Excellence in research and development of non-coding RNA DIAGnostics in ONcology

Informazioni relative al progetto

RNADIAGON

ID dell’accordo di sovvenzione: 824036

DOI

10.3030/824036

Progetto chiuso

Data della firma CE 18 Settembre 2018

Data di avvio 1 Febbraio 2019

Data di completamento 31 Luglio 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 662 400,00

Contributo UE

€ 662 400,00

Coordinato da

Masarykova univerzita
Czechia

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (2)

Exosomal small ncRNA profile from blood plasma/serum samples

Exosomal small ncRNA profile from blood plasmaserum samples

Standard Operating Protocol (SOP)

Standard Operating Protocol SOP defining appropriate methods and approaches in preanalytical management of blood samples RNA isolation small ncRNA detection and bioinformatics analysis

Open Research Data Pilot (1)

Data Management Plan

Pubblicazioni

Peer reviewed articles (24)

Investigating Circular RNAs Using qRT-PCR; Roundup of Optimization and Processing Steps

Autori: Rares Drula, Cornelia Braicu, Sergiu Chira, Ioana Berindan-Neagoe
Pubblicato in: International Journal of Molecular Sciences, Numero 24, 2023, Pagina/e 5721, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065721

Recent advancements in the study of breast cancer exosomes as mediators of intratumoral communication

Autori: Groza, M; Zimta, AA; Irimie, A; Achimas-Cadariu, P; Cenariu, D; Stanta, G; Berindan-Neagoe, I
Pubblicato in: JOURNAL OF CELLULAR PHYSIOLOGY, 2020, ISSN 0021-9541
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jcp.29096

circFOXO3: Going around the mechanistic networks in cancer by interfering with miRNAs regulatory networks

Autori: Drula, R; Pirlog, R; Trif, M; Slaby, O; Braicu, C; Berindan-Neagoe, I
Pubblicato in: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, ISSN 0925-4439
Editore: Elsevier BV
DOI: 10.1016/j.bbadis.2020.166045

Plasma and Tissue Specific miRNA Expression Pattern and Functional Analysis Associated to Colorectal Cancer Patients

Autori: Cojocneanu, R; Braicu, C; Raduly, L; Jurj, A; Zanoaga, O; Magdo, L; Irimie, A; Muresan, MS; Ionescu, C; Grigorescu, M; Berindan-Neagoe, I
Pubblicato in: Cancers, 2020, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040843

Prognostic relevance of ABO blood group system in non-metastatic renal cell carcinoma: An analysis of two independent European cohorts with long-term follow-up

Autori: Dominik A. Barth, Nazanin Sareban, Andrea K. Lindner, Louisa A.J. Daller, Eva Maria Matzhold, Georg Hutterer, Maria Smolle, Johannes Mischinger, Jakob M. Riedl, Maximilian Seles, Sebastian Mannweiler, Thomas Bauernhofer, Karl Pummer, Renate Pichler, Richard Zigeuner, Peter Schlenke, Martin Pichler
Pubblicato in: Urologic Oncology: Seminars and Original Investigations, Numero 39, 2021, Pagina/e 736.e9-736.e16, ISSN 1078-1439
Editore: Elsevier BV
DOI: 10.1016/j.urolonc.2021.06.005

Combination of Urinary MiR-501 and MiR-335 With Current Clinical Diagnostic Parameters as Potential Predictive Factors of Prostate Biopsy Outcome

Autori: JAROSLAV JURACEK, MARIE MADRZYK, KAROLINA TRACHTOVA, MICHAELA RUCKOVA, JULIA BOHOSOVA, DOMINIK A. BARTH, MARTIN PICHLER, MICHAL STANIK, ONDREJ SLABY
Pubblicato in: Cancer Genomics - Proteomics, Numero 20, 2023, Pagina/e 308-316, ISSN 1109-6535
Editore: International Institute of Anticancer Research
DOI: 10.21873/cgp.20383

Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer

Autori: Maximilian Seles, Georg C. Hutterer, Johannes Foßelteder, Marek Svoboda, Margit Resel, Dominik A. Barth, Renate Pichler, Thomas Bauernhofer, Richard E. Zigeuner, Karl Pummer, Ondrej Slaby, Christiane Klec, Martin Pichler
Pubblicato in: Cancers, Numero 12, 2024, Pagina/e 1200, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12051200

Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers

Autori: Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M
Pubblicato in: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, ISSN 2296-634X
Editore: Frontiers Media
DOI: 10.3389/fcell.2020.00828

lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System.

