Descrizione del progetto
Un’alternativa più sicura alla formaldeide per l’istopatologia
L’esame microscopico dei tessuti umani è una tecnica standard utilizzata per la diagnosi delle malattie. Per preservare l’architettura e il profilo molecolare dei campioni bioptici di tessuto umano, i laboratori di istopatologia in tutto il mondo utilizzano come fissativo la formalina, una soluzione a base di formaldeide. La formaldeide è tuttavia classificata come cancerogeno di classe 1B, mettendo a rischio quotidiano gli operatori sanitari di tutto il mondo. Il progetto EARTH, finanziato dall’UE, ha creato Fixocare®, una formulazione fissativa a base di prodotti naturali, come alternativa sicura alla formaldeide. Oltre a ridurre il rischio di inalazione e di irritazione cutanea, Fixocare® è più sicuro da smaltire e non provoca contaminazione ambientale.
Obiettivo
Environmentally friendly Alternative to Revolutionise the use of formaldehyde in The Histopathology (human tissue) fixative market.
The present: The microscopic examination of tissue in order to study the manifestations of disease is the science known as histopathology. Human tissue biopsy samples are taken every day in hospitals around the world and ‘fixed’ in a formaldehyde solution fixative, known as Formalin.
The problem: Healthcare workers globally are exposed to formaldehyde for 8 hours a day on a daily basis. Formaldehyde is classified as a hazardous substance.1. Daily, formaldehyde is first used in the operation theatres for preservation of tissue/biopsy tissue samples, which are then transported to the analytical laboratories, where, the second use of formaldehyde in the tissue fixation for microscopic examination occurs.
Personnel exposure and the subsequent waste disposal are major issues. The European Chemicals Agency has classified Formaldehyde as a Class 1b carcinogen: EC number: 200-001-8 CAS number: 50-00-02. Formaldehyde use is regulated by the Carcinogens Directive in EU workplaces, exposure levels have been reduced from 4ppm to 0.4ppm over an 8h period and 2ppm to 0.2ppm for a 15min period3, the rationale behind this proposal is for alternatives to formaldehyde to be found.
T
he business opportunity: Serosep Ltd., a SME presents Fixocare®, a fixative formulation made from natural products as a solution, which it plans to introduce to the histopathology community as a safe alternative to formaldehyde solutions.
Campo scientifico
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-SMEINST-1-2016-2017
Meccanismo di finanziamento
SME-1 - SME instrument phase 1Coordinatore
V94FF83 ANNACOTTY LIMERICK
Irlanda
L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione.