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Inflammatory resolution and remodelling of the adipose extracellular matrix: key determinants of a metabolically healthy phenotype?

Project description

The determinants of metabolic health – the role of inflammation

Obesity is known to cause various metabolic comorbidities, such as diabetes. Although inflammation is a key driver of metabolic diseases, anti-inflammatory drugs have not shown any therapeutic efficacy. The MATRIX is an EU-funded project that is investigating the differences between metabolically healthy and unhealthy individuals. Scientists are working under the hypothesis that the ability to resolve inflammation and not pro-inflammation is what differentiates the two states. Using cutting-edge techniques, scientists will focus on adipose extracellular-matrix remodelling mechanisms and evaluate the therapeutic potential of pro-resolving lipids in patient-derived cell lines. Results may lead to a novel approach to tackle obesity-related pathologies.

Host institution

AARHUS UNIVERSITET
Net EU contribution
€ 1 657 123,03
Address
Nordre Ringgade 1
8000 Aarhus C
Denmark

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Region
Danmark Midtjylland Østjylland
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Beneficiaries (2)

AARHUS UNIVERSITET
Denmark
Net EU contribution
€ 1 657 123,03
Address
Nordre Ringgade 1
8000 Aarhus C

See on map

Region
Danmark Midtjylland Østjylland
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
GOETEBORGS UNIVERSITET

Participation ended

Sweden
Net EU contribution
€ 42 878,97
Address
Vasaparken
405 30 Goeteborg
Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00