Well-Aging and the Tanycytic Control of Health

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function

Autorzy: Natália da Silva Lima, Marcos F Fondevila, Eva Nóvoa, Xabier Buqué, Maria Mercado-Gómez, Sarah Gallet, Maria J González-Rellan, Uxia Fernandez, Anne Loyens, Maria Garcia-Vence, Maria Del Pilar Chantada-Vazquez, Susana B Bravo, Patricia Marañon, Ana Senra, Adriana Escudero, Magdalena Leiva, Diana Guallar, Miguel Fidalgo, Pedro Gomes, Marc Claret, Guadalupe Sabio, Marta Varela-Rey, Teresa C De
Opublikowane w: J. Hepatol., Numer 2022 Jan;76(1, 2022, Strona(/y) 11-24, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2021.09.008

Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome

Autorzy: Eva Rial-Pensado, Oscar Freire-Agulleiro, Marcos Ríos, Deng Fu Guo, Cristina Contreras, Patricia Seoane-Collazo, Sulay Tovar, Rubén Nogueiras, Carlos Diéguez, Kamal Rahmouni, Miguel López
Opublikowane w: Molecular Metabolism, Numer 59, 2024, Strona(/y) 101465, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101465

Activation of Hypothalamic <scp>AMP‐Activated</scp> Protein Kinase Ameliorates Metabolic Complications of Experimental Arthritis

Autorzy: Patricia Seoane‐Collazo, Eva Rial‐Pensado, Ánxela Estévez‐Salguero, Edward Milbank, Lucía García‐Caballero, Marcos Ríos, Laura Liñares‐Pose, Morena Scotece, Rosalía Gallego, José Manuel Fernández‐Real, Rubén Nogueiras, Carlos Diéguez, Oreste Gualillo, Miguel López
Opublikowane w: Arthritis & Rheumatology, Numer 74, 2023, Strona(/y) 212-222, ISSN 2326-5191
Wydawca: Wiley
DOI: 10.1002/art.41950

MS2 and LC libraries for untargeted metabolomics: Enhancing method development and identification confidence

Autorzy: Julica Folberth, Kimberly Begemann, Olaf Jöhren, Markus Schwaninger, Alaa Othman
Opublikowane w: Journal of Chromatography B, Numer 1145, 2020, Strona(/y) 122105, ISSN 1570-0232
Wydawca: Elsevier BV
DOI: 10.1016/j.jchromb.2020.122105

Protocol for simultaneous patch-clamp recording from tanycytes and neurons in living mouse brain slices

Autorzy: Tori Lhomme, Vincent Prévot
Opublikowane w: STAR Protocols, Numer 4, 2025, Strona(/y) 102571, ISSN 2666-1667
Wydawca: Elsevier BV
DOI: 10.1016/j.xpro.2023.102571

Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels.

Autorzy: Erika Cecon, Daniela Fernandois, Nicolas Renault, Caio Fernando Ferreira Coelho, Jan Wenzel, Corentin Bedart, Charlotte Izabelle, Sarah Gallet, Sophie Le Poder, Bernard Klonjkowski, Markus Schwaninger, Vincent Prevot, Julie Dam, Ralf Jockers
Opublikowane w: Cell Mol Life Sci, Numer 2022; 79(7), 2022, Strona(/y) 361, ISSN 1420-682X
Wydawca: Birkhauser Verlag
DOI: 10.1007/s00018-022-04390-3

SF1-specific deletion of the energy sensor AMPKγ2 induces obesity

Autorzy: Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López
Opublikowane w: Molecular Metabolism, Numer 92, 2025, Strona(/y) 102091, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.102091

Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death

Autorzy: Florent Sauve, Sreekala Nampoothiri, Sophie A. Clarke, Daniela Fernandois, Caio Fernando Ferreira Coêlho, Julie Dewisme, Edouard G. Mills, Gaetan Ternier, Ludovica Cotellessa, Cristina Iglesias-Garcia, Helge Mueller-Fielitz, Thibaud Lebouvier, Romain Perbet, Vincent Florent, Marc Baroncini, Ariane Sharif, June Ereño-Orbea, Maria Mercado-Gómez, Asis Palazon, Virginie Mattot, Florence Pasquier, S
Opublikowane w: eBioMedicine, Numer 96, 2024, Strona(/y) 104784, ISSN 2352-3964
Wydawca: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104784

Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency

Autorzy: Sivaraj M Sundaram, Adriana Arrulo Pereira, Helge Müller-Fielitz, Hannes Köpke, Meri De Angelis, Timo D Müller, Heike Heuer, Jakob Körbelin, Markus Krohn, Jens Mittag, Ruben Nogueiras, Vincent Prevot, Markus Schwaninger
Opublikowane w: Brain, 2022, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awac243

Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway

Autorzy: Eva Nóvoa, Natália da Silva Lima, Maria J. Gonzalez-Rellan, Maria D.P. Chantada-Vazquez, Joanne Verheij, Amaia Rodriguez, Eva M. Esquinas-Roman, Marcos F. Fondevila, Mirja Koning, Uxia Fernandez, Alba Cabaleiro, Tamara Parracho, Jose Iglesias-Moure, Samuel Seoane, Begoña Porteiro, Adriana Escudero, Ana Senra, Roman Perez-Fernandez, Miguel López, Miguel Fidalgo, Diana Guallar, Maria L. Martinez
Opublikowane w: Hepatology, Numer 81, 2025, Strona(/y) 1535-1552, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1097/hep.0000000000000930

O-GlcNAcylated p53 in the liver modulates hepatic glucose production

Autorzy: Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Uxia Fernandez, Amaia Rodríguez, Marta Varela-Rey, Christelle Veyrat-Durebex, Samuel Seoane, Ganeko Bernardo, Fernando Lopitz-Otsoa, David Fernández-Ramos, Jon Bilbao, Cristina Iglesias, Eva Novoa, Cristina Ameneiro, Ana Senra, Daniel Beiroa, Juan Cuñarro, Maria DP Chantada-Vazquez, Maria Garcia-Vence, Susana B. Bravo, Natalia Da Silva Lima, Begoñ
Opublikowane w: Nature Communications, Numer 12, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-25390-0

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters

Autorzy: Lou Delval, Aline Hantute-Ghesquier, Valentin Sencio, Jean Michel Flaman, Cyril Robil, Fabiola Silva Angulo, Larissa Lipskaia, Ozmen Çobanoğlu, Anne-Sophie Lacoste, Arnaud Machelart, Adeline Danneels, Mathieu Corbin, Lucie Deruyter, Séverine Heumel, Thierry Idziorek, Karin Séron, Florent Sauve, Antonino Bongiovanni, Vincent Prévot, Isabelle Wolowczuk, Sandrine Belouzard, Jean-Michel Saliou, P
Opublikowane w: Nature Aging, Numer 3, 2023, Strona(/y) 829-845, ISSN 2662-8465
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s43587-023-00442-w

Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G<sub>12/13</sub> Protein‐RhoA Pathway in Neural Progenitor Cells and Tanycytes

Autorzy: Raise Ahmad, Marine Luka, Anne‐Sophie Journe, Sarah Gallet, Alan Hegron, Marcio Do Cruzeiro, Mark J. Millan, Philippe Delagrange, Bernard Masri, Julie Dam, Vincent Prevot, Ralf Jockers
Opublikowane w: Journal of Pineal Research, Numer 77, 2025, ISSN 0742-3098
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jpi.70041

