Identification and Management of Patients at Risk – Outcome and Vascular Events in Peritoneal Dialysis | IMPROVE-PD | Project | Results | H2020 | CORDIS

Risultati finali

Satellite Training Modules organised (first)
Satellite Training Modules organised (second)
Supervisory Board

Supervisory Board, members list and first plenary session.

Satellite Training Modules organised (third)

Scientific papers in peer reviewed journals for each ESR (at least 2 per ESR) WP3

Scientific papers in peer reviewed journals for each ESR at least 2 per ESR WP3

Scientific papers in peer reviewed journals for each ESR (at least 2 per ESR) WP1

Scientific papers in peer reviewed journals for each ESR at least 2 per ESR WP1

Scientific papers in peer reviewed journals for each ESR (at least 2 per ESR) WP2

Scientific papers in peer reviewed journals for each ESR at least 2 per ESR WP2

Guidelines for ITP
IMPROVE PD website and general brochure

Report on cardiovascular complications of infection in animal models and cardiovascular effects of local inflammation and peritoneal response modification
Reports on outreach and dissemination activity (second)

Reports on outreach and dissemination activity second

Reports on outreach and dissemination activity (third)

Reports on outreach and dissemination activity third

Report on competing treatment modalities in patients commencing PD according to baseline risk profile and risk stratification prognostic model for personalized medicine approach in high risk, inflamed PD patients

List of ESRs recruited
Report on mechanisms of inflammatory-immune communication local-systemic

Report on mechanisms of inflammatoryimmune communication localsystemic

Report on markers of inflammation-immunity in response to anti-inflammatory PD additives

Report on markers of inflammationimmunity in response to antiinflammatory PD additives

Reports on outreach and dissemination activity (first)
Report on markers of inflammation-immunity using novel osmotic agents and pathways to improve patient access to anti-inflammatory cardiovascular-protective therapies in PD

Report on markers of inflammationimmunity using novel osmotic agents and pathways to improve patient access to antiinflammatory cardiovascularprotective therapies in PD

Detailed Recruitment Strategy Plan

Pubblicazioni

Understanding Cell Model Characteristics-RNA Expression Profiling in Primary and Immortalized Human Mesothelial Cells, and in Human Vein and Microvascular Endothelial Cells

Autori: Iva Marinovic , Maria Bartosova , Rebecca Herzog, Juan Manuel Sacnun, Conghui Zhang , Robin Hoogenboom , Markus Unterwurzacher , Thilo Hackert , Aurelio A Teleman , Klaus Kratochwill , Claus Peter Schmitt
Pubblicato in: Cells, 2022, ISSN 2073-4409
Editore: Basel: MDPI AG, 2012
DOI: 10.3390/cells11193133

Kidney microRNA Expression Pattern in Type 2 Diabetic Nephropathy in BTBR Ob/Ob Mice

Autori: Lucas Opazo-Ríos 1 2, Antonio Tejera-Muñoz 3, Manuel Soto Catalan 1, Vanessa Marchant 3, Carolina Lavoz 4, Sebastián Mas Fontao 1, Juan Antonio Moreno 5, Marta Fierro Fernandez 6, Ricardo Ramos 7, Beatriz Suarez-Alvarez 8, Carlos López-Larrea 8 9, Marta Ruiz-Ortega 3, Jesús Egido 1, Raúl R Rodrigues-Díez 3 8
Pubblicato in: Frontiers in Pharmacology, Numero Volume 13 - 2022, 2022, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.778776

Proteome-Wide Differential Effects of Peritoneal Dialysis Fluid Properties in an In Vitro Human Endothelial Cell Model

Autori: Juan Manuel Sacnun; Robin Hoogenboom; Fabian Eibensteiner; Isabel J. Sobieszek; Markus Unterwurzacher; Anja Wagner; Rebecca Herzog; Klaus Kratochwill
Pubblicato in: International Journal of Molecular Sciences; Volume 23; Numero 14; Pages: 8010, Numero olume 23, Numero 14July 2022, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23148010

An Experimental Workflow for Studying Barrier Integrity, Permeability, and Tight Junction Composition and Localization in a Single Endothelial Cell Monolayer: Proof of Concept.

