Publications Peer reviewed articles (33) Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function Author(s): Natália da Silva Lima, Marcos F Fondevila, Eva Nóvoa, Xabier Buqué, Maria Mercado-Gómez, Sarah Gallet, Maria J González-Rellan, Uxia Fernandez, Anne Loyens, Maria Garcia-Vence, Maria Del Pilar Chantada-Vazquez, Susana B Bravo, Patricia Marañon, Ana Senra, Adriana Escudero, Magdalena Leiva, Diana Guallar, Miguel Fidalgo, Pedro Gomes, Marc Claret, Guadalupe Sabio, Marta Varela-Rey, Teresa C De Published in: J. Hepatol., Issue 2022 Jan;76(1, 2022, Page(s) 11-24, ISSN 0168-8278 Publisher: Elsevier BV DOI: 10.1016/j.jhep.2021.09.008 Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels. Author(s): Erika Cecon, Daniela Fernandois, Nicolas Renault, Caio Fernando Ferreira Coelho, Jan Wenzel, Corentin Bedart, Charlotte Izabelle, Sarah Gallet, Sophie Le Poder, Bernard Klonjkowski, Markus Schwaninger, Vincent Prevot, Julie Dam, Ralf Jockers Published in: Cell Mol Life Sci, Issue 2022; 79(7), 2022, Page(s) 361, ISSN 1420-682X Publisher: Birkhauser Verlag DOI: 10.1007/s00018-022-04390-3 Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency Author(s): Sivaraj M Sundaram, Adriana Arrulo Pereira, Helge Müller-Fielitz, Hannes Köpke, Meri De Angelis, Timo D Müller, Heike Heuer, Jakob Körbelin, Markus Krohn, Jens Mittag, Ruben Nogueiras, Vincent Prevot, Markus Schwaninger Published in: Brain, 2022, ISSN 0006-8950 Publisher: Oxford University Press DOI: 10.1093/brain/awac243 Short regulatory DNA sequences to target brain endothelial cells for gene therapy Author(s): Hanna Graßhoff, Helge Müller-Fielitz, Godwin K Dogbevia, Jakob Körbelin, Jacqueline Bannach, Carl MG Vahldieck, Kristina Kusche-Vihrog, Olaf Jöhren, Oliver J Müller, Ruben Nogueiras, Vincent Prevot, Markus Schwaninger Published in: J Cereb Blood Flow Metab, Issue 2022 Jan; 42(1), 2022, Page(s) 104–120, ISSN 0271-678X Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1177/0271678x211039617 Hepatic p63 regulates glucose metabolism by repressing SIRT1 Author(s): Maria J Gonzalez-Rellan, Eva Novoa, Natalia da Silva Lima, Amaia Rodriguez, Christelle Veyrat-Durebex, Samuel Seoane, Begoña Porteiro, Marcos F Fondevila, Uxia Fernandez,1 Marta Varela-Rey,6 Ana Senra,1 Cristina Iglesias,1 Adriana Escudero,1 Miguel Fidalgo,1 Diana Guallar,7 Roman Perez-Fernandez,1 Vincent Prevot,8 Markus Schwaninger,9 Miguel López,1,2 Carlos Dieguez,1,2 Roberto Coppari,4,5 Gema Published in: Gut, Issue 2023 Mar; 72(3), 2023, Page(s) 472–483, ISSN 0017-5749 Publisher: BMJ Publishing Group DOI: 10.1136/gutjnl-2021-326620 Cerebral angiogenesis ameliorates pathological disorders in Nemo -deficient mice with small-vessel disease Author(s): Yun Jiang, Kristin Müller, Mahtab A. Khan, Julian C. Assmann, Josephine Lampe, Knut Kilau, Marius Richter, Maximilian Kleint, Dirk A Ridder, Norbert Hübner, Marc Schmidt-Supprian, Jan Wenzel, Markus Schwaninger Published in: Journal of Cerebral Blood Flow & Metabolism, Issue 41/2, 2021, Page(s) 219-235, ISSN 0271-678X Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1177/0271678x20910522 Brain JNK and metabolic disease Author(s): Rubén Nogueiras, Guadalupe Sabio Published in: Diabetologia, Issue 