Breaking Bad Biofilms. Innovative Analysis and Design Rules for Next-Generation Antifouling Interfaces

Informazioni relative al progetto

BREAK BIOFILMS

ID dell’accordo di sovvenzione: 813439

DOI 10.3030/813439

Progetto chiuso

Data della firma CE 20 Agosto 2018

Data di avvio 1 Gennaio 2019

Data di completamento 30 Aprile 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale € 4 033 858,32

Contributo UE € 4 033 858,32

Coordinato da

UNIVERSIDAD DE OVIEDO
Spain

Risultati finali

Documents, reports (12)

Highly efficient nano/micro-textured surfaces for efficient pathogen capture >80% at 100 CFU/ml.

Highly efficient nanomicrotextured surfaces for efficient pathogen capture 80 at 100 CFUml

Post-project exploitation plan

Postproject exploitation plan

Generic scheme for Virtual Company concept transferable to other ITN projects
"Business Plan of the ESR ""virtual company"""

Business Plan of the ESR virtual company

3rd annual report
1st annual report
Report on Gender balance and gender case studies
2nd annual report
"Report on ""in vitro"" toxicity of the anti-biofilm novel formulations"

Report on in vitro toxicity of the antibiofilm novel formulations

Proceedings volume of final Breaking Biofilms Conference
Understanding of chemical processes within biofilms
Disposable paper microfluidic platforms for the study of biofilm activity and biocide high throughput screening

Websites, patent fillings, videos etc. (1)

Project website established

Other (1)

Establishment of social media presence

Pubblicazioni

Peer reviewed articles (38)

Draft genome sequences of the bap-producing strain staphylococcus aureus v329 and its derived phage-resistant mutant bim-1

Autori: Lucía Fernández, Ana Catarina Duarte, Beatriz Martínez, Ana Rodríguez, Pilar García
Pubblicato in: Microbiology Resource Announcements, 2021, ISSN 2576-098X
Editore: American Society for Microbiology
DOI: 10.1128/mra.00500-21

Fe3O4@Au Core–Shell Magnetic Nanoparticles for the Rapid Analysis of E. coli O157:H7 in an Electrochemical Immunoassay

Autori: Shayesteh Bazsefidpar, Maria Freitas, Clara R. Pereira, Gemma Gutiérrez, Esther Serrano-Pertierra, Henri P. A. Nouws, María Matos, Cristina Delerue-Matos and María Carmen Blanco-López
Pubblicato in: Biosensors, Numero 13, 2023, Pagina/e 567, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios13050567

Vesicles as antibiotic carrier: State of art

Autori: Verdiana Marchianò, María Matos, Esther Serrano-Pertierra, Gemma Gutiérrez, M.C. Blanco-López
Pubblicato in: International Journal of Pharmaceutics, Numero 585, 2020, Pagina/e 119478, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2020.119478

Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges

Autori: Elena E. Ferapontova
Pubblicato in: Current Opinion in Electrochemistry, Numero 19, 2020, Pagina/e 153-161, ISSN 2451-9103
Editore: Elsevier B.V.
DOI: 10.1016/j.coelec.2019.12.005

Electrochemical immuno-and aptamer-based assays for bacteria: Pros and cons over traditional detection schemes

Autori: Rimsha Binte Jamal, Stepan Shipovskov, Elena E. Ferapontova
Pubblicato in: Sensors, 2020, ISSN 1424-8220
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s20195561

Gram-Positive Pneumonia: Possibilities Offered by Phage Therapy

Autori: Lucía Fernández, María Dolores Cima-Cabal, Ana Catarina Duarte, Ana Rodríguez, María del Mar García-Suárez and Pilar García
Pubblicato in: Antibiotics, 2021, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics10081000

Stability of non-ionic surfactant vesicles loaded with Rifamycin S

Autori: Verdiana Marchianò, Maria Matos, Ismael Marcet, Maria Paz Cabal, Gemma Gutiérrez and Maria Carmen Blanco-López
Pubblicato in: Pharmaceutics, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122626

ZnO Nanostructures with Antibacterial Properties Prepared by a Green Electrochemical-Thermal Approach

Autori: Maria Chiara Sportelli, Rosaria Anna Picca, Margherita Izzi, Gerardo Palazzo, Roberto Gristina, Massimo Innocenti, Luisa Torsi, Nicola Cioffi
Pubblicato in: Nanomaterials, Numero 10/3, 2020, Pagina/e 473, ISSN 2079-4991
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano10030473

