Training innovative future leaders in research and development of materials and implants for the spine

Informacje na temat projektu

NU-SPINE

Identyfikator umowy o grant: 812765

DOI

10.3030/812765

Projekt został zamknięty

Data podpisania przez KE 13 Września 2018

Data rozpoczęcia 1 Stycznia 2019

Data zakończenia 30 Września 2023

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 4 272 380,36

Wkład UE

€ 4 272 380,36

Koordynowany przez

UPPSALA UNIVERSITET
Sweden

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (12)

Assessment of the facet joint prosthesis incl. tribological testing

Assessment of the facet joint prosthesis incl tribological testing

Yearly publication lists
Testing standard for dynamic characterisation of Si3N4 implants
New testing protocols developed
Report on in vivo trials
Validation of ParFE optimization algorithm
Tribocorrosion and degradation mechanisms of coated implants
Method for wear particle isolation and full characterisation of wear products
Advanced 3D in vitro models for neurotoxicity assessment
Testing protocols deployed and validated
Neurotoxicity of wear products of SixNy
Yearly newsletters

Other (4)

Delivery of ESR courses 5 and 7
Report on network-wide ESR courses 1-4
Online introductory course to IPR 1
Report on network-wide ESR courses 5-7

Websites, patent fillings, videos etc. (2)

Public Engagement Seminar series delivered by ESRs
Website and online repository

Publikacje

Peer reviewed articles (29)

Comprehensive in vitro comparison of cellular and osteogenic response to alternative biomaterials for spinal implants

Autorzy: Seung-Hun Lee; Stephanie Huber; Stephen J. Ferguson
Opublikowane w: Biomaterials Advances, 127, Numer 17, 2021, ISSN 0928-4931
Wydawca: Elsevier BV
DOI: 10.1016/j.bas.2021.100006

In Vitro Biomechanics of the Cervical Spine: A Systematic Review.

Autorzy: Hossein Ansaripour; Stephen J. Ferguson; Markus Flohr
Opublikowane w: Journal of Biomechanical Engineering, 144 (10), Numer 11, 2022, ISSN 0148-0731
Wydawca: ASME
DOI: 10.1115/1.4054439

An ex-vivo model for the biomechanical assessment of cement discoplasty

Autorzy: Ghandour S, Pazarlis K, Lewin S, Isaksson P, Försth P, Persson C.
Opublikowane w: Front Bioeng Biotechnol, 2022, ISSN 2296-4185
Wydawca: PubMed
DOI: 10.3389/fbioe.2022.939717

Non-linear mechanical properties and dynamic response of silicon nitride bioceramic

Autorzy: Xiaoyu Du, Gurdial Blugan, Tina Künniger, Seunghun S. Lee, Liliya Vladislavova, Stephen J. Ferguson
Opublikowane w: Ceramics International, Numer 47/23, 2021, Strona(/y) 33525-33536, ISSN 0272-8842
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.ceramint.2021.08.261

3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants

Autorzy: Xiaoyu Du; Sean Ronayne; Seunghun S. Lee; Jackson Hendry; Douglas Hoxworth; Ryan Bock; Stephen J. Ferguson
Opublikowane w: ACS Applied Bio Materials, 6 (8), Numer 11, 2023, ISSN 2576-6422
Wydawca: ACS Appl. Bio Mater.
DOI: 10.1021/acsabm.3c00383

Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial properties

Autorzy: Huasi Zhou, Cecilia Persson, Olivier Donzel-Gargand, Håkan Engqvist, Wei Xia
Opublikowane w: Journal of the European Ceramic Society, Numer 44, 2024, Strona(/y) 4260-4271, ISSN 0955-2219
Wydawca: Elsevier BV
DOI: 10.1016/j.jeurceramsoc.2024.01.016

Bioactive silicon nitride implants through surface modification

Autorzy: Ioannis Katsaros; Ken Welch; Wei Xia; Cecilia Persson; Håkan Engqvist
Opublikowane w: Brain and Spine, Vol 1, Iss , Pp 100124- (2021), Numer 13, 2021, ISSN 2772-5294
Wydawca: Elsevier
DOI: 10.1016/j.bas.2021.100124

Conceptual design of compliant bone scaffolds by full-scale topology optimization