Short regulatory DNA sequences to target brain endothelial cells for gene therapy

Autorzy: Hanna Graßhoff, Helge Müller-Fielitz, Godwin K Dogbevia, Jakob Körbelin, Jacqueline Bannach, Carl MG Vahldieck, Kristina Kusche-Vihrog, Olaf Jöhren, Oliver J Müller, Ruben Nogueiras, Vincent Prevot, Markus Schwaninger
Opublikowane w: J Cereb Blood Flow Metab, Numer 2022 Jan; 42(1), 2022, Strona(/y) 104–120, ISSN 0271-678X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x211039617

Nutritionally induced tanycytic plasticity in the hypothalamus of adult ewes

Autorzy: L.D. Prezotto, J.F. Thorson, V. Prevot, D.A. Redmer, A.T. Grazul-Bilska
Opublikowane w: Domestic Animal Endocrinology, Numer 72, 2023, Strona(/y) 106438, ISSN 0739-7240
Wydawca: Elsevier BV
DOI: 10.1016/j.domaniend.2020.106438

Hepatic p63 regulates glucose metabolism by repressing SIRT1

Autorzy: Maria J Gonzalez-Rellan, Eva Novoa, Natalia da Silva Lima, Amaia Rodriguez, Christelle Veyrat-Durebex, Samuel Seoane, Begoña Porteiro, Marcos F Fondevila, Uxia Fernandez,1 Marta Varela-Rey,6 Ana Senra,1 Cristina Iglesias,1 Adriana Escudero,1 Miguel Fidalgo,1 Diana Guallar,7 Roman Perez-Fernandez,1 Vincent Prevot,8 Markus Schwaninger,9 Miguel López,1,2 Carlos Dieguez,1,2 Roberto Coppari,4,5 Gema
Opublikowane w: Gut, Numer 2023 Mar; 72(3), 2023, Strona(/y) 472–483, ISSN 0017-5749
Wydawca: BMJ Publishing Group
DOI: 10.1136/gutjnl-2021-326620

Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa

Autorzy: Vincent Florent, Marc Baroncini, Patrice Jissendi-Tchofo, Renaud Lopes, Matthieu Vanhoutte, Sowmyalakshmi Rasika, Jean-Pierre Pruvo, Jean Vignau, Stephane Verdun, Jeanette E. Johansen, Marie Pigeyre, Sebastien G. Bouret, Ida A.K. Nilsson, Vincent Prevot
Opublikowane w: Neuroendocrinology, Numer 110, 2025, Strona(/y) 552-562, ISSN 0028-3835
Wydawca: S. Karger AG
DOI: 10.1159/000503147

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters

Autorzy: François Briand, Valentin Sencio, Cyril Robil, Séverine Heumel, Lucie Deruyter, Arnaud Machelart, Johanna Barthelemy, Gemma Bogard, Eik Hoffmann, Fabrice Infanti, Oliver Domenig, Audrey Chabrat, Virgile Richard, Vincent Prévot, Ruben Nogueiras, Isabelle Wolowczuk, Florence Pinet, Thierry Sulpice, François Trottein
Opublikowane w: Viruses, Numer 14, 2025, Strona(/y) 2067, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14092067

Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice

Autorzy: Edward Milbank, Nathalia Dragano, Xavi Vidal-Gómez, Verónica Rivas-Limeres, Pablo Garrido-Gil, Mireille Wertheimer, Sylvain Recoquillon, María P. Pata, José Luis Labandeira-Garcia, Carlos Diéguez, Rubén Nogueiras, M. Carmen Martínez, Ramaroson Andriantsitohaina, Miguel López
Opublikowane w: Metabolism, Numer 139, 2024, Strona(/y) 155350, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/j.metabol.2022.155350

Orally Induced Hyperthyroidism Regulates Hypothalamic AMP-Activated Protein Kinase

Autorzy: Valentina Capelli, Carmen Grijota-Martínez, Nathalia R. V. Dragano, Eval Rial-Pensado, Johan Fernø, Rubén Nogueiras, Jens Mittag, Carlos Diéguez, Miguel López
Opublikowane w: Nutrients, Numer 13, 2024, Strona(/y) 4204, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13124204

Tanycytic transcytosis inhibition disrupts energy balance, glucose homeostasis and cognitive function in male mice

Autorzy: Manon Duquenne, Eleonora Deligia, Cintia Folgueira, Cyril Bourouh, Emilie Caron, Frank Pfrieger, Markus Schwaninger, Ruben Nogueiras, Jean-Sébastien Annicotte, Monica Imbernon, Vincent Prévot
Opublikowane w: Molecular Metabolism, Numer 87, 2024, Strona(/y) 101996, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.101996

κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance

Autorzy: Patricia Seoane-Collazo, Amparo Romero-Picó, Eva Rial-Pensado, Laura Liñares-Pose, Ánxela Estévez-Salguero, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, Miguel López
Opublikowane w: International Journal of Molecular Sciences, Numer 22, 2024, Strona(/y) 1515, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22041515

Neuroprotective effect of small extracellular vesicle-mediated targeting of AMPKα2 in cerebral ischemia

Autorzy: Alberto Ouro, Amanda Rodríguez-Díaz, Tania López-González, Daniel Romaus-Sanjurjo, Ánxela Estévez-Salguero, Ramón Iglesias-Rey, Mariña Rodríguez-Arrizabalaga, Paola Fernández-Sanmartín, Mónica Castro-Mosquera, Manuel Debasa-Mouce, Antía Custodia, Marta Aramburu-Núñez, María Muñoz-González, Pablo Aguiar, Ismael González-García, Marc Schneeberger, Rubén Nogueiras, Carlos Diégue
Opublikowane w: Metabolism, Numer 167, 2025, Strona(/y) 156160, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/j.metabol.2025.156160

Estrogen receptor-α signaling in tanycytes lies at the crossroads of fertility and metabolism

Autorzy: Daniela Fernandois, Mariam Rusidzé, Helge Mueller-Fielitz, Florent Sauve, Eleonora Deligia, Mauro S.B. Silva, Florence Evrard, Aurelio Franco-García, Daniele Mazur, Ines Martinez-Corral, Nathalie Jouy, S. Rasika, Claude-Alain Maurage, Paolo Giacobini, Ruben Nogueiras, Benedicte Dehouck, Markus Schwaninger, Francoise Lenfant, Vincent Prevot
Opublikowane w: Metabolism, Numer 158, 2024, Strona(/y) 155976, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/j.metabol.2024.155976

O-GlcNAcylation: A Sweet Hub in the Regulation of Glucose Metabolism in Health and Disease

Autorzy: Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Carlos Dieguez, Ruben Nogueiras
Opublikowane w: Frontiers in Endocrinology, Numer 13, 2022, ISSN 1664-2392
Wydawca: Frontiers Media SA
DOI: 10.3389/fendo.2022.873513

Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice

Autorzy: Marcos F. Fondevila, Eva Novoa, Uxia Fernandez, Valentina Dorta, Tamara Parracho, Henriette Kreimeyer, Maria Garcia-Vence, Maria P. Chantada-Vazquez, Susana B. Bravo, Begoña Porteiro, Alba Cabaleiro, Mijra Koning, Ana Senra, Yara Souto, Joanne Verheij, Diana Guallar, Miguel Fidalgo, Abraham S. Meijnikman, Natalia da Silva Lima, Carlos Dieguez, Maria J. Gonzalez-Rellan, Ruben Nogueiras
Opublikowane w: Molecular Metabolism, Numer 85, 2024, Strona(/y) 101962, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.101962