Autori: Maria Bartosova; David Ridinger; Iva Marinovic; Jana Heigwer; Conghui Zhang; Eszter Levai; Eszter Levai; Jens H Westhoff; Franz Schaefer; Stefan Terjung; Georg Hildenbrand; Damir Krunic; Felix Bestvater; Michael Hausmann; Claus Peter Schmitt; Sotirios G. Zarogiannis; Sotirios G. Zarogiannis
Pubblicato in: International Journal of Molecular Sciences, Numero 2021 Aug; 22(15): 8178., 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22158178

Levels of Procollagen Type I C-Terminal Pro-Peptide and Galectin-3, Arterial Stiffness Measured By Pulse Wave Velocity, and Cardiovascular Morbidity and Mortality in 44 Patients 2 Years After Kidney Transplantation

Autori: Salib, Madonna; Girerd, Nicolas; Simon, Arnaud; Kearney-Schwartz, Anna; Duarte, Kévin; Leroy, Céline; Rossignol, Patrick; Benetos, Athanase; Frimat, Luc; Girerd, Sophie
Pubblicato in: Annals of Transplantation, 2023, ISSN 1425-9524
Editore: International Scientific Information, Inc.
DOI: 10.12659/aot.938137

Off-label use of cinacalcet in pediatric primary hyperparathyroidism: A French multicenter experience

Autori: Julie Bernardor 1 2 3 4, Sacha Flammier 1, Jean-Pierre Salles 5, Cyril Amouroux 6, Mireille Castanet 7, Anne Lienhardt 8, Laetitia Martinerie 9, Ivan Damgov 10 11, Agnès Linglart 12 13, Justine Bacchetta 1 2 14
Pubblicato in: Frontiers in Pediatrics, 2022, ISSN 2296-2360
Editore: Frontiers Media
DOI: 10.3389/fped.2022.926986

Interleukin-17A: Potential mediator and therapeutic target in hypertension.

Autori: Raúl R. Rodrigues-Diez; Antonio Tejera-Muñoz; Macarena Orejudo; Laura Marquez-Exposito; Laura Santos-Sanchez; Sandra Rayego-Mateos; Elena Cantero-Navarro; Lucia Tejedor-Santamaria; Vanessa Marchant; Alberto Ortiz; Jesús Egido; Sergio Mezzano; Rafael Selgas; Juan F. Navarro-González; Jose M. Valdivielso; Carolina Lavoz; Marta Ruiz-Ortega
Pubblicato in: Nefrología (English Edition), Numero Vol 41, Iss 3, Pp 244-257 (2021), 2021, ISSN 0211-6995
Editore: Grupo Aula Medica S.A.
DOI: 10.1016/j.nefroe.2021.06.003

Serum markers of fibrosis, cardiovascular and all-cause mortality in hemodialysis patients: the AURORA trial.

Autori: Madonna Salib; Sophie Girerd; Nicolas Girerd; Winfried März; Hubert Scharnagl; Ziad A. Massy; Céline Leroy; Kevin Duarte; Hallvard Holdaas; Alan G. Jardine; Roland E. Schmieder; Bengt Fellström; Natalia López-Andrés; Patrick Rossignol; Faiez Zannad
Pubblicato in: Clinical Research in Cardiology, 2022, ISSN 1861-0684
Editore: Steinkopff
DOI: 10.1007/s00392-021-01898-9

Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis

Autori: Lucia Tejedor-Santamaria; Jose Luis Morgado-Pascual; Laura Marquez-Exposito; Beatriz Suarez-Alvarez; Raul R. Rodrigues-Diez; Antonio Tejera-Muñoz; Vanessa Marchant; Sergio Mezzano; Carlos Lopez-Larrea; Anna Sola; Gema Maria Fernandez-Juarez; Alberto Ortiz; Sandra Rayego-Mateos; Marta Ruiz-Ortega
Pubblicato in: Pharmaceuticals, 2022, ISSN 1424-8247
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph15020121

Proteomic study of mesothelial and endothelial cross-talk: key lessons

Autori: Juan Manuel Sacnun 1 2, Rebecca Herzog 1 2, Klaus Kratochwill 1 2
Pubblicato in: Expert Review of Proteomics, Numero Jul-Dec;19(7-12):289-296., 2022, ISSN 1478-9450
Editore: Future Drugs Ltd.
DOI: 10.1080/14789450.2023.2174851

Monitoring Daily Ultrafiltration in Automated Peritoneal Dialysis

Autori: Fabian Eibensteiner, Krystell Oviedo Flores, Markus Unterwurzacher, Rebecca Herzog, Klaus Kratochwill, Seth L. Alper, Christoph Aufricht, Franz König, Andreas Vychytil
Pubblicato in: Clin J Am Soc Nephrol., Numero Jan; 17(1): 107–110, 2022, ISSN 1555-9041
Editore: American Society of Nephrology
DOI: 10.2215/cjn.08180621

Assessing mechanical catheter dysfunction in automated tidal peritoneal dialysis using cycler software: a case control, proof-of-concept study.

