Training interdisciplinary glycoscientists to get a molecular-level grip on glycocodes at the human mucosa–microbiota interface

Project Information

SWEET CROSSTALK

Grant agreement ID: 814102

DOI

10.3030/814102

Project closed

EC signature date 30 August 2018

Start date 1 January 2019

End date 30 June 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 4 117 674,96

EU contribution

€ 4 117 674,96

Coordinated by

UNIVERSITEIT UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (3)

4 annual SCT network meetings
SB and SAB established
15 PhD theses: full drafts at 48 months for 3-year ESRs, first draft at 54 months for 4-year PhDs, see section 3.4.2)

15 PhD theses full drafts at 48 months for 3year ESRs first draft at 54 months for 4year PhDs see section 342

Websites, patent fillings, videos etc. (2)

Website
Science Slams

Documents, reports (1)

Min. 45 publications in peer-reviewed journals

Min 45 publications in peerreviewed journals

Publications

Peer reviewed articles (15)

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

Author(s): Paola Paone, Francesco Suriano, Ching Jian, Katri Korpela, Nathalie M. Delzenne, Matthias Van Hul, Anne Salonen & Patrice D. Cani
Published in: Gut Microbes, 2022, Page(s) 2152307, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2022.2152307

Human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and faecal proteome profiles in mice

Author(s): Paola Paone, Dimitris Latousakis, Romano Terrasi, Didier Vertommen, Ching Jian, Valentina Borlandelli, Francesco Suriano, Malin E V Johansson, Anthony Puel, Caroline Bouzin, Nathalie M. Delzenne, Anne Salonen, Nathalie Juge, Bogdan I. Florea, Giulio G. Muccioli, Herman S Overkleeft, Matthias Van Hul, Patrice D. Cani
Published in: GUT, 2024, ISSN 0017-5749
Publisher: BMJ Publishing Group
DOI: 10.1136/gutjnl-2023-330301

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

Author(s): Pedro J. Hernando, Simone Dedola, María J. Marín, Robert A. Field
Published in: Frontiers in Chemistry, 2021, ISSN 2296-2646
Publisher: Frontiers
DOI: 10.3389/fchem.2021.668509

Bacterial and Fungal Profiles as Markers of Infliximab Drug Response in Inflammatory Bowel Disease

Author(s): Rebecka Ventin-Holmberg, Anja Eberl, Schahzad Saqib, Katri Korpela, Seppo Virtanen, Taina Sipponen, Anne Salonen, Päivi Saavalainen, Eija Nissilä
Published in: Journal of Crohn's and Colitis, 2020, ISSN 1873-9946
Publisher: Elsevier Science
DOI: 10.1093/ecco-jcc/jjaa252

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Author(s): Molly D. Pither, Siobhán McClean, Alba Silipo, Antonio Molinaro, Flaviana Di Lorenzo
Published in: Glycoconjugate Journal, Issue 38/2, 2021, Page(s) 135-144, ISSN 0282-0080
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10719-020-09954-8

Solving the structural puzzle of bacterial glycome

Author(s): Roberta Marchetti, Rosa Ester Forgione, Ferran Nieto Fabregat, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo
Published in: Current Opinion in Structural Biology, Issue 68, 2021, Page(s) 74-83, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.003

Sensitive dipstick assays for lectin detection, based on glycan–BSA conjugate immobilisation on gold nanoparticles

Author(s): Pedro J. Hernando, Irina M. Ivanova, Simona Chessa, María J. Marín, Simone Dedola, Robert A. Field
Published in: Organic Chemistry Frontiers, 2023, ISSN 2052-4110
Publisher: The Royal Society of Chemistry
DOI: 10.1039/d3qo00424d

