Training interdisciplinary glycoscientists to get a molecular-level grip on glycocodes at the human mucosa–microbiota interface

Información del proyecto

SWEET CROSSTALK

Identificador del acuerdo de subvención: 814102

DOI

10.3030/814102

Proyecto cerrado

Fecha de la firma de la CE 30 Agosto 2018

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Junio 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 117 674,96

Aportación de la UE

€ 4 117 674,96

Coordinado por

UNIVERSITEIT UTRECHT
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (3)

4 annual SCT network meetings
SB and SAB established
15 PhD theses: full drafts at 48 months for 3-year ESRs, first draft at 54 months for 4-year PhDs, see section 3.4.2)

15 PhD theses full drafts at 48 months for 3year ESRs first draft at 54 months for 4year PhDs see section 342

Websites, patent fillings, videos etc. (2)

Website
Science Slams

Documents, reports (1)

Min. 45 publications in peer-reviewed journals

Min 45 publications in peerreviewed journals

Publicaciones

Peer reviewed articles (15)

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

Autores: Paola Paone, Francesco Suriano, Ching Jian, Katri Korpela, Nathalie M. Delzenne, Matthias Van Hul, Anne Salonen & Patrice D. Cani
Publicado en: Gut Microbes, 2022, Página(s) 2152307, ISSN 1949-0976
Editor: Landes Bioscience
DOI: 10.1080/19490976.2022.2152307

Human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and faecal proteome profiles in mice

Autores: Paola Paone, Dimitris Latousakis, Romano Terrasi, Didier Vertommen, Ching Jian, Valentina Borlandelli, Francesco Suriano, Malin E V Johansson, Anthony Puel, Caroline Bouzin, Nathalie M. Delzenne, Anne Salonen, Nathalie Juge, Bogdan I. Florea, Giulio G. Muccioli, Herman S Overkleeft, Matthias Van Hul, Patrice D. Cani
Publicado en: GUT, 2024, ISSN 0017-5749
Editor: BMJ Publishing Group
DOI: 10.1136/gutjnl-2023-330301

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

Autores: Pedro J. Hernando, Simone Dedola, María J. Marín, Robert A. Field
Publicado en: Frontiers in Chemistry, 2021, ISSN 2296-2646
Editor: Frontiers
DOI: 10.3389/fchem.2021.668509

Bacterial and Fungal Profiles as Markers of Infliximab Drug Response in Inflammatory Bowel Disease

Autores: Rebecka Ventin-Holmberg, Anja Eberl, Schahzad Saqib, Katri Korpela, Seppo Virtanen, Taina Sipponen, Anne Salonen, Päivi Saavalainen, Eija Nissilä
Publicado en: Journal of Crohn's and Colitis, 2020, ISSN 1873-9946
Editor: Elsevier Science
DOI: 10.1093/ecco-jcc/jjaa252

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Autores: Molly D. Pither, Siobhán McClean, Alba Silipo, Antonio Molinaro, Flaviana Di Lorenzo
Publicado en: Glycoconjugate Journal, Edición 38/2, 2021, Página(s) 135-144, ISSN 0282-0080
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10719-020-09954-8

Solving the structural puzzle of bacterial glycome

Autores: Roberta Marchetti, Rosa Ester Forgione, Ferran Nieto Fabregat, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo
Publicado en: Current Opinion in Structural Biology, Edición 68, 2021, Página(s) 74-83, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.003

Sensitive dipstick assays for lectin detection, based on glycan–BSA conjugate immobilisation on gold nanoparticles

Autores: Pedro J. Hernando, Irina M. Ivanova, Simona Chessa, María J. Marín, Simone Dedola, Robert A. Field
Publicado en: Organic Chemistry Frontiers, 2023, ISSN 2052-4110
Editor: The Royal Society of Chemistry
DOI: 10.1039/d3qo00424d