64/2, 2021, Page(s) 265-274, ISSN 0012-186X Publisher: Springer Verlag DOI: 10.1007/s00125-020-05327-w Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function Author(s): Manon Duquenne, Cintia Folgueira, Cyril Bourouh, Marion Millet, Anisia Silva, Jérôme Clasadonte, Monica Imbernon, Daniela Fernandois, Ines Martinez-Corral, Soumya Kusumakshi, Emilie Caron, S. Rasika, Eleonora Deliglia, Nathalie Jouy, Asturo Oishi, Massimiliano Mazzone, Eric Trinquet, Jan Tavernier, Young-Bum Kim, Stéphane Ory, Ralf Jockers, Markus Schwaninger, Ulrich Boehm, Ruben Nogueiras, Jea Published in: Nature Metabolism, 2021, ISSN 2522-5812 Publisher: Nature Portfolio DOI: 10.1038/s42255-021-00432-5 How COVID-19 affects microvessels in the brain Author(s): Jan Wenzel, Markus Schwaninger Published in: Brain, 2022, ISSN 0006-8950 Publisher: Oxford University Press DOI: 10.1093/brain/awac211 Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons. Author(s): Tori Lhomme; Jerome Clasadonte; Monica Imbernon; Daniela Fernandois; Florent Sauve; Emilie Caron; Natália da Silva Lima; Violeta Heras; Ines Martinez-Corral; Helge Mueller-Fielitz; Sowmyalakshmi Rasika; Markus Schwaninger; Rubén Nogueiras; Vincent Prevot Published in: J Clin Invest, Issue 8, 2021, ISSN 0021-9738 Publisher: American Society for Clinical Investigation DOI: 10.1172/jci140521 NF-κB signaling in tanycytes mediates inflammation-induced anorexia Author(s): Mareike Böttcher, Helge Müller-Fielitz, Sivaraj M. Sundaram, Sarah Gallet, Vanessa Neve, Kiseko Shionoya, Adriano Zager, Ning Quan, Xiaoyu Liu, Ruth Schmidt-Ullrich, Ronny Haenold, Jan Wenzel, Anders Blomqvist, David Engblom, Vincent Prevot, Markus Schwaninger Published in: Molecular Metabolism, Issue 39, 2020, Page(s) 101022, ISSN 2212-8778 Publisher: Elsevier GmbH DOI: 10.1016/j.molmet.2020.101022 Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis. Author(s): Wineke Bakker; Monica Imbernon; Casper Gravesen Salinas; Daniela Herrera Moro Chao; Rim Hassouna; Chloe Morel; Claire Martin; Caroline Leger; Raphael G.P. Denis; Julien Castel; Andreas Peter; Martin Heni; Walter Maetzler; Heidi Solvang Nielsen; Manon Duquenne; Markus Schwaninger; Sofia Lundh; Wouter Frederic Johan Hogendorf; Giuseppe Gangarossa; Anna Secher; Jacob Hecksher-Sørensen; Thomas Åskov Published in: Cell Rep. 41:111698 (2022), Issue 7, 2022, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2022.111698 The Role of Tanycytes in the Hypothalamus-Pituitary-Thyroid Axis and the Possibilities for Their Genetic Manipulation Author(s): Helge Müller-Fielitz, Markus Schwaninger Published in: Experimental and Clinical Endocrinology & Diabetes, Issue 128/06/07, 2020, Page(s) 388-394, ISSN 0947-7349 Publisher: Johann Ambrosius Barth DOI: 10.1055/a-1065-1855 The SARS-CoV-2 main protease M-pro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells Author(s): Josephine Lampe; Jan Wenzel; Helge Müller-Fielitz; Kristin Müller; Raphael Schuster; Linlin Zhang; Marietta Zille; Markus Krohn; Ümit Özorhan; Yun Jiang; Vanessa Neve; Anke Fähnrich; Fabian Ott; Sonja Binder; Hauke Busch; Ludovic Collin; Roberto Villasenor; Olaf Jöhren; Hermann Altmeppen; Manolis Pasparakis; Ruben Nogueiras; Vincent Prevot; Rolf