Autorzy: Thijs Smit; Stijn Koppen; Stephen J. Ferguson; Benedikt Helgason
Opublikowane w: urn:issn:1751-6161, Numer 20, 2023, ISSN 1751-6161
Wydawca: Elsevier BV
DOI: 10.1016/j.jmbbm.2023.105886

Scaffolds for bone-tissue engineering

Autorzy: Seunghun S. Lee; Xiaoyu Du; Inseon Kim; Stephen J. Ferguson
Opublikowane w: Matter, 5 (9), Numer 1, 2022, ISSN 2590-2385
Wydawca: ScienceDirect
DOI: 10.1016/j.matt.2022.06.003

Current status and future potential of wear-resistant coatings and articulating surfaces for hip and knee implants

Autorzy: Charlotte Skjöldebrand; Joanne L. Tipper; Peter Hatto; Michael Bryant; Richard M. Hall; Cecilia Persson
Opublikowane w: Crossref, Numer 4, 2022, ISSN 2590-0064
Wydawca: PubMed
DOI: 10.1016/j.mtbio.2022.100270

Correlation between mechanical properties and porosity in silicon nitride bioceramic

Autorzy: Xiaoyu Du; Gurdial Blugan; Stephen J. Ferguson
Opublikowane w: Brain and Spine, Vol 1, Iss , Pp 100075- (2021), Numer 23, 2021, ISSN 2772-5294
Wydawca: ELSEVIER
DOI: 10.1016/j.bas.2021.100075

Silicon Nitride as a Biomedical Material: An Overview

Autorzy: Du, Xiaoyu; id_orcid0000-0003-2532-731X; Lee, Seunghun S.; Blugan, Gurdial; Ferguson, Stephen J.; id_orcid0000-0003-0650-5889
Opublikowane w: International Journal of Molecular Sciences, 23 (12), Numer 22, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126551

Topology optimization using PETSc: a Python wrapper and extended functionality

Autorzy: Thijs Smit; Niels Aage; Stephen J. Ferguson; Benedikt Helgason
Opublikowane w: Structural and Multidisciplinary Optimization, 64 (4), Numer 14, 2021, ISSN 1615-1488
Wydawca: SpringerLink
DOI: 10.1007/s00158-021-03018-7

Silicon Nitride, a Bioceramic for Bone Tissue Engineering: A Reinforced Cryogel System With Antibiofilm and Osteogenic Effects

Autorzy: Seunghun S. Lee; Leanid Laganenka; Xiaoyu Du; Wolf-Dietrich Hardt; Stephen J. Ferguson
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021), Numer 3, 2021, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2021.794586

Bioactive Silicon Nitride Implant Surfaces with Maintained Antibacterial Properties

Autorzy: Ioannis Katsaros; Yijun Zhou; Ken Welch; Wei Xia; Cecilia Persson; Håkan Engqvist
Opublikowane w: Journal of Functional Biomaterials; Volume 13; Numer 3; Pages: 129, Numer 10, 2022, ISSN 2079-4983
Wydawca: National Library of Medicine
DOI: 10.3390/jfb13030129

The porous cantilever beam as a model for spinal implants: Experimental, analytical and finite element analysis of dynamic properties

Autorzy: Xiaoyu Du; Yijun Zhou; Lingzhen Li; Cecilia Persson; Stephen J. Ferguson
Opublikowane w: Mathematical Biosciences and Engineering, 20 (4), Numer 7, 2023, ISSN 1551-0018
Wydawca: AIMS Press
DOI: 10.3934/mbe.2023270

Hydroxyapatite particle shape affects screw attachment in cancellous bone when augmented with hydroxyapatite-containing hydrogels

Autorzy: Yijun Zhou; Lisa Höglund; Ayan Samanta; Philip Procter; Cecilia Persson
Opublikowane w: Journal of the Mechanical Behavior of Biomedical Materials, 2024, ISSN 1751-6161
Wydawca: Elsevier BV
DOI: 10.1016/j.jmbbm.2023.106241

SiNx Coating Deposition on CoCr by Plasma-Enhanced Chemical Vapor Deposition

Autorzy: Huasi Zhou, Cecilia Persson, Wei Xia, Håkan Engqvist
Opublikowane w: Biomedical Materials & Devices, Numer 2, 2024, Strona(/y) 376-383, ISSN 2731-4812
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/s44174-023-00083-y

