Excellence in research and development of non-coding RNA DIAGnostics in ONcology

Informations projet

RNADIAGON

N° de convention de subvention: 824036

DOI

10.3030/824036

Projet clôturé

Date de signature de la CE 18 Septembre 2018

Date de début 1 Février 2019

Date de fin 31 Juillet 2024

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 662 400,00

Contribution de l’UE

€ 662 400,00

Coordonné par

Masarykova univerzita
Czechia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (2)

Exosomal small ncRNA profile from blood plasma/serum samples

Exosomal small ncRNA profile from blood plasmaserum samples

Standard Operating Protocol (SOP)

Standard Operating Protocol SOP defining appropriate methods and approaches in preanalytical management of blood samples RNA isolation small ncRNA detection and bioinformatics analysis

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (24)

Investigating Circular RNAs Using qRT-PCR; Roundup of Optimization and Processing Steps

Auteurs: Rares Drula, Cornelia Braicu, Sergiu Chira, Ioana Berindan-Neagoe
Publié dans: International Journal of Molecular Sciences, Numéro 24, 2023, Page(s) 5721, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065721

Recent advancements in the study of breast cancer exosomes as mediators of intratumoral communication

Auteurs: Groza, M; Zimta, AA; Irimie, A; Achimas-Cadariu, P; Cenariu, D; Stanta, G; Berindan-Neagoe, I
Publié dans: JOURNAL OF CELLULAR PHYSIOLOGY, 2020, ISSN 0021-9541
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jcp.29096

circFOXO3: Going around the mechanistic networks in cancer by interfering with miRNAs regulatory networks

Auteurs: Drula, R; Pirlog, R; Trif, M; Slaby, O; Braicu, C; Berindan-Neagoe, I
Publié dans: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, ISSN 0925-4439
Éditeur: Elsevier BV
DOI: 10.1016/j.bbadis.2020.166045

Plasma and Tissue Specific miRNA Expression Pattern and Functional Analysis Associated to Colorectal Cancer Patients

Auteurs: Cojocneanu, R; Braicu, C; Raduly, L; Jurj, A; Zanoaga, O; Magdo, L; Irimie, A; Muresan, MS; Ionescu, C; Grigorescu, M; Berindan-Neagoe, I
Publié dans: Cancers, 2020, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040843

Prognostic relevance of ABO blood group system in non-metastatic renal cell carcinoma: An analysis of two independent European cohorts with long-term follow-up

Auteurs: Dominik A. Barth, Nazanin Sareban, Andrea K. Lindner, Louisa A.J. Daller, Eva Maria Matzhold, Georg Hutterer, Maria Smolle, Johannes Mischinger, Jakob M. Riedl, Maximilian Seles, Sebastian Mannweiler, Thomas Bauernhofer, Karl Pummer, Renate Pichler, Richard Zigeuner, Peter Schlenke, Martin Pichler
Publié dans: Urologic Oncology: Seminars and Original Investigations, Numéro 39, 2021, Page(s) 736.e9-736.e16, ISSN 1078-1439
Éditeur: Elsevier BV
DOI: 10.1016/j.urolonc.2021.06.005

Combination of Urinary MiR-501 and MiR-335 With Current Clinical Diagnostic Parameters as Potential Predictive Factors of Prostate Biopsy Outcome

Auteurs: JAROSLAV JURACEK, MARIE MADRZYK, KAROLINA TRACHTOVA, MICHAELA RUCKOVA, JULIA BOHOSOVA, DOMINIK A. BARTH, MARTIN PICHLER, MICHAL STANIK, ONDREJ SLABY
Publié dans: Cancer Genomics - Proteomics, Numéro 20, 2023, Page(s) 308-316, ISSN 1109-6535
Éditeur: International Institute of Anticancer Research
DOI: 10.21873/cgp.20383

Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer

Auteurs: Maximilian Seles, Georg C. Hutterer, Johannes Foßelteder, Marek Svoboda, Margit Resel, Dominik A. Barth, Renate Pichler, Thomas Bauernhofer, Richard E. Zigeuner, Karl Pummer, Ondrej Slaby, Christiane Klec, Martin Pichler
Publié dans: Cancers, Numéro 12, 2024, Page(s) 1200, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12051200

Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers

Auteurs: Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M
Publié dans: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, ISSN 2296-634X
Éditeur: Frontiers Media
DOI: 10.3389/fcell.2020.00828

lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System.

Auteurs: Dominik A. Barth; Jaroslav Juracek; Ondrej Slaby; Martin Pichler; Martin Pichler; George A. Calin
Publié dans: Cancers, Vol 12, Iss 2148, p 2148 (2020), Numéro 2, 2020, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082148

Cellular and Molecular Profiling of Tumor Microenvironment and Early-Stage Lung Cancer

Auteurs: Radu Pirlog, Paul Chiroi, Ioana Rusu, Ancuta Maria Jurj, Liviuta Budisan, Cecilia Pop-Bica, Cornelia Braicu, Doinita Crisan, Jean-Christophe Sabourin, Ioana Berindan-Neagoe
Publié dans: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105346

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Auteurs: Dominik A. Barth; Dominik A. Barth; Felix Prinz; Julia Teppan; Katharina Jonas; Christiane Klec; Martin Pichler; Martin Pichler
Publié dans: Cancers, Numéro 2, 2020, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ncrna6030027

Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Auteurs: Lucilla D’Abundo, Cristian Bassi, Elisa Callegari, Farzaneh Moshiri, Paola Guerriero, Angelo Michilli, Fernanda Mora, Andrea Casadei Gardini, Angelo Sangiovanni, Fabio Piscaglia, Silvia Sabbioni, Laura Gramantieri, Massimo Negrini
Publié dans: Scientific Reports, Numéro 14, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-69548-4

Analysis of Differentially Expressed Genes, MMP3 and TESC, and Their Potential Value in Molecular Pathways in Colon Adenocarcinoma: A Bioinformatics Approach

Auteurs: Constantin Busuioc, Andreea Nutu, Cornelia Braicu, Oana Zanoaga, Monica Trif, Ioana Berindan-Neagoe
Publié dans: BioMedInformatics, Numéro 2, 2024, Page(s) 474-491, ISSN 2673-7426
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedinformatics2030030

Improved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up

Auteurs: Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Publié dans: Therapeutic Advances in Medical Oncology, Numéro 14, 2022, Page(s) 175883592211340, ISSN 1758-8359
Éditeur: SAGE Publications
DOI: 10.1177/17588359221134065

MicroRNAs from Liquid Biopsy Derived Extracellular Vesicles: Recent Advances in Detection and Characterization Methods

Auteurs: Drula, R; Ott, LF; Berindan-Neagoe, I; Pantel, K; Calin, GA
Publié dans: Cancers, 2020, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082009

Evaluation of miRNA detection methods for the analytical characteristic necessary for clinical utilization

Auteurs: Iveta Krepelkova, Tereza Mrackova, Jana Izakova, Barbora Dvorakova, Lenka Chalupova, Robert Mikulik, Ondrej Slaby, Milan Bartos, Viktor Ruzicka
Publié dans: BioTechniques, Numéro 66/6, 2019, Page(s) 277-284, ISSN 0736-6205
Éditeur: Eaton Publishing Co.
DOI: 10.2144/btn-2019-0021

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma

Auteurs: Dominik A. Barth, Ondrej Slaby, Christiane Klec, Jaroslav Juracek, Rares Drula, George A. Calin, Martin Pichler
Publié dans: Cancers, Numéro 11/10, 2019, Page(s) 1580, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101580

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)

Auteurs: Irimie-Aghiorghiesei, Pop-Bica, Pintea, Braicu, Cojocneanu, Zimța, Gulei, Slabý, Berindan-Neagoe
Publié dans: Journal of Clinical Medicine, Numéro 8/12, 2019, Page(s) 2041, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8122041

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

Auteurs: Braicu, Buse, Busuioc, Drula, Gulei, Raduly, Rusu, Irimie, Atanasov, Slaby, Ionescu, Berindan-Neagoe
Publié dans: Cancers, Numéro 11/10, 2019, Page(s) 1618, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101618

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

Auteurs: Bianca Oana Pirlog, Silvina Ilut, Radu Pirlog, Paul Chiroi, Andreea Nutu, Delia Ioana Radutiu, George Daniel Cuc, Ioana Berindan-Neagoe, Seyed Fazel Nabavi, Rosanna Filosa, Seyed Mohammad Nabavi
Publié dans: Expert Reviews in Molecular Medicine, Numéro 25, 2023, ISSN 1462-3994
Éditeur: Cambridge University Press
DOI: 10.1017/erm.2023.10

Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer

Auteurs: Jurj, A; Pop-Bica, C; Slaby, O; Stefan, CD; Cho, WC; Korban, SS; Berindan-Neagoe, I
Publié dans: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207688

17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer

Auteurs: Rares Drula, Barbara Pardini, Xiao Fu, Mireia Cruz De los Santos, Ancuta Jurj, Lan Pang, Sherien M. El-Daly, Linda Fabris, Erik Knutsen, Mihnea P. Dragomir, Recep Bayraktar, Yongfeng Li, Meng Chen, Filippo Del Vecchio, Léa Berland, Jessica Dae, Daniel Fan, Masayoshi Shimizu, Anh M. Tran, Mercedes Barzi, Carlotta Pioppini, Angelica M. Gutierrez, Cristina Ivan, Salyna Meas, Carolyn S. Hall, Suresh
Publié dans: Proceedings of the National Academy of Sciences, Numéro 120, 2023, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.2122053120

At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets

Auteurs: A. Jurj, D. Qian, G.A. Calin, K. Litchfield
Publié dans: Annals of Oncology, Numéro 33, 2024, Page(s) 1214-1216, ISSN 0923-7534
Éditeur: Oxford University Press
DOI: 10.1016/j.annonc.2022.10.507

Emerging roles and mechanisms of semaphorins activity in cancer

Auteurs: Cecilia Bica, Alexandru Tirpe, Andreea Nutu, Cristina Ciocan, Sergiu Chira, Eugen S. Gurzau, Cornelia Braicu, Ioana Berindan-Neagoe
Publié dans: Life Sciences, Numéro 318, 2024, Page(s) 121499, ISSN 0024-3205
Éditeur: Elsevier BV
DOI: 10.1016/j.lfs.2023.121499