Project description
The determinants of metabolic health – the role of inflammation
Obesity is known to cause various metabolic comorbidities, such as diabetes. Although inflammation is a key driver of metabolic diseases, anti-inflammatory drugs have not shown any therapeutic efficacy. The MATRIX is an EU-funded project that is investigating the differences between metabolically healthy and unhealthy individuals. Scientists are working under the hypothesis that the ability to resolve inflammation and not pro-inflammation is what differentiates the two states. Using cutting-edge techniques, scientists will focus on adipose extracellular-matrix remodelling mechanisms and evaluate the therapeutic potential of pro-resolving lipids in patient-derived cell lines. Results may lead to a novel approach to tackle obesity-related pathologies.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
ERC-STG - Starting Grant
Host institution
8000 Aarhus C
Denmark
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Beneficiaries (2)
8000 Aarhus C
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Participation ended
405 30 Goeteborg