Great ape organoids to reconstruct uniquely human development

Project Information

ANTHROPOID

Grant agreement ID: 803441

DOI 10.3030/803441

Project closed

EC signature date 3 May 2019

Start date 1 June 2019

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

F. HOFFMANN-LA ROCHE AG
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

CSS: cluster similarity spectrum integration of single-cell genomics data

Author(s): Zhisong He, Agnieska Brazovskaja, Sebastian Ebert, J. Gray Camp, Barbara Treutlein
Published in: Genome Biology, Issue 21/1, 2020, Page(s) 224-244, ISSN 1474-760X
Publisher: Springer Nature
DOI: 10.1186/s13059-020-02147-4

Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

Author(s): Jonas Simon Fleck, Fátima Sanchís-Calleja, Zhisong He, Malgorzata Santel, Michael James Boyle, J. Gray Camp, Barbara Treutlein
Published in: Cell Stem Cell, Issue 28, 2021, Page(s) 1-12, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2021.02.015

Charting human development using a multi-endodermal organ atlas and organoid models

Author(s): Qianhui Yu, Umut Kilik, Emily M. Holloway, Yu-Hwai Tsai, Christoph Harmel, Angeline Wu, Joshua H. Wu, Michael Czerwinski, Charlie J. Childs, Zhisong He, Meghan M. Capeling, Sha Huang, Ian A. Glass, Peter D.R. Higgins, Barbara Treutlein, Jason R. Spence, J. Gray Camp
Published in: Cell, Issue 184, 2021, Page(s) 1-18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.04.028

Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model

Author(s): Yu-Han Hung, Sha Huang, Michael K Dame, Qianhui Yu, Qing C Yu, Yi A Zeng, J Gray Camp, Jason R Spence, Praveen Sethupathy
Published in: Nucleic Acids Research, Issue 49/2, 2021, Page(s) 726-744, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkaa1204

Resolving Neurodevelopmental and Vision Disorders Using Organoid Single-Cell Multi-omics

Author(s): Giovanna Brancati, Barbara Treutlein, J. Gray Camp
Published in: Neuron, Issue 107/6, 2020, Page(s) 1000-1013, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2020.09.001

Lineage recording in human cerebral organoids

Author(s): Zhisong He, Ashley Maynard, Akanksha Jain, Tobias Gerber, Rebecca Petri, Hsiu-Chuan Lin, Malgorzata Santel, Kevin Ly, Jean-Samuel Dupré, Leila Sidow, Fatima Sanchis Calleja, Sophie M. J. Jansen, Stephan Riesenberg, J. Gray Camp, Barbara Treutlein
Published in: Nature Methods, 2021, Page(s) 90-99, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-021-01344-8

Mapping human cell phenotypes to genotypes with single-cell genomics

Author(s): J. Gray Camp, Randall Platt, Barbara Treutlein
Published in: Science, Issue 365/6460, 2019, Page(s) 1401-1405, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aax6648

Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions

Author(s): Michael Dannemann, Zhisong He, Christian Heide, Benjamin Vernot, Leila Sidow, Sabina Kanton, Anne Weigert, Barbara Treutlein, Svante Pääbo, Janet Kelso, J. Gray Camp
Published in: Stem Cell Reports, Issue 15/1, 2020, Page(s) 214-225, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.05.018

Organoid single-cell genomic atlas uncovers human-specific features of brain development

Author(s): Sabina Kanton, Michael James Boyle, Zhisong He, Malgorzata Santel, Anne Weigert, Fátima Sanchís-Calleja, Patricia Guijarro, Leila Sidow, Jonas Simon Fleck, Dingding Han, Zhengzong Qian, Michael Heide, Wieland B. Huttner, Philipp Khaitovich, Svante Pääbo, Barbara Treutlein, J. Gray Camp
Published in: Nature, Issue 574/7778, 2019, Page(s) 418-422, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1654-9

Spatial transcriptomic and single-nucleus analysis reveals heterogeneity in a gigantic single-celled syncytium

Author(s): Nico Schramma; Cristina Loureiro; Tobias Gerber; Siyu Chen; Akanksha Jain; Anne Weber; Anne Weigert; Malgorzata Santel; Karen Alim; Barbara Treutlein; J Gray Camp
Published in: eLife, Issue 1, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.3929/ethz-b-000535011

Book chapters (1)

Single-cell genomic analysis of human cerebral organoids

Author(s): Sabina Kanton, Barbara Treutlein, J. Gray Camp
Published in: Human Pluripotent Stem Cell Derived Organoid Models, Issue 159, 2020, Page(s) 229-256, ISBN 9780128215319
Publisher: Elsevier
DOI: 10.1016/bs.mcb.2020.03.013