Training innovative future leaders in research and development of materials and implants for the spine

Información del proyecto

NU-SPINE

Identificador del acuerdo de subvención: 812765

DOI

10.3030/812765

Proyecto cerrado

Fecha de la firma de la CE 13 Septiembre 2018

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Septiembre 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 272 380,36

Aportación de la UE

€ 4 272 380,36

Coordinado por

UPPSALA UNIVERSITET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (12)

Assessment of the facet joint prosthesis incl. tribological testing

Assessment of the facet joint prosthesis incl tribological testing

Yearly publication lists
Testing standard for dynamic characterisation of Si3N4 implants
New testing protocols developed
Report on in vivo trials
Validation of ParFE optimization algorithm
Tribocorrosion and degradation mechanisms of coated implants
Method for wear particle isolation and full characterisation of wear products
Advanced 3D in vitro models for neurotoxicity assessment
Testing protocols deployed and validated
Neurotoxicity of wear products of SixNy
Yearly newsletters

Other (4)

Delivery of ESR courses 5 and 7
Report on network-wide ESR courses 1-4
Online introductory course to IPR 1
Report on network-wide ESR courses 5-7

Websites, patent fillings, videos etc. (2)

Public Engagement Seminar series delivered by ESRs
Website and online repository

Publicaciones

Peer reviewed articles (29)

Comprehensive in vitro comparison of cellular and osteogenic response to alternative biomaterials for spinal implants

Autores: Seung-Hun Lee; Stephanie Huber; Stephen J. Ferguson
Publicado en: Biomaterials Advances, 127, Edición 17, 2021, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.bas.2021.100006

In Vitro Biomechanics of the Cervical Spine: A Systematic Review.

Autores: Hossein Ansaripour; Stephen J. Ferguson; Markus Flohr
Publicado en: Journal of Biomechanical Engineering, 144 (10), Edición 11, 2022, ISSN 0148-0731
Editor: ASME
DOI: 10.1115/1.4054439

An ex-vivo model for the biomechanical assessment of cement discoplasty

Autores: Ghandour S, Pazarlis K, Lewin S, Isaksson P, Försth P, Persson C.
Publicado en: Front Bioeng Biotechnol, 2022, ISSN 2296-4185
Editor: PubMed
DOI: 10.3389/fbioe.2022.939717

Non-linear mechanical properties and dynamic response of silicon nitride bioceramic

Autores: Xiaoyu Du, Gurdial Blugan, Tina Künniger, Seunghun S. Lee, Liliya Vladislavova, Stephen J. Ferguson
Publicado en: Ceramics International, Edición 47/23, 2021, Página(s) 33525-33536, ISSN 0272-8842
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.ceramint.2021.08.261

3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants

Autores: Xiaoyu Du; Sean Ronayne; Seunghun S. Lee; Jackson Hendry; Douglas Hoxworth; Ryan Bock; Stephen J. Ferguson
Publicado en: ACS Applied Bio Materials, 6 (8), Edición 11, 2023, ISSN 2576-6422
Editor: ACS Appl. Bio Mater.
DOI: 10.1021/acsabm.3c00383

Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial properties

Autores: Huasi Zhou, Cecilia Persson, Olivier Donzel-Gargand, Håkan Engqvist, Wei Xia
Publicado en: Journal of the European Ceramic Society, Edición 44, 2024, Página(s) 4260-4271, ISSN 0955-2219
Editor: Elsevier BV
DOI: 10.1016/j.jeurceramsoc.2024.01.016

Bioactive silicon nitride implants through surface modification

Autores: Ioannis Katsaros; Ken Welch; Wei Xia; Cecilia Persson; Håkan Engqvist
Publicado en: Brain and Spine, Vol 1, Iss , Pp 100124- (2021), Edición 13, 2021, ISSN 2772-5294
Editor: Elsevier
DOI: 10.1016/j.bas.2021.100124

Conceptual design of compliant bone scaffolds by full-scale topology optimization

Autores: Thijs Smit; Stijn Koppen; Stephen J. Ferguson; Benedikt Helgason
Publicado en: urn:issn:1751-6161, Edición 20, 2023, ISSN 1751-6161
Editor: Elsevier BV
DOI: 10.1016/j.jmbbm.2023.105886

