Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Risultati finali

Pubblicazioni

Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection

Autori: Konstantinos Giannakis; Amanda K. Broz; Daniel B. Sloan; Iain G. Johnston
Pubblicato in: G3, Numero 13, 2023, Pagina/e jkad068, ISSN 2160-1836
Editore: Genetics Society of America
DOI: 10.1101/2022.09.06.506828

Intracellular Energy Variability Modulates Cellular Decision-Making Capacity

Autori: R Kerr, S Jabbari, IG Johnston
Pubblicato in: Scientific Reports, Numero 91, 2019, Pagina/e p20196, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-56587-5

Evolutionary inference across eukaryotes identifies universal features shaping organelle gene retention

Autori: Konstantinos Giannakis, Samuel J. Arrowsmith, Luke Richards, Sara Gasparini, Joanna M. Chustecki, Ellen C. Røyrvik, Iain G. Johnston
Pubblicato in: Cell Systems, Numero 13, 2022, Pagina/e 874-884, ISSN 2405-4712
Editore: Elsevier
DOI: 10.1016/j.cels.2022.08.007

Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck.

Autori: David M. Edwards; Ellen C. Røyrvik; Joanna M. Chustecki; Konstantinos Giannakis; Robert C. Glastad; Arunas L. Radzvilavicius; Iain G. Johnston
Pubblicato in: PLoS Biology, Vol 19, Iss 4, p e3001153 (2021), Numero 1, 2020, ISSN 1544-9173
Editore: Public Library of Science
DOI: 10.1371/journal.pbio.3001153

Efficient inference of evolutionary and progressive dynamics on hypercubic transition graphs

Autori: Marcus T. Moen; Iain G. Johnston
Pubblicato in: Bioinformatics, Numero 39, 2023, Pagina/e btac803, ISSN 1367-4811
Editore: Oxford University Press
DOI: 10.1101/2022.05.09.491130

Stochastic organelle genome segregation through <i>Arabidopsis</i> development and reproduction

Autori: Amanda K. Broz; Daniel B. Sloan; Iain G. Johnston
Pubblicato in: New Phytologist, Numero 241, 2024, Pagina/e 896-910, ISSN 0028-646X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/nph.19288

Cellular and environmental dynamics influence species-specific extents of organelle gene retention

Autori: Belén García Pascual; Jan M. Nordbotten; Iain G. Johnston
Pubblicato in: Proceedings of the Royal Society B, Numero 290, 2023, Pagina/e 20222140, ISSN 0962-8452
Editore: Royal Society of London
DOI: 10.1101/2022.10.17.512581

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions

Autori: Robert C. Glastad; Iain G. Johnston
Pubblicato in: PLoS Computational Biology, Numero 19, 2023, Pagina/e e1010953, ISSN 1553-734X
Editore: Public Library of Science
DOI: 10.1101/2022.06.27.497759

Collective mitochondrial dynamics resolve conflicting cellular tensions: From plants to general principles

Autori: Joanna M Chustecki, Iain G Johnston
Pubblicato in: Seminars in Cell & Developmental Biology, Numero 156, 2024, Pagina/e 253-265, ISSN 1084-9521
Editore: Academic Press
DOI: 10.1016/j.semcdb.2023.09.005

Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease

Autori: Mona Synnøve Bjune Laurence Lawrence-Archer Johnny Laupsa-Borge Cathrine Horn Sommersten Adrian McCann Robert Clay Glastad Iain George Johnston Matthias Kern Matthias Blüher Gunnar Mellgren Simon N. Dankel
Pubblicato in: eBioMedicine, Numero 91, 2023, ISSN 2352-3964
Editore: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104569

MtDNA sequence features associated with ‘selfish genomes’ predict tissue-specific segregation and reversion

Autori: Ellen C Røyrvik, Iain G Johnston
Pubblicato in: Nucleic Acids Research, Numero 48/15, 2020, Pagina/e 8290-8301, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkaa622

Exchange on dynamic encounter networks allows plant mitochondria to collect complete sets of mitochondrial DNA products despite their incomplete genomes

Autori: Konstantinos Giannakis; Joanna M. Chustecki; Iain G. Johnston
Pubblicato in: Quantitative Plant Biology, Numero 3, 2022, Pagina/e e18, ISSN 2632-8828
Editore: Cambridge University Press
DOI: 10.1017/qpb.2022.15

Mitochondrial Network State Scales mtDNA Genetic Dynamics

Autori: Juvid Aryaman, Charlotte Bowles, Nick S. Jones, Iain G. Johnston
Pubblicato in: Genetics, Numero 212/4, 2019, Pagina/e 1429-1443, ISSN 0016-6731
Editore: Genetics Society of America
DOI: 10.1534/genetics.119.302423

