Deliverables Documents, reports (9) Delivery of supramolecular logic gates to living endothelial cells / co-cultures Based on results from D2.2, a protocol to deliver supramolecular logic gates to living endothelial cells / co-cultures is developed Animal disease models Suitable animal disease models are identified Living 2D cell cultures and co-cultures Living 2D cell cultures and co-cultures are available Proof-of-principle for TTA-UC supramolecular sensing Proof-of-principle for TTA-UC supramolecular sensing is shown Delivery of supramolecular logic gates to a MemSense or GUV membrane model A protocol for delivery of supramolecular logic gates to a MemSense or GUV membrane model is established Metabolomic profile of ED pathology A metabolomic profile of ED pathology is established Theoretical models for the excited state levels of the sensors Theoretical models for the excited state levels of the sensors are established Stable and well-characterized liposomes Stable and well-characterized liposomes are prepared to transport the logic gates in buffer and serum Photochemical and photophysical characteristics Photochemical and photophysical characteristics are known Websites, patent fillings, videos etc. (1) ESR positions are advertised ESR positions are advertised at national and European-wide portals and the LOGIC LAB website (e.g. Euraxess) Other (3) Network meeting 1 Network meeting 1 is delivered Network meeting 3 Network meeting 3 is delivered Network meeting 2 Network meeting 2 is delivered Open Research Data Pilot (1) Research results are published Research results are published in peer-reviewed, open access journals and books Publications Peer reviewed articles (27) Uptake and anti-inflammatory effects of liposomal astaxanthin on endothelial cells tracked by Raman and fluorescence imaging Author(s): Radwan, Basseem Prabhakaran, Amrutha Rocchetti, Stefano Matuszyk, Ewelina Keyes, Tia E. Baranska, Malgorzata Published in: Microchim Acta, Issue 190, 2023, ISSN 0026-3672 Publisher: Springer Verlag DOI: 10.1007/s00604-023-05888-8 EdU sensing: The Raman way of following endothelial cell proliferation in vitro and ex vivo Author(s): Basseem Radwan; Stefano Rocchetti; Ewelina Matuszyk; Magdalena Sternak; Maciej Stodulski; Robert Pawlowski; Jacek Mlynarski; Krzysztof Brzozowski; Stefan Chlopicki; Malgorzata Baranska Published in: Biosensors and Bioelectronics, Issue 216, 2022, ISSN 0956-5663 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.bios.2022.114624 Combining nitric oxide and calcium sensing for the detection of endothelial dysfunction Author(s): Andreeva, Valeriia D. Ehlers, Haley R. C, Aswin Krishna Presselt, Martin J. Van Den Broek, Lenie Bonnet, Sylvestre Published in: Communications Chemistry, 2023, ISSN 2399-3669 Publisher: Springer DOI: 10.1038/s42004-023-00973-8 Radiative lifetime of a BODIPY dye as calculated by TDDFT and EOM-CCSD methods: solvent and vibronic effects Author(s): Rengel Cane E. Sia, Ruben Arturo Arellano-Reyes, Tia E. Keyes , Julien Guthmuller Published in: Physical Chemistry Chemical Physics, Issue 23, 2021, Page(s) 26324-26335, ISSN 1463-9084 Publisher: Royal Socienty of Chemistry DOI: 10.1039/d1cp03775g Interaction of Miltefosine with Microcavity Supported Lipid Membrane: Biophysical Insights from Electrochemical Impedance Spectroscopy Author(s): Nirod Kumar Sarangi, Amrutha Prabhakaran, Tia E. Keyes Published in: Electroanalysis, 2020, ISSN 1040-0397 Publisher: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/elan.202060424 Excited-State Dynamics in Borylated Arylisoquinoline Complexes in Solution and <i>in cellulo</i> Author(s): Yang, T. X. Valavalkar, A. Romero-Arenas, A. Dasgupta, A. Then, P. Chettri, A. Eggeling, C. Ros, A. Pischel, U. Dietzek-Ivansic, B. Published in: Chemistry-a European Journal, 2023, ISSN 0947-6539 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/chem.202203468 Monitoring excited-state relaxation in a molecular marker in live cells–a case study on astaxanthin Author(s): Tingxiang Yang, Avinash Chettri, Basseem Radwan, Ewelina Matuszyk, Malgorzata Baranska, Benjamin Dietzek Published in: Chemical Communications, 