A bio-identical and non-animal replacement for the quality control reagent of pyrogen testing in the medical and pharmaceutical industries.

Project description

Towards more sustainable endotoxin testing

Bacteria produce lipopolysaccharides, which may induce strong immune reactions including fever and shock. This is why all pharmaceutical products undergo rigorous endotoxin or pyrogen testing. The gold standard method involves the reagent Limulus amoebocyte lysate (LAL), which is extracted from the horseshoe crab, Limulus polyphemus. The aim of the EU-funded LimuleX project is to address the growing demand for LAL in a sustainable manner. Using proprietary cell technology, researchers have succeeded in producing a bio-identical LAL reagent in an animal-free manner. Moreover, the LimuleX LAL reagent constitutes a better-quality product and is in line with the animal replacement, reduction and refinement principles.

Fields of science

• natural sciences › biological sciences › microbiology › bacteriology
• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs
• natural sciences › biological sciences › biochemistry › biomolecules
• social sciences › economics and business › business and management › business models
• medical and health sciences › medical biotechnology › cells technologies

Programme(s)

• H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs Main Programme
• H2020-EU.3. - PRIORITY 'Societal challenges
• H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies

Topic(s)

• EIC-SMEInst-2018-2020 - SME instrument

Call for proposal

H2020-EIC-SMEInst-2018-2020

See other projects for this call

Sub call

H2020-SMEInst-2018-2020-1

Funding Scheme

SME-1 - SME instrument phase 1

Coordinator

SOTHIC BIOSCIENCE LIMITED

Net EU contribution

€ 50 000,00

Address

Buckley Kiely Heritage Business Park Mahon Industr Estate
T12 P1HX Blackrock Cork
Ireland

Region

Ireland › Southern › South-West

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Links

Other funding

€ 21 429,00