Scaffolds for bone-tissue engineering

Autores: Seunghun S. Lee; Xiaoyu Du; Inseon Kim; Stephen J. Ferguson
Publicado en: Matter, 5 (9), Edición 1, 2022, ISSN 2590-2385
Editor: ScienceDirect
DOI: 10.1016/j.matt.2022.06.003

Current status and future potential of wear-resistant coatings and articulating surfaces for hip and knee implants

Autores: Charlotte Skjöldebrand; Joanne L. Tipper; Peter Hatto; Michael Bryant; Richard M. Hall; Cecilia Persson
Publicado en: Crossref, Edición 4, 2022, ISSN 2590-0064
Editor: PubMed
DOI: 10.1016/j.mtbio.2022.100270

Correlation between mechanical properties and porosity in silicon nitride bioceramic

Autores: Xiaoyu Du; Gurdial Blugan; Stephen J. Ferguson
Publicado en: Brain and Spine, Vol 1, Iss , Pp 100075- (2021), Edición 23, 2021, ISSN 2772-5294
Editor: ELSEVIER
DOI: 10.1016/j.bas.2021.100075

Silicon Nitride as a Biomedical Material: An Overview

Autores: Du, Xiaoyu; id_orcid0000-0003-2532-731X; Lee, Seunghun S.; Blugan, Gurdial; Ferguson, Stephen J.; id_orcid0000-0003-0650-5889
Publicado en: International Journal of Molecular Sciences, 23 (12), Edición 22, 2022, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126551

Topology optimization using PETSc: a Python wrapper and extended functionality

Autores: Thijs Smit; Niels Aage; Stephen J. Ferguson; Benedikt Helgason
Publicado en: Structural and Multidisciplinary Optimization, 64 (4), Edición 14, 2021, ISSN 1615-1488
Editor: SpringerLink
DOI: 10.1007/s00158-021-03018-7

Silicon Nitride, a Bioceramic for Bone Tissue Engineering: A Reinforced Cryogel System With Antibiofilm and Osteogenic Effects

Autores: Seunghun S. Lee; Leanid Laganenka; Xiaoyu Du; Wolf-Dietrich Hardt; Stephen J. Ferguson
Publicado en: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021), Edición 3, 2021, ISSN 2296-4185
Editor: Frontiers
DOI: 10.3389/fbioe.2021.794586

Bioactive Silicon Nitride Implant Surfaces with Maintained Antibacterial Properties

Autores: Ioannis Katsaros; Yijun Zhou; Ken Welch; Wei Xia; Cecilia Persson; Håkan Engqvist
Publicado en: Journal of Functional Biomaterials; Volume 13; Edición 3; Pages: 129, Edición 10, 2022, ISSN 2079-4983
Editor: National Library of Medicine
DOI: 10.3390/jfb13030129

The porous cantilever beam as a model for spinal implants: Experimental, analytical and finite element analysis of dynamic properties

Autores: Xiaoyu Du; Yijun Zhou; Lingzhen Li; Cecilia Persson; Stephen J. Ferguson
Publicado en: Mathematical Biosciences and Engineering, 20 (4), Edición 7, 2023, ISSN 1551-0018
Editor: AIMS Press
DOI: 10.3934/mbe.2023270

Hydroxyapatite particle shape affects screw attachment in cancellous bone when augmented with hydroxyapatite-containing hydrogels

Autores: Yijun Zhou; Lisa Höglund; Ayan Samanta; Philip Procter; Cecilia Persson
Publicado en: Journal of the Mechanical Behavior of Biomedical Materials, 2024, ISSN 1751-6161
Editor: Elsevier BV
DOI: 10.1016/j.jmbbm.2023.106241

SiNx Coating Deposition on CoCr by Plasma-Enhanced Chemical Vapor Deposition

Autores: Huasi Zhou, Cecilia Persson, Wei Xia, Håkan Engqvist
Publicado en: Biomedical Materials & Devices, Edición 2, 2024, Página(s) 376-383, ISSN 2731-4812
Editor: Springer Science and Business Media LLC
DOI: 10.1007/s44174-023-00083-y