2021, ISSN 1359-7345 Publisher: Royal Society of Chemistry DOI: 10.1039/d1cc01907d Labeled vs. Label-Free Raman Imaging of Lipids in Endothelial Cells of Various Origins Author(s): Basseem Radwan; Adriana Adamczyk; Szymon Tott; Krzysztof Czamara; Katarzyna Kaminska; Ewelina Matuszyk; Malgorzata Baranska Published in: Molecules, Issue 25, 2020, Page(s) 5752-5760, ISSN 1420-3049 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules25235752 Multiplex Raman imaging of organelles in endothelial cells Author(s): Ewelina Matuszyk, Adriana Adamczyk, Basseem Radwan, Anna Pieczara, Piotr Szcześniak, Jacek Mlynarski, Katarzyna Kamińska, Malgorzata Baranska Published in: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Issue 255, 2021, Page(s) 119658, ISSN 1386-1425 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.saa.2021.119658 Using Biological Photophysics to Map the Excited‐State Topology of Molecular Photosensitizers for Photodynamic Therapy Author(s): Avinash Chettri; Tingxiang Yang; Houston D. Cole; Ge Shi; Colin G. Cameron; Sherri A. McFarland; Benjamin Dietzek‐Ivanšić Published in: Angewandte Chemie International Edition, Issue 62, 2023, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.202301452 A BODIPY‐Based Molecular Rotor in Giant Unilamellar Vesicles: A Case Study by Polarization‐Resolved Time‐Resolved Emission and Transient Absorption Spectroscopy Author(s): Keshav Kumar Jha; Amrutha Prabhakaran; Lukas Spantzel; Rengel Cane Sia; Iván Pérez; Ruben Arturo Arellano‐Reyes; Anna Elmanova; Anindita Dasgupta; Christian Eggeling; Michael Börsch; Julien Guthmuller; Martin Presselt; Tia E. Keyes; Benjamin Dietzek‐Ivanšić Published in: ChemPhotoChem, Issue 7, 2023, ISSN 2367-0932 Publisher: John Wiley & Sons, Ltd DOI: 10.1002/cptc.202300091 Langmuir-Blodgett Films of Diketopyrrolopyrroles with Tunable Amphiphilicity Author(s): Hupfer, M. L. Koszarna, B. Ghosh, S. Gryko, D. T. Presselt, M. Published in: Langmuir, 2021, ISSN 0743-7463 Publisher: American Chemical Society DOI: 10.1021/acs.langmuir.1c01113 Multimodal Investigation into the Interaction of Quinacrine with Microcavity-Supported Lipid Bilayers Author(s): Nirod Kumar Sarangi Amrutha Prabhakaran Tia E. Keyes Published in: Langmuir, Issue 38 (20), 2022, Page(s) 6411–6424, ISSN 0743-7463 Publisher: American Chemical Society DOI: 10.1021/acs.langmuir.2c00524 Triplet Formation and Triplet-Triplet Annihilation Upconversion in Iodine Substituted Non-Orthogonal BODIPY-Perylene Dyads Author(s): Jha, K. K. Prabhakaran, A. Sia, R. C. Reyes, R. A. A. Sarangi, N. K. Yang, T. X. Kumar, K. Kupfer, S. Guthmuller, J. Keyes, T. E. Dietzek-Ivansic, B. Published in: Chemphotochem, 2023, ISSN 2367-0932 Publisher: John Wiley & Sons DOI: 10.1002/cptc.202300073 Supramolecular Reorientation During Deposition Onto Metal Surfaces of Quasi-Two-Dimensional Langmuir Monolayers Composed of Bifunctional Amphiphilic, Twisted Perylenes Author(s): Hupfer, M. L. Meyer, R. Deckert-Gaudig, T. Ghosh, S. Skabeev, A. Peneva, K. Deckert, V. Dietzek, B. Presselt, M. Published in: Langmuir, Issue 37, 2021, ISSN 0743-7463 Publisher: American Chemical Society DOI: 10.1021/acs.langmuir.1c01525 In Cellulo Light‐Induced Dynamics in a BODIPY‐Perylene Dyad Author(s): Tingxiang Yang; Ruben Arturo Arellano-Reyes; Rhianne C. Curley; Keshav Kumar Jha; Avinash Chettri; Tia E. Keyes; Benjamin Dietzek-Ivanšić Published in: Chemistry – A European Journal, Issue 29, 2023, ISSN 0947-6539 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/chem.202300224 Shorter Alkyl Chains Enhance Molecular Diffusion and Electron Transfer Kinetics between Photosensitisers and Catalysts in CO2-Reducing Photocatalytic Liposomes Author(s): David M. Klein Dr. Santiago Rodríguez-Jiménez Marlene E. Hoefnagel Dr. Andrea Pannwitz Amrutha Prabhakaran Dr. Maxime A. Siegler Prof. Tia E. Keyes Prof. Erwin Reisner Prof. Albert M. Brouwer Prof. Sylvestre Bonnet Published in: Chemistry - A European Journnal, Issue 27, 2021, Page(s) 17203-17212, ISSN 1521-3765 Publisher: Wiley-VCH GmbH, Weinheim DOI: 10.1002/chem.202102989 Leaflet by Leaflet Synergistic Effects of Antimicrobial Peptides on Bacterial and