstalk contribution to mucosal immune response
Internal and external stimuli are recognised by the nervous and immune systems of the body. Stimuli signal integration and elicitation into proper responses are essential for maintaining homeostasis. However, the mechanisms involved remain unknown. The EU-funded ENTRI project proposes to develop a novel genetic approach and tools for the investigation of the neuro-immune crosstalk at mucosal surfaces, using various disease models. The study will enable selective evaluation of the neuronal and the immune response gene expression and function, resulting in a better understanding of how the neuro-immune crosstalk contributes to parasite immunity or allergic disease development. This project could potentially lead to a general concept of mucosal immune regulation.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
ERC-STG - Starting Grant
Host institution
10117 Berlin
Germany
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Beneficiaries (1)
10117 Berlin
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