Cerebral angiogenesis ameliorates pathological disorders in Nemo -deficient mice with small-vessel disease

Autorzy: Yun Jiang, Kristin Müller, Mahtab A. Khan, Julian C. Assmann, Josephine Lampe, Knut Kilau, Marius Richter, Maximilian Kleint, Dirk A Ridder, Norbert Hübner, Marc Schmidt-Supprian, Jan Wenzel, Markus Schwaninger
Opublikowane w: Journal of Cerebral Blood Flow & Metabolism, Numer 41/2, 2021, Strona(/y) 219-235, ISSN 0271-678X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x20910522

Glial endozepines and energy balance: Old peptides with new tricks

Autorzy: Bruno Lebrun, Manon Barbot, Marie‐Christine Tonon, Vincent Prévot, Jérôme Leprince, Jean‐Denis Troadec
Opublikowane w: Glia, Numer 69, 2023, Strona(/y) 1079-1093, ISSN 0894-1491
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/glia.23927

The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Autorzy: Maria Mercado-Gómez, Endika Prieto-Fernández, Naroa Goikoetxea-Usandizaga, Laura Vila-Vecilla, Mikel Azkargorta, Miren Bravo, Marina Serrano-Maciá, Leire Egia-Mendikute, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, So Young Lee, Alvaro Eguileor Giné, Clàudia Gil-Pitarch, Irene González-Recio, Jorge Simón, Petar Petrov, Ramiro Jover, Luis Alfonso Martínez-Cruz, June Ereño-Orbea, Teresa
Opublikowane w: Communications Biology, Numer 5, 2022, ISSN 2399-3642
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42003-022-03789-9

Glial Endozepines Reverse High-Fat Diet-Induced Obesity by Enhancing Hypothalamic Response to Peripheral Leptin

Autorzy: Florent Guillebaud, Manon Duquenne, Mehdi Djelloul, Clément Pierre, Kevin Poirot, Guenièvre Roussel, Seddik Riad, Damien Lanfray, Fabrice Morin, André Jean, Marie-Christine Tonon, Stéphanie Gaigé, Bruno Lebrun, Michel Dallaporta, Jérôme Leprince, Vincent Prevot, Jean-Denis Troadec
Opublikowane w: Molecular Neurobiology, Numer 57, 2021, Strona(/y) 3307-3333, ISSN 0893-7648
Wydawca: Humana Press, Inc.
DOI: 10.1007/s12035-020-01944-z

Brain JNK and metabolic disease

Autorzy: Rubén Nogueiras, Guadalupe Sabio
Opublikowane w: Diabetologia, Numer 64/2, 2021, Strona(/y) 265-274, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-020-05327-w

Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function

Autorzy: Manon Duquenne, Cintia Folgueira, Cyril Bourouh, Marion Millet, Anisia Silva, Jérôme Clasadonte, Monica Imbernon, Daniela Fernandois, Ines Martinez-Corral, Soumya Kusumakshi, Emilie Caron, S. Rasika, Eleonora Deliglia, Nathalie Jouy, Asturo Oishi, Massimiliano Mazzone, Eric Trinquet, Jan Tavernier, Young-Bum Kim, Stéphane Ory, Ralf Jockers, Markus Schwaninger, Ulrich Boehm, Ruben Nogueiras, Jea
Opublikowane w: Nature Metabolism, 2021, ISSN 2522-5812
Wydawca: Nature Portfolio
DOI: 10.1038/s42255-021-00432-5

Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development

Autorzy: Adrian Coutteau‐Robles, Vincent Prevot, Ariane Sharif
Opublikowane w: Journal of Neuroendocrinology, Numer 35, 2023, Strona(/y) 35(3):e13239, ISSN 0953-8194
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jne.13239

Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function

Autorzy: Maria J. Gonzalez-Rellan, Tamara Parracho, Violeta Heras, Amaia Rodriguez, Marcos F. Fondevila, Eva Novoa, Natalia Lima, Marta Varela-Rey, Ana Senra, Maria D.P. Chantada-Vazquez, Cristina Ameneiro, Ganeko Bernardo, David Fernandez-Ramos, Fernando Lopitz-Otsoa, Jon Bilbao, Diana Guallar, Miguel Fidalgo, Susana Bravo, Carlos Dieguez, Maria L. Martinez-Chantar, Oscar Millet, Jose M. Mato, Markus Schw
Opublikowane w: Molecular Metabolism, Numer 75, 2023, Strona(/y) 101776, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2023.101776

Novel insights into minipuberty and <scp>GnRH</scp>: Implications on neurodevelopment, cognition, and <scp>COVID</scp>‐19 therapeutics

Autorzy: Konstantina Chachlaki, Kevin Le Duc, Laurent Storme, Vincent Prevot
Opublikowane w: Journal of Neuroendocrinology, Numer 36, 2024, ISSN 0953-8194
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jne.13387

Glial control of neuronal function

Autorzy: Vincent Prevot
Opublikowane w: Nature Reviews Endocrinology, Numer 18, 2022, Strona(/y) 195-195, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-022-00640-3

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Autorzy: Valentin Sencio, Arnaud Machelart, Cyril Robil, Nicolas Benech, Eik Hoffmann, Chloé Galbert, Lucie Deryuter, Séverine Heumel, Aline Hantute-Ghesquier, Anne Flourens, Priscille Brodin, Fabrice Infanti, Virgile Richard, Jean Dubuisson, Corinne Grangette, Thierry Sulpice, Isabelle Wolowczuk, Florence Pinet, Vincent Prévot, Sandrine Belouzard, François Briand, Martine Duterque-Coquillaud, Harry So
Opublikowane w: Gut Microbes, Numer 14, 2025, Strona(/y) 14(1):2018900, ISSN 1949-0976
Wydawca: Landes Bioscience
DOI: 10.1080/19490976.2021.2018900

BMP8 and activated brown adipose tissue in human newborns

Autorzy: Adela Urisarri, Ismael González-García, Ánxela Estévez-Salguero, María P. Pata, Edward Milbank, Noemi López, Natalia Mandiá, Carmen Grijota-Martinez, Carlos A. Salgado, Rubén Nogueiras, Carlos Diéguez, Francesc Villarroya, José-Manuel Fernández-Real, María L. Couce, Miguel López
Opublikowane w: Nature Communications, Numer 12, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-25456-z

Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons.