Mammalian Membrane Models Author(s): Arpita Roy; Nirod Kumar Sarangi; Surajit Ghosh; Amrutha Prabhakaran; Tia E. Keyes Published in: The Journal of Physical Chemistry Letters, Issue 14, 2023, ISSN 1948-7185 Publisher: American Chemical Society DOI: 10.1021/acs.jpclett.3c00119 Toward Raman Subcellular Imaging of Endothelial Dysfunction Author(s): Adriana Adamczyk, Ewelina Matuszyk, Basseem Radwan, Stefano Rocchetti, Stefan Chlopicki, Malgorzata Baranska Published in: Journal of Medicinal Chemistry, Issue 64/8, 2021, Page(s) 4396-4409, ISSN 0022-2623 Publisher: American Chemical Society DOI: 10.1021/acs.jmedchem.1c00051 Dichroic Dipole Antenna Membranes from Aligned Linear BOPHY Dyes Author(s): Hupfer, M. L. Ghosh, S. Wang, Yingchun Opsomer, Tomas Dehaen, W. Presselt, M. Published in: Advanced Materials Interfaces, 2021, ISSN 2196-7350 Publisher: John Wiley & Sons DOI: 10.1002/admi.202101490 Astaxanthin as a new Raman probe for biosensing of specific subcellular lipidic structures: can we detect lipids in cells under resonance conditions? Author(s): Krzysztof Czamara, Adriana Adamczyk, Marta Stojak, Basseem Radwan, Malgorzata Baranska Published in: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X Publisher: Birkhauser Verlag DOI: 10.1007/s00018-020-03718-1 New Highly Sensitive and Specific Raman Probe for Live Cell Imaging of Mitochondrial Function Author(s): Pieczara, Anna Arellano Reyes, Ruben Arturo Keyes, Tia E. Dawiec, Patrycja Baranska, Malgorzata Published in: ACS Sensors, Issue 9, 2024, ISSN 2379-3694 Publisher: American Chemical Society DOI: 10.1021/acssensors.3c02576 BODIPY‐Perylene Charge Transfer Compounds; Sensitizers for Triplet‐Triplet Annihilation Up‐conversion Author(s): Ruben Arturo Arellano‐Reyes; Amrutha Prabhakaran; Rengel Cane E. Sia; Julien Guthmuller; Keshav Kumar Jha; Tingxiang Yang; Benjamin Dietzek‐Ivanšić; Vickie McKee; Tia E. Keyes Published in: Chemistry – A European Journal, Issue 29, 2023, ISSN 0947-6539 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/chem.202300239 Vascular inflammation on a chip: A scalable platform for trans-endothelial electrical resistance and immune cell migration Author(s): Haley, Ehlers; Arnaud, Nicolas; Frederik, Schavemaker; Jeroen P M, Heijmans; Martin, Bulst; Sebastiaan J, Trietsch; Lenie J, van den Broek Published in: Front Immunol, Issue 14, 2023, ISSN 1664-3224 Publisher: Frontiers Media S.A. DOI: 10.3389/fimmu.2023.1118624 Triplet–Triplet Annihilation Upconversion by Polymeric Sensitizers Author(s): Keshav Kumar Jha Amrutha Prabhakaran Christopher S. Burke Marcus Schulze Ulrich S. Schubert Tia E. Keyes Michael Jäger Benjamin Dietzek Ivanšić Published in: Journal of Physical Chemistry C, Issue 126, 2022, Page(s) 4057–4066, ISSN 1932-7447 Publisher: American Chemical Society DOI: 10.1021/acs.jpcc.1c09897 Bifacial Dye Membranes: Ultrathin and Free-Standing although not Being Covalently Bound Author(s): Hupfer, M. L. Dellith, J. Seyring, M. Diegel, M. Dellith, A. Ghosh, S. Rettenmayr, M. Dietzek-Ivansic, B. Presselt, M. Published in: Advanced Materials, 2023, ISSN 0935-9648 Publisher: United Nations Industrial Developement Organization DOI: 10.1002/adma.202204874 Evaluation of the passive permeability of antidepressants through pore-suspended lipid bilayer Author(s): Sarangi, Nirod Kumar Prabhakaran, Amrutha Roantree, Mark Keyes, Tia E. Published in: Colloids and Surfaces B: Biointerfaces, 2024, ISSN 0927-7765 Publisher: Elsevier BV DOI: 10.1016/j.colsurfb.2023.113688 Non-peer reviewed articles (2) Tracer-based metabolomics for profiling nitric oxide metabolites in a 3D microvessel-on-a-chip model Author(s): Pandian, Kanchana Huang, Luojiao Junaid, Abidemi Harms, Amy Van Zonneveld, Anton Jan Hankemeier, Thomas Published in: BioRXiv, 2023, ISSN 2692-8205 Publisher: bioRxiv DOI: 10.1101/2023.12.03.569402 Triplet-triplet annihilation upconversion for calcium sensing Author(s): Andreeva, Valeriia D. Yang, Tingxiang Regeni, Irene Dietzek-Ivanšić, Benjamin Bonnet, Sylvestre A. Published in: ChemRxiv, 2023, ISSN 2573-2293 Publisher: ChemRxiv DOI: 10.26434/chemrxiv-2023-7p1s5 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
