Training interdisciplinary glycoscientists to get a molecular-level grip on glycocodes at the human mucosa–microbiota interface

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4 annual SCT network meetings
SB and SAB established
15 PhD theses: full drafts at 48 months for 3-year ESRs, first draft at 54 months for 4-year PhDs, see section 3.4.2)

15 PhD theses full drafts at 48 months for 3year ESRs first draft at 54 months for 4year PhDs see section 342

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Science Slams

Min. 45 publications in peer-reviewed journals

Min 45 publications in peerreviewed journals

Publications

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

Auteurs: Paola Paone, Francesco Suriano, Ching Jian, Katri Korpela, Nathalie M. Delzenne, Matthias Van Hul, Anne Salonen & Patrice D. Cani
Publié dans: Gut Microbes, 2022, Page(s) 2152307, ISSN 1949-0976
Éditeur: Landes Bioscience
DOI: 10.1080/19490976.2022.2152307

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

Auteurs: Pedro J. Hernando, Simone Dedola, María J. Marín, Robert A. Field
Publié dans: Frontiers in Chemistry, 2021, ISSN 2296-2646
Éditeur: Frontiers
DOI: 10.3389/fchem.2021.668509

Bacterial and Fungal Profiles as Markers of Infliximab Drug Response in Inflammatory Bowel Disease

Auteurs: Rebecka Ventin-Holmberg, Anja Eberl, Schahzad Saqib, Katri Korpela, Seppo Virtanen, Taina Sipponen, Anne Salonen, Päivi Saavalainen, Eija Nissilä
Publié dans: Journal of Crohn's and Colitis, 2020, ISSN 1873-9946
Éditeur: Elsevier Science
DOI: 10.1093/ecco-jcc/jjaa252

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Auteurs: Molly D. Pither, Siobhán McClean, Alba Silipo, Antonio Molinaro, Flaviana Di Lorenzo
Publié dans: Glycoconjugate Journal, Numéro 38/2, 2021, Page(s) 135-144, ISSN 0282-0080
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10719-020-09954-8

Solving the structural puzzle of bacterial glycome

Auteurs: Roberta Marchetti, Rosa Ester Forgione, Ferran Nieto Fabregat, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo
Publié dans: Current Opinion in Structural Biology, Numéro 68, 2021, Page(s) 74-83, ISSN 0959-440X
Éditeur: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.003

Sensitive dipstick assays for lectin detection, based on glycan–BSA conjugate immobilisation on gold nanoparticles

Auteurs: Pedro J. Hernando, Irina M. Ivanova, Simona Chessa, María J. Marín, Simone Dedola, Robert A. Field
Publié dans: Organic Chemistry Frontiers, 2023, ISSN 2052-4110
Éditeur: The Royal Society of Chemistry
DOI: 10.1039/d3qo00424d

4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors

Auteurs: Valentina Borlandelli, Dr. Zachary Armstrong, Dr. Alba Nin-Hill, Dr. Jeroen D. C. Codée, Dr. Lluís Raich, Dr. Marta Artola, Prof. Carme Rovira, Prof. Gideon J. Davies, Prof. Herman S. Overkleeft
Publié dans: ChemMedChem, 2022, ISSN 1860-7187
Éditeur: Wiley-VCH
DOI: 10.1002/cmdc.202200580

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

Auteurs: Paola Paone, Patrice D Cani
Publié dans: Gut, Numéro 69/12, 2020, Page(s) 2232-2243, ISSN 0017-5749
Éditeur: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-322260

Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

Auteurs: Flaviana Di Lorenzo, Molly D. Pither, Michela Martufi, Ilaria Scarinci, Joan Guzmán-Caldentey, Ewelina Łakomiec, Wojciech Jachymek, Sven C. M. Bruijns, Sonsoles Martín Santamaría, Julia-Stephanie Frick, Yvette van Kooyk, Fabrizio Chiodo, Alba Silipo, Maria Lina Bernardini, Antonio Molinaro
Publié dans: ACS Central Science, Numéro 6/9, 2020, Page(s) 1602-1616, ISSN 2374-7943
Éditeur: ACS
DOI: 10.1021/acscentsci.0c00791

Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor

Auteurs: Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. Marel, Jeroen D. C. Codée, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Publié dans: Angewandte Chemie International Edition, Numéro 60/11, 2021, Page(s) 5754-5758, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202013920

Lipopolysaccharide from Gut‐Associated Lymphoid‐Tissue‐Resident Alcaligenes faecalis : Complete Structure Determination and Chemical Synthesis of Its Lipid A

Auteurs: Atsushi Shimoyama, Flaviana Di Lorenzo, Haruki Yamaura, Keisuke Mizote, Angelo Palmigiano, Molly D. Pither, Immacolata Speciale, Tomoya Uto, Seiji Masui, Luisa Sturiale, Domenico Garozzo, Koji Hosomi, Naoko Shibata, Kazuya Kabayama, Yukari Fujimoto, Alba Silipo, Jun Kunisawa, Hiroshi Kiyono, Antonio Molinaro, Koichi Fukase
Publié dans: Angewandte Chemie International Edition, Numéro 60/18, 2021, Page(s) 10023-10031, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202012374

The Peculiar Structure of Acetobacter pasteurianus CIP103108 LPS Core Oligosaccharide

Auteurs: Roberta Marchetti, Ferran Nieto Fabregat, Mateusz Pallach, Djamel Gully, Eric Giraud, Antonio Molinaro, Katarzyna A. Duda, Alba Silipo
Publié dans: ChemBioChem, Numéro 22/1, 2021, Page(s) 147-150, ISSN 1439-4227
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000597

Selective Exoenzymatic Labeling of Lipooligosaccharides of Neisseria gonorrhoeae with α2,6-Sialoside Analogues

Auteurs: Hanna de Jong, Maria J. Moure, Jet E. M. Hartman, Gerlof P. Bosman, Jun Yang Ong, Bart W. Bardoel, Geert-Jan Boons, Marc M. S. M. Wösten, Tom Wennekes
Publié dans: ChemBioChem, Numéro Volume 23, Numéro 19, 2022, Page(s) e202200340, ISSN 1439-7633
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/cbic.202200340

The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221

Auteurs: Molly Dorothy Pither, Giuseppe Mantova, Elena Scaglione, Chiara Pagliuca, Roberta Colicchio, Mariateresa Vitiello, Oleg V. Chernikov, Kuo-Feng Hua, Maxim S. Kokoulin , Alba Silipo , Paola Salvatore, Antonio Molinaro and Flaviana Di Lorenzo
Publié dans: Microorganisms, 2021, ISSN 2076-2607
Éditeur: MDPI
DOI: 10.3390/microorganisms9122552

Glycans in Bacterial Infections: Gram-Negative Infections in the Respiratory Tract

Auteurs: Molly Dorothy Pither, Alba Silipo, Flaviana Di Lorenzo, Antonio Molinaro
Publié dans: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, ISBN 9780124095472
Éditeur: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00055-9

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