Autorzy: Tori Lhomme; Jerome Clasadonte; Monica Imbernon; Daniela Fernandois; Florent Sauve; Emilie Caron; Natália da Silva Lima; Violeta Heras; Ines Martinez-Corral; Helge Mueller-Fielitz; Sowmyalakshmi Rasika; Markus Schwaninger; Rubén Nogueiras; Vincent Prevot
Opublikowane w: J Clin Invest, Numer 8, 2021, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci140521

Angiocrine polyamine production regulates adiposity

Autorzy: Erika Monelli, Pilar Villacampa, Amaia Zabala-Letona, Anabel Martinez-Romero, Judith Llena, Daniel Beiroa, Leonor Gouveia, Iñigo Chivite, Sebastián Zagmutt, Pau Gama-Perez, Oscar Osorio-Conles, Laia Muixi, Ainara Martinez-Gonzalez, Sandra D. Castillo, Natalia Martín-Martín, Pau Castel, Lorea Valcarcel-Jimenez, Irene Garcia-Gonzalez, Josep A. Villena, Sonia Fernandez-Ruiz, Dolors Serra, Laura H
Opublikowane w: Nature Metabolism, Numer 4, 2022, Strona(/y) 327-343, ISSN 2522-5812
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42255-022-00544-6

NF-κB signaling in tanycytes mediates inflammation-induced anorexia

Autorzy: Mareike Böttcher, Helge Müller-Fielitz, Sivaraj M. Sundaram, Sarah Gallet, Vanessa Neve, Kiseko Shionoya, Adriano Zager, Ning Quan, Xiaoyu Liu, Ruth Schmidt-Ullrich, Ronny Haenold, Jan Wenzel, Anders Blomqvist, David Engblom, Vincent Prevot, Markus Schwaninger
Opublikowane w: Molecular Metabolism, Numer 39, 2020, Strona(/y) 101022, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2020.101022

Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis

Autorzy: Eva Rial-Pensado, Verónica Rivas-Limeres, Carmen Grijota-Martínez, Amanda Rodríguez-Díaz, Valentina Capelli, Olga Barca-Mayo, Rubén Nogueiras, Jens Mittag, Carlos Diéguez, Miguel López
Opublikowane w: Frontiers in Physiology, Numer 13, 2022, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.1017381

Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.

Autorzy: Wineke Bakker; Monica Imbernon; Casper Gravesen Salinas; Daniela Herrera Moro Chao; Rim Hassouna; Chloe Morel; Claire Martin; Caroline Leger; Raphael G.P. Denis; Julien Castel; Andreas Peter; Martin Heni; Walter Maetzler; Heidi Solvang Nielsen; Manon Duquenne; Markus Schwaninger; Sofia Lundh; Wouter Frederic Johan Hogendorf; Giuseppe Gangarossa; Anna Secher; Jacob Hecksher-Sørensen; Thomas Åskov
Opublikowane w: Cell Rep. 41:111698 (2022), Numer 7, 2022, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2022.111698

The Role of Tanycytes in the Hypothalamus-Pituitary-Thyroid Axis and the Possibilities for Their Genetic Manipulation

Autorzy: Helge Müller-Fielitz, Markus Schwaninger
Opublikowane w: Experimental and Clinical Endocrinology & Diabetes, Numer 128/06/07, 2020, Strona(/y) 388-394, ISSN 0947-7349
Wydawca: Johann Ambrosius Barth
DOI: 10.1055/a-1065-1855

The SARS-CoV-2 main protease M-pro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Autorzy: Josephine Lampe; Jan Wenzel; Helge Müller-Fielitz; Kristin Müller; Raphael Schuster; Linlin Zhang; Marietta Zille; Markus Krohn; Ümit Özorhan; Yun Jiang; Vanessa Neve; Anke Fähnrich; Fabian Ott; Sonja Binder; Hauke Busch; Ludovic Collin; Roberto Villasenor; Olaf Jöhren; Hermann Altmeppen; Manolis Pasparakis; Ruben Nogueiras; Vincent Prevot; Rolf Hilgenfeld; Markus Glatzel; Markus Schwaninger
Opublikowane w: Nature neuroscience, Numer 10, 2021, ISSN 1097-6256
Wydawca: Nature Publishing Group
DOI: 10.21203/rs.3.rs-86988/v1

Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance

Autorzy: Nathalia R.V. Dragano, Edward Milbank, Roberta Haddad-Tóvolli, Pablo Garrido-Gil, Eva Nóvoa, Marcos F. Fondevilla, Valentina Capelli, Ariane Maria Zanesco, Carina Solon, Joseane Morari, Leticia Pires, Ánxela Estevez-Salguero, Daniel Beiroa, Ismael González-García, Olga Barca-Mayo, Carlos Diéguez, Ruben Nogueiras, José L. Labandeira-García, Elisabeth Rexen Ulven, Trond Ulven, Marc Claret, L
Opublikowane w: Molecular Metabolism, Numer 79, 2024, Strona(/y) 101840, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2023.101840

Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity?

Autorzy: Elvira S. Sandin; Julica Folberth; Helge Müller-Fielitz; Claus U. Pietrzik; Elisabeth Herold; Thomas E. Willnow; Paul T. Pfluger; Ruben Nogueiras; Vincent Prevot; Thomas Krey; Markus Schwaninger
Opublikowane w: reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela, Numer 4, 2021, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094998

The L‐α‐lysophosphatidylinositol/GPR55 system induces the development of non‐alcoholic steatosis and steatohepatitis

Autorzy: Marcos F. Fondevila, Uxia Fernandez, Maria J. Gonzalez‐Rellan, Natalia Da Silva Lima, Xabier Buque, Agueda Gonzalez‐Rodriguez, Cristina Alonso, Marta Iruarrizaga‐Lejarreta, Teresa C. Delgado, Marta Varela‐Rey, Ana Senra, Vera Garcia‐Outeiral, Eva Novoa, Cristina Iglesias, Begoña Porteiro, Daniel Beiroa, Cintia Folgueira, Marta Tojo, Jorge L. Torres, Lourdes Hernández‐Cosido, Óscar B
Opublikowane w: Hepatology, 2020, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.31290

Nicotine’ actions on energy balance: Friend or foe?

Autorzy: Patricia Seoane-Collazo, Carlos Diéguez, Rubén Nogueiras, Kamal Rahmouni, José Manuel Fernández-Real, Miguel López
Opublikowane w: Pharmacology & Therapeutics, 2020, Strona(/y) 107693, ISSN 0163-7258
Wydawca: Pergamon Press
DOI: 10.1016/j.pharmthera.2020.107693

Regulation of Thyroid Hormone Gatekeepers by Thyrotropin in Tanycytes

Autorzy: Akila Chandrasekar, Paula Marie Schmidtlein, Vanessa Neve, Manon Rivagorda, Frauke Spiecker, Karine Gauthier, Vincent Prevot, Markus Schwaninger, Helge Müller-Fielitz
Opublikowane w: Thyroid®, Numer 34, 2024, Strona(/y) 261-273, ISSN 1050-7256
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2023.0375

Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice

Autorzy: Jan Wenzel, Cathrin E. Hansen, Carla Bettoni, Miriam A. Vogt, Beate Lembrich, Rentsenkhand Natsagdorj, Gianna Huber, Josefine Brands, Kjestine Schmidt, Julian C. Assmann, Ines Stölting, Kathrin Saar, Jan Sedlacik, Jens Fiehler, Peter Ludewig, Michael Wegmann, Nina Feller, Marius Richter, Helge Müller-Fielitz, Thomas Walther, Gabriele M. König, Evi Kostenis, Walter Raasch, Norbert Hübner, Peter
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 117/3, 2020, Strona(/y) 1753-1761, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1907467117