Autori: Krystell Oviedo Flores; Lukas Kaltenegger; Fabian Eibensteiner; Markus Unterwurzacher; Klaus Kratochwill; Christoph Aufricht; Franz König; Andreas Vychytil
Pubblicato in: Scientific Reports, Numero 2022; 12: 5657., 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-09462-9

Peritoneal transformation shortly after kidney transplantation in pediatric patients with preceding chronic peritoneal dialysis.

Autori: Conghui Zhang, Maria Bartosova, Iva Marinovic, Constantin Schwab, Betti Schaefer, Karel Vondrak, Gema Ariceta, Ariane Zaloszyc, Bruno Ranchin, Christina Taylan, Rainer Büscher, Jun Oh, Arianeb Mehrabi , Claus Peter Schmitt
Pubblicato in: Nephrology Dialysis Transplantation, Numero Feb 8;gfad031, 2023, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfad031

Advances in biodesign: artificial water channels outperforming aquaporins

Autori: Ines P D Costa , Iain A Drummond , Olivier Devuyst
Pubblicato in: Kidney International, Numero 2023 Apr;103(4):651-653., 2023, ISSN 1523-1755
Editore: Nature
DOI: 10.1016/j.kint.2023.01.015

A Meta-Analysis of Human Transcriptomics Data in the Context of Peritoneal Dialysis Identifies Novel Receptor-Ligand Interactions as Potential Therapeutic Targets

Autori: Michail Evgeniou,1 Juan Manuel Sacnun,1,2,3 Klaus Kratochwill,1,2 and Paul Perco4,*
Pubblicato in: Int J Mol Sci., Numero Dec; 22(24): 13277., 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222413277

Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis

Autori: José Luis Morgado-Pascual 1 2, Beatriz Suarez-Alvarez 3 4, Vanessa Marchant 1 3, Pamela Basantes 1 3, Pierre-Louis Tharaux 5, Alberto Ortiz 3 6, Carlos Lopez-Larrea 3 4, Marta Ruiz-Ortega 1 3, Sandra Rayego-Mateos 1 3
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24010486

Lithium preserves peritoneal membrane integrity by suppressing mesothelial cell αB-crystallin.

Autori: Rebecca Herzog; Juan Manuel Sacnun; Guadalupe González-Mateo; Maria Bartosova; Katarzyna Bialas; Anja Wagner; Markus Unterwurzacher; Isabel J. Sobieszek; Lisa Daniel-Fischer; Krisztina Rusai; Lucía Pascual-Antón; Klaus Kaczirek; Andreas Vychytil; Claus Peter Schmitt; Manuel López-Cabrera; Seth L. Alper; Seth L. Alper; Christoph Aufricht; Klaus Kratochwill
Pubblicato in: SCIENCE TRANSLATIONAL MEDICINE, 2021, ISSN 1946-6234
Editore: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aaz9705

Role of Macrophages and Related Cytokines in Kidney Disease

Autori: Elena Cantero-Navarro 1 2, Sandra Rayego-Mateos 1 2, Macarena Orejudo 3 4, Lucía Tejedor-Santamaria 1 2, Antonio Tejera-Muñoz 1 2, Ana Belén Sanz 2 5, Laura Marquez-Exposito 1 2, Vanessa Marchant 1 2, Laura Santos-Sanchez 1 2, Jesús Egido 3 4, Alberto Ortiz 2 5, Teresa Bellon 6, Raúl R Rodrigues-Diez 1 2, Marta Ruiz-Ortega 1 2
Pubblicato in: Frontiers in Medicine, Numero 2021 Jul 8;8:688060, 2021, ISSN 2296-858X
Editore: Lausanne Frontiers Media S.A
DOI: 10.3389/fmed.2021.688060

