Excellence in research and development of non-coding RNA DIAGnostics in ONcology

Project Information

RNADIAGON

Grant agreement ID: 824036

DOI

10.3030/824036

Project closed

EC signature date 18 September 2018

Start date 1 February 2019

End date 31 July 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 662 400,00

EU contribution

€ 662 400,00

Coordinated by

Masarykova univerzita
Czechia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Exosomal small ncRNA profile from blood plasma/serum samples

Exosomal small ncRNA profile from blood plasmaserum samples

Standard Operating Protocol (SOP)

Standard Operating Protocol SOP defining appropriate methods and approaches in preanalytical management of blood samples RNA isolation small ncRNA detection and bioinformatics analysis

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (24)

Investigating Circular RNAs Using qRT-PCR; Roundup of Optimization and Processing Steps

Author(s): Rares Drula, Cornelia Braicu, Sergiu Chira, Ioana Berindan-Neagoe
Published in: International Journal of Molecular Sciences, Issue 24, 2023, Page(s) 5721, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065721

Recent advancements in the study of breast cancer exosomes as mediators of intratumoral communication

Author(s): Groza, M; Zimta, AA; Irimie, A; Achimas-Cadariu, P; Cenariu, D; Stanta, G; Berindan-Neagoe, I
Published in: JOURNAL OF CELLULAR PHYSIOLOGY, 2020, ISSN 0021-9541
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jcp.29096

circFOXO3: Going around the mechanistic networks in cancer by interfering with miRNAs regulatory networks

Author(s): Drula, R; Pirlog, R; Trif, M; Slaby, O; Braicu, C; Berindan-Neagoe, I
Published in: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2020.166045

Plasma and Tissue Specific miRNA Expression Pattern and Functional Analysis Associated to Colorectal Cancer Patients

Author(s): Cojocneanu, R; Braicu, C; Raduly, L; Jurj, A; Zanoaga, O; Magdo, L; Irimie, A; Muresan, MS; Ionescu, C; Grigorescu, M; Berindan-Neagoe, I
Published in: Cancers, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040843

Prognostic relevance of ABO blood group system in non-metastatic renal cell carcinoma: An analysis of two independent European cohorts with long-term follow-up

Author(s): Dominik A. Barth, Nazanin Sareban, Andrea K. Lindner, Louisa A.J. Daller, Eva Maria Matzhold, Georg Hutterer, Maria Smolle, Johannes Mischinger, Jakob M. Riedl, Maximilian Seles, Sebastian Mannweiler, Thomas Bauernhofer, Karl Pummer, Renate Pichler, Richard Zigeuner, Peter Schlenke, Martin Pichler
Published in: Urologic Oncology: Seminars and Original Investigations, Issue 39, 2021, Page(s) 736.e9-736.e16, ISSN 1078-1439
Publisher: Elsevier BV
DOI: 10.1016/j.urolonc.2021.06.005

Combination of Urinary MiR-501 and MiR-335 With Current Clinical Diagnostic Parameters as Potential Predictive Factors of Prostate Biopsy Outcome

Author(s): JAROSLAV JURACEK, MARIE MADRZYK, KAROLINA TRACHTOVA, MICHAELA RUCKOVA, JULIA BOHOSOVA, DOMINIK A. BARTH, MARTIN PICHLER, MICHAL STANIK, ONDREJ SLABY
Published in: Cancer Genomics - Proteomics, Issue 20, 2023, Page(s) 308-316, ISSN 1109-6535
Publisher: International Institute of Anticancer Research
DOI: 10.21873/cgp.20383

Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer

Author(s): Maximilian Seles, Georg C. Hutterer, Johannes Foßelteder, Marek Svoboda, Margit Resel, Dominik A. Barth, Renate Pichler, Thomas Bauernhofer, Richard E. Zigeuner, Karl Pummer, Ondrej Slaby, Christiane Klec, Martin Pichler
Published in: Cancers, Issue 12, 2024, Page(s) 1200, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12051200

Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers

Author(s): Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M
Published in: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, ISSN 2296-634X
Publisher: Frontiers Media
DOI: 10.3389/fcell.2020.00828

lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System.

Author(s): Dominik A. Barth; Jaroslav Juracek; Ondrej Slaby; Martin Pichler; Martin Pichler; George A. Calin
Published in: Cancers, Vol 12, Iss 2148, p 2148 (2020), Issue 2, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082148

Cellular and Molecular Profiling of Tumor Microenvironment and Early-Stage Lung Cancer

Author(s): Radu Pirlog, Paul Chiroi, Ioana Rusu, Ancuta Maria Jurj, Liviuta Budisan, Cecilia Pop-Bica, Cornelia Braicu, Doinita Crisan, Jean-Christophe Sabourin, Ioana Berindan-Neagoe
Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105346

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Author(s): Dominik A. Barth; Dominik A. Barth; Felix Prinz; Julia Teppan; Katharina Jonas; Christiane Klec; Martin Pichler; Martin Pichler
Published in: Cancers, Issue 2, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ncrna6030027

Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Author(s): Lucilla D’Abundo, Cristian Bassi, Elisa Callegari, Farzaneh Moshiri, Paola Guerriero, Angelo Michilli, Fernanda Mora, Andrea Casadei Gardini, Angelo Sangiovanni, Fabio Piscaglia, Silvia Sabbioni, Laura Gramantieri, Massimo Negrini
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-69548-4

Analysis of Differentially Expressed Genes, MMP3 and TESC, and Their Potential Value in Molecular Pathways in Colon Adenocarcinoma: A Bioinformatics Approach

Author(s): Constantin Busuioc, Andreea Nutu, Cornelia Braicu, Oana Zanoaga, Monica Trif, Ioana Berindan-Neagoe
Published in: BioMedInformatics, Issue 2, 2024, Page(s) 474-491, ISSN 2673-7426
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedinformatics2030030

Improved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up

Author(s): Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Published in: Therapeutic Advances in Medical Oncology, Issue 14, 2022, Page(s) 175883592211340, ISSN 1758-8359
Publisher: SAGE Publications
DOI: 10.1177/17588359221134065

MicroRNAs from Liquid Biopsy Derived Extracellular Vesicles: Recent Advances in Detection and Characterization Methods

Author(s): Drula, R; Ott, LF; Berindan-Neagoe, I; Pantel, K; Calin, GA
Published in: Cancers, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082009

Evaluation of miRNA detection methods for the analytical characteristic necessary for clinical utilization

Author(s): Iveta Krepelkova, Tereza Mrackova, Jana Izakova, Barbora Dvorakova, Lenka Chalupova, Robert Mikulik, Ondrej Slaby, Milan Bartos, Viktor Ruzicka
Published in: BioTechniques, Issue 66/6, 2019, Page(s) 277-284, ISSN 0736-6205
Publisher: Eaton Publishing Co.
DOI: 10.2144/btn-2019-0021

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma

Author(s): Dominik A. Barth, Ondrej Slaby, Christiane Klec, Jaroslav Juracek, Rares Drula, George A. Calin, Martin Pichler
Published in: Cancers, Issue 11/10, 2019, Page(s) 1580, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101580

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)

Author(s): Irimie-Aghiorghiesei, Pop-Bica, Pintea, Braicu, Cojocneanu, Zimța, Gulei, Slabý, Berindan-Neagoe
Published in: Journal of Clinical Medicine, Issue 8/12, 2019, Page(s) 2041, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8122041

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

Author(s): Braicu, Buse, Busuioc, Drula, Gulei, Raduly, Rusu, Irimie, Atanasov, Slaby, Ionescu, Berindan-Neagoe
Published in: Cancers, Issue 11/10, 2019, Page(s) 1618, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101618

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

Author(s): Bianca Oana Pirlog, Silvina Ilut, Radu Pirlog, Paul Chiroi, Andreea Nutu, Delia Ioana Radutiu, George Daniel Cuc, Ioana Berindan-Neagoe, Seyed Fazel Nabavi, Rosanna Filosa, Seyed Mohammad Nabavi
Published in: Expert Reviews in Molecular Medicine, Issue 25, 2023, ISSN 1462-3994
Publisher: Cambridge University Press
DOI: 10.1017/erm.2023.10

Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer

Author(s): Jurj, A; Pop-Bica, C; Slaby, O; Stefan, CD; Cho, WC; Korban, SS; Berindan-Neagoe, I
Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207688

17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer

Author(s): Rares Drula, Barbara Pardini, Xiao Fu, Mireia Cruz De los Santos, Ancuta Jurj, Lan Pang, Sherien M. El-Daly, Linda Fabris, Erik Knutsen, Mihnea P. Dragomir, Recep Bayraktar, Yongfeng Li, Meng Chen, Filippo Del Vecchio, Léa Berland, Jessica Dae, Daniel Fan, Masayoshi Shimizu, Anh M. Tran, Mercedes Barzi, Carlotta Pioppini, Angelica M. Gutierrez, Cristina Ivan, Salyna Meas, Carolyn S. Hall, Suresh
Published in: Proceedings of the National Academy of Sciences, Issue 120, 2023, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2122053120

At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets

Author(s): A. Jurj, D. Qian, G.A. Calin, K. Litchfield
Published in: Annals of Oncology, Issue 33, 2024, Page(s) 1214-1216, ISSN 0923-7534
Publisher: Oxford University Press
DOI: 10.1016/j.annonc.2022.10.507

Emerging roles and mechanisms of semaphorins activity in cancer

Author(s): Cecilia Bica, Alexandru Tirpe, Andreea Nutu, Cristina Ciocan, Sergiu Chira, Eugen S. Gurzau, Cornelia Braicu, Ioana Berindan-Neagoe
Published in: Life Sciences, Issue 318, 2024, Page(s) 121499, ISSN 0024-3205
Publisher: Elsevier BV
DOI: 10.1016/j.lfs.2023.121499