4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors

Autores: Valentina Borlandelli, Dr. Zachary Armstrong, Dr. Alba Nin-Hill, Dr. Jeroen D. C. Codée, Dr. Lluís Raich, Dr. Marta Artola, Prof. Carme Rovira, Prof. Gideon J. Davies, Prof. Herman S. Overkleeft
Publicado en: ChemMedChem, 2022, ISSN 1860-7187
Editor: Wiley-VCH
DOI: 10.1002/cmdc.202200580

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

Autores: Paola Paone, Patrice D Cani
Publicado en: Gut, Edición 69/12, 2020, Página(s) 2232-2243, ISSN 0017-5749
Editor: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-322260

Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

Autores: Flaviana Di Lorenzo, Molly D. Pither, Michela Martufi, Ilaria Scarinci, Joan Guzmán-Caldentey, Ewelina Łakomiec, Wojciech Jachymek, Sven C. M. Bruijns, Sonsoles Martín Santamaría, Julia-Stephanie Frick, Yvette van Kooyk, Fabrizio Chiodo, Alba Silipo, Maria Lina Bernardini, Antonio Molinaro
Publicado en: ACS Central Science, Edición 6/9, 2020, Página(s) 1602-1616, ISSN 2374-7943
Editor: ACS
DOI: 10.1021/acscentsci.0c00791

Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor

Autores: Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. Marel, Jeroen D. C. Codée, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Publicado en: Angewandte Chemie International Edition, Edición 60/11, 2021, Página(s) 5754-5758, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202013920

Lipopolysaccharide from Gut‐Associated Lymphoid‐Tissue‐Resident Alcaligenes faecalis : Complete Structure Determination and Chemical Synthesis of Its Lipid A

Autores: Atsushi Shimoyama, Flaviana Di Lorenzo, Haruki Yamaura, Keisuke Mizote, Angelo Palmigiano, Molly D. Pither, Immacolata Speciale, Tomoya Uto, Seiji Masui, Luisa Sturiale, Domenico Garozzo, Koji Hosomi, Naoko Shibata, Kazuya Kabayama, Yukari Fujimoto, Alba Silipo, Jun Kunisawa, Hiroshi Kiyono, Antonio Molinaro, Koichi Fukase
Publicado en: Angewandte Chemie International Edition, Edición 60/18, 2021, Página(s) 10023-10031, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202012374

The Peculiar Structure of Acetobacter pasteurianus CIP103108 LPS Core Oligosaccharide

Autores: Roberta Marchetti, Ferran Nieto Fabregat, Mateusz Pallach, Djamel Gully, Eric Giraud, Antonio Molinaro, Katarzyna A. Duda, Alba Silipo
Publicado en: ChemBioChem, Edición 22/1, 2021, Página(s) 147-150, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000597

Selective Exoenzymatic Labeling of Lipooligosaccharides of Neisseria gonorrhoeae with α2,6-Sialoside Analogues

Autores: Hanna de Jong, Maria J. Moure, Jet E. M. Hartman, Gerlof P. Bosman, Jun Yang Ong, Bart W. Bardoel, Geert-Jan Boons, Marc M. S. M. Wösten, Tom Wennekes
Publicado en: ChemBioChem, Edición Volume 23, Edición 19, 2022, Página(s) e202200340, ISSN 1439-7633
Editor: Wiley-VCH GmbH
DOI: 10.1002/cbic.202200340

The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221

Autores: Molly Dorothy Pither, Giuseppe Mantova, Elena Scaglione, Chiara Pagliuca, Roberta Colicchio, Mariateresa Vitiello, Oleg V. Chernikov, Kuo-Feng Hua, Maxim S. Kokoulin , Alba Silipo , Paola Salvatore, Antonio Molinaro and Flaviana Di Lorenzo
Publicado en: Microorganisms, 2021, ISSN 2076-2607
Editor: MDPI
DOI: 10.3390/microorganisms9122552

Book chapters (1)

Glycans in Bacterial Infections: Gram-Negative Infections in the Respiratory Tract

Autores: Molly Dorothy Pither, Alba Silipo, Flaviana Di Lorenzo, Antonio Molinaro
Publicado en: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, ISBN 9780124095472
Editor: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00055-9