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis

Autori: Raffaele Strippoli, Pilar Sandoval, Roberto Moreno-Vicente, Lucia Rossi, Cecilia Battistelli, Michela Terri, Lucía Pascual-Antón, Marta Loureiro, Francesca Matteini, Enrique Calvo, José Antonio Jiménez-Heffernan, Manuel José Gómez, Victor Jiménez-Jiménez, Fátima Sánchez-Cabo, Jesús Vázquez, Marco Tripodi, Manuel López-Cabrera, Miguel Ángel del Pozo
Pubblicato in: Cell Death & Disease, Numero 11/8, 2020, ISSN 2041-4889
Editore: Nature Publishing Group
DOI: 10.1038/s41419-020-02822-1

Targeting carcinoma-associated mesothelial cells with antibody-drug conjugates in ovarian carcinomatosis

Autori: Lucía Pascual-Antón, Pilar Sandoval, Guadalupe T González-Mateo, Valeria Kopytina , Henar Tomero-Sanz , Eva María Arriero-País , José Antonio Jiménez-Heffernan , Myriam Fabre , Isabel Egaña , Cristina Ferrer , Laureano Simón , Lucía González-Cortijo , Ricardo Sainz de la Cuesta , Manuel López-Cabrera
Pubblicato in: The Journal of Pathology, 2023, ISSN 0022-3417
Editore: John Wiley & Sons Inc.
DOI: 10.1002/path.6170

Could IL-17A Be a Novel Therapeutic Target in Diabetic Nephropathy?

Autori: Carolina Lavoz; Sandra Rayego-Mateos; Macarena Orejudo; Lucas Opazo-Ríos; Vanessa Marchant; Laura Marquez-Exposito; Antonio Tejera-Muñoz; Juan F. Navarro-González; Alejandra Droguett; Alberto Ortiz; Alberto Ortiz; Jesús Egido; Sergio Mezzano; Raúl R. Rodrigues-Diez; Marta Ruiz-Ortega
Pubblicato in: Journal of Clinical Medicine, Numero 2020 Jan; 9(1): 272., 2020, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9010272

Nutritional Calcium Supply Dependent Calcium Balance, Bone Calcification and Calcium Isotope Ratios in Rats.

Autori: Jeremy Rott 1, Eva Teresa Toepfer 1, Maria Bartosova 1, Ana Kolevica 2, Alexander Heuser 2, Michael Rabe 1, Geert Behets 3, Patrick C D'Haese 3, Viktoria Eichwald 4, Manfred Jugold 4, Ivan Damgov 1, Sotirios G Zarogiannis 1, Rukshana Shroff 5, Anton Eisenhauer 2, Claus Peter Schmitt 1
Pubblicato in: International Journal of molecular Sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23147796

Steviol glycosides as an alternative osmotic agent for peritoneal dialysis fluid

Autori: Valeria Kopytina; Lucía Pascual-Antón; Nora Toggweiler; Eva-María Arriero-País; Lisa Strahl; Patricia Albar-Vizcaíno; David Sucunza; Juan J. Vaquero; Sonja Steppan; Dorothea Piecha; Manuel López-Cabrera; Guadalupe-Tirma González-Mateo
Pubblicato in: Frontiers in Pharmacology, Numero 2022; 13: 868374., 2022, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.868374

Novel Aspects of the Immune Response Involved in the Peritoneal Damage in Chronic Kidney Disease Patients under Dialysis.

Autori: Flavia Trionfetti 1 2, Vanessa Marchant 3 4, Guadalupe T González-Mateo 5 6, Edyta Kawka 7, Laura Márquez-Expósito 3 4, Alberto Ortiz 8, Manuel López-Cabrera 5, Marta Ruiz-Ortega 3 4, Raffaele Strippoli 1 2
Pubblicato in: International Journal of Molecular Sciences, Numero 2023 Mar; 24(6): 5763., 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065763

In-Depth Analysis of the Extracorporeal Proteome Adsorbed to Dialysis Membranes during Hemodialysis

Autori: Daniel-Fischer, Lisa; Sobieszek, Isabel J.; Wagner, Anja; Sacnun, Juan Manuel; Watschinger, Bruno ; Aufricht, Christoph; Kratochwill, Klaus ; Herzog, Rebecca
Pubblicato in: Membranes (Basel)., Numero Nov; 12(11): 1120., 2022, ISSN 2077-0375
Editore: Molecular Diversity Preservation International
DOI: 10.3390/membranes12111120

Encapsulating Peritoneal Sclerosis: Pathophysiology and Current Treatment Options

