Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase 1 trial in Europe and sub-Saharan Africa

Información del proyecto

Vacc-iNTS

Identificador del acuerdo de subvención: 815439

DOI

10.3030/815439

Fecha de la firma de la CE 30 Abril 2019

Fecha de inicio 1 Octubre 2019

Fecha de finalización 31 Julio 2026

Financiado con arreglo a

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coste total

Sin datos

Aportación de la UE

€ 6 871 188,73

Coordinado por

SCLAVO VACCINES ASSOCIATION
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan (DMP)

Websites, patent fillings, videos etc. (1)

Project website

Documents, reports (1)

Report on stakeholders meeting

Publicaciones

Peer reviewed articles (12)

Complications and mortality of non-typhoidal salmonella invasive disease: a global systematic review and meta-analysis

Autores: Christian S Marchello, PhD Megan Birkhold, MD Prof John A Crump, MD on behalf of theVacc-iNTS consortium collaborators
Publicado en: The Lancet Infectious Diseases, Edición 01406736, 2022, Página(s) P692-705, ISSN 0140-6736
Editor: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(21)00615-0

Nontyphoidal Salmonella Invasive Disease: Challenges and Solutions

Autores: John A Crump, Tonney S Nyirenda, Lisette Mbuyi Kalonji, Marie-France Phoba, Bieke Tack, James A Platts-Mills, Melita A Gordon, Samuel M Kariuki
Publicado en: Open Forum Infectious Diseases, Edición Volume 10, Edición Supplement_1, May 2023, 2023, Página(s) S32–S37, ISSN 2328-8957
Editor: Oxford University Press on behalf of Infectious Diseases Society of America.
DOI: 10.1093/ofid/ofad020

Prevalence and distribution of non-typhoidal<i>Salmonella enterica</i>serogroups and serovars isolated from normally sterile sites: a global systematic review

Autores: Nienke N. Hagedoorn; Shruti Murthy; Megan Birkhold; Christian S. Marchello; John A. Crump
Publicado en: Crossref, Edición 3, 2024, ISSN 1469-4409
Editor: Cambridge Press
DOI: 10.1101/2023.06.13.23291315

Characterization of Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-Antigens in Human Sera

Autores: Aruta MG, Lari E, De Simone D, Semplici B, Semplici C, Dale H, Chirwa E, Kadwala I, Mbewe M, Banda H, Iturriza-Gomara M, Gordon M, Nyirenda T, Piu P, Pizza M, Berlanda Scroza F, Grappi S, Canals R, Rossi O; Vacc-iNTS consortium collaborators.
Publicado en: BioTech., Edición 12(3), 2023, Página(s) 54., ISSN 2673-6284
Editor: MDPI
DOI: 10.3390/biotech12030054

Direct association between rainfall and non-typhoidal Salmonella bloodstream infections in hospital-admitted children in the Democratic Republic of Congo

Autores: Bieke Tack, Daniel Vita, Marie-France Phoba, Lisette Mbuyi-Kalonji, Liselotte Hardy, Barbara Barbé, Jan Jacobs, Octavie Lunguya & Liesbet Jacobs
Publicado en: Scientific Reports, Edición 20452322, 2021, Página(s) 21617, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-01030-x

Development and Characterization of a Luminescence-Based High-Throughput Serum Bactericidal Assay (L-SBA) to Assess Bactericidal Activity of Human Sera against Nontyphoidal Salmonella

Autores: Aruta, Maria Grazia, Daniele De Simone, Helen Dale, Esmelda Chirwa, Innocent Kadwala, Maurice Mbewe, Happy Banda, Melita Gordon, Mariagrazia Pizza, Francesco Berlanda Scorza, and et al.
Publicado en: Methods and Protocols., 2023, Página(s) 100, ISSN 2409-9279
Editor: MDPI
DOI: 10.3390/mps5060100

<i>Salmonella</i>Vaccine Study in Oxford (SALVO) trial: protocol for an observer-participant blind randomised placebo-controlled trial of the iNTS-GMMA vaccine within a European cohort

Autores: Brama Hanumunthadu; Nasir Kanji; Nelly Owino; Carla Ferreira Da Silva; Hannah Robinson; Rachel White; Pietro Ferruzzi; Usman Nakakana; Rocio Canals; Andrew J Pollard; Maheshi Ramasamy
Publicado en: Crossref, Edición 3, 2023, ISSN 2044-6055
Editor: BMJ Publishing Group
DOI: 10.1136/bmjopen-2023-072938

Health itinerary-related survival of children under-five with severe malaria or bloodstream infection, DR Congo

Autores: Tack B, Vita D, Nketo J, Wasolua N, Ndengila N, Herssens N, et al
Publicado en: PLoS Negl Trop Dis, Edición 17(3), 2023, Página(s) e0011156., ISSN 1935-2735
Editor: Plos Public Library of Science
DOI: 10.1371/journal.pntd.0011156

Incidence of non-typhoidal Salmonella invasive disease: A systematic review and meta-analysis

Autores: Marchello CS, Fiorino F, Pettini E, Crump JA; Vacc-iNTS Consortium Collaborators.
Publicado en: J Infect., Edición 15322742, 2021, ISSN 1532-2742
Editor: Elsevier Lsd
DOI: 10.1016/j.jinf.2021.06.029

Performance of Automated Point-of-Care Respiratory Rate Counting versus Manual Counting in Children under Five Admitted with Severe Febrile Illness to Kisantu Hospital, DR Congo

Autores: Tack, B.; Vita, D.; Mbaki, T.N.; Lunguya, O.; Toelen, J.; Jacobs, J.
Publicado en: Diagnostics, Edición 20754418, 2021, Página(s) 2078, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/diagnostics11112078

Epidemiological cut-off value and antibiotic susceptibility test methods for azithromycin in a collection of multi-country invasive non-typhoidal Salmonella

Autores: Tack B, Phoba MF, Thong P, Lompo P, Hupko C, Desmet S, Martiny D, Mattheus W, Pardos de la Gandara M, Mbuyi-Kalonji L, Kuijpers L, Prevost B, Barbé B, Vandenberg O, Lunguya O, Ruiz J, Jacobs J, Hardy L.
Publicado en: Clin Microbiol Infect., Edición Dec;28(12), 2022, Página(s) 1615-1623, ISSN 1469-0691
Editor: Elsevier
DOI: 10.1016/j.cmi.2022.06.009

Field Experiences with Handheld Diagnostic Devices to Triage Children under Five Presenting with Severe Febrile Illness in a District Hospital in DR Congo

Autores: Bieke Tack, Daniel Vita, Irène Mansosa, Thomas Nsema Mbaki, Naomie Wasolua, Aimée Luyindula, Jaan Toelen, Octavie Lunguya, Jan Jacobs
Publicado en: Diagnostics, Edición 20754418, 2022, Página(s) 746, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/diagnostics12030746

Other (2)

Understanding the epidemiology of iNTS disease in Africa in preparation for future iNTS- vaccine studies in endemic countries: Seroepidemiology in Africa of iNTS (SAiNTS) Study Protocol [Version 9.0]

Autores: Melita Gordon; Marc Henrion; Helen Dale
Publicado en: Crossref, Edición 2, 2023
Editor: Wellcome Open Research
DOI: 10.12688/wellcomeopenres.18054.1

Effectiveness of iNTS vaccination in Sub-Saharan Africa

Autores: Cassese, Daniele; Dimitri, Nicola; Breghi, Gianluca; Spadafina, Tiziana
Publicado en: Edición 3, 2023
Editor: arXiv
DOI: 10.48550/arxiv.2303.18036