4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors

Author(s): Valentina Borlandelli, Dr. Zachary Armstrong, Dr. Alba Nin-Hill, Dr. Jeroen D. C. Codée, Dr. Lluís Raich, Dr. Marta Artola, Prof. Carme Rovira, Prof. Gideon J. Davies, Prof. Herman S. Overkleeft
Published in: ChemMedChem, 2022, ISSN 1860-7187
Publisher: Wiley-VCH
DOI: 10.1002/cmdc.202200580

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

Author(s): Paola Paone, Patrice D Cani
Published in: Gut, Issue 69/12, 2020, Page(s) 2232-2243, ISSN 0017-5749
Publisher: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-322260

Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

Author(s): Flaviana Di Lorenzo, Molly D. Pither, Michela Martufi, Ilaria Scarinci, Joan Guzmán-Caldentey, Ewelina Łakomiec, Wojciech Jachymek, Sven C. M. Bruijns, Sonsoles Martín Santamaría, Julia-Stephanie Frick, Yvette van Kooyk, Fabrizio Chiodo, Alba Silipo, Maria Lina Bernardini, Antonio Molinaro
Published in: ACS Central Science, Issue 6/9, 2020, Page(s) 1602-1616, ISSN 2374-7943
Publisher: ACS
DOI: 10.1021/acscentsci.0c00791

Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor

Author(s): Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. Marel, Jeroen D. C. Codée, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Published in: Angewandte Chemie International Edition, Issue 60/11, 2021, Page(s) 5754-5758, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202013920

Lipopolysaccharide from Gut‐Associated Lymphoid‐Tissue‐Resident Alcaligenes faecalis : Complete Structure Determination and Chemical Synthesis of Its Lipid A

Author(s): Atsushi Shimoyama, Flaviana Di Lorenzo, Haruki Yamaura, Keisuke Mizote, Angelo Palmigiano, Molly D. Pither, Immacolata Speciale, Tomoya Uto, Seiji Masui, Luisa Sturiale, Domenico Garozzo, Koji Hosomi, Naoko Shibata, Kazuya Kabayama, Yukari Fujimoto, Alba Silipo, Jun Kunisawa, Hiroshi Kiyono, Antonio Molinaro, Koichi Fukase
Published in: Angewandte Chemie International Edition, Issue 60/18, 2021, Page(s) 10023-10031, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202012374

The Peculiar Structure of Acetobacter pasteurianus CIP103108 LPS Core Oligosaccharide

Author(s): Roberta Marchetti, Ferran Nieto Fabregat, Mateusz Pallach, Djamel Gully, Eric Giraud, Antonio Molinaro, Katarzyna A. Duda, Alba Silipo
Published in: ChemBioChem, Issue 22/1, 2021, Page(s) 147-150, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000597

Selective Exoenzymatic Labeling of Lipooligosaccharides of Neisseria gonorrhoeae with α2,6-Sialoside Analogues

Author(s): Hanna de Jong, Maria J. Moure, Jet E. M. Hartman, Gerlof P. Bosman, Jun Yang Ong, Bart W. Bardoel, Geert-Jan Boons, Marc M. S. M. Wösten, Tom Wennekes
Published in: ChemBioChem, Issue Volume 23, Issue 19, 2022, Page(s) e202200340, ISSN 1439-7633
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cbic.202200340

The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221

Author(s): Molly Dorothy Pither, Giuseppe Mantova, Elena Scaglione, Chiara Pagliuca, Roberta Colicchio, Mariateresa Vitiello, Oleg V. Chernikov, Kuo-Feng Hua, Maxim S. Kokoulin , Alba Silipo , Paola Salvatore, Antonio Molinaro and Flaviana Di Lorenzo
Published in: Microorganisms, 2021, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms9122552

Book chapters (1)

Glycans in Bacterial Infections: Gram-Negative Infections in the Respiratory Tract

Author(s): Molly Dorothy Pither, Alba Silipo, Flaviana Di Lorenzo, Antonio Molinaro
Published in: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, ISBN 9780124095472
Publisher: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00055-9