Autori: Rajesh M. Jagirdar, Andreas Bozikas, Sotirios G. Zarogiannis, Maria Bartosova, Claus Peter Schmitt, Vassilios Liakopoulos
Pubblicato in: International Journal of Molecular Sciences, Numero 20/22, 2019, Pagina/e 5765, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20225765

Alanyl-Glutamine Restores Tight Junction Organization after Disruption by a Conventional Peritoneal Dialysis Fluid

Autori: Maria Bartosova, Rebecca Herzog, David Ridinger, Eszter Levai, Hanna Jenei, Conghui Zhang, Guadalupe T. González Mateo, Iva Marinovic, Thilo Hackert, Felix Bestvater, Michael Hausmann, Manuel López Cabrera, Klaus Kratochwill, Sotirios G. Zarogiannis, Claus Peter Schmitt
Pubblicato in: Biomolecules, Numero 10/8, 2020, Pagina/e 1178, ISSN 2218-273X
Editore: MDPI
DOI: 10.3390/biom10081178

Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes.

Autori: Laura Marquez-Exposito; Laura Marquez-Exposito; Lucia Tejedor-Santamaria; Lucia Tejedor-Santamaria; Laura Santos-Sanchez; Laura Santos-Sanchez; Floris A. Valentijn; Elena Cantero-Navarro; Elena Cantero-Navarro; Sandra Rayego-Mateos; Sandra Rayego-Mateos; Raul R. Rodrigues-Diez; Raul R. Rodrigues-Diez; Antonio Tejera-Muñoz; Antonio Tejera-Muñoz; Vanessa Marchant; Vanessa Marchant; Ana B. Sanz; An
Pubblicato in: Frontiers in Pharmacology, Numero Vol 12 (2021), 2021, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.662020

Angiogenic Role of Mesothelium-Derived Chemokine CXCL1 During Unfavorable Peritoneal Tissue Remodeling in Patients Receiving Peritoneal Dialysis as Renal Replacement Therapy

Autori: Rusan Ali Catar; Maria Bartosova; Edyta Kawka; Lei Chen; Iva Marinovic; Conghui Zhang; Hongfan Zhao; Dashan Wu; Daniel Zickler; Honorata Stadnik; Marek Karczewski; Julian Kamhieh-Milz; Achim Jörres; Achim Jörres; Guido Moll; Guido Moll; Guido Moll; Claus Peter Schmitt; Janusz Witowski; Janusz Witowski
Pubblicato in: Frontiers in Immunology, Numero Vol 13 (2022), 2022, Pagina/e 13: 821681., ISSN 1664-3224
Editore: Lausanne Frontiers Media S.A. 2010-
DOI: 10.3389/fimmu.2022.821681

Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis

Autori: Maria Bartosova, Conghui Zhang, Betti Schaefer, Rebecca Herzog, David Ridinger, Ivan Damgov, Eszter Levai, Iva Marinovic, Christoph Eckert, Philipp Romero, Peter Sallay, Akos Ujszaszi, Markus Unterwurzacher, Anja Wagner, Georg Hildenbrand, Bradley A. Warady, Franz Schaefer, Sotirios G. Zarogiannis, Klaus Kratochwill and Claus Peter Schmitt
Pubblicato in: Circulation Research, 2021, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.121.319310

Peritoneal Dialysis Fluid Supplementation with Alanyl-Glutamine Attenuates Conventional Dialysis Fluid-Mediated Endothelial Cell Injury by Restoring Perturbed Cytoprotective Responses.

Autori: Rebecca Herzog; Maria Bartosova; Silvia Tarantino; Anja Wagner; Markus Unterwurzacher; Juan Manuel Sacnun; Anton Lichtenauer; Lilian Kuster; Betti Schaefer; Seth L. Alper; Seth L. Alper; Christoph Aufricht; Claus Peter Schmitt; Klaus Kratochwill
Pubblicato in: Biomolecules, Numero Volume 10, Numero 12, 2020, Pagina/e Pages 1 - 21, ISSN 2218-273X
Editore: Basel: MDPI AG, 2011
DOI: 10.3390/biom10121678

Anti-Galectin-2 antibody treatment reduces atherosclerotic plaque size and alters macrophage polarity.

