Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase 1 trial in Europe and sub-Saharan Africa

Project Information

Vacc-iNTS

Grant agreement ID: 815439

DOI

10.3030/815439

EC signature date 30 April 2019

Start date 1 October 2019

End date 31 July 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

No data

EU contribution

€ 6 871 188,73

Coordinated by

SCLAVO VACCINES ASSOCIATION
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan (DMP)

Websites, patent fillings, videos etc. (1)

Project website

Documents, reports (1)

Report on stakeholders meeting

Publications

Peer reviewed articles (12)

Complications and mortality of non-typhoidal salmonella invasive disease: a global systematic review and meta-analysis

Author(s): Christian S Marchello, PhD Megan Birkhold, MD Prof John A Crump, MD on behalf of theVacc-iNTS consortium collaborators
Published in: The Lancet Infectious Diseases, Issue 01406736, 2022, Page(s) P692-705, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(21)00615-0

Nontyphoidal Salmonella Invasive Disease: Challenges and Solutions

Author(s): John A Crump, Tonney S Nyirenda, Lisette Mbuyi Kalonji, Marie-France Phoba, Bieke Tack, James A Platts-Mills, Melita A Gordon, Samuel M Kariuki
Published in: Open Forum Infectious Diseases, Issue Volume 10, Issue Supplement_1, May 2023, 2023, Page(s) S32–S37, ISSN 2328-8957
Publisher: Oxford University Press on behalf of Infectious Diseases Society of America.
DOI: 10.1093/ofid/ofad020

Prevalence and distribution of non-typhoidal<i>Salmonella enterica</i>serogroups and serovars isolated from normally sterile sites: a global systematic review

Author(s): Nienke N. Hagedoorn; Shruti Murthy; Megan Birkhold; Christian S. Marchello; John A. Crump
Published in: Crossref, Issue 3, 2024, ISSN 1469-4409
Publisher: Cambridge Press
DOI: 10.1101/2023.06.13.23291315

Characterization of Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-Antigens in Human Sera

Author(s): Aruta MG, Lari E, De Simone D, Semplici B, Semplici C, Dale H, Chirwa E, Kadwala I, Mbewe M, Banda H, Iturriza-Gomara M, Gordon M, Nyirenda T, Piu P, Pizza M, Berlanda Scroza F, Grappi S, Canals R, Rossi O; Vacc-iNTS consortium collaborators.
Published in: BioTech., Issue 12(3), 2023, Page(s) 54., ISSN 2673-6284
Publisher: MDPI
DOI: 10.3390/biotech12030054

Direct association between rainfall and non-typhoidal Salmonella bloodstream infections in hospital-admitted children in the Democratic Republic of Congo

Author(s): Bieke Tack, Daniel Vita, Marie-France Phoba, Lisette Mbuyi-Kalonji, Liselotte Hardy, Barbara Barbé, Jan Jacobs, Octavie Lunguya & Liesbet Jacobs
Published in: Scientific Reports, Issue 20452322, 2021, Page(s) 21617, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-01030-x

Development and Characterization of a Luminescence-Based High-Throughput Serum Bactericidal Assay (L-SBA) to Assess Bactericidal Activity of Human Sera against Nontyphoidal Salmonella

Author(s): Aruta, Maria Grazia, Daniele De Simone, Helen Dale, Esmelda Chirwa, Innocent Kadwala, Maurice Mbewe, Happy Banda, Melita Gordon, Mariagrazia Pizza, Francesco Berlanda Scorza, and et al.
Published in: Methods and Protocols., 2023, Page(s) 100, ISSN 2409-9279
Publisher: MDPI
DOI: 10.3390/mps5060100

<i>Salmonella</i>Vaccine Study in Oxford (SALVO) trial: protocol for an observer-participant blind randomised placebo-controlled trial of the iNTS-GMMA vaccine within a European cohort

Author(s): Brama Hanumunthadu; Nasir Kanji; Nelly Owino; Carla Ferreira Da Silva; Hannah Robinson; Rachel White; Pietro Ferruzzi; Usman Nakakana; Rocio Canals; Andrew J Pollard; Maheshi Ramasamy
Published in: Crossref, Issue 3, 2023, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2023-072938

Health itinerary-related survival of children under-five with severe malaria or bloodstream infection, DR Congo

Author(s): Tack B, Vita D, Nketo J, Wasolua N, Ndengila N, Herssens N, et al
Published in: PLoS Negl Trop Dis, Issue 17(3), 2023, Page(s) e0011156., ISSN 1935-2735
Publisher: Plos Public Library of Science
DOI: 10.1371/journal.pntd.0011156

Incidence of non-typhoidal Salmonella invasive disease: A systematic review and meta-analysis

Author(s): Marchello CS, Fiorino F, Pettini E, Crump JA; Vacc-iNTS Consortium Collaborators.
Published in: J Infect., Issue 15322742, 2021, ISSN 1532-2742
Publisher: Elsevier Lsd
DOI: 10.1016/j.jinf.2021.06.029

Performance of Automated Point-of-Care Respiratory Rate Counting versus Manual Counting in Children under Five Admitted with Severe Febrile Illness to Kisantu Hospital, DR Congo

Author(s): Tack, B.; Vita, D.; Mbaki, T.N.; Lunguya, O.; Toelen, J.; Jacobs, J.
Published in: Diagnostics, Issue 20754418, 2021, Page(s) 2078, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics11112078

Epidemiological cut-off value and antibiotic susceptibility test methods for azithromycin in a collection of multi-country invasive non-typhoidal Salmonella

Author(s): Tack B, Phoba MF, Thong P, Lompo P, Hupko C, Desmet S, Martiny D, Mattheus W, Pardos de la Gandara M, Mbuyi-Kalonji L, Kuijpers L, Prevost B, Barbé B, Vandenberg O, Lunguya O, Ruiz J, Jacobs J, Hardy L.
Published in: Clin Microbiol Infect., Issue Dec;28(12), 2022, Page(s) 1615-1623, ISSN 1469-0691
Publisher: Elsevier
DOI: 10.1016/j.cmi.2022.06.009

Field Experiences with Handheld Diagnostic Devices to Triage Children under Five Presenting with Severe Febrile Illness in a District Hospital in DR Congo

Author(s): Bieke Tack, Daniel Vita, Irène Mansosa, Thomas Nsema Mbaki, Naomie Wasolua, Aimée Luyindula, Jaan Toelen, Octavie Lunguya, Jan Jacobs
Published in: Diagnostics, Issue 20754418, 2022, Page(s) 746, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics12030746

Other (2)

Understanding the epidemiology of iNTS disease in Africa in preparation for future iNTS- vaccine studies in endemic countries: Seroepidemiology in Africa of iNTS (SAiNTS) Study Protocol [Version 9.0]

Author(s): Melita Gordon; Marc Henrion; Helen Dale
Published in: Crossref, Issue 2, 2023
Publisher: Wellcome Open Research
DOI: 10.12688/wellcomeopenres.18054.1

Effectiveness of iNTS vaccination in Sub-Saharan Africa

Author(s): Cassese, Daniele; Dimitri, Nicola; Breghi, Gianluca; Spadafina, Tiziana
Published in: Issue 3, 2023
Publisher: arXiv
DOI: 10.48550/arxiv.2303.18036