Training interdisciplinary glycoscientists to get a molecular-level grip on glycocodes at the human mucosa–microbiota interface

Risultati finali

4 annual SCT network meetings
SB and SAB established
15 PhD theses: full drafts at 48 months for 3-year ESRs, first draft at 54 months for 4-year PhDs, see section 3.4.2)

15 PhD theses full drafts at 48 months for 3year ESRs first draft at 54 months for 4year PhDs see section 342

Website
Science Slams

Min. 45 publications in peer-reviewed journals

Min 45 publications in peerreviewed journals

Pubblicazioni

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

Autori: Paola Paone, Francesco Suriano, Ching Jian, Katri Korpela, Nathalie M. Delzenne, Matthias Van Hul, Anne Salonen & Patrice D. Cani
Pubblicato in: Gut Microbes, 2022, Pagina/e 2152307, ISSN 1949-0976
Editore: Landes Bioscience
DOI: 10.1080/19490976.2022.2152307

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

Autori: Pedro J. Hernando, Simone Dedola, María J. Marín, Robert A. Field
Pubblicato in: Frontiers in Chemistry, 2021, ISSN 2296-2646
Editore: Frontiers
DOI: 10.3389/fchem.2021.668509

Bacterial and Fungal Profiles as Markers of Infliximab Drug Response in Inflammatory Bowel Disease

Autori: Rebecka Ventin-Holmberg, Anja Eberl, Schahzad Saqib, Katri Korpela, Seppo Virtanen, Taina Sipponen, Anne Salonen, Päivi Saavalainen, Eija Nissilä
Pubblicato in: Journal of Crohn's and Colitis, 2020, ISSN 1873-9946
Editore: Elsevier Science
DOI: 10.1093/ecco-jcc/jjaa252

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Autori: Molly D. Pither, Siobhán McClean, Alba Silipo, Antonio Molinaro, Flaviana Di Lorenzo
Pubblicato in: Glycoconjugate Journal, Numero 38/2, 2021, Pagina/e 135-144, ISSN 0282-0080
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10719-020-09954-8

Solving the structural puzzle of bacterial glycome

Autori: Roberta Marchetti, Rosa Ester Forgione, Ferran Nieto Fabregat, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo
Pubblicato in: Current Opinion in Structural Biology, Numero 68, 2021, Pagina/e 74-83, ISSN 0959-440X
Editore: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.003

Sensitive dipstick assays for lectin detection, based on glycan–BSA conjugate immobilisation on gold nanoparticles

Autori: Pedro J. Hernando, Irina M. Ivanova, Simona Chessa, María J. Marín, Simone Dedola, Robert A. Field
Pubblicato in: Organic Chemistry Frontiers, 2023, ISSN 2052-4110
Editore: The Royal Society of Chemistry
DOI: 10.1039/d3qo00424d

4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors

Autori: Valentina Borlandelli, Dr. Zachary Armstrong, Dr. Alba Nin-Hill, Dr. Jeroen D. C. Codée, Dr. Lluís Raich, Dr. Marta Artola, Prof. Carme Rovira, Prof. Gideon J. Davies, Prof. Herman S. Overkleeft
Pubblicato in: ChemMedChem, 2022, ISSN 1860-7187
Editore: Wiley-VCH
DOI: 10.1002/cmdc.202200580

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

Autori: Paola Paone, Patrice D Cani
Pubblicato in: Gut, Numero 69/12, 2020, Pagina/e 2232-2243, ISSN 0017-5749
Editore: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-322260

Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

Autori: Flaviana Di Lorenzo, Molly D. Pither, Michela Martufi, Ilaria Scarinci, Joan Guzmán-Caldentey, Ewelina Łakomiec, Wojciech Jachymek, Sven C. M. Bruijns, Sonsoles Martín Santamaría, Julia-Stephanie Frick, Yvette van Kooyk, Fabrizio Chiodo, Alba Silipo, Maria Lina Bernardini, Antonio Molinaro
Pubblicato in: ACS Central Science, Numero 6/9, 2020, Pagina/e 1602-1616, ISSN 2374-7943
Editore: ACS
DOI: 10.1021/acscentsci.0c00791

Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor

Autori: Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. Marel, Jeroen D. C. Codée, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Pubblicato in: Angewandte Chemie International Edition, Numero 60/11, 2021, Pagina/e 5754-5758, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202013920

Lipopolysaccharide from Gut‐Associated Lymphoid‐Tissue‐Resident Alcaligenes faecalis : Complete Structure Determination and Chemical Synthesis of Its Lipid A

Autori: Atsushi Shimoyama, Flaviana Di Lorenzo, Haruki Yamaura, Keisuke Mizote, Angelo Palmigiano, Molly D. Pither, Immacolata Speciale, Tomoya Uto, Seiji Masui, Luisa Sturiale, Domenico Garozzo, Koji Hosomi, Naoko Shibata, Kazuya Kabayama, Yukari Fujimoto, Alba Silipo, Jun Kunisawa, Hiroshi Kiyono, Antonio Molinaro, Koichi Fukase
Pubblicato in: Angewandte Chemie International Edition, Numero 60/18, 2021, Pagina/e 10023-10031, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202012374

The Peculiar Structure of Acetobacter pasteurianus CIP103108 LPS Core Oligosaccharide

Autori: Roberta Marchetti, Ferran Nieto Fabregat, Mateusz Pallach, Djamel Gully, Eric Giraud, Antonio Molinaro, Katarzyna A. Duda, Alba Silipo
Pubblicato in: ChemBioChem, Numero 22/1, 2021, Pagina/e 147-150, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000597

Selective Exoenzymatic Labeling of Lipooligosaccharides of Neisseria gonorrhoeae with α2,6-Sialoside Analogues

Autori: Hanna de Jong, Maria J. Moure, Jet E. M. Hartman, Gerlof P. Bosman, Jun Yang Ong, Bart W. Bardoel, Geert-Jan Boons, Marc M. S. M. Wösten, Tom Wennekes
Pubblicato in: ChemBioChem, Numero Volume 23, Numero 19, 2022, Pagina/e e202200340, ISSN 1439-7633
Editore: Wiley-VCH GmbH
DOI: 10.1002/cbic.202200340

The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221

Autori: Molly Dorothy Pither, Giuseppe Mantova, Elena Scaglione, Chiara Pagliuca, Roberta Colicchio, Mariateresa Vitiello, Oleg V. Chernikov, Kuo-Feng Hua, Maxim S. Kokoulin , Alba Silipo , Paola Salvatore, Antonio Molinaro and Flaviana Di Lorenzo
Pubblicato in: Microorganisms, 2021, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms9122552

Glycans in Bacterial Infections: Gram-Negative Infections in the Respiratory Tract

Autori: Molly Dorothy Pither, Alba Silipo, Flaviana Di Lorenzo, Antonio Molinaro
Pubblicato in: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, ISBN 9780124095472
Editore: Elsevier
DOI: 10.1016/b978-0-12-819475-1.00055-9

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