Excellence in research and development of non-coding RNA DIAGnostics in ONcology

Resultado final

Exosomal small ncRNA profile from blood plasma/serum samples

Exosomal small ncRNA profile from blood plasmaserum samples

Standard Operating Protocol SOP defining appropriate methods and approaches in preanalytical management of blood samples RNA isolation small ncRNA detection and bioinformatics analysis

Data Management Plan

Publicaciones

Investigating Circular RNAs Using qRT-PCR; Roundup of Optimization and Processing Steps

Autores: Rares Drula, Cornelia Braicu, Sergiu Chira, Ioana Berindan-Neagoe
Publicado en: International Journal of Molecular Sciences, Edición 24, 2023, Página(s) 5721, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065721

Recent advancements in the study of breast cancer exosomes as mediators of intratumoral communication

Autores: Groza, M; Zimta, AA; Irimie, A; Achimas-Cadariu, P; Cenariu, D; Stanta, G; Berindan-Neagoe, I
Publicado en: JOURNAL OF CELLULAR PHYSIOLOGY, 2020, ISSN 0021-9541
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jcp.29096

circFOXO3: Going around the mechanistic networks in cancer by interfering with miRNAs regulatory networks

Autores: Drula, R; Pirlog, R; Trif, M; Slaby, O; Braicu, C; Berindan-Neagoe, I
Publicado en: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021, ISSN 0925-4439
Editor: Elsevier BV
DOI: 10.1016/j.bbadis.2020.166045

Plasma and Tissue Specific miRNA Expression Pattern and Functional Analysis Associated to Colorectal Cancer Patients

Autores: Cojocneanu, R; Braicu, C; Raduly, L; Jurj, A; Zanoaga, O; Magdo, L; Irimie, A; Muresan, MS; Ionescu, C; Grigorescu, M; Berindan-Neagoe, I
Publicado en: Cancers, 2020, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040843

Prognostic relevance of ABO blood group system in non-metastatic renal cell carcinoma: An analysis of two independent European cohorts with long-term follow-up

Autores: Dominik A. Barth, Nazanin Sareban, Andrea K. Lindner, Louisa A.J. Daller, Eva Maria Matzhold, Georg Hutterer, Maria Smolle, Johannes Mischinger, Jakob M. Riedl, Maximilian Seles, Sebastian Mannweiler, Thomas Bauernhofer, Karl Pummer, Renate Pichler, Richard Zigeuner, Peter Schlenke, Martin Pichler
Publicado en: Urologic Oncology: Seminars and Original Investigations, Edición 39, 2021, Página(s) 736.e9-736.e16, ISSN 1078-1439
Editor: Elsevier BV
DOI: 10.1016/j.urolonc.2021.06.005

Combination of Urinary MiR-501 and MiR-335 With Current Clinical Diagnostic Parameters as Potential Predictive Factors of Prostate Biopsy Outcome

Autores: JAROSLAV JURACEK, MARIE MADRZYK, KAROLINA TRACHTOVA, MICHAELA RUCKOVA, JULIA BOHOSOVA, DOMINIK A. BARTH, MARTIN PICHLER, MICHAL STANIK, ONDREJ SLABY
Publicado en: Cancer Genomics - Proteomics, Edición 20, 2023, Página(s) 308-316, ISSN 1109-6535
Editor: International Institute of Anticancer Research
DOI: 10.21873/cgp.20383

Long Non-Coding RNA PANTR1 is Associated with Poor Prognosis and Influences Angiogenesis and Apoptosis in Clear-Cell Renal Cell Cancer

Autores: Maximilian Seles, Georg C. Hutterer, Johannes Foßelteder, Marek Svoboda, Margit Resel, Dominik A. Barth, Renate Pichler, Thomas Bauernhofer, Richard E. Zigeuner, Karl Pummer, Ondrej Slaby, Christiane Klec, Martin Pichler
Publicado en: Cancers, Edición 12, 2024, Página(s) 1200, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12051200

Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers

Autores: Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M
Publicado en: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, ISSN 2296-634X
Editor: Frontiers Media
DOI: 10.3389/fcell.2020.00828

lncRNA and Mechanisms of Drug Resistance in Cancers of the Genitourinary System.

Autores: Dominik A. Barth; Jaroslav Juracek; Ondrej Slaby; Martin Pichler; Martin Pichler; George A. Calin
Publicado en: Cancers, Vol 12, Iss 2148, p 2148 (2020), Edición 2, 2020, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082148

Cellular and Molecular Profiling of Tumor Microenvironment and Early-Stage Lung Cancer

Autores: Radu Pirlog, Paul Chiroi, Ioana Rusu, Ancuta Maria Jurj, Liviuta Budisan, Cecilia Pop-Bica, Cornelia Braicu, Doinita Crisan, Jean-Christophe Sabourin, Ioana Berindan-Neagoe
Publicado en: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105346

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Autores: Dominik A. Barth; Dominik A. Barth; Felix Prinz; Julia Teppan; Katharina Jonas; Christiane Klec; Martin Pichler; Martin Pichler
Publicado en: Cancers, Edición 2, 2020, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ncrna6030027

Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapy

Autores: Lucilla D’Abundo, Cristian Bassi, Elisa Callegari, Farzaneh Moshiri, Paola Guerriero, Angelo Michilli, Fernanda Mora, Andrea Casadei Gardini, Angelo Sangiovanni, Fabio Piscaglia, Silvia Sabbioni, Laura Gramantieri, Massimo Negrini
Publicado en: Scientific Reports, Edición 14, 2024, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-024-69548-4

