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Zooming the link between diet and brain health: how phenolic metabolites modulate brain inflammation

Project description

How dietary phenolics delay neurodegenerative diseases

It is believed that a diet rich in phenolics delays neurodegenerative diseases in the ageing population. However, the mechanistic actions of phenolics in brain health remain under examination. The EU-funded LIMBo project aims to analyse the ability of dietary phenolics to prevent and delay neuroinflammation, a central process in neurodegenerative diseases. The project will focus on metabolites derived from dietary phenolics by investigating their effects in both the established and unknown pathways of microglia cells. LIMBo will deliver essential knowledge that improves understanding of the diversity of phenolic metabolites, their specific impact on neuroinflammation and the potential use as pro-drugs. Moreover, it will produce valuable scientific insights for future implementation of healthy brain diets.

Host institution

UNIVERSIDADE NOVA DE LISBOA
Net EU contribution
€ 1 199 697,00
Address
Campus De Campolide
1099 085 Lisboa
Portugal

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Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Beneficiaries (2)

UNIVERSIDADE NOVA DE LISBOA
Portugal
Net EU contribution
€ 1 199 697,00
Address
Campus De Campolide
1099 085 Lisboa

See on map

Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portugal
Net EU contribution
€ 296 325,00
Address
Avenida Da Republica Quinta Do Marques
2781-901 Oeiras

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Research Organisations
Other funding
€ 0,00