Hilgenfeld; Markus Glatzel; Markus Schwaninger Published in: Nature neuroscience, Issue 10, 2021, ISSN 1097-6256 Publisher: Nature Publishing Group DOI: 10.21203/rs.3.rs-86988/v1 Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity? Author(s): Elvira S. Sandin; Julica Folberth; Helge Müller-Fielitz; Claus U. Pietrzik; Elisabeth Herold; Thomas E. Willnow; Paul T. Pfluger; Ruben Nogueiras; Vincent Prevot; Thomas Krey; Markus Schwaninger Published in: reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela, Issue 4, 2021, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22094998 The L‐α‐lysophosphatidylinositol/GPR55 system induces the development of non‐alcoholic steatosis and steatohepatitis Author(s): Marcos F. Fondevila, Uxia Fernandez, Maria J. Gonzalez‐Rellan, Natalia Da Silva Lima, Xabier Buque, Agueda Gonzalez‐Rodriguez, Cristina Alonso, Marta Iruarrizaga‐Lejarreta, Teresa C. Delgado, Marta Varela‐Rey, Ana Senra, Vera Garcia‐Outeiral, Eva Novoa, Cristina Iglesias, Begoña Porteiro, Daniel Beiroa, Cintia Folgueira, Marta Tojo, Jorge L. Torres, Lourdes Hernández‐Cosido, Óscar B Published in: Hepatology, 2020, ISSN 0270-9139 Publisher: John Wiley & Sons Inc. DOI: 10.1002/hep.31290 Nicotine’ actions on energy balance: Friend or foe? Author(s): Patricia Seoane-Collazo, Carlos Diéguez, Rubén Nogueiras, Kamal Rahmouni, José Manuel Fernández-Real, Miguel López Published in: Pharmacology & Therapeutics, 2020, Page(s) 107693, ISSN 0163-7258 Publisher: Pergamon Press DOI: 10.1016/j.pharmthera.2020.107693 Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice Author(s): Jan Wenzel, Cathrin E. Hansen, Carla Bettoni, Miriam A. Vogt, Beate Lembrich, Rentsenkhand Natsagdorj, Gianna Huber, Josefine Brands, Kjestine Schmidt, Julian C. Assmann, Ines Stölting, Kathrin Saar, Jan Sedlacik, Jens Fiehler, Peter Ludewig, Michael Wegmann, Nina Feller, Marius Richter, Helge Müller-Fielitz, Thomas Walther, Gabriele M. König, Evi Kostenis, Walter Raasch, Norbert Hübner, Peter Published in: Proceedings of the National Academy of Sciences, Issue 117/3, 2020, Page(s) 1753-1761, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.1073/pnas.1907467117 Hypothalamic bile acid-TGR5 signaling protects from obesity Author(s): Ashley Castellanos-Jankiewicz, Omar Guzmán-Quevedo, Valérie S. Fénelon, Philippe Zizzari, Carmelo Quarta, Luigi Bellocchio, Anne Tailleux, Julie Charton, Daniela Fernandois, Marcus Henricsson, Catherine Piveteau, Vincent Simon, Camille Allard, Sandrine Quemener, Valentine Guinot, Nathalie Hennuyer, Alessia Perino, Alexia Duveau, Marlène Maitre, Thierry Leste-Lasserre, Samantha Clark, Nathalie Published in: Cell Metabolism, 2021, ISSN 1550-4131 Publisher: Cell Press DOI: 10.1016/j.cmet.2021.04.009 Endogenous THBD (Thrombomodulin) Mediates Angiogenesis in the Ischemic Brain Author(s): Jan Wenzel, Dimitrios Spyropoulos, Julian Christopher Assmann, Mahtab Ahmad Khan, Ines Stölting, Beate Lembrich, Sara Kreißig, Dirk Andreas Ridder, Berend Isermann, Markus Schwaninger Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ISSN 1079-5642 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/atvbaha.120.315061 Multifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis. Author(s): Omar