Autori: Jamie Kane; M F Jansen; Sebastian Hendrix; Laura A Bosmans; Linda Beckers; Claudia M. van Tiel; Marion J.J. Gijbels; Noam Zelcer; Carlie J.M. de Vries; Philipp von Hundelshausen; Marc Vervloet; Ed Eringa; A.J.G. Horrevoets; Niels van Royen; Esther Lutgens
Pubblicato in: Thrombosis and Haemostasis, Numero VOLUME=122;ISSUE=06, 2022, Pagina/e STARTPAGE=1047;ENDPAGE=1057, ISSN 0340-6245
Editore: Schattauer
DOI: 10.1055/a-1711-1055

Peritoneal Dialysis Vintage and Glucose Exposure but Not Peritonitis Episodes Drive Peritoneal Membrane Transformation During the First Years of PD

Autori: Maria Bartosova, Betti Schaefer, Karel Vondrak, Peter Sallay, Christina Taylan, Rimante Cerkauskiene, Maria Dzierzega, Gordana Milosevski-Lomic, Rainer Büscher, Ariane Zaloszyc, Philipp Romero, Felix Lasitschka, Bradley A. Warady, Franz Schaefer, Akos Ujszaszi, Claus Peter Schmitt
Pubblicato in: Frontiers in Physiology, Numero 10, 2019, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2019.00356

IMPROVE-PD Finder: A Web-Based Platform To Search and Share Peritoneal Dialysis Biobank, Registry and Clinical Trial Metadata.

Autori: Ivan Damgov, Maria Bartosova, Iva Marinovic, Obaida Istanbuly, Meinhard Kieser, Mark Lambie, Simon J. Davies, Claus Peter Schmitt, IMPROVE-PD Consortium (Andreas Vychytil, Anne-Catherine Raby, Chantal Colmont, Cristoph Aufricht, David W. Johnson, Donald Fraser, Ed Eringa, Johann Morelle, Jose M. Valdivielso, Klaus Kratochwill, Lily Jakulj, Marc Vervloet, Marta Ruiz-Ortega, Olivier Devuyst, Patrick
Pubblicato in: Kidney International Reports, Numero 2023 Apr; 8(4): 912–915., 2023, ISSN 2468-0249
Editore: Elsevier Inc.
DOI: 10.1016/j.ekir.2023.01.003

Association between Long-Term Change in Arterial Stiffness and Cardiovascular Outcomes in Kidney Transplant Recipients: Insights from the TRANSARTE Study

Autori: Madonna Salib 1, Arnaud Simon 2, Nicolas Girerd 1, Anna Kearney-Schwartz 3 4, Patrick Rossignol 1, Athanase Benetos 3 4, Luc Frimat 2, Sophie Girerd 1 2
Pubblicato in: Journal of Clinical Medicine, Numero 2022, 11(5), 1410, 2022, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11051410

IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis

Autori: Vanessa Marchant, Antonio Tejera-Muñoz, Laura Marquez-Expósito, Sandra Rayego-Mateos, Raul R. Rodrigues-Diez, Lucia Tejedor, Laura Santos-Sanchez, Jesús Egido, Alberto Ortiz, Jose M. Valdivielso, Donald J. Fraser, Manuel López-Cabrera, Rafael Selgas, Marta Ruiz-Ortega
Pubblicato in: Biomolecules, Numero 10/10, 2020, Pagina/e 1361, ISSN 2218-273X
Editore: Biomolecules
DOI: 10.3390/biom10101361

Oxidative Stress and Cellular Senescence Are Involved in the Aging Kidney

Autori: Lucia Tejedor-Santamaria 1 2, Jose Luis Morgado-Pascual 1 2, Laura Marquez-Exposito 1 2, Beatriz Suarez-Alvarez 2 3, Raul R Rodrigues-Diez 2 3, Antonio Tejera-Muñoz 1 2, Vanessa Marchant 1 2, Sergio Mezzano 4, Carlos Lopez-Larrea 2 3, Anna Sola 2 5, Gema Maria Fernandez-Juarez 2 6, Alberto Ortiz 2 7, Sandra Rayego-Mateos 1 2, Marta Ruiz-Ortega 1 2
Pubblicato in: Pharmaceuticals, Numero 2022 Jan 20;15(2):121, 2022, ISSN 1424-8247
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/antiox11020301

Fasting influences aquaporin expression, water transport and adipocyte metabolism in the peritoneal membrane

Autori: Ines P D Costa; Nicolas Hautem; Gugliemo Schiano; Shinichi Uchida; Tomoya Nishino; Olivier Devuyst
Pubblicato in: Nephrology Dialysis Transplantation, 2022, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfac318

Targeting inflammation to treat diabetic kidney disease: the road to 2030.