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism

Autorzy: María J. Gonzalez-Rellan, Uxía Fernández, Tamara Parracho, Eva Novoa, Marcos F. Fondevila, Natalia da Silva Lima, Lucía Ramos, Amaia Rodríguez, Marina Serrano-Maciá, Gonzalo Perez-Mejias, Pilar Chantada-Vazquez, Cristina Riobello, Christelle Veyrat-Durebex, Sulay Tovar, Roberto Coppari, Ashwin Woodhoo, Markus Schwaninger, Vincent Prevot, Teresa C. Delgado, Miguel Lopez, Antonio Diaz-Quintana
Opublikowane w: Cell Metabolism, Numer 35, 2023, Strona(/y) 1630-1645.e5, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2023.07.003

Hypothalamic bile acid-TGR5 signaling protects from obesity

Autorzy: Ashley Castellanos-Jankiewicz, Omar Guzmán-Quevedo, Valérie S. Fénelon, Philippe Zizzari, Carmelo Quarta, Luigi Bellocchio, Anne Tailleux, Julie Charton, Daniela Fernandois, Marcus Henricsson, Catherine Piveteau, Vincent Simon, Camille Allard, Sandrine Quemener, Valentine Guinot, Nathalie Hennuyer, Alessia Perino, Alexia Duveau, Marlène Maitre, Thierry Leste-Lasserre, Samantha Clark, Nathalie
Opublikowane w: Cell Metabolism, 2021, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2021.04.009

Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits

Autorzy: S. Rasika, Ruben Nogueiras, Markus Schwaninger, Vincent Prevot
Opublikowane w: Nature Reviews Endocrinology, Numer 20, 2024, Strona(/y) 189-190, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-024-00955-3

The hypothalamic–pituitary–gonadal axis and the enigma of Alzheimer disease sex differences

Autorzy: Florent Sauvé, Loïc Kacimi, Vincent Prévot
Opublikowane w: Nature Reviews Endocrinology, Numer 20, 2024, Strona(/y) 317-318, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-024-00981-1

Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway

Autorzy: Amparo Romero-Picó, Marta G. Novelle, Omar Al-Massadi, Daniel Beiroa, Marta Tojo, Violeta Heras, Francisco Ruiz-Pino, Ana Senra, Miguel López, Clemence Blouet, Manuel Tena-Sempere, Rubén Nogueiras, Carlos Diéguez
Opublikowane w: International Journal of Molecular Sciences, Numer 23, 2024, Strona(/y) 3118, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23063118

Endogenous THBD (Thrombomodulin) Mediates Angiogenesis in the Ischemic Brain

Autorzy: Jan Wenzel, Dimitrios Spyropoulos, Julian Christopher Assmann, Mahtab Ahmad Khan, Ines Stölting, Beate Lembrich, Sara Kreißig, Dirk Andreas Ridder, Berend Isermann, Markus Schwaninger
Opublikowane w: Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ISSN 1079-5642
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.120.315061

Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone

Autorzy: Cristina Luongo, Lucile Butruille, Anthony Sébillot, Karine Le Blay, Markus Schwaninger, Heike Heuer, Barbara A. Demeneix, Sylvie Remaud
Opublikowane w: Stem Cell Reports, Numer 16, 2022, Strona(/y) 337-353, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2020.12.009

COVID-19 could worsen cerebral amyloid angiopathy

Autorzy: Julie Dewisme, Thibaud Lebouvier, Quentin Vannod-Michel, null null, Vincent Prevot, Claude-Alain Maurage
Opublikowane w: Journal of Neuropathology & Experimental Neurology, Numer 82, 2024, Strona(/y) 814-817, ISSN 0022-3069
Wydawca: American Association of Neuropathologists, Inc.
DOI: 10.1093/jnen/nlad049

The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes

Autorzy: Sina Rhein, Riccardo Costalunga, Julica Inderhees, Tammo Gürtzgen, Teresa Christina Faupel, Zaib Shaheryar, Adriana Arrulo Pereira, Alaa Othman, Kimberly Begemann, Sonja Binder, Ines Stölting, Valentina Dorta, Peter P. Nawroth, Thomas Fleming, Konrad Oexle, Vincent Prevot, Ruben Nogueiras, Svenja Meyhöfer, Sebastian M. Meyhöfer, Markus Schwaninger
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-50089-3

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner

Autorzy: Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco L. Torres-Leal, Brian Y.H. Lam, Ana Senra, Johan Fernø, Alicia García Gómez-Valadés, Markus Schwaninger, Vincent Prevot, Giles Yeo, Marc Claret, Miguel López, Carlos Diéguez, Omar Al-Massadi, Ruben Nogueiras
Opublikowane w: Redox Biology, Numer 41, 2021, Strona(/y) 101945, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/j.redox.2021.101945

Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis

Autorzy: Steffen Mayerl, Andrea Alcaide Martin, Reinhard Bauer, Markus Schwaninger, Heike Heuer, Charles ffrench-Constant
Opublikowane w: Cells, Numer 11, 2025, Strona(/y) 524, ISSN 2073-4409
Wydawca: MDPI AG
DOI: 10.3390/cells11030524

Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis

Autorzy: Qiang Yu, Igor Gamayun, Philipp Wartenberg, Qian Zhang, Sen Qiao, Soumya Kusumakshi, Sarah Candlish, Viktoria Götz, Shuping Wen, Debajyoti Das, Amanda Wyatt, Vanessa Wahl, Fabien Ectors, Kathrin Kattler, Daniela Yildiz, Vincent Prevot, Markus Schwaninger, Gaetan Ternier, Paolo Giacobini Philippe Ciofi, Timo D Müller, Ulrich Boehm
Opublikowane w: Nat Commun ., Numer 2023 Mar 22;14(1):1588, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-37099-3

Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra’s seminal work

Autorzy: Greg M. Anderson, Jennifer W. Hill, Ursula B. Kaiser, Victor M. Navarro, Ken K. Ong, John R. B. Perry, Vincent Prevot, Manuel Tena-Sempere, Carol F. Elias
Opublikowane w: Nature Reviews Endocrinology, Numer 20, 2024, Strona(/y) 111-123, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-023-00919-z

MCH Neurons Regulate Permeability of the Median Eminence Barrier

Autorzy: Hong Jiang, Sarah Gallet, Paul Klemm, Pia Scholl, Kat Folz-Donahue, Janine Altmüller, Jens Alber, Christian Heilinger, Christian Kukat, Anne Loyens, Helge Müller-Fielitz, Sivaraj Sundaram, Markus Schwaninger, Vincent Prevot, Jens C. Brüning
Opublikowane w: Neuron, Numer 107/2, 2020, Strona(/y) 306-319.e9, ISSN 0896-6273
Wydawca: Cell Press
DOI: 10.1016/j.neuron.2020.04.020

Central nicotine induces browning through hypothalamic κ opioid receptor

Autorzy: Patricia Seoane-Collazo, Laura Liñares-Pose, Eva Rial-Pensado, Amparo Romero-Picó, José María Moreno-Navarrete, Noelia Martínez-Sánchez, Pablo Garrido-Gil, Ramón Iglesias-Rey, Donald A. Morgan, Naoki Tomasini, Samuel Andrew Malone, Ana Senra, Cintia Folgueira, Gema Medina-Gomez, Tomás Sobrino, José L. Labandeira-García, Rubén Nogueiras, Ana I. Domingos, José-Manuel Fernández-Real, Kam
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-12004-z

