Inflammatory resolution and remodelling of the adipose extracellular matrix: key determinants of a metabolically healthy phenotype?

Informations projet

The MATRIX

N° de convention de subvention: 804418

DOI

10.3030/804418

Date de signature de la CE 6 Novembre 2018

Date de début 1 Septembre 2019

Date de fin 28 Février 2026

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total

€ 1 700 002,00

Contribution de l’UE

€ 1 700 002,00

Coordonné par

AARHUS UNIVERSITET
Denmark

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Publications

Peer reviewed articles (14)

Healthy Subcutaneous and Omental Adipose Tissue Is Associated with High Expression of Extracellular Matrix Components

Auteurs: Matúš Soták; Meenu Rohini Rajan; Madison Clark; Christina Biörserud; Ville Wallenius; Carolina E. Hagberg; Emma Börgeson
Publié dans: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23010520

The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development

Auteurs: Picarda E, Galbo PM Jr, Zong H, Rajan MR, Wallenius V, Zheng D, Börgeson E, Singh R, Pessin J, Zang X.
Publié dans: Sciences Advances, 2022, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abm7012

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum.

Auteurs: Meenu Rohini Rajan; Matúš Soták; Fredrik Barrenäs; Fredrik Barrenäs; Tong Shen; Kamil Borkowski; Nicholas J. Ashton; Christina Biörserud; Tomas L. Lindahl; Sofia Ramström; Sofia Ramström; Michael Schöll; Michael Schöll; Per Lindahl; Oliver Fiehn; John W. Newman; John W. Newman; Rosie Perkins; Ville Wallenius; Stephan Lange; Stephan Lange; Emma Börgeson; Emma Börgeson
Publié dans: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019), 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-51673-0

miR-486 is modulated by stretch and increases ventricular growth

Auteurs: Stephan Lange; Stephan Lange; Indroneal Banerjee; Katrina Carrion; Ricardo Serrano; Louisa Habich; Rebecca J Kameny; Luisa Lengenfelder; Nancy D. Dalton; Rudolph Meili; Emma Börgeson; Kirk L. Peterson; Marco Ricci; Joy Lincoln; Majid Ghassemian; Jeffery R. Fineman; Juan C. del Álamo; Vishal Nigam; Vishal Nigam; Vishal Nigam
Publié dans: JCI Insight, 2019, ISSN 2379-3708
Éditeur: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.125507

Of mice and men: Pinpointing species differences in adipose tissue biology

Auteurs: Emma Börgeson; Jeremie Boucher; Carolina E Hagberg
Publié dans: Frontiers in Cell and Developmental Biology, 2022, ISSN 2296-634X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fcell.2022.1003118

Specialized Pro-Resolving Mediators and the Lymphatic System.

Auteurs: Jamie Kraft; Robert Blomgran; Iben Lundgaard; Marianne Quiding-Järbrink; Jonathan S. Bromberg; Emma Börgeson; Emma Börgeson
Publié dans: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22052750

The N2A region of titin has a unique structural configuration.

Auteurs: Chiara Stronczek; Stephan Lange; Stephan Lange; Belinda Bullard; Sebastian Wolniak; Emma Börgeson; Olga Mayans; Jennifer R. Fleming
Publié dans: The Journal of General Physiology, 2021, ISSN 0022-1295
Éditeur: Rockefeller University Press
DOI: 10.1085/jgp.202012766

Intestinal sodium/glucose cotransporter 3 expression is epithelial and downregulated in obesity

Auteurs: Soták M, Casselbrant A, Rath E, Zietek T, Strömstedt M, Adingupu DD, Karlsson D, Fritsch Fredin M, Ergang P, Pácha J, Batorsky A, Alpers CE, Börgeson E, Hansen PBL, Ericsson A, Björnson Granqvist A, Wallenius V, Fändriks L, Unwin RJ
Publié dans: Life Sciences, 2021, ISSN 0024-3205
Éditeur: Elsevier BV
DOI: 10.1016/j.lfs.2020.118974

The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity

Auteurs: Ibrahim AlZaim; Laura P M H de Rooij; Bilal N Sheikh; Emma Börgeson; Joanna Kalucka
Publié dans: Nature Reviews Endocrinology, 2023, Page(s) 19(12): 691-707, ISSN 1759-5029
Éditeur: Nature Publishing Group
DOI: 10.1038/s41574-023-00893-6

Exploring Obscurin and SPEG Kinase Biology.

Auteurs: Jennifer R. Fleming; Alankrita Rani; Jamie Kraft; Sanja Zenker; Emma Börgeson; Emma Börgeson; Stephan Lange; Stephan Lange
Publié dans: Journal of Clinical Medicine, 2021, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10050984

Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis

Auteurs: Jamie D. Kraft; Robert Blomgran; Ida Bergström; Matúš Soták; Madison Clark; Alankrita Rani; Meenu Rohini Rajan; Jesmond Dalli; Sofia Nyström; Marianne Quiding‐Järbrink; Jonathan Bromberg; Per Skoog; Emma Börgeson
Publié dans: Crossref, 2022, ISSN 0892-6638
Éditeur: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202101219rr

Challenges in PhD education due to COVID-19 - disrupted supervision or business as usual: a cross-sectional survey of Swedish biomedical sciences graduate students.

Auteurs: Emma Börgeson; Matúš Soták; Jamie Kraft; Grace Bagunu; Christina Biörserud; Stephan Lange; Stephan Lange
Publié dans: BMC Medical Education, Vol 21, Iss 1, Pp 1-11 (2021), 2021, ISSN 1472-6920
Éditeur: BioMed Central
DOI: 10.21203/rs.3.rs-318234/v1

Molecular Characterisation of Titin N2A and Its Binding of CARP Reveals a Titin/Actin Cross-linking Mechanism

Auteurs: Zhou T, Fleming JR, Lange S, Hessel AL, Bogomolovas J, Stronczek C, Grundei D, Ghassemian M, Biju A, Börgeson E, Bullard B, Linke WA, Chen J, Kovermann M, Mayans O.
Publié dans: The Journal of Molecular Biology, 2021, ISSN 0022-2836
Éditeur: Academic Press
DOI: 10.1016/j.jmb.2021.166901

Students at a crossroad: A cross-sectional survey gauging the impact of COVID-19 on medical and biomedical graduates in the United States and Sweden

Auteurs: Stephan Lange; Matúš Soták; Carolina E Hagberg; Grace Bagunu; Sylvi Vigmo; Emma Börgeson
Publié dans: Biochemistry and Molecular Biology Education, 2023, ISSN 1470-8175
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1002/bmb.21761