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Exploring the Epigenome by Multiplexed Physical Mapping of Individual Chromosomes


Multimodal single-molecule microscopy with continuously controlled spectral resolution

Author(s): Jonathan Jeffet; Ariel Ionescu; Yael Michaeli; Dmitry Torchinsky; Eran Perlson; Timothy D. Craggs; Yuval Ebenstein
Published in: Biophysical Journal, Issue 1, 2021, ISSN 2667-0747
Publisher: Elsevier BV
DOI: 10.1016/j.bpr.2021.100013

From single-molecule to genome-wide mapping of DNA lesions: repair-assisted damage detection sequencing

Author(s): Noa Gilat, Dena Fridman, Hila Sharim, Sapir Margalit, Natalie R. Gassman, Yael Michaeli, Yuval Ebenstein
Published in: Biophysical Reports, 2021, ISSN 2667-0747
Publisher: The Biophysical Society
DOI: 10.1016/j.bpr.2021.100017

Long reads capture simultaneous enhancer-promoter methylation status for cell-type deconvolution

Author(s): Sapir Margalit, Yotam Abramson, Hila Sharim, Zohar Manber, Surajit Bhattacharya, Yi-Wen Chen, Eric Vilain, Hayk Barseghyan, Ran Elkon, Roded Sharan, Yuval Ebenstein
Published in: Bioinformatics, 2021, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btab306

Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

Author(s): Tslil Gabrieli, Yael Michaeli, Sigal Avraham, Dmitry Torchinsky, Sapir Margalit, Leonie Schutz, Matyas Juhasz, Ceyda Coruh, Nissim Arbib, Zhaohui Sunny Zhou, Julie A. Law, Elmar Weinhold and Yuval Ebenstein
Published in: Nucleic Acids Research, 2022, ISSN 1362-4962
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac460

Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale

Author(s): Jonathan Jeffet, Sapir Margalit, Yael Michaeli, Yuval Ebenstein
Published in: Essays in Biochemistry, Issue 65/1, 2021, Page(s) 51-66, ISSN 0071-1365
Publisher: Portland Press, Ltd.
DOI: 10.1042/ebc20200021

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