Nesfatin-1 decreases the motivational and rewarding value of food

Autorzy: Riccardo Dore, Regina Krotenko, Jan Philipp Reising, Luca Murru, Sivaraj Mohana Sundaram, Alessandro Di Spiezio, Helge Müller-Fielitz, Markus Schwaninger, Olaf Jöhren, Jens Mittag, Maria Passafaro, Marya Shanabrough, Tamas L. Horvath, Carla Schulz, Hendrik Lehnert
Opublikowane w: Neuropsychopharmacology, Numer 45, 2021, Strona(/y) 1645-1655, ISSN 0893-133X
Wydawca: Nature Publishing Group
DOI: 10.1038/s41386-020-0682-3

Parvocellular Oxytocin Neurons and Autism Spectrum Disorders

Autorzy: Sivaraj Mohana Sundaram, Markus Schwaninger
Opublikowane w: Trends in Endocrinology and Metabolism, 2021, Strona(/y) 195-197, ISSN 1043-2760
Wydawca: Elsevier BV
DOI: 10.1016/j.tem.2021.01.004

A functional cerebral endothelium is necessary to protect against cognitive decline

Autorzy: Lianne J Trigiani, Miled Bourourou, María Lacalle-Aurioles, Clotilde Lecrux, Amy Hynes, Shoshana Spring, Darren J Fernandes, John G Sled, Frédéric Lesage, Markus Schwaninger, Edith Hamel
Opublikowane w: Journal of Cerebral Blood Flow & Metabolism, Numer 42, 2025, Strona(/y) 74-89, ISSN 0271-678X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x211045438

Multifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis

Autorzy: Omar Al-Massadi, Carlos Dieguez, Marc Schneeberger, Miguel López, Markus Schwaninger, Vincent Prevot, Ruben Nogueiras
Opublikowane w: Nature Reviews Endocrinology, Numer 17, 2022, Strona(/y) 745-755, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-021-00559-1

Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK

Autorzy: Angela Fraga, Eva Rial-Pensado, Rubén Nogueiras, Johan Fernø, Carlos Diéguez, Emilio Gutierrez, Miguel López
Opublikowane w: Frontiers in Endocrinology, Numer 12, 2021, ISSN 1664-2392
Wydawca: Frontiers Media SA
DOI: 10.3389/fendo.2021.669980

Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR

Autorzy: Joanna Kosinska, Julian C Assmann, Julica Inderhees, Helge Müller-Fielitz, Kristian Händler, Sven Geisler, Axel Künstner, Hauke Busch, Anna Worthmann, Joerg Heeren, Christian Sadik, Matthias Gunzer, Vincent Prévot, Ruben Nogueiras, Misa Hirose, Malte Spielmann, Stefan Offermanns, Nina Wettschureck, Markus Schwaninger
Opublikowane w: eLife, Numer 14, 2025, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.98970

Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions

Autorzy: Monica Imbernon, Chiara Saponaro, Hans Christian Cederberg Helms, Manon Duquenne, Daniela Fernandois, Eleonora Deligia, Raphael G.P. Denis, Daniela Herrera Moro Chao, Sowmyalakshmi Rasika, Bart Staels, François Pattou, Frank W. Pfrieger, Birger Brodin, Serge Luquet, Caroline Bonner, Vincent Prevot
Opublikowane w: Cell Metabolism, Numer 34, 2024, Strona(/y) 1054-1063.e7, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2022.06.002

GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells

Autorzy: Natália da Silva Lima, Alba Cabaleiro, Eva Novoa, Cristina Riobello, Patrick J. Knerr, Yantao He, Eva M. Esquinas-Román, Ismael González-García, Vincent Prevot, Markus Schwaninger, Carlos Dieguez, Miguel López, Timo D. Müller, Marta Varela-Rey, Jonathan D. Douros, Ruben Nogueiras
Opublikowane w: Cellular and Molecular Life Sciences, Numer 81, 2024, ISSN 1420-682X
Wydawca: Birkhauser Verlag
DOI: 10.1007/s00018-024-05507-6

MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance

Autorzy: Omar Al-Massadi, Mar Quiñones, Jerome Clasadonte, René Hernandez-Bautista, Amparo Romero-Picó, Cintia Folgueira, Donald A. Morgan, Imre Kalló, Violeta Heras, Ana Senra, Samuel C. Funderburk, Michael J. Krashes, Yara Souto, Miguel Fidalgo, Serge Luquet, Melissa J. Chee, Monica Imbernon, Daniel Beiroa, Lucía García-Caballero, Rosalia Gallego, Brian Y.H. Lam, Giles Yeo, Miguel Lopez, Zsolt Lipo
Opublikowane w: Diabetes, Numer 68/12, 2019, Strona(/y) 2210-2222, ISSN 0012-1797
Wydawca: American Diabetes Association
DOI: 10.2337/db19-0029

A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons

Autorzy: Laura Kuczynski-Noyau, Sixtine Karmann, Paolo Alberton, Ines Martinez-Corral, Sreekala Nampoothiri, Florent Sauvé, Tori Lhomme, Carmelo Quarta, Suneel S. Apte, Sébastien Bouret, Attila Aszodi, Sowmyalakshmi Rasika, Philippe Ciofi, Julie Dam, Vincent Prévot, Virginie Mattot
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-50798-9

Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21

Autorzy: Veronica Pena-Leon, Cintia Folgueira, Silvia Barja-Fernández, Raquel Pérez-Lois, Natália Da Silva Lima, Marion Martin, Violeta Heras, Sara Martinez-Martinez, Paola Valero, Cristina Iglesias, Mannon Duquenne, Omar Al-Massadi, Daniel Beiroa, Yara Souto, Miguel Fidalgo, Rasika Sowmyalakshmi, Diana Guallar, Juan Cunarro, Cecilia Castelao, Ana Senra, Patricia González-Saenz, Rocío Vázquez-Cobela,
Opublikowane w: Nat Metab ., Numer 2022 Jul;4(7), 2022, Strona(/y) 901-917, ISSN 2522-5812
Wydawca: Nature Portfolio
DOI: 10.1038/s42255-022-00602-z

Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms

Autorzy: Maia Uriarte, Pablo N. De Francesco, Gimena Fernández, Daniel Castrogiovanni, Micaela D'Arcangelo, Mónica Imbernon, Sonia Cantel, Severine Denoyelle, Jean-Alain Fehrentz, Jeppe Praetorius, Vincent Prevot, Mario Perello
Opublikowane w: Molecular and Cellular Endocrinology, Numer 538, 2023, Strona(/y) 111449, ISSN 0303-7207
Wydawca: Elsevier BV
DOI: 10.1016/j.mce.2021.111449

Hypothalamic dopamine signalling regulates brown fat thermogenesis

Autorzy: Cintia Folgueira, Daniel Beiroa, Begoña Porteiro, Manon Duquenne, Emma Puighermanal, Marcos F. Fondevila, Silvia Barja-Fernández, Rosalia Gallego, René Hernández-Bautista, Cecilia Castelao, Ana Senra, Patricia Seoane-Collazo, Noemi Gómez-Lado, Pablo Aguiar, Diana Guallar, Miguel Fidalgo, Amparo Romero-Pico, Roger Adan, Clemence Blouet, Jose Luís Labandeira-García, Françoise Jeanrenaud, Imr
Opublikowane w: Nature Metabolism, Numer 1/8, 2019, Strona(/y) 811-829, ISSN 2522-5812
Wydawca: Nature
DOI: 10.1038/s42255-019-0099-7