Autori: Sandra Rayego-Mateos 1, Raul R Rodrigues-Diez 2, Beatriz Fernandez-Fernandez 3, Carmen Mora-Fernández 4, Vanessa Marchant 1, Javier Donate-Correa 4, Juan F Navarro-González 5, Alberto Ortiz 3, Marta Ruiz-Ortega 6
Pubblicato in: Kidney International, Numero Volume 103, Numero 2, February 2023, 2023, Pagina/e Pages 282 - 296, ISSN 0085-2538
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2022.10.030

SGLT2 Inhibition by Intraperitoneal Dapagliflozin Mitigates Peritoneal Fibrosis and Ultrafiltration Failure in a Mouse Model of Chronic Peritoneal Exposure to High-Glucose Dialysate

Autori: Michael S. Balzer, Song Rong, Johannes Nordlohne, Jan D. Zemtsovski, Sonja Schmidt, Britta Stapel, Maria Bartosova, Sibylle von Vietinghoff, Hermann Haller, Claus P. Schmitt, Nelli Shushakova
Pubblicato in: Biomolecules, Numero 10/11, 2020, Pagina/e 1573, ISSN 2218-273X
Editore: MDPI
DOI: 10.3390/biom10111573

Statins: Could an old friend help in the fight against COVID-19?

Autori: Raúl R. Rodrigues-Diez; Antonio Tejera-Muñoz; Laura Marquez-Exposito; Sandra Rayego-Mateos; Sandra Rayego-Mateos; Laura Sanchez; Vanessa Marchant; Lucía Tejedor Santamaria; Adrian M. Ramos; Adrian M. Ramos; Alberto Ortiz; Alberto Ortiz; Jesús Egido; Marta Ruiz-Ortega
Pubblicato in: British Journal of Pharmacology, Numero Volume 177, Numero 21, 2020, Pagina/e Pages 4873 - 4886, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.15166

Expression of paracellular junction components and transcellular transporters in health, CKD5 and peritoneal dialysis

Autori: Iva Marinovic, Maria Bartosova, Eszter Lévai, David Ridinger, Betti Schaefer, Conghui Zhang, Rebecca Herzog, Peter Sallay, Karel Vondrak, Felix Bestvater, Michael Hausmann, Klaus Kratochwill, Sotirios G Zarogiannis, Claus Schmitt
Pubblicato in: Nephrology Dialysis Transplantation, 2021
Editore: Oxford University Press on behalf of ERA-EDTA
DOI: 10.1093/ndt/gfab101.005

Molecular and Functional Characterization of the Mesothelial and Endothelial Cell Barrier in Health, Ckd and Peritoneal Dialysis

Autori: Iva Marinovic, Maria Bartosova, Rebecca Herzog, Juan Manuel Sacnun, Conghui Zhang, Eszter Levai, Robin Hoogenboom, Karel Vondrak, Peter Sallay, Jun Oh, Sotirios G Zarogiannis, Klaus Kratochwill, Claus Peter Schmitt
Pubblicato in: Nephrology Dialysis Transplantation, 2022
Editore: Oxford University Press
DOI: 10.1093/ndt/gfac117.001

Tight Junction’s Regulation in Health, CKD5 and Peritoneal Dialysis With Low and High GDP Fluids

Autori: Iva Marinovic (1), Maria Bartosova (1), Rebecca Herzog (2), Eszter Levai (1), David Ridinger (3), Betti Schaefer (1), Conghui Zhang (1), Bradley Warady (4), Peter Sallay (5), Michael Hausmann (3), Klaus Kratochwill (6), Sotirios G Zarogiannis (7), Claus P Schmitt (1)
Pubblicato in: Abstracts of the Annual Dialysis Conference - 5th- 7th March 2021, Virtual Conference, 2021, ISSN 0896-8608
Editore: Peritoneal dialysis international
DOI: 10.1177/0896860820987674

The absence of STING prevents peritoneal damage in a murine model of peritoneal fibrosis.

Autori: Vanessa Marchant1,2, Jorge García-Giménez2,3, Guadalupe González4, Irene Rubio-Soto1,2, Valeria Kopytina4, Antonio Tejera1,2, Lucia Tejedor1,2, Laura Marquez-Exposito1,2, Manuel López-Cabrera4, Adrián Mario Ramos Cortassa2,3 and Marta Ruiz-Ortega1
Pubblicato in: Nephrology Dialysis Transplantation, 2022
Editore: Oxford University Press
DOI: 10.1093/ndt/gfac117.002

Kidney Transplantation Partially Reverses Peritoneal Dialysis Induced Pathomechanisms of Pathomechanisms of Peritoneal Membrane Transformation.