In situ monitoring of Lentilactobacillus parabuchneri biofilm formation via real-time infrared spectroscopy

Autori: Diellza Bajrami, Stephan Fischer, Holger Barth, María A. Sarquis, Victor M. Ladero, María Fernández, Maria. C. Sportelli, Nicola Cioffi, Christine Kranz and Boris Mizaikoff
Pubblicato in: npj Biofilms and Microbiomes, 2022, ISSN 2055-5008
Editore: Springer Nature
DOI: 10.1038/s41522-022-00353-5

Green Synthesis and Characterization of Antimicrobial Synergistic AgCl/BAC Nanocolloids

Autori: Syed Imdadul Hossain, Maria Chiara Sportelli, Rosaria Anna Picca, Luigi Gentile, Gerardo Palazzo, Nicoletta Ditaranto, and Nicola Cioffi
Pubblicato in: ACS Applied bio materials, 2022, ISSN 2576-6422
Editore: American Chemical Society (ACS)
DOI: 10.1021/acsabm.2c00207

Highly Stable Core-Shell Nanocolloids: Synergy between Nano-Silver and Natural Polymers to Prevent Biofilm Formation

Autori: Kukushkina, E.A.; Mateos, H.; Altun, N.; Sportelli, M.C.; Gonzalez, P.; Picca, R.A.; Cioffi, N.
Pubblicato in: Antibiotics, 2022, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics11101396

Electrochemical Preparation of Synergistic Nanoantimicrobials

Autori: Maria Chiara Sportelli, Daniela Longano, Elisabetta Bonerba, Giuseppina Tantillo, Luisa Torsi, Luigia Sabbatini, Nicola Cioffi, Nicoletta Ditaranto
Pubblicato in: Molecules, Numero 25/1, 2020, Pagina/e 49, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25010049

Lyophilised nanovesicles loaded with vitamin B12

Autori: Verdiana Marchianò, Maria Matos, Esther Serrano, José R. Álvarez, Ismael Marcet, M. Carmen Blanco-López, Gemma Gutiérrez
Pubblicato in: Journal of Molecular Liquids, 2022, ISSN 0167-7322
Editore: Elsevier BV
DOI: 10.1016/j.molliq.2022.120129

Probing and Visualizing Interfacial Charge at Surfaces in Aqueous Solution

Autori: Giada Caniglia, Gözde Tezcan, Gabriel N. Meloni, Patrick R. Unwin, Christine Kranz
Pubblicato in: Annual Review of Analytical Chemistry, 2022, ISSN 1936-1327
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-anchem-121521-122615

Atomic force and infrared spectroscopic studies on the role of surface charge for the anti-biofouling properties of polydopamine films

Autori: Giada Caniglia, Andrea Teuber, Holger Barth, Boris Mizaikoff, Christine Kranz
Pubblicato in: Analytical and Bioanalytical Chemistry, 2023, ISSN 1618-2642
Editore: Springer Verlag
DOI: 10.1007/s00216-022-04431-7

Electrochemical detection of viruses and antibodies: A mini review

Autori: Miren Ruiz de Eguilaz, Loanda R. Cumba, Robert J.Forster
Pubblicato in: Electrochemistry Communications, 2020, ISSN 1388-2481
Editore: Elsevier BV
DOI: 10.1016/j.elecom.2020.106762

Cu Nanoparticle-Loaded Nanovesicles with Antibiofilm Properties. Part I: Synthesis of New Hybrid Nanostructures

Autori: Lucia Sarcina, Pablo García-Manrique, Gemma Gutiérrez, Nicoletta Ditaranto, Nicola Cioffi, Maria Matos, Maria del Carmen Blanco-López
Pubblicato in: Nanomaterials, Numero 10/8, 2020, Pagina/e 1542, ISSN 2079-4991
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano10081542

Detection of E.coli 23S rRNA by electrocatalytic “off-on” DNA beacon assay with femtomolar sensitivity

Autori: Rimsha B. Jamal, Toni Vitasovic, Ulrich Gosewinkel, Elena E. Ferapontova
Pubblicato in: Biosensors and Bioelectronics, 2023, ISSN 0956-5663
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2023.115214

Scanning electrochemical microscopy and its potential for studying biofilms and antimicrobial coatings.