Autori: Dominik A. Barth; Jaroslav Juracek; Ondrej Slaby; Martin Pichler; Martin Pichler; George A. Calin
Pubblicato in: Cancers, Vol 12, Iss 2148, p 2148 (2020), Numero 2, 2020, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082148

Cellular and Molecular Profiling of Tumor Microenvironment and Early-Stage Lung Cancer

Autori: Radu Pirlog, Paul Chiroi, Ioana Rusu, Ancuta Maria Jurj, Liviuta Budisan, Cecilia Pop-Bica, Cornelia Braicu, Doinita Crisan, Jean-Christophe Sabourin, Ioana Berindan-Neagoe
Pubblicato in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105346

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Autori: Dominik A. Barth; Dominik A. Barth; Felix Prinz; Julia Teppan; Katharina Jonas; Christiane Klec; Martin Pichler; Martin Pichler
Pubblicato in: Cancers, Numero 2, 2020, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ncrna6030027

Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Autori: Lucilla D’Abundo, Cristian Bassi, Elisa Callegari, Farzaneh Moshiri, Paola Guerriero, Angelo Michilli, Fernanda Mora, Andrea Casadei Gardini, Angelo Sangiovanni, Fabio Piscaglia, Silvia Sabbioni, Laura Gramantieri, Massimo Negrini
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-69548-4

Analysis of Differentially Expressed Genes, MMP3 and TESC, and Their Potential Value in Molecular Pathways in Colon Adenocarcinoma: A Bioinformatics Approach

Autori: Constantin Busuioc, Andreea Nutu, Cornelia Braicu, Oana Zanoaga, Monica Trif, Ioana Berindan-Neagoe
Pubblicato in: BioMedInformatics, Numero 2, 2024, Pagina/e 474-491, ISSN 2673-7426
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedinformatics2030030

Improved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up

Autori: Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Pubblicato in: Therapeutic Advances in Medical Oncology, Numero 14, 2022, Pagina/e 175883592211340, ISSN 1758-8359
Editore: SAGE Publications
DOI: 10.1177/17588359221134065

MicroRNAs from Liquid Biopsy Derived Extracellular Vesicles: Recent Advances in Detection and Characterization Methods

Autori: Drula, R; Ott, LF; Berindan-Neagoe, I; Pantel, K; Calin, GA
Pubblicato in: Cancers, 2020, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082009

Evaluation of miRNA detection methods for the analytical characteristic necessary for clinical utilization

Autori: Iveta Krepelkova, Tereza Mrackova, Jana Izakova, Barbora Dvorakova, Lenka Chalupova, Robert Mikulik, Ondrej Slaby, Milan Bartos, Viktor Ruzicka
Pubblicato in: BioTechniques, Numero 66/6, 2019, Pagina/e 277-284, ISSN 0736-6205
Editore: Eaton Publishing Co.
DOI: 10.2144/btn-2019-0021

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma

Autori: Dominik A. Barth, Ondrej Slaby, Christiane Klec, Jaroslav Juracek, Rares Drula, George A. Calin, Martin Pichler
Pubblicato in: Cancers, Numero 11/10, 2019, Pagina/e 1580, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101580

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)

Autori: Irimie-Aghiorghiesei, Pop-Bica, Pintea, Braicu, Cojocneanu, Zimța, Gulei, Slabý, Berindan-Neagoe
Pubblicato in: Journal of Clinical Medicine, Numero 8/12, 2019, Pagina/e 2041, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8122041

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

Autori: Braicu, Buse, Busuioc, Drula, Gulei, Raduly, Rusu, Irimie, Atanasov, Slaby, Ionescu, Berindan-Neagoe
Pubblicato in: Cancers, Numero 11/10, 2019, Pagina/e 1618, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101618

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

Autori: Bianca Oana Pirlog, Silvina Ilut, Radu Pirlog, Paul Chiroi, Andreea Nutu, Delia Ioana Radutiu, George Daniel Cuc, Ioana Berindan-Neagoe, Seyed Fazel Nabavi, Rosanna Filosa, Seyed Mohammad Nabavi
Pubblicato in: Expert Reviews in Molecular Medicine, Numero 25, 2023, ISSN 1462-3994
Editore: Cambridge University Press
DOI: 10.1017/erm.2023.10

Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer

Autori: Jurj, A; Pop-Bica, C; Slaby, O; Stefan, CD; Cho, WC; Korban, SS; Berindan-Neagoe, I
Pubblicato in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207688

17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer

Autori: Rares Drula, Barbara Pardini, Xiao Fu, Mireia Cruz De los Santos, Ancuta Jurj, Lan Pang, Sherien M. El-Daly, Linda Fabris, Erik Knutsen, Mihnea P. Dragomir, Recep Bayraktar, Yongfeng Li, Meng Chen, Filippo Del Vecchio, Léa Berland, Jessica Dae, Daniel Fan, Masayoshi Shimizu, Anh M. Tran, Mercedes Barzi, Carlotta Pioppini, Angelica M. Gutierrez, Cristina Ivan, Salyna Meas, Carolyn S. Hall, Suresh
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 120, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2122053120

At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets

Autori: A. Jurj, D. Qian, G.A. Calin, K. Litchfield
Pubblicato in: Annals of Oncology, Numero 33, 2024, Pagina/e 1214-1216, ISSN 0923-7534
Editore: Oxford University Press
DOI: 10.1016/j.annonc.2022.10.507

Emerging roles and mechanisms of semaphorins activity in cancer

Autori: Cecilia Bica, Alexandru Tirpe, Andreea Nutu, Cristina Ciocan, Sergiu Chira, Eugen S. Gurzau, Cornelia Braicu, Ioana Berindan-Neagoe
Pubblicato in: Life Sciences, Numero 318, 2024, Pagina/e 121499, ISSN 0024-3205
Editore: Elsevier BV
DOI: 10.1016/j.lfs.2023.121499