Al-Massadi, Carlos Dieguez, Marc Schneeberger, Miguel López, Markus Schwaninger, Vincent Prevot, Ruben Nogueiras Published in: Nat Rev Endocrinol ., Issue 2021 Dec;17(12), 2021, Page(s) 745-755, ISSN 1759-5029 Publisher: Nature Publishing Group DOI: 10.1038/s41574-021-00559-1 Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner Author(s): Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco L. Torres-Leal, Brian Y.H. Lam, Ana Senra, Johan Fernø, Alicia García Gómez-Valadés, Markus Schwaninger, Vincent Prevot, Giles Yeo, Marc Claret, Miguel López, Carlos Diéguez, Omar Al-Massadi, Ruben Nogueiras Published in: Redox Biology, Issue 41, 2021, Page(s) 101945, ISSN 2213-2317 Publisher: Elsevier BV DOI: 10.1016/j.redox.2021.101945 Tanycytes in the infundibular nucleus and median eminence and their role in the blood-brain barrier Author(s): Vincent Prevot, Ruben Nogueiras, Markus Schwaninger Published in: Handb Clin Neurol, 2021, ISSN 0072-9752 Publisher: Elsevier Science Inc. DOI: 10.1016/b978-0-12-820107-7.00016-1 Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points Author(s): Marcos F. Fondevila, Maria Mercado-Gómez, Amaia Rodríguez, Maria J. Gonzalez-Rellan, Paula Iruzubieta, Víctor Valentí, Javier Escalada, Markus Schwaninger, Vincent Prevot, Carlos Dieguez, Javier Crespo, Gema Frühbeck, Maria L. Martinez- Chantar, Ruben Nogueiras Published in: Journal of Hepatology, 2020, ISSN 0168-8278 Publisher: Elsevier BV DOI: 10.1016/j.jhep.2020.09.027 Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis Author(s): Qiang Yu, Igor Gamayun, Philipp Wartenberg, Qian Zhang, Sen Qiao, Soumya Kusumakshi, Sarah Candlish, Viktoria Götz, Shuping Wen, Debajyoti Das, Amanda Wyatt, Vanessa Wahl, Fabien Ectors, Kathrin Kattler, Daniela Yildiz, Vincent Prevot, Markus Schwaninger, Gaetan Ternier, Paolo Giacobini Philippe Ciofi, Timo D Müller, Ulrich Boehm Published in: Nat Commun ., Issue 2023 Mar 22;14(1):1588, 2023, ISSN 2041-1723 Publisher: Nature Publishing Group MCH Neurons Regulate Permeability of the Median Eminence Barrier Author(s): Hong Jiang, Sarah Gallet, Paul Klemm, Pia Scholl, Kat Folz-Donahue, Janine Altmüller, Jens Alber, Christian Heilinger, Christian Kukat, Anne Loyens, Helge Müller-Fielitz, Sivaraj Sundaram, Markus Schwaninger, Vincent Prevot, Jens C. Brüning Published in: Neuron, Issue 107/2, 2020, Page(s) 306-319.e9, ISSN 0896-6273 Publisher: Cell Press DOI: 10.1016/j.neuron.2020.04.020 Central nicotine induces browning through hypothalamic κ opioid receptor Author(s): Patricia Seoane-Collazo, Laura Liñares-Pose, Eva Rial-Pensado, Amparo Romero-Picó, José María Moreno-Navarrete, Noelia Martínez-Sánchez, Pablo Garrido-Gil, Ramón Iglesias-Rey, Donald A. Morgan, Naoki Tomasini, Samuel Andrew Malone, Ana Senra, Cintia Folgueira, Gema Medina-Gomez, Tomás Sobrino, José L. Labandeira-García, Rubén Nogueiras, Ana I. Domingos, José-Manuel Fernández-Real, Kam Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-12004-z Parvocellular Oxytocin Neurons and Autism Spectrum Disorders Author(s): Sivaraj Mohana Sundaram, Markus Schwaninger Published in: Trends in Endocrinology and Metabolism, 2021, Page(s) 195-197, ISSN 1043-2760 Publisher: Elsevier BV DOI: 10.1016/j.tem.2021.01.004 MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance Author(s): Omar Al-Massadi, Mar Quiñones, Jerome Clasadonte, René Hernandez-Bautista, Amparo Romero-Picó, Cintia Folgueira, Donald A. Morgan, Imre Kalló, Violeta Heras, Ana Senra, Samuel C. Funderburk, Michael J. Krashes, Yara Souto, Miguel Fidalgo, Serge Luquet, Melissa J. Chee, Monica Imbernon, Daniel Beiroa, Lucía García-Caballero, Rosalia Gallego, Brian Y.H. Lam, Giles Yeo, Miguel Lopez, Zsolt Lipo Published in: Diabetes, Issue 68/12, 2019, Page(s) 2210-2222, ISSN 0012-1797 Publisher: American Diabetes Association DOI: 10.2337/db19-0029 Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21 Author(s): Veronica Pena-Leon, Cintia Folgueira, Silvia Barja-Fernández, Raquel Pérez-Lois, Natália Da Silva Lima, Marion Martin, Violeta Heras, Sara Martinez-Martinez, Paola Valero, Cristina Iglesias, Mannon Duquenne, Omar Al-Massadi, Daniel Beiroa, Yara Souto, Miguel Fidalgo, Rasika Sowmyalakshmi, Diana Guallar, Juan Cunarro, Cecilia Castelao, Ana Senra, Patricia González-Saenz, Rocío Vázquez-Cobela, Published in: Nat Metab ., Issue 2022 Jul;4(7), 2022, Page(s) 901-917, ISSN 2522-5812 Publisher: Nature Portfolio DOI: 10.1038/s42255-022-00602-z Hypothalamic dopamine signalling regulates brown fat thermogenesis Author(s): Cintia Folgueira, Daniel Beiroa, Begoña Porteiro, Manon Duquenne, Emma Puighermanal, Marcos F. Fondevila, Silvia Barja-Fernández, Rosalia Gallego, René Hernández-Bautista, Cecilia Castelao, Ana Senra, Patricia Seoane-Collazo, Noemi Gómez-Lado, Pablo Aguiar, Diana Guallar, Miguel Fidalgo, Amparo Romero-Pico, Roger Adan, Clemence Blouet, Jose Luís Labandeira-García, Françoise Jeanrenaud, Imr Published in: Nature Metabolism, Issue 1/8, 2019, Page(s) 811-829, ISSN 2522-5812 Publisher: Nature DOI: 10.1038/s42255-019-0099-7 Glial cells as integrators of peripheral and central signals in the regulation of energy homeostasis Author(s): Sreekala Nampoothiri, Ruben Nogueiras, Markus Schwaninger, Vincent Prevot Published in: Nat Metab ., Issue 2022 Jul;4(7), 2022, Page(s) 813-825, ISSN 2522-5812 Publisher: Nature Portfolio DOI: 10.1038/s42255-022-00610-z Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis Author(s): Marcos F. Fondevila, Uxia Fernandez, Violeta Heras, Tamara Parracho, Maria J. Gonzalez-Rellan, Eva Novoa, Begoña Porteiro, Cristina Alonso, Rebeca Mayo, Natalia da Silva Lima, Cristina Iglesias, Aveline A. Filliol, Ana Senra, Teresa C. Delgado, Ashwin Woodhoo, Laura Herrero, Dolors Serra, Vincent Prevot, Markus Schwaninger, Miguel López, Ruben Nogueiras Published in: J. Hepatol., Issue Volume 77, Issue 1, July 2022, 2022, Page(s) 15-28, ISSN 0168-8278 Publisher: Elsevier BV DOI: 10.1016/j.jhep.2022.02.003 Book chapters (1) Unveiling the Importance of Tanycytes in the Control of the Dialogue Between the Brain and the Periphery Author(s): Sreekala Nampoothiri, Manon Duquenne, Vincent Prevot Published in: Glial-Neuronal Signaling in Neuroendocrine Systems, Issue 11, 2021, Page(s) 255-284, ISBN 978-3-030-62382-1 Publisher: Springer International Publishing DOI: 10.1007/978-3-030-62383-8_11 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