Autori: Giada Caniglia; Christine Kranz
Pubblicato in: Analytical and Bioanalytical Chemistry, Numero 1, 2020, ISSN 1618-2642
Editore: Springer Verlag
DOI: 10.1007/s00216-020-02782-7

Design and Selection of Engineered Lytic Proteins With Staphylococcus aureus Decolonizing Activity

Autori: Diana Gutiérrez, Lorena Rodríguez-Rubio, Patricia Ruas-Madiedo, Lucía Fernández, Ana Belén Campelo, Yves Briers, Martin Weiss Nielsen, Karl Pedersen, Rob Lavigne, Pilar García and Ana Rodríguez
Pubblicato in: Frontiers in Microbiology, 2021, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2021.723834

Synergistic action of phage phiIPLA-RODI and lytic protein CHAPSH3b: a combination strategy to target Staphylococcus aureus biofilms

Autori: Ana Catarina Duarte, Lucía Fernández, Vincent De Maesschalck, Diana Gutiérrez, Ana Belén Campelo, Yves Briers, Rob Lavigne, Ana Rodríguez & Pilar García
Pubblicato in: npj Biofilms and Microbiomes, 2021, ISSN 2055-5008
Editore: Nature Publishing Group
DOI: 10.1038/s41522-021-00208-5

Combined use of bacteriocins and bacteriophages as food biopreservatives. A review

Autori: Claudia Rendueles; Ana Catarina Duarte; Susana Escobedo; Lucía Fernández; Ana Rodríguez; Pilar García; Beatriz Martínez
Pubblicato in: International Journal of Food Microbiology, 2022, ISSN 0168-1605
Editore: Elsevier BV
DOI: 10.1016/j.ijfoodmicro.2022.109611

Can Nanotechnology and Materials Science Help the Fight against SARS-CoV-2?

Autori: Maria Chiara Sportelli, Margherita Izzi, Ekaterina A. Kukushkina, Syed Imdadul Hossain, Rosaria Anna Picca, Nicoletta Ditaranto, Nicola Cioffi
Pubblicato in: Nanomaterials, 2020, ISSN 2079-4991
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano10040802

Rapid and sensitive detection of E. coli O157:H7 by lateral flow immunoassay and silver enhancement

Autori: Shayesteh Bazsefidpar, Esther Serrano‑Pertierra, Gemma Gutiérrez, Alberto Sánchez Calvo, María Matos, María Carmen Blanco‑López
Pubblicato in: Microchimica Acta, 2023, ISSN 0026-3672
Editore: Springer Verlag
DOI: 10.1007/s00604-023-05834-8

Preparation of Laser-Ablated Ag Nanoparticle–MMT Clay-Based Beeswax Antibiofilm Coating

Autori: Hossain, S.I.; Bajrami, D.; Sportelli, M.C.; Picca, R.A.; Volpe, A.; Gaudiuso, C.; Ancona, A.; Gentile, L.; Palazzo, G.; Ditaranto, N.; Mizaikoff, B.; Cioffi, N
Pubblicato in: Antibiotics, 2023, ISSN 2079-6382
Editore: MDPI
DOI: 10.3390/antibiotics12020194

The relationship between the phageome and human health: Are bacteriophages beneficial or harmful microbes?

Autori: Fernández Llamas, Lucía; Duarte, Ana Catarina; Rodríguez González, Ana; García Suárez, María Pilar
Pubblicato in: Beneficial Microbes, 2021, ISSN 1876-2883
Editore: Wageningen Academic Publishers
DOI: 10.3920/bm2020.0132

Electrodecoration and Characterization of Superparamagnetic Iron Oxide Nanoparticles with Bioactive Synergistic Nanocopper: Magnetic Hyperthermia-Induced Ionic Release for Anti-Biofilm Action

Autori: Verdiana Marchianò, Maria Salvador, Amanda Moyano, Gemma Gutiérrez, María Matos, Susana Yáñez-Vilar, Yolanda Piñeiro, José Rivas, José C. Martínez-García, Davide Peddis, Maria C. Blanco-López, Montserrat Rivas, Nicoletta Ditaranto, Nicola Cioffi
Pubblicato in: Antibiotics, Numero 10/2, 2021, Pagina/e 119, ISSN 2079-6382
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/antibiotics10020119

Electrochemical ozone generation using compacted high pressure high temperature synthesized boron doped diamond microparticle electrodes

Autori: Georgia F. Wood; Irina M. Terrero Rodríguez; Joshua J. Tully; Shayantan Chaudhuri; Julie V. Macpherson
Pubblicato in: Journal of The Electrochemical Society, 2021, ISSN 0013-4651
Editore: Electrochemical Society, Inc.
DOI: 10.1149/1945-7111/ac3ff4