Autori: Conghui Zhang (1), Maria Bartosova (2), Rebecca Herzog (3), Betti Schaefer (1), Iva Marinovic (1), Ivan Damgov (4), Rimante Cerkauskiene (5), Sotirios G Zarogiannis (6), Klaus Kratochwill (7), Claus Peter Schmitt (1)
Pubblicato in: Abstracts of the Annual Dialysis Conference - 5th- 7th March 2021, Virtual Conference, 2021
Editore: Peritoneal Dialysis International

Increased kidney carnosine and anserine concentrations reduce renal oxidative stress and transiently improve survival in diabetic mice

Autori: Tilman Pfeffer, Philip Kirschner, Charlotte Wetzel, Maria Bartosova, Tanja Poth, Gernot Poschet, Johanna Zemva, Ivan Damgov, Sven Garbade, Kristina Klingbeil, Claus Peter Schmitt, Verena Peters
Pubblicato in: Diabetologie und Stoffwechsel, 2022
Editore: Thieme Publishing Group
DOI: 10.1055/s-0042-1746362

Molecular Mechanisms of Vascular Ageing in Children With Chronic Kidney Disease

Autori: Maria Bartosova, Conghui Zhang, Rebecca Herzog, Julie Bernardor, Charlotte Wetzel, Iva Marinovic, Zhiwei Du, Ivan Damgov, Betti Schaefer, Anette Melk, Guenter Klaus, Rimante Cerkauskiene, Klaus Arbeiter, Verena Peters, Klaus Kratochwill, Claus Peter Schmitt
Pubblicato in: Nephrology Dialysis Transplantation, 2022, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfac070.079

MO669: Predictive Parameters of Automated PD Cycler Software for Diagnosis of Catheter Dysfunction Challenges to Dialysis Treatment during the COVID-19 Pandemic: A Qualitative Study of Patients’ and Experts’ Perspectives

Autori: Krystell Arianna Oviedo Flores, Lukas Kaltenegger, Fabian Eibensteiner, Markus Unterwurzacher, Klaus Kratochwill, Christoph Aufricht, Franz König, Andreas Vychytil
Pubblicato in: Nephrology Dialysis Transplantation, Numero Volume 37, Numero Supplement_3, May 2022, gfac078.006,, 2022, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfac078.006

Evaluation of an in vitro co-culture model for testing effects of cytoprotective additives in PD fluids on cardiovascular outcome

Autori: Juan Manuel Sacnun, Rebecca Herzog, Maria Bartosova, Claus Schmitt, Klaus Kratochwill
Pubblicato in: 2020
Editore: Oxford University Press

Prognostic models to predict cardiovascular events, cardiovascular mortality and all-cause mortality: a systematic review and meta-analyses

Autori: OBAIDA ISTANBULY, Simon Davies. Prognostic models to predict cardiovascular events, cardiovascular mortality and all-cause mortality: a systematic review and meta-analyses.
Pubblicato in: PROSPERO, Numero CRD42021257959, 2021
Editore: PROSPERO

Interleukin-6 as a Prognostic Biomarker for Mortality in the Dialysis Population: a SystematicReview and Meta-Analyses

Autori: OBAIDA ISTANBULY, Simon Davies, Mark Lambie, John Belcher, Ivonne Solis-Trapala
Pubblicato in: PROSPERO, Numero CRD42020214198, 2020
Editore: PROSPERO

Redox profiling in mesothelial cells in experimental peritoneal dialysis

Autori: Rebecca Herzog, Anja Wagner, Klaus Kratochwill
Pubblicato in: 2020
Editore: Oxford University Press

Declining peritoneal host defences revealed by ex-vivo cytokine release assay of peritoneal dialysis effluent cells

Autori: Rebecca Herzog, Andreas Vychytil, Christoph Aufricht, Klaus Kratochwill
Pubblicato in: 57th ERA-EDTA Congress Abstracts, 2020
Editore: Oxford University Press

È in corso la ricerca di dati su OpenAIRE...

Identification and Management of Patients at Risk – Outcome and Vascular Events in Peritoneal Dialysis

Risultati finali

Pubblicazioni

Condividi questa pagina

Scarica