A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration

Autores: Seung-Hun Lee; Matthias Santschi; Stephen J. Ferguson
Publicado en: Biomacromolecules, 22 (6), Edición 5, 2022, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000493840

Ceramics in total disc replacements: A scoping review

Autores: Lucia Kölle; Dominika Ignasiak; Stephen J. Ferguson; Benedikt Helgason
Publicado en: Clinical Biomechanics, 100, Edición 5, 2022, ISSN 0268-0033
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.clinbiomech.2022.105796

Comprehensive in vitro comparison of cellular and osteogenic response to alternative biomaterials for spinal implants

Autores: Seunghun S. Lee, Stephanie Huber, Stephen J. Ferguson
Publicado en: Materials Science and Engineering: C, Edición 127, 2021, Página(s) 112251, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.msec.2021.112251

Correction to “A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration”

Autores: Seunghun S. Lee; Matthias Santschi; Stephen J. Ferguson
Publicado en: Crossref, Edición 4, 2023, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.2c00203

A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration

Autores: Seunghun S. Lee, Matthias Santschi, Stephen J. Ferguson
Publicado en: Biomacromolecules, 2021, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.1c00241

A 3D-Printed Assemblable Bespoke Scaffold as a Versatile Microcryogel Carrier for Site-Specific Regenerative Medicine

Autores: Lee, Seunghun S.; Kleger, Nicole; Kuhn, Gisela A.; Greutert, Helen; Du, Xiaoyu; Smit, Thijs; Studart, André R.; Ferguson, Stephen J.
Publicado en: Advanced Materials, Edición 7, 2023, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.3929/ethz-b-000634325

Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels

Autores: Estefanía Echeverri; Charlotte Skjöldebrand; Paul O'Callaghan; Anders Palmquist; Johan Kreuger; Gry Hulsart-Billström; Cecilia Persson
Publicado en: Crossref, Edición 5, 2023, ISSN 2047-4830
Editor: Royal Society of Chemistry
DOI: 10.1039/d2bm02074b

A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

Autores: Inseon Kim; Seunghun S. Lee; Adhideb Ghosh; Stephen J. Ferguson; Ori Bar‐Nur
Publicado en: Advanced Functional Materials, Edición 11, 2024, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1101/2023.04.10.534929

Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium

Autores: Charlotte Skjöldebrand; Estefanía Echeverri; Gry Hulsart-Billström; Cecilia Persson
Publicado en: Crossref, Edición 4, 2022, ISSN 2047-4830
Editor: Royal Society of Chemistry
DOI: 10.1039/d1bm01978c

3D-printed LEGO®-inspired titanium scaffolds for patient-specific regenerative medicine

Autores: Seunghun S. Lee; Xiaoyu Du; Thijs Smit; Elisa G. Bissacco; Daniel Seiler; Michael de Wild; Stephen J. Ferguson
Publicado en: Crossref, Edición 4, 2023, ISSN 2772-9508
Editor: ScienceDirect
DOI: 10.1016/j.bioadv.2023.213617

Quasi-static and dynamic mechanical properties of a linoleic acid-modified, low-modulus bone cement for spinal applications

Autores: Salim Ghandour, Iain Christie, Caroline Öhman Mägi, Cecilia Persson
Publicado en: Open Research Europe, Edición 3, 2024, Página(s) 203, ISSN 2732-5121
Editor: F1000 Research Ltd
DOI: 10.12688/openreseurope.16683.2

Thesis and dissertations (1)

Osseointegration of Biomaterials for Orthopaedic Implants

Autores: Lee, Seung Hun
Publicado en: 2023
Editor: ETH Zurich
DOI: 10.3929/ethz-b-000600496

Other (2)

Explicit FE simulation results for orthopedic screw-bone interaction, for different screw geometries and bone quality

Autores: Zhou, Yijun Helgason, Benedikt Ferguson, Stephen Persson, Cecilia
Publicado en: 2023
Editor: Zenodo
DOI: 10.5281/zenodo.8388808

Quasi-static and dynamic mechanical properties of a low-modulus bone cement for spinal applications

Autores: Salim Ghandour; Iain Christie; Caroline Öhman Mägi; Cecilia Persson
Publicado en: 2023
Editor: Open Research Europe
DOI: 10.12688/openreseurope.16683.1