Sustainable antibiofilm self-assembled colloidal systems

Autori: Diana Morán, Clara Saweres-Argüelles, Verdiana Marchiano, Shayesteh Bazsefidpar, Esther Serrano-Pertierra, Maria Matos, Gemma Gutierrez and Maria Carmen Blanco-López
Pubblicato in: Frontiers in Soft Matter, Numero 2, 2022, ISSN 2813-0499
Editore: Frontiers Media
DOI: 10.3389/frsfm.2022.1041881

Nanovesicles as vanillin carriers for antimicrobial applications

Autori: Verdiana Marchianò, Maria Matos, Miriam López, Shihan Weng, Esther Serrano-Pertierra, Susana Luque, M. Carmen Blanco-López, Gemma Gutiérrez
Pubblicato in: Membranes, 2023, ISSN 2077-0375
Editore: Molecular Diversity Preservation International
DOI: 10.3390/membranes13010095

Recent advances on the spectroscopic characterization of microbial biofilms: A critical review

Autori: Sportelli, Maria Chiara; Kranz, Christine; Mizaikoff, Boris; Cioffi, Nicola
Pubblicato in: Analytica Chimica Acta, 2022, ISSN 0003-2670
Editore: Elsevier BV
DOI: 10.1016/j.aca.2022.339433

Developing Diagnostic and Therapeutic Approaches to Bacterial Infections for a New Era: Implications of Globalization

Autori: Lucía Fernández, María Dolores Cima-Cabal, Ana Catarina Duarte, Ana Rodriguez, Pilar García, María del Mar García-Suárez
Pubblicato in: Antibiotics, Numero 9/12, 2020, Pagina/e 916, ISSN 2079-6382
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/antibiotics9120916

Ag-Based Synergistic Antimicrobial Composites. A Critical Review

Autori: Ekaterina A. Kukushkina, Syed Imdadul Hossain, Maria Chiara Sportelli, Nicoletta Ditaranto, Rosaria Anna Picca, Nicola Cioffi
Pubblicato in: Nanomaterials, Numero 11/7, 2021, Pagina/e 1687, ISSN 2079-4991
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano11071687

Lipid–polymer hybrids encapsulating iron-oxide nanoparticles as a label for lateral flow immunoassays

Autori: Shayesteh Bazsefidpar, Amanda Moyano Artime, Gemma Gutiérrez Cervelló, María Matos González, María del Carmen Blanco López
Pubblicato in: Biosensors, 2021, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11070218

Characterization of the Biofilms Formed by Histamine-Producing Lentilactobacillus parabuchneri Strains in the Dairy Environment

Autori: Agustina Sarquis, Diellza Bajrami, Boris Mizaikoff, Victor Ladero, Miguel A Alvarez, Maria Fernandez
Pubblicato in: Foods, Numero 12, 2023, Pagina/e 1503, ISSN 2304-8158
Editore: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/foods12071503

Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material

Autori: Kukushkina, E.A; Tartaro, G.;.Sportelli, M.C.; Di Franco, C.; Picca, R.A.; Cioffi, N.
Pubblicato in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232415818

Silver-fluoropolymer (Ag-CFx) films: Kinetic study of silver release, and spectroscopic-microscopic insight into the inhibition of P. fluorescens biofilm formation

Autori: Giada Caniglia; Maria Chiara Sportelli; Anna Heinzmann; Rosaria A. Picca; Antonio Valentini; Holger Barth; Boris Mizaikoff; Nicola Cioffi; Christine Kranz
Pubblicato in: Analytica Chimica Acta, 2022, ISSN 0003-2670
Editore: Elsevier BV
DOI: 10.1016/j.aca.2022.339892

A Review on Montmorillonite-Based Nanoantimicrobials: State of the Art

Autori: Hossain, S.I.; Kukushkina, E.A.; Izzi, M.; Sportelli, M.C.; Picca, R.A.; Ditaranto, N.; Cioffi, N.
Pubblicato in: Nanomaterials, 2023, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/nano13050848

Book chapters (1)

Miniaturized Electrochemical Biosensors

Autori: Andreas Hellmann, Giada Caniglia, Christine Kranz
Pubblicato in: Encyclopedia of Sensors and Biosensors, 2023
Editore: Elsevier
DOI: 10.1016/b978-0-12-822548-6.00152-7