Exploring the Epigenome by Multiplexed Physical Mapping of Individual Chromosomes

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Dam Assisted Fluorescent Tagging of Chromatin Accessibility (DAFCA) for Optical Genome Mapping in Nanochannel Arrays

Autores: Gil Nifker; Assaf Grunwald; Sapir Margalit; Zuzana Tulpova; Yael Michaeli; Hagai Har-Gil; Noy Maimon; Elad Roichman; Leonie Schütz; Elmar Weinhold; Yuval Ebenstein
Publicado en: ACS nano 17(10), 9178-9187 (2023). doi:10.1021/acsnano.2c12755, Edición 4, 2023, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.2c12755

Multimodal single-molecule microscopy with continuously controlled spectral resolution

Autores: Jonathan Jeffet; Ariel Ionescu; Yael Michaeli; Dmitry Torchinsky; Eran Perlson; Timothy D. Craggs; Yuval Ebenstein
Publicado en: Biophysical Journal, Edición 1, 2021, ISSN 2667-0747
Editor: Elsevier BV
DOI: 10.1016/j.bpr.2021.100013

From single-molecule to genome-wide mapping of DNA lesions: repair-assisted damage detection sequencing

Autores: Noa Gilat, Dena Fridman, Hila Sharim, Sapir Margalit, Natalie R. Gassman, Yael Michaeli, Yuval Ebenstein
Publicado en: Biophysical Reports, 2021, ISSN 2667-0747
Editor: The Biophysical Society
DOI: 10.1016/j.bpr.2021.100017

Long-read structural and epigenetic profiling of a kidney tumor-matched sample with nanopore sequencing and optical genome mapping

Autores: Sapir Margalit, Zuzana Tulpová, Tahir Detinis Zur, Yael Michaeli, Jasline Deek, Gil Nifker, Rita Haldar, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Hagit Baris Feldman, Assaf Grunwald, Yuval Ebenstein
Publicado en: NAR Genomics and Bioinformatics, Edición 7, 2025, ISSN 2631-9268
Editor: Oxford University Press (OUP)
DOI: 10.1093/nargab/lqae190

Optical genome and epigenome mapping of clear cell renal cell carcinoma

Autores: Sapir Margalit, Zuzana Tulpová, Yael Michaeli, Tahir Detinis Zur, Jasline Deek, Sivan Louzoun-Zada, Gil Nifker, Assaf Grunwald, Yuval Scher, Leonie Schütz, Elmar Weinhold, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Eitan Friedman, Yuval Ebenstein
Publicado en: NAR Cancer, Edición 7, 2025, ISSN 2632-8674
Editor: Oxford University Press (OUP)
DOI: 10.1093/narcan/zcaf008

Long reads capture simultaneous enhancer-promoter methylation status for cell-type deconvolution

Autores: Sapir Margalit, Yotam Abramson, Hila Sharim, Zohar Manber, Surajit Bhattacharya, Yi-Wen Chen, Eric Vilain, Hayk Barseghyan, Ran Elkon, Roded Sharan, Yuval Ebenstein
Publicado en: Bioinformatics, 2021, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/btab306

Single-molecule toxicogenomics: Optical genome mapping of DNA-damage in nanochannel arrays

Autores: Tahir Detinis Zur, Sapir Margalit, Jonathan Jeffet, Assaf Grunwald, Sivan Fishman, Zuzana Tulpová, Yael Michaeli, Jasline Deek, Yuval Ebenstein
Publicado en: DNA Repair, Edición 146, 2025, Página(s) 103808, ISSN 1568-7864
Editor: Elsevier BV
DOI: 10.1016/j.dnarep.2025.103808

Chemo-Enzymatic Fluorescence Labeling Of Genomic DNA For Simultaneous Detection Of Global 5-Methylcytosine And 5-Hydroxymethylcytosine

Autores: Sigal Avraham, Dr. Leonie Schütz, Dr. Larissa Käver, Dr. Andreas Dankers, Sapir Margalit, Dr. Yael Michaeli, Dr. Shahar Zirkin, Dr. Dmitry Torchinsky, Dr. Noa Gilat, Omer Bahr, Gil Nifker, Prof. Maya Koren-Michowitz, Prof. Elmar Weinhold, Prof. Yuval Ebenstein
Publicado en: ChemBioChem, 2023, Página(s) e202300400, ISSN 1439-7633
Editor: Wiley-VCH
DOI: 10.1002/cbic.202300400

Machine-Learning-Based Single-Molecule Quantification of Circulating MicroRNA Mixtures

Autores: Jonathan Jeffet; Sayan Mondal; Amit Federbush; Nadav Tenenboim; Miriam Neaman; Jasline Deek; Yuval Ebenstein; Yohai Bar-Sinai
Publicado en: Crossref, Edición 1, 2023, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/acssensors.3c01234

Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

Autores: Tslil Gabrieli, Yael Michaeli, Sigal Avraham, Dmitry Torchinsky, Sapir Margalit, Leonie Schutz, Matyas Juhasz, Ceyda Coruh, Nissim Arbib, Zhaohui Sunny Zhou, Julie A. Law, Elmar Weinhold and Yuval Ebenstein
Publicado en: Nucleic Acids Research, 2022, ISSN 1362-4962
Editor: Oxford University Press
DOI: 10.1093/nar/gkac460

Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale

Autores: Jonathan Jeffet, Sapir Margalit, Yael Michaeli, Yuval Ebenstein
Publicado en: Essays in Biochemistry, Edición 65/1, 2021, Página(s) 51-66, ISSN 0071-1365
Editor: Portland Press, Ltd.
DOI: 10.1042/ebc20200021

Effective training of nanopore callers for epigenetic marks with limited labelled data

Autores: Brian Yao, Chloe Hsu, Gal Goldner, Yael Michaeli, Yuval Ebenstein and Jennifer Listgarten
Publicado en: Open Biology, 2024, ISSN 2046-2441
Editor: Royal Society Publishing
DOI: 10.1098/rsob.230449

DeepQR: single-molecule QR codes for optical gene-expression analysis

Autores: Jonathan Jeffet, Barak Hadad, Sahar Froim, Kawsar Kaboub, Keren M. Rabinowitz, Jasline Deek, Sapir Margalit, Iris Dotan, Alon Bahabad, Yuval Ebenstein
Publicado en: Nanophotonics, 2024, ISSN 2192-8606
Editor: Walter de Gruyter GmbH
DOI: 10.1515/nanoph-2024-0236

Single-molecule approaches for DNA damage detection and repair: A focus on Repair Assisted Damage Detection (RADD)

Autores: Tahir Detinis Zur; Jasline Deek; Yuval Ebenstein
Publicado en: Crossref, Edición 3, 2023, ISSN 1568-7864
Editor: Elsevier BV
DOI: 10.1016/j.dnarep.2023.103533

Nanopore callers for epigenetics from limited supervised data

Autores: Yao B; Chloe Ching-Yun Hsu; Goldner G; Yael Michaeli; Yuval Ebenstein; Jennifer Listgarten
Publicado en: Edición 1, 2021
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.06.17.448800

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