Analysis of Differentially Expressed Genes, MMP3 and TESC, and Their Potential Value in Molecular Pathways in Colon Adenocarcinoma: A Bioinformatics Approach

Autores: Constantin Busuioc, Andreea Nutu, Cornelia Braicu, Oana Zanoaga, Monica Trif, Ioana Berindan-Neagoe
Publicado en: BioMedInformatics, Edición 2, 2024, Página(s) 474-491, ISSN 2673-7426
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedinformatics2030030

Improved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up

Autores: Hannah Fluhrer, Georg C. Hutterer, Sylvia Golbeck, Michael Stidl, Tobias Niedrist, Renate Pichler, Johannes Mischinger, Maximilian Seles, Sebastian Mannweiler, Jasmin Spiegelberg, Thomas Bauernhofer, Philipp J. Jost, Sascha Ahyai, Richard Zigeuner, Martin Pichler, Dominik A. Barth
Publicado en: Therapeutic Advances in Medical Oncology, Edición 14, 2022, Página(s) 175883592211340, ISSN 1758-8359
Editor: SAGE Publications
DOI: 10.1177/17588359221134065

MicroRNAs from Liquid Biopsy Derived Extracellular Vesicles: Recent Advances in Detection and Characterization Methods

Autores: Drula, R; Ott, LF; Berindan-Neagoe, I; Pantel, K; Calin, GA
Publicado en: Cancers, 2020, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082009

Evaluation of miRNA detection methods for the analytical characteristic necessary for clinical utilization

Autores: Iveta Krepelkova, Tereza Mrackova, Jana Izakova, Barbora Dvorakova, Lenka Chalupova, Robert Mikulik, Ondrej Slaby, Milan Bartos, Viktor Ruzicka
Publicado en: BioTechniques, Edición 66/6, 2019, Página(s) 277-284, ISSN 0736-6205
Editor: Eaton Publishing Co.
DOI: 10.2144/btn-2019-0021

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma

Autores: Dominik A. Barth, Ondrej Slaby, Christiane Klec, Jaroslav Juracek, Rares Drula, George A. Calin, Martin Pichler
Publicado en: Cancers, Edición 11/10, 2019, Página(s) 1580, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101580

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)

Autores: Irimie-Aghiorghiesei, Pop-Bica, Pintea, Braicu, Cojocneanu, Zimța, Gulei, Slabý, Berindan-Neagoe
Publicado en: Journal of Clinical Medicine, Edición 8/12, 2019, Página(s) 2041, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8122041

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

Autores: Braicu, Buse, Busuioc, Drula, Gulei, Raduly, Rusu, Irimie, Atanasov, Slaby, Ionescu, Berindan-Neagoe
Publicado en: Cancers, Edición 11/10, 2019, Página(s) 1618, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101618

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

Autores: Bianca Oana Pirlog, Silvina Ilut, Radu Pirlog, Paul Chiroi, Andreea Nutu, Delia Ioana Radutiu, George Daniel Cuc, Ioana Berindan-Neagoe, Seyed Fazel Nabavi, Rosanna Filosa, Seyed Mohammad Nabavi
Publicado en: Expert Reviews in Molecular Medicine, Edición 25, 2023, ISSN 1462-3994
Editor: Cambridge University Press
DOI: 10.1017/erm.2023.10

Tiny Actors in the Big Cellular World: Extracellular Vesicles Playing Critical Roles in Cancer

Autores: Jurj, A; Pop-Bica, C; Slaby, O; Stefan, CD; Cho, WC; Korban, SS; Berindan-Neagoe, I
Publicado en: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207688

17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer

Autores: Rares Drula, Barbara Pardini, Xiao Fu, Mireia Cruz De los Santos, Ancuta Jurj, Lan Pang, Sherien M. El-Daly, Linda Fabris, Erik Knutsen, Mihnea P. Dragomir, Recep Bayraktar, Yongfeng Li, Meng Chen, Filippo Del Vecchio, Léa Berland, Jessica Dae, Daniel Fan, Masayoshi Shimizu, Anh M. Tran, Mercedes Barzi, Carlotta Pioppini, Angelica M. Gutierrez, Cristina Ivan, Salyna Meas, Carolyn S. Hall, Suresh
Publicado en: Proceedings of the National Academy of Sciences, Edición 120, 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2122053120

At the crossroad between checkpoint blockade and big data analyses: identification of novel biomarkers and potential targets

Autores: A. Jurj, D. Qian, G.A. Calin, K. Litchfield
Publicado en: Annals of Oncology, Edición 33, 2024, Página(s) 1214-1216, ISSN 0923-7534
Editor: Oxford University Press
DOI: 10.1016/j.annonc.2022.10.507

Emerging roles and mechanisms of semaphorins activity in cancer

Autores: Cecilia Bica, Alexandru Tirpe, Andreea Nutu, Cristina Ciocan, Sergiu Chira, Eugen S. Gurzau, Cornelia Braicu, Ioana Berindan-Neagoe
Publicado en: Life Sciences, Edición 318, 2024, Página(s) 121499, ISSN 0024-3205
Editor: Elsevier BV
DOI: 10.1016/j.lfs.2023.121499

Resultado final

Publicaciones

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