A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration

Autorzy: Seung-Hun Lee; Matthias Santschi; Stephen J. Ferguson
Opublikowane w: Biomacromolecules, 22 (6), Numer 5, 2022, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.3929/ethz-b-000493840

Ceramics in total disc replacements: A scoping review

Autorzy: Lucia Kölle; Dominika Ignasiak; Stephen J. Ferguson; Benedikt Helgason
Opublikowane w: Clinical Biomechanics, 100, Numer 5, 2022, ISSN 0268-0033
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.clinbiomech.2022.105796

Comprehensive in vitro comparison of cellular and osteogenic response to alternative biomaterials for spinal implants

Autorzy: Seunghun S. Lee, Stephanie Huber, Stephen J. Ferguson
Opublikowane w: Materials Science and Engineering: C, Numer 127, 2021, Strona(/y) 112251, ISSN 0928-4931
Wydawca: Elsevier BV
DOI: 10.1016/j.msec.2021.112251

Correction to “A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration”

Autorzy: Seunghun S. Lee; Matthias Santschi; Stephen J. Ferguson
Opublikowane w: Crossref, Numer 4, 2023, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c00203

A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration

Autorzy: Seunghun S. Lee, Matthias Santschi, Stephen J. Ferguson
Opublikowane w: Biomacromolecules, 2021, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.1c00241

A 3D-Printed Assemblable Bespoke Scaffold as a Versatile Microcryogel Carrier for Site-Specific Regenerative Medicine

Autorzy: Lee, Seunghun S.; Kleger, Nicole; Kuhn, Gisela A.; Greutert, Helen; Du, Xiaoyu; Smit, Thijs; Studart, André R.; Ferguson, Stephen J.
Opublikowane w: Advanced Materials, Numer 7, 2023, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.3929/ethz-b-000634325

Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels

Autorzy: Estefanía Echeverri; Charlotte Skjöldebrand; Paul O'Callaghan; Anders Palmquist; Johan Kreuger; Gry Hulsart-Billström; Cecilia Persson
Opublikowane w: Crossref, Numer 5, 2023, ISSN 2047-4830
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2bm02074b

A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

Autorzy: Inseon Kim; Seunghun S. Lee; Adhideb Ghosh; Stephen J. Ferguson; Ori Bar‐Nur
Opublikowane w: Advanced Functional Materials, Numer 11, 2024, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1101/2023.04.10.534929

Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium

Autorzy: Charlotte Skjöldebrand; Estefanía Echeverri; Gry Hulsart-Billström; Cecilia Persson
Opublikowane w: Crossref, Numer 4, 2022, ISSN 2047-4830
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1bm01978c

3D-printed LEGO®-inspired titanium scaffolds for patient-specific regenerative medicine

Autorzy: Seunghun S. Lee; Xiaoyu Du; Thijs Smit; Elisa G. Bissacco; Daniel Seiler; Michael de Wild; Stephen J. Ferguson
Opublikowane w: Crossref, Numer 4, 2023, ISSN 2772-9508
Wydawca: ScienceDirect
DOI: 10.1016/j.bioadv.2023.213617

Quasi-static and dynamic mechanical properties of a linoleic acid-modified, low-modulus bone cement for spinal applications

Autorzy: Salim Ghandour, Iain Christie, Caroline Öhman Mägi, Cecilia Persson
Opublikowane w: Open Research Europe, Numer 3, 2024, Strona(/y) 203, ISSN 2732-5121
Wydawca: F1000 Research Ltd
DOI: 10.12688/openreseurope.16683.2

Thesis and dissertations (1)

Osseointegration of Biomaterials for Orthopaedic Implants

Autorzy: Lee, Seung Hun
Opublikowane w: 2023
Wydawca: ETH Zurich
DOI: 10.3929/ethz-b-000600496

Other (2)

Explicit FE simulation results for orthopedic screw-bone interaction, for different screw geometries and bone quality

Autorzy: Zhou, Yijun Helgason, Benedikt Ferguson, Stephen Persson, Cecilia
Opublikowane w: 2023
Wydawca: Zenodo
DOI: 10.5281/zenodo.8388808

Quasi-static and dynamic mechanical properties of a low-modulus bone cement for spinal applications

Autorzy: Salim Ghandour; Iain Christie; Caroline Öhman Mägi; Cecilia Persson
Opublikowane w: 2023
Wydawca: Open Research Europe
DOI: 10.12688/openreseurope.16683.1