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Autorzy: Aileen A. Ren, Daniel A. Snellings, Yourong S. Su, Courtney C. Hong, Marco Castro, Alan T. Tang, Matthew R. Detter, Nicholas Hobson, Romuald Girard, Sharbel Romanos, Rhonda Lightle, Thomas Moore, Robert Shenkar, Christian Benavides, M. Makenzie Beaman, Helge Müller-Fielitz, Mei Chen, Patricia Mericko, Jisheng Yang, Derek C. Sung, Michael T. Lawton, J. Michael Ruppert, Markus Schwaninger, Jakob K
Opublikowane w: Nature, Numer 594, 2023, Strona(/y) 271-276, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-021-03562-8

p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway

Autorzy: Marcos F. Fondevila, Eva Novoa, Maria J. Gonzalez-Rellan, Uxia Fernandez, Violeta Heras, Begoña Porteiro, Tamara Parracho, Valentina Dorta, Cristina Riobello, Natalia da Silva Lima, Samuel Seoane, Maria Garcia-Vence, Maria P. Chantada-Vazquez, Susana B. Bravo, Ana Senra, Magdalena Leiva, Miguel Marcos, Guadalupe Sabio, Roman Perez-Fernandez, Carlos Dieguez, Vincent Prevot, Markus Schwaninger, Ash
Opublikowane w: Cell Reports Medicine, Numer 5, 2024, Strona(/y) 101401, ISSN 2666-3791
Wydawca: Elsevier BV
DOI: 10.1016/j.xcrm.2024.101401

The polygamous GnRH neuron: Astrocytic and tanycytic communication with a neuroendocrine neuronal population

Autorzy: Vincent Prevot, Ariane Sharif
Opublikowane w: Journal of Neuroendocrinology, Numer 34, 2023, ISSN 0953-8194
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jne.13104

Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males

Autorzy: Lucile Butruille, Martine Batailler, Marie-Line Cateau, Ariane Sharif, Valérie Leysen, Vincent Prévot, Pascal Vaudin, Delphine Pillon, Martine Migaud
Opublikowane w: Frontiers in Endocrinology, Numer 13, 2022, ISSN 1664-2392
Wydawca: Frontiers Media SA
DOI: 10.3389/fendo.2022.869019

Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice

Autorzy: Ludovica Cotellessa, Veronica Sobrino, Mauro S.B. Silva, Maxime Delit, Hélène Maitre, Emilie Caron, Gaëtan Ternier, Natalia da Silva Lima, Tori Lhomme, Frank Giton, Andrea Sorrentino, Laura Carraresi, Giovanna Di Nardo, Ruben Nogueiras, Manuel Tena-Sempere, Vincent Prevot, Paolo Giacobini
Opublikowane w: Cell Metabolism, Numer Apr 8:S1550-4131(25)00116-0, 2025, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2025.03.013

Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity

Autorzy: Marta Porniece Kumar, Anna Lena Cremer, Paul Klemm, Lukas Steuernagel, Sivaraj Sundaram, Alexander Jais, A. Christine Hausen, Jenkang Tao, Anna Secher, Thomas Åskov Pedersen, Markus Schwaninger, F. Thomas Wunderlich, Bradford B. Lowell, Heiko Backes, Jens C. Brüning
Opublikowane w: Nature Metabolism, Numer 3, 2022, Strona(/y) 1662-1679, ISSN 2522-5812
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42255-021-00499-0

Astrogenesis in the hypothalamus: A life-long process contributing to the development and plasticity of neuroendocrine networks

Autorzy: Ariane Sharif, Vincent Prevot
Opublikowane w: Frontiers in Neuroendocrinology, Numer 75, 2024, Strona(/y) 101154, ISSN 0091-3022
Wydawca: Academic Press
DOI: 10.1016/j.yfrne.2024.101154

Rapid modulation of gut microbiota composition by hypothalamic circuits in mice

Autorzy: Míriam Toledo, Sara Martínez-Martínez, Matthias Van Hul, Berta Laudo, Elena Eyre, Rudy Pelicaen, Anthony Puel, Jordi Altirriba, Alicia G. Gómez-Valadés, Julica Inderhees, Isabel Moreno-Indias, Macarena Pozo, Iñigo Chivite, Maria Milà-Guasch, Roberta Haddad-Tóvolli, Arnaud Obri, Júlia Fos-Domènech, Iasim Tahiri, Sergio R. Llana, Sara Ramírez, Erika Monelli, Markus Schwaninger, Patrice D.
Opublikowane w: Nature Metabolism, Numer Apr 22, 2025, ISSN 2522-5812
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42255-025-01280-3

Serum Metabolites as Potential Markers and Predictors of Depression-like Behavior and Effective Fluoxetine Treatment in Chronically Socially Isolated Rats

Autorzy: Dragana Filipović, Julica Inderhees, Alexandra Korda, Predrag Tadić, Markus Schwaninger, Dragoš Inta, Stefan Borgwardt
Opublikowane w: Metabolites, Numer 14, 2025, Strona(/y) 405, ISSN 2218-1989
Wydawca: MDPI AG
DOI: 10.3390/metabo14080405

Glial cells as integrators of peripheral and central signals in the regulation of energy homeostasis

Autorzy: Sreekala Nampoothiri, Ruben Nogueiras, Markus Schwaninger, Vincent Prevot
Opublikowane w: Nat Metab ., Numer 2022 Jul;4(7), 2022, Strona(/y) 813-825, ISSN 2522-5812
Wydawca: Nature Portfolio
DOI: 10.1038/s42255-022-00610-z

A brainstem–hypothalamus neuronal circuit reduces feeding upon heat exposure

Autorzy: Marco Benevento, Alán Alpár, Anna Gundacker, Leila Afjehi, Kira Balueva, Zsofia Hevesi, János Hanics, Sabah Rehman, Daniela D. Pollak, Gert Lubec, Peer Wulff, Vincent Prevot, Tamas L. Horvath, Tibor Harkany
Opublikowane w: Nature, Numer 628, 2024, Strona(/y) 826-834, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-024-07232-3

Hypothalamic SIRT1-mediated regulation of the hormonal trigger of ovulation and its repression in energy deficit

Autorzy: María J. Vazquez, Silvia Daza-Dueñas, Inmaculada Velasco, Francisco Ruiz-Pino, María J. Sanchez-Tapia, María Manfredi-Lozano, Carmen Torres-Granados, Alexia Barroso, Juan Roa, Miguel A. Sánchez-Garrido, Carlos Dieguez, Alejandro Lomniczi, Rubén Nogueiras, Manuel Tena-Sempere
Opublikowane w: Metabolism, Numer 164, 2025, Strona(/y) 156125, ISSN 0026-0495
Wydawca: Elsevier BV
DOI: 10.1016/j.metabol.2024.156125

Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism

Autorzy: Cristina García-Cáceres, Eglantine Balland, Vincent Prevot, Serge Luquet, Stephen C. Woods, Marco Koch, Tamas L. Horvath, Chun-Xia Yi, Julia A. Chowen, Alexei Verkhratsky, Alfonso Araque, Ingo Bechmann, Matthias H. Tschöp
Opublikowane w: Nature Neuroscience, Numer 22, 2023, Strona(/y) 7-14, ISSN 1097-6256
Wydawca: Nature Publishing Group
DOI: 10.1038/s41593-018-0286-y

Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis

Autorzy: Marcos F. Fondevila, Uxia Fernandez, Violeta Heras, Tamara Parracho, Maria J. Gonzalez-Rellan, Eva Novoa, Begoña Porteiro, Cristina Alonso, Rebeca Mayo, Natalia da Silva Lima, Cristina Iglesias, Aveline A. Filliol, Ana Senra, Teresa C. Delgado, Ashwin Woodhoo, Laura Herrero, Dolors Serra, Vincent Prevot, Markus Schwaninger, Miguel López, Ruben Nogueiras
Opublikowane w: J. Hepatol., Numer Volume 77, Numer 1, July 2022, 2022, Strona(/y) 15-28, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2022.02.003

MECHANISMS IN ENDOCRINOLOGY: The gut–brain axis: regulating energy balance independent of food intake

Autorzy: Ruben Nogueiras
Opublikowane w: European Journal of Endocrinology, Numer 185, 2023, Strona(/y) R75-R91, ISSN 0804-4643
Wydawca: BioScientifica Ltd.
DOI: 10.1530/eje-21-0277

Bridging brain barriers for gene therapy

Autorzy: Markus Schwaninger, Vincent Prevot, Ruben Nogueiras
Opublikowane w: Open Access Government, Numer 42, 2024, Strona(/y) 210-211, ISSN 2516-3817
Wydawca: Adjacent Digital Politics Ltd
DOI: 10.56367/oag-042-10410

Feed or breed: Hypothalamic mechanisms linking energy availability to puberty onset

Autorzy: Alicia Sicardi, Daniela Fernandois, Vincent Prevot
Opublikowane w: Neuron, Numer 113, 2025, Strona(/y) 968-970, ISSN 0896-6273
Wydawca: Cell Press
DOI: 10.1016/j.neuron.2025.03.012

How COVID-19 affects microvessels in the brain

Autorzy: Jan Wenzel, Markus Schwaninger
Opublikowane w: Brain, 2022, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awac211

Glycemic control: Tanycytes march to the beat of the suprachiasmatic drummer

Autorzy: Monica Imbernon, Benedicte Dehouck, Vincent Prevot
Opublikowane w: Current Biology, Numer 32, 2024, Strona(/y) R173-R176, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2022.01.038

The WATCH project: Tanycytes in health and disease

Autorzy: Vincent Prevot, Markus Schwaninger, Ruben Nogueiras
Opublikowane w: Open Access Government, Numer 37, 2023, Strona(/y) 132-133, ISSN 2516-3817
Wydawca: Adjacent Digital Politics Ltd
DOI: 10.56367/oag-037-10410

Prolonged lactation: Preventing obesity since infancy

Autorzy: Vincent Prevot, Markus Schwaninger, Ruben Nogueiras
Opublikowane w: Open Access Government, Numer 43, 2024, Strona(/y) 106-107, ISSN 2516-3817
Wydawca: Adjacent Digital Politics Ltd
DOI: 10.56367/oag-043-10410

L’IRM hypothalamique, un nouvel outil diagnostique dans l’anorexie mentale ?

Autorzy: Vincent Florent, Marc Baroncini, Vincent Prévot
Opublikowane w: médecine/sciences, Numer 36, 2020, Strona(/y) 115-117, ISSN 0767-0974
Wydawca: Editions E D K
DOI: 10.1051/medsci/2020007

Seasonal biology: Tanycytes give the hypothalamus a spring makeover

Autorzy: Manon Rivagorda, Vincent Prevot, Markus Schwaninger
Opublikowane w: Current Biology, Numer 34, 2025, Strona(/y) R209-R211, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2024.01.055

Food odour recognition adjusts systemic metabolism to nutrient availability

Autorzy: Vincent Prevot, Ruben Nogueiras
Opublikowane w: Nature Reviews Endocrinology, Numer 19, 2023, Strona(/y) 130-131, ISSN 1759-5029
Wydawca: Nature Publishing Group
DOI: 10.1038/s41574-022-00801-4

Sowing SARS-CoV-2 to reap neurodegeneration: A hamster study

Autorzy: S. Rasika, Daniela Fernandois, Vincent Prévot
Opublikowane w: eBioMedicine, Numer 80, 2022, Strona(/y) 104071, ISSN 2352-3964
Wydawca: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104071

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points

Autorzy: Marcos F. Fondevila, Maria Mercado-Gómez, Amaia Rodríguez, Maria J. Gonzalez-Rellan, Paula Iruzubieta, Víctor Valentí, Javier Escalada, Markus Schwaninger, Vincent Prevot, Carlos Dieguez, Javier Crespo, Gema Frühbeck, Maria L. Martinez- Chantar, Ruben Nogueiras
Opublikowane w: Journal of Hepatology, 2020, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2020.09.027

Brain infection by SARS-CoV-2: Lifelong consequences

Autorzy: Vincent Prévot
Opublikowane w: Open Access Government, Numer 41, 2024, Strona(/y) 22-23, ISSN 2516-3817
Wydawca: Adjacent Digital Politics Ltd
DOI: 10.56367/oag-041-10397

Les neurones produisant l’hormone de mélano-concentration régulent la fenestration des anses vasculaires de l’éminence médiane

Autorzy: Alicia Sicardi, Vincent Prévot
Opublikowane w: médecine/sciences, Numer 38, 2022, Strona(/y) 248-251, ISSN 0767-0974
Wydawca: Editions E D K
DOI: 10.1051/medsci/2022016

Les neurones produisant la gonadolibérine sculptent leur environnement neuroglial dans la petite enfance

Autorzy: Ariane Sharif, Vincent Prévot
Opublikowane w: médecine/sciences, Numer 38, 2022, Strona(/y) 428-430, ISSN 0767-0974
Wydawca: Editions E D K
DOI: 10.1051/medsci/2022047

Unveiling the Importance of Tanycytes in the Control of the Dialogue Between the Brain and the Periphery

Autorzy: Sreekala Nampoothiri, Manon Duquenne, Vincent Prevot
Opublikowane w: Masterclass in Neuroendocrinology, Glial-Neuronal Signaling in Neuroendocrine Systems, Numer Numer 11, pp 255-284, 2023, Strona(/y) 255-284
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-62383-8_11

Tanycytes in the infundibular nucleus and median eminence and their role in the blood–brain barrier

Autorzy: Vincent Prevot, Ruben Nogueiras, Markus Schwaninger
Opublikowane w: Handbook of Clinical Neurology, The Human Hypothalamus - Middle and Posterior Region, Numer 180:253-273, 2022, Strona(/y) 253-273
Wydawca: Elsevier
DOI: 10.1016/b978-0-12-820107-7.00016-1

Gene therapy targeting the blood-brain barrier

Autorzy: Jakob Körbelin, Adriana Arrulo, Markus Schwaninger
Opublikowane w: Vitamins and Hormones, Blood-Brain Barrier, Numer 126, 2024, Strona(/y) 191-217
Wydawca: Elsevier
DOI: 10.1016/bs.vh.2024.03.001

Wyszukiwanie danych OpenAIRE...

Publikacje

Udostępnij tę stronę Udostępnij tę stronę w mediach społecznościowych

Pobierz Pobierz zawartość strony