Intracellular Energy Variability Modulates Cellular Decision-Making Capacity

Autori: Iain G. Johnston; Iain G. Johnston; Ryan Kerr; Sara Jabbari
Pubblicato in: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019), Numero 1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1101/2019.12.13.875427

Evolving mtDNA populations within cells

Autori: Iain G. Johnston, Joerg P. Burgstaller
Pubblicato in: Biochemical Society Transactions, Numero 47/5, 2019, Pagina/e 1367-1382, ISSN 0300-5127
Editore: Portland Press, Ltd.
DOI: 10.1042/bst20190238

Sorting of mitochondrial and plastid heteroplasmy in Arabidopsis is extremely rapid and depends on MSH1 activity

Autori: AK Broz, A Keene, M Fernandes Gyorfy, M Hodous, IG Johnston, DB Sloan
Pubblicato in: PNAS, Numero 119, 2022, Pagina/e e2206973119, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2206973119

Stromule geometry allows optimal spatial regulation of organelle interactions in the quasi-2D cytoplasm

Autori: Jessica Lee Erickson; Jennifer Prautsch; Frisine Reynvoet; Frederik Niemeyer; Gerd Hause; Iain G. Johnston; Martin Schattat
Pubblicato in: Plant and Cell Physiology, Numero pcad098, 2023, ISSN 0032-0781
Editore: Oxford University Press
DOI: 10.1101/2023.04.27.538610

2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA

Autori: Boris Pantic, Daniel Ives, Mara Mennuni, Diego Perez-Rodriguez, Uxoa Fernandez-Pelayo, Amaia Lopez de Arbina, Mikel Muñoz-Oreja, Marina Villar-Fernandez, Thanh-mai Julie Dang, Lodovica Vergani, Iain G. Johnston, Robert D. S. Pitceathly, Robert McFarland, Michael G. Hanna, Robert W. Taylor, Ian J. Holt & Antonella Spinazzola
Pubblicato in: Nature Communications, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-26829-0

Altered collective mitochondrial dynamics in the Arabidopsis<i>msh1</i>mutant compromising organelle DNA maintenance

Autori: Joanna M Chustecki; Ross D Etherington; Daniel J Gibbs; Iain G Johnston
Pubblicato in: Journal of Experimental Botany, Numero 73, 2022, Pagina/e 5428-5439, ISSN 0022-0957
Editore: Oxford University Press
DOI: 10.1093/jxb/erac250

Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics

Autori: Ana Victoria Lechuga-Vieco, Ana Latorre-Pellicer, Iain G. Johnston, Gennaro Prota, Uzi Gileadi, Raquel Justo-Méndez, Rebeca Acín-Pérez, Raquel Martínez-de-Mena, Jose María Fernández-Toro, Daniel Jimenez-Blasco, Alfonso Mora, Jose A. Nicolás-Ávila, Demetrio J. Santiago, Silvia G. Priori, Juan Pedro Bolaños, Guadalupe Sabio, Luis Miguel Criado, Jesús Ruíz-Cabello, Vincenzo Cerundolo, Nick
Pubblicato in: Science Advances, Numero 6/31, 2020, Pagina/e eaba5345, ISSN 2375-2548
Editore: Science
DOI: 10.1126/sciadv.aba5345

Network analysis of Arabidopsis mitochondrial dynamics reveals a resolved tradeoff between physical distribution and social connectivity

Autori: Joanna M.Chustecki, Daniel J.Gibbs, George W.Bassel, Iain G.Johnston
Pubblicato in: Cell Systems, 2021, ISSN 2405-4712
Editore: Cell Systems
DOI: 10.1016/j.cels.2021.04.006

Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys

Autori: Arunas L. Radzvilavicius; Iain G. Johnston
Pubblicato in: Frontiers in Genetics, Numero 13, 2022, Pagina/e 974472, ISSN 1664-8021
Editore: Frontiers Media
DOI: 10.1101/2021.01.28.428572

Varied Mechanisms and Models for the Varying Mitochondrial Bottleneck

Autori: Iain G. Johnston
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 7, 2019, ISSN 2296-634X
Editore: Frontiers
DOI: 10.3389/fcell.2019.00294

Efficient vasculature investment in tissues can be determined without global information.

Autori: Salva Duran-Nebreda; Iain G. Johnston; George W. Bassel
Pubblicato in: Journal of the Royal Society Interface, Numero 17, 2020, Pagina/e 20200137, ISSN 1742-5689
Editore: The Royal Society
DOI: 10.1098/rsif.2020.0137

Risultati finali

Pubblicazioni

Condividi questa pagina

Scarica