Excellence in research and development of non-coding RNA DIAGnostics in ONcology

Project Information

RNADIAGON

Grant agreement ID: 824036

DOI 10.3030/824036

EC signature date 18 September 2018

Start date 1 February 2019

End date 31 July 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 662 400,00

EU contribution € 662 400,00

Coordinated by

Masarykova univerzita
Czechia

Deliverables

Documents, reports (2)

Exosomal small ncRNA profile from blood plasma/serum samples

Exosomal small ncRNA profile from blood plasmaserum samples

Standard Operating Protocol (SOP)

Standard Operating Protocol SOP defining appropriate methods and approaches in preanalytical management of blood samples RNA isolation small ncRNA detection and bioinformatics analysis

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (13)

Recent advancements in the study of breast cancer exosomes as mediators of intratumoral communication

Author(s): Groza, M; Zimta, AA; Irimie, A; Achimas-Cadariu, P; Cenariu, D; Stanta, G; Berindan-Neagoe, I
Published in: JOURNAL OF CELLULAR PHYSIOLOGY, 2020, ISSN 0021-9541
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jcp.29096

circFOXO3: Going around the mechanistic networks in cancer by interfering with miRNAs regulatory networks

Author(s): Drula, R; Pirlog, R; Trif, M; Slaby, O; Braicu, C; Berindan-Neagoe, I
Published in: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2020.166045

Plasma and Tissue Specific miRNA Expression Pattern and Functional Analysis Associated to Colorectal Cancer Patients

Author(s): Cojocneanu, R; Braicu, C; Raduly, L; Jurj, A; Zanoaga, O; Magdo, L; Irimie, A; Muresan, MS; Ionescu, C; Grigorescu, M; Berindan-Neagoe, I
Published in: Cancers, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040843

Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers

Author(s): Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M
Published in: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, ISSN 2296-634X
Publisher: Frontiers Media
DOI: 10.3389/fcell.2020.00828

lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System.

Author(s): Dominik A. Barth; Jaroslav Juracek; Ondrej Slaby; Martin Pichler; Martin Pichler; George A. Calin
Published in: Cancers, Vol 12, Iss 2148, p 2148 (2020), Issue 2, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082148

Cellular and Molecular Profiling of Tumor Microenvironment and Early-Stage Lung Cancer

Author(s): Radu Pirlog, Paul Chiroi, Ioana Rusu, Ancuta Maria Jurj, Liviuta Budisan, Cecilia Pop-Bica, Cornelia Braicu, Doinita Crisan, Jean-Christophe Sabourin, Ioana Berindan-Neagoe
Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105346

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Author(s): Dominik A. Barth; Dominik A. Barth; Felix Prinz; Julia Teppan; Katharina Jonas; Christiane Klec; Martin Pichler; Martin Pichler
Published in: Cancers, Issue 2, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ncrna6030027

MicroRNAs from Liquid Biopsy Derived Extracellular Vesicles: Recent Advances in Detection and Characterization Methods

Author(s): Drula, R; Ott, LF; Berindan-Neagoe, I; Pantel, K; Calin, GA
Published in: Cancers, 2020, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082009

Evaluation of miRNA detection methods for the analytical characteristic necessary for clinical utilization

Author(s): Iveta Krepelkova, Tereza Mrackova, Jana Izakova, Barbora Dvorakova, Lenka Chalupova, Robert Mikulik, Ondrej Slaby, Milan Bartos, Viktor Ruzicka
Published in: BioTechniques, Issue 66/6, 2019, Page(s) 277-284, ISSN 0736-6205
Publisher: Eaton Publishing Co.
DOI: 10.2144/btn-2019-0021

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma

Author(s): Dominik A. Barth, Ondrej Slaby, Christiane Klec, Jaroslav Juracek, Rares Drula, George A. Calin, Martin Pichler
Published in: Cancers, Issue 11/10, 2019, Page(s) 1580, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101580

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)

Author(s): Irimie-Aghiorghiesei, Pop-Bica, Pintea, Braicu, Cojocneanu, Zimța, Gulei, Slabý, Berindan-Neagoe
Published in: Journal of Clinical Medicine, Issue 8/12, 2019, Page(s) 2041, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8122041

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

Author(s): Braicu, Buse, Busuioc, Drula, Gulei, Raduly, Rusu, Irimie, Atanasov, Slaby, Ionescu, Berindan-Neagoe
Published in: Cancers, Issue 11/10, 2019, Page(s) 1618, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101618

Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer

Author(s): Jurj, A; Pop-Bica, C; Slaby, O; Stefan, CD; Cho, WC; Korban, SS